Motif ID: Plagl1

Z-value: 0.532


Transcription factors associated with Plagl1:

Gene SymbolEntrez IDGene Name
Plagl1 ENSMUSG00000019817.12 Plagl1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Plagl1mm10_v2_chr10_+_13090788_13090843-0.342.3e-01Click!


Activity profile for motif Plagl1.

activity profile for motif Plagl1


Sorted Z-values histogram for motif Plagl1

Sorted Z-values for motif Plagl1



Network of associatons between targets according to the STRING database.



First level regulatory network of Plagl1

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr4_+_47288287 0.792 ENSMUST00000146967.1
 Col15a1
collagen, type XV, alpha 1
chr13_+_104229366 0.546 ENSMUST00000022227.6
 Cenpk
centromere protein K
chr4_+_47288057 0.537 ENSMUST00000140413.1
ENSMUST00000107731.2
 Col15a1

collagen, type XV, alpha 1

chr1_-_88205674 0.432 ENSMUST00000119972.2
 Dnajb3
DnaJ (Hsp40) homolog, subfamily B, member 3
chr18_-_38601268 0.426 ENSMUST00000025295.6
 Spry4
sprouty homolog 4 (Drosophila)
chr1_-_120074023 0.391 ENSMUST00000056089.7
 Tmem37
transmembrane protein 37
chr14_-_54864055 0.382 ENSMUST00000142283.2
 Homez
homeodomain leucine zipper-encoding gene
chr9_+_75625707 0.376 ENSMUST00000034702.4
 Lysmd2
LysM, putative peptidoglycan-binding, domain containing 2
chr5_-_136567242 0.371 ENSMUST00000175975.2
ENSMUST00000176216.2
ENSMUST00000176745.1
 Cux1


cut-like homeobox 1


chr6_+_4504814 0.357 ENSMUST00000141483.1
 Col1a2
collagen, type I, alpha 2
chr12_-_103443653 0.355 ENSMUST00000055071.8
 Ifi27l2a
interferon, alpha-inducible protein 27 like 2A
chr4_-_139092958 0.353 ENSMUST00000042844.6
 Nbl1
neuroblastoma, suppression of tumorigenicity 1
chr5_-_136883115 0.347 ENSMUST00000057497.6
ENSMUST00000111103.1
 Col26a1

collagen, type XXVI, alpha 1

chr6_+_110645572 0.339 ENSMUST00000071076.6
ENSMUST00000172951.1
 Grm7

glutamate receptor, metabotropic 7

chr7_-_4515959 0.319 ENSMUST00000163710.1
ENSMUST00000166268.1
ENSMUST00000071798.6
ENSMUST00000178163.1
ENSMUST00000108587.2
 Tnnt1




troponin T1, skeletal, slow




chr17_-_24644933 0.317 ENSMUST00000019684.5
 Slc9a3r2
solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 2
chr4_+_148160613 0.297 ENSMUST00000047951.8
 Fbxo2
F-box protein 2
chr15_-_82244716 0.294 ENSMUST00000089155.4
ENSMUST00000089157.3
 Cenpm

centromere protein M

chr5_-_139130159 0.290 ENSMUST00000129851.1
 Prkar1b
protein kinase, cAMP dependent regulatory, type I beta
chr6_-_91807318 0.271 ENSMUST00000159684.1
 Grip2
glutamate receptor interacting protein 2
chrX_-_37085402 0.211 ENSMUST00000115231.3
 Rpl39
ribosomal protein L39
chr6_-_128143525 0.200 ENSMUST00000032503.5
ENSMUST00000112173.1
 Tspan9

tetraspanin 9

chr6_-_128438673 0.191 ENSMUST00000032508.4
 Fkbp4
FK506 binding protein 4
chr4_+_152338619 0.189 ENSMUST00000030775.5
ENSMUST00000164662.1
 Chd5

chromodomain helicase DNA binding protein 5

chr11_+_98741871 0.185 ENSMUST00000103139.4
 Thra
thyroid hormone receptor alpha
chr15_+_75993756 0.184 ENSMUST00000089669.4
 Mapk15
mitogen-activated protein kinase 15
chr19_+_6497772 0.177 ENSMUST00000113458.1
ENSMUST00000113459.1
 Nrxn2

neurexin II

chr5_+_125475814 0.171 ENSMUST00000031445.3
 Aacs
acetoacetyl-CoA synthetase
chr1_+_74588347 0.165 ENSMUST00000113732.1
 Bcs1l
BCS1-like (yeast)
chr16_+_32099781 0.165 ENSMUST00000115168.2
 Cep19
centrosomal protein 19
chr12_+_3891728 0.163 ENSMUST00000172689.1
ENSMUST00000111186.1
 Dnmt3a

