Motif ID: Plag1

Z-value: 0.673


Transcription factors associated with Plag1:

Gene SymbolEntrez IDGene Name
Plag1 ENSMUSG00000003282.3 Plag1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Plag1mm10_v2_chr4_-_3938354_39384010.195.2e-01Click!


Activity profile for motif Plag1.

activity profile for motif Plag1


Sorted Z-values histogram for motif Plag1

Sorted Z-values for motif Plag1



Network of associatons between targets according to the STRING database.



First level regulatory network of Plag1

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr15_-_78544345 1.527 ENSMUST00000053239.2
 Sstr3
somatostatin receptor 3
chr17_+_72918298 0.863 ENSMUST00000024857.6
 Lbh
limb-bud and heart
chrX_-_166585679 0.848 ENSMUST00000000412.2
 Egfl6
EGF-like-domain, multiple 6
chr11_-_95587691 0.828 ENSMUST00000000122.6
 Ngfr
nerve growth factor receptor (TNFR superfamily, member 16)
chr11_+_77930800 0.751 ENSMUST00000093995.3
ENSMUST00000000646.7
 Sez6

seizure related gene 6

chr17_-_87797994 0.678 ENSMUST00000055221.7
 Kcnk12
potassium channel, subfamily K, member 12
chr15_-_84856043 0.676 ENSMUST00000159939.1
 Phf21b
PHD finger protein 21B
chr11_-_22001605 0.657 ENSMUST00000006071.7
 Otx1
orthodenticle homolog 1 (Drosophila)
chr12_-_45074112 0.646 ENSMUST00000120531.1
ENSMUST00000143376.1
 Stxbp6

syntaxin binding protein 6 (amisyn)

chr8_-_87959560 0.644 ENSMUST00000109655.2
 Zfp423
zinc finger protein 423
chr18_+_82914632 0.642 ENSMUST00000071233.6
 Zfp516
zinc finger protein 516
chr1_-_172057573 0.632 ENSMUST00000059794.3
 Nhlh1
nescient helix loop helix 1
chr6_-_48841373 0.627 ENSMUST00000166247.1
 Tmem176b
transmembrane protein 176B
chr19_-_41743665 0.576 ENSMUST00000025993.3
 Slit1
slit homolog 1 (Drosophila)
chr6_+_120666388 0.574 ENSMUST00000112686.1
 Cecr2
cat eye syndrome chromosome region, candidate 2
chr6_-_48841098 0.556 ENSMUST00000101429.4
 Tmem176b
transmembrane protein 176B
chr15_+_40655020 0.541 ENSMUST00000053467.4
 Zfpm2
zinc finger protein, multitype 2
chr14_-_30626196 0.517 ENSMUST00000112210.3
ENSMUST00000112211.2
ENSMUST00000112208.1
 Prkcd


protein kinase C, delta


chr3_+_153973436 0.507 ENSMUST00000089948.5
 Slc44a5
solute carrier family 44, member 5
chr15_-_85581809 0.494 ENSMUST00000023015.7
 Wnt7b
wingless-related MMTV integration site 7B