DNA methyltransferase 3A

chr6_-_128200598 0.162 ENSMUST00000071101.6
 Gm10010
predicted gene 10010
chr8_-_25101985 0.159 ENSMUST00000128715.1
ENSMUST00000064883.6
 Plekha2

pleckstrin homology domain-containing, family A (phosphoinositide binding specific) member 2

chr17_+_46297406 0.159 ENSMUST00000061722.6
ENSMUST00000166280.1
 Dlk2

delta-like 2 homolog (Drosophila)

chr17_+_29660710 0.156 ENSMUST00000130423.1
 Cmtr1
cap methyltransferase 1
chr6_+_40325471 0.155 ENSMUST00000031977.8
 Agk
acylglycerol kinase
chr2_+_174076296 0.153 ENSMUST00000155000.1
ENSMUST00000134876.1
ENSMUST00000147038.1
 Stx16


syntaxin 16


chr11_+_32455362 0.153 ENSMUST00000051053.4
 Ubtd2
ubiquitin domain containing 2
chr13_+_104228929 0.153 ENSMUST00000070761.3
 Cenpk
centromere protein K
chr4_+_129136948 0.149 ENSMUST00000102600.3
 Fndc5
fibronectin type III domain containing 5
chr13_+_5861489 0.147 ENSMUST00000000080.6
 Klf6
Kruppel-like factor 6
chrX_+_99821021 0.144 ENSMUST00000096363.2
 Tmem28
transmembrane protein 28
chr1_+_74588289 0.142 ENSMUST00000113733.3
ENSMUST00000027358.4
 Bcs1l

BCS1-like (yeast)

chr11_+_67966442 0.141 ENSMUST00000021286.4
ENSMUST00000108675.1
 Stx8

syntaxin 8

chr11_+_98741805 0.139 ENSMUST00000064187.5
 Thra
thyroid hormone receptor alpha
chr16_+_32099904 0.136 ENSMUST00000042869.6
 Cep19
centrosomal protein 19
chr11_-_120047144 0.135 ENSMUST00000103020.1
 Aatk
apoptosis-associated tyrosine kinase
chr7_+_142533012 0.135 ENSMUST00000038675.6
 Mrpl23
mitochondrial ribosomal protein L23
chr4_+_106561027 0.135 ENSMUST00000047973.3
 Dhcr24
24-dehydrocholesterol reductase
chr6_-_91807424 0.135 ENSMUST00000162300.1
 Grip2
glutamate receptor interacting protein 2
chr16_-_19706365 0.130 ENSMUST00000081880.5
 Lamp3
lysosomal-associated membrane protein 3
chr17_+_46297917 0.130 ENSMUST00000166617.1
ENSMUST00000170271.1
 Dlk2

delta-like 2 homolog (Drosophila)

chr17_+_35126316 0.125 ENSMUST00000061859.6
 D17H6S53E
DNA segment, Chr 17, human D6S53E
chr5_-_122264378 0.124 ENSMUST00000111738.3
 Tctn1
tectonic family member 1
chr2_-_18998126 0.123 ENSMUST00000006912.5
 Pip4k2a
phosphatidylinositol-5-phosphate 4-kinase, type II, alpha
chr12_-_15816762 0.113 ENSMUST00000020922.7
 Trib2
tribbles homolog 2 (Drosophila)
chr19_+_5474681 0.110 ENSMUST00000165485.1
ENSMUST00000166253.1
ENSMUST00000167371.1
ENSMUST00000167855.1
ENSMUST00000070118.7
 Efemp2




epidermal growth factor-containing fibulin-like extracellular matrix protein 2




chr2_-_130642770 0.107 ENSMUST00000045761.6
 Lzts3
leucine zipper, putative tumor suppressor family member 3
chr16_-_34262830 0.106 ENSMUST00000114947.1
 Kalrn
kalirin, RhoGEF kinase
chr4_+_155249960 0.106 ENSMUST00000178473.1
ENSMUST00000105627.1
ENSMUST00000097747.2
 2610002J02Rik


RIKEN cDNA 2610002J02 gene


chr11_+_70018421 0.102 ENSMUST00000108588.1
 Dlg4
discs, large homolog 4 (Drosophila)
chr5_-_24577467 0.101 ENSMUST00000030795.8
 Abcf2
ATP-binding cassette, sub-family F (GCN20), member 2
chr9_+_62342449 0.101 ENSMUST00000156461.1
 Anp32a
acidic (leucine-rich) nuclear phosphoprotein 32 family, member A
chr7_+_45872772 0.099 ENSMUST00000002855.5
ENSMUST00000107719.1
 Kdelr1

KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1

chr2_-_3419066 0.098 ENSMUST00000115082.3
 Meig1
meiosis expressed gene 1
chr12_+_100199435 0.094 ENSMUST00000110082.3
 Calm1
calmodulin 1
chr2_-_104257400 0.093 ENSMUST00000141159.1
 D430041D05Rik
RIKEN cDNA D430041D05 gene
chr10_-_70599284 0.088 ENSMUST00000046513.3
 Phyhipl
phytanoyl-CoA hydroxylase interacting protein-like
chr17_+_29549783 0.088 ENSMUST00000048677.7
 Tbc1d22b
TBC1 domain family, member 22B
chr17_-_25868727 0.085 ENSMUST00000026828.5
 Fam195a
family with sequence similarity 195, member A
chrX_+_20870166 0.078 ENSMUST00000115342.3
ENSMUST00000009530.4
 Timp1

tissue inhibitor of metalloproteinase 1

chr10_+_38965515 0.076 ENSMUST00000019992.5
 Lama4
laminin, alpha 4
chr15_-_52478228 0.075 ENSMUST00000081993.1
 Gm10020
predicted pseudogene 10020
chr9_+_108662098 0.075 ENSMUST00000035222.5
 Slc25a20
solute carrier family 25 (mitochondrial carnitine/acylcarnitine translocase), member 20
chr16_-_32099697 0.074 ENSMUST00000155966.1
ENSMUST00000096109.4
 Pigx

phosphatidylinositol glycan anchor biosynthesis, class X

chr6_+_128438757 0.071 ENSMUST00000144745.1
 Gm10069
predicted gene 10069
chr1_-_74587964 0.065 ENSMUST00000027315.7
ENSMUST00000113737.1
 Zfp142

zinc finger protein 142

chr19_-_4625612 0.058 ENSMUST00000025823.3
 Rce1
RCE1 homolog, prenyl protein peptidase (S. cerevisiae)
chrX_-_73824938 0.052 ENSMUST00000114438.2
ENSMUST00000002080.5
 Pdzd4

PDZ domain containing 4

chr10_+_128377086 0.051 ENSMUST00000014642.3
 Ankrd52
ankyrin repeat domain 52
chr8_+_93810832 0.049 ENSMUST00000034198.8
ENSMUST00000125716.1
 Gnao1

guanine nucleotide binding protein, alpha O

chr7_-_118995211 0.049 ENSMUST00000008878.8
 Gprc5b
G protein-coupled receptor, family C, group 5, member B
chr15_-_99251929 0.048 ENSMUST00000041190.9
ENSMUST00000163506.1
 Mcrs1

microspherule protein 1

chr2_-_152332639 0.048 ENSMUST00000028964.7
 Rbck1
RanBP-type and C3HC4-type zinc finger containing 1
chr9_+_62342059 0.046 ENSMUST00000135395.1
 Anp32a
acidic (leucine-rich) nuclear phosphoprotein 32 family, member A
chr10_+_80016901 0.044 ENSMUST00000105373.1
 Hmha1
histocompatibility (minor) HA-1
chr6_-_48086530 0.043 ENSMUST00000073124.6
 Zfp746
zinc finger protein 746
chr1_-_128103016 0.043 ENSMUST00000097597.2
 Zranb3
zinc finger, RAN-binding domain containing 3
chr5_-_123012874 0.041 ENSMUST00000172729.1
 Kdm2b
lysine (K)-specific demethylase 2B
chr6_-_134887783 0.036 ENSMUST00000066107.6
 Gpr19
G protein-coupled receptor 19
chr1_+_134455524 0.033 ENSMUST00000112232.1
ENSMUST00000027725.4
ENSMUST00000116528.1
 Klhl12


kelch-like 12


chr3_+_124321031 0.031 ENSMUST00000058994.4
 Tram1l1
translocation associated membrane protein 1-like 1
chr17_-_35115428 0.031 ENSMUST00000172854.1
ENSMUST00000062657.4
 Ly6g5b