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 186 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 1.5 GO:0007218 neuropeptide signaling pathway(GO:0007218)
0.2 1.4 GO:2001199 negative regulation of dendritic cell differentiation(GO:2001199)
0.1 1.3 GO:0090036 regulation of protein kinase C signaling(GO:0090036)
0.1 1.1 GO:0035542 regulation of SNARE complex assembly(GO:0035542)
0.3 0.9 GO:0051902 negative regulation of mitochondrial depolarization(GO:0051902) negative regulation of membrane depolarization(GO:1904180)
0.2 0.8 GO:0006680 glucosylceramide catabolic process(GO:0006680) negative regulation of filopodium assembly(GO:0051490)
0.0 0.8 GO:0035914 skeletal muscle cell differentiation(GO:0035914)
0.2 0.7 GO:0003150 muscular septum morphogenesis(GO:0003150)
0.1 0.7 GO:0061642 chemoattraction of axon(GO:0061642)
0.1 0.7 GO:0048852 diencephalon morphogenesis(GO:0048852)
0.1 0.7 GO:0030322 stabilization of membrane potential(GO:0030322)
0.0 0.7 GO:0030513 positive regulation of BMP signaling pathway(GO:0030513)
0.0 0.7 GO:0060351 cartilage development involved in endochondral bone morphogenesis(GO:0060351)
0.1 0.6 GO:0001842 neural fold formation(GO:0001842)
0.1 0.6 GO:0060272 embryonic skeletal joint morphogenesis(GO:0060272)
0.2 0.5 GO:0003195 tricuspid valve development(GO:0003175) tricuspid valve morphogenesis(GO:0003186) tricuspid valve formation(GO:0003195) right ventricular cardiac muscle tissue morphogenesis(GO:0003221)
0.1 0.5 GO:0060022 hard palate development(GO:0060022)
0.1 0.5 GO:1901204 positive regulation of guanylate cyclase activity(GO:0031284) regulation of adrenergic receptor signaling pathway involved in heart process(GO:1901204)
0.1 0.5 GO:0033563 dorsal/ventral axon guidance(GO:0033563)
0.0 0.5 GO:0033234 negative regulation of protein sumoylation(GO:0033234)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 48 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 1.3 GO:0060170 ciliary membrane(GO:0060170)
0.0 1.0 GO:0097440 apical dendrite(GO:0097440)
0.1 0.9 GO:0000145 exocyst(GO:0000145)
0.2 0.7 GO:0060187 cell pole(GO:0060187)
0.1 0.7 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.0 0.7 GO:0045334 clathrin-coated endocytic vesicle(GO:0045334)
0.1 0.5 GO:0002111 BRCA2-BRAF35 complex(GO:0002111)
0.1 0.5 GO:0090537 CERF complex(GO:0090537)
0.1 0.5 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.0 0.5 GO:0042582 primary lysosome(GO:0005766) azurophil granule(GO:0042582)
0.0 0.5 GO:0035371 microtubule plus-end(GO:0035371)
0.1 0.4 GO:0005588 collagen type V trimer(GO:0005588)
0.0 0.4 GO:0031105 septin complex(GO:0031105)
0.0 0.4 GO:0042101 T cell receptor complex(GO:0042101)
0.0 0.4 GO:0016235 aggresome(GO:0016235)
0.1 0.3 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.0 0.3 GO:0090571 RNA polymerase II transcription repressor complex(GO:0090571)
0.0 0.3 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
0.0 0.3 GO:0031209 SCAR complex(GO:0031209)
0.0 0.3 GO:0032580 Golgi cisterna membrane(GO:0032580)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 98 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.5 1.5 GO:0004994 somatostatin receptor activity(GO:0004994)
0.0 1.0 GO:0017049 GTP-Rho binding(GO:0017049)
0.2 0.8 GO:0070976 calcium-independent protein kinase C activity(GO:0004699) TIR domain binding(GO:0070976)
0.1 0.8 GO:0048406 nerve growth factor binding(GO:0048406)
0.2 0.7 GO:1902379 chemoattractant activity involved in axon guidance(GO:1902379)
0.1 0.7 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.1 0.6 GO:0048495 Roundabout binding(GO:0048495)
0.1 0.6 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.2 0.5 GO:0004517 nitric-oxide synthase activity(GO:0004517)
0.1 0.5 GO:0097016 L27 domain binding(GO:0097016)
0.0 0.5 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.5 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.1 0.4 GO:0050510 N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
0.1 0.4 GO:0004921 interleukin-11 receptor activity(GO:0004921) interleukin-11 binding(GO:0019970)
0.1 0.4 GO:0008269 JAK pathway signal transduction adaptor activity(GO:0008269)
0.0 0.4 GO:0030550 acetylcholine receptor inhibitor activity(GO:0030550)
0.0 0.4 GO:0015187 glycine transmembrane transporter activity(GO:0015187)
0.0 0.4 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.0 0.4 GO:0005227 calcium activated cation channel activity(GO:0005227)
0.1 0.3 GO:0047844 deoxycytidine deaminase activity(GO:0047844)