lymphocyte antigen 6 complex, locus G5B

chr6_-_124712131 0.029 ENSMUST00000004379.5
 Emg1
EMG1 nucleolar protein homolog (S. cerevisiae)
chr17_+_34593388 0.028 ENSMUST00000174532.1
 Pbx2
pre B cell leukemia homeobox 2
chr5_+_119834663 0.028 ENSMUST00000018407.6
 Tbx5
T-box 5
chr17_-_25274299 0.028 ENSMUST00000172587.1
ENSMUST00000049911.9
ENSMUST00000173713.1
 Ube2i


ubiquitin-conjugating enzyme E2I


chr13_+_74350313 0.028 ENSMUST00000160021.1
ENSMUST00000162672.1
ENSMUST00000162376.1
 Ccdc127


coiled-coil domain containing 127


chr1_-_128102412 0.027 ENSMUST00000112538.1
ENSMUST00000086614.5
 Zranb3

zinc finger, RAN-binding domain containing 3

chr5_-_92083667 0.027 ENSMUST00000113127.3
 G3bp2
GTPase activating protein (SH3 domain) binding protein 2
chr10_-_128547722 0.026 ENSMUST00000040572.3
 Zc3h10
zinc finger CCCH type containing 10
chr10_-_76961788 0.026 ENSMUST00000001148.4
ENSMUST00000105411.2
 Pcbp3

poly(rC) binding protein 3

chr6_-_92481343 0.025 ENSMUST00000113445.1
 Prickle2
prickle homolog 2 (Drosophila)
chr18_+_32377176 0.025 ENSMUST00000091967.5
ENSMUST00000025239.7
 Bin1

bridging integrator 1

chr5_-_143269958 0.024 ENSMUST00000161448.1
 Zfp316
zinc finger protein 316
chr17_+_29032664 0.024 ENSMUST00000130216.1
 Srsf3
serine/arginine-rich splicing factor 3
chr11_+_87699897 0.022 ENSMUST00000040089.4
 Rnf43
ring finger protein 43
chr1_-_179546261 0.021 ENSMUST00000027769.5
 Tfb2m
transcription factor B2, mitochondrial
chr17_+_25016343 0.020 ENSMUST00000024983.5
 Ift140
intraflagellar transport 140
chr9_+_46273064 0.013 ENSMUST00000156440.1
ENSMUST00000034583.6
ENSMUST00000114552.3
 Zfp259


zinc finger protein 259


chr7_+_5015466 0.012 ENSMUST00000086349.3
 Zfp524
zinc finger protein 524
chr2_-_132145057 0.010 ENSMUST00000028815.8
 Slc23a2
solute carrier family 23 (nucleobase transporters), member 2
chr9_+_106453838 0.009 ENSMUST00000024260.6
 Pcbp4
poly(rC) binding protein 4
chr1_+_179546303 0.009 ENSMUST00000040706.8
 Cnst
consortin, connexin sorting protein
chr11_+_95010277 0.008 ENSMUST00000124735.1
 Samd14
sterile alpha motif domain containing 14
chr1_-_5019342 0.008 ENSMUST00000002533.8
 Rgs20
regulator of G-protein signaling 20
chr9_+_64960892 0.007 ENSMUST00000037504.5
 Vwa9
von Willebrand factor A domain containing 9
chr5_-_92083455 0.006 ENSMUST00000169094.1
ENSMUST00000167918.1
 G3bp2

GTPase activating protein (SH3 domain) binding protein 2

chr12_+_110889231 0.006 ENSMUST00000169597.1
ENSMUST00000165978.1
 Tecpr2

tectonin beta-propeller repeat containing 2

chr17_-_84682932 0.005 ENSMUST00000066175.3
 Abcg5
ATP-binding cassette, sub-family G (WHITE), member 5
chr9_+_72806874 0.004 ENSMUST00000055535.8
 Prtg
protogenin homolog (Gallus gallus)
chr11_+_53519871 0.004 ENSMUST00000120878.2
 Sept8
septin 8
chr7_-_99695809 0.002 ENSMUST00000107086.2
 Slco2b1
solute carrier organic anion transporter family, member 2b1

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0035582 sequestering of BMP in extracellular matrix(GO:0035582)
0.1 0.3 GO:0017055 negative regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0017055)
0.1 0.3 GO:0001661 conditioned taste aversion(GO:0001661)
0.1 0.2 GO:0097309 cap1 mRNA methylation(GO:0097309)
0.0 0.4 GO:0014824 artery smooth muscle contraction(GO:0014824)
0.0 0.2 GO:0035093 spermatogenesis, exchange of chromosomal proteins(GO:0035093)
0.0 0.3 GO:0034551 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033)
0.0 0.3 GO:0014883 transition between fast and slow fiber(GO:0014883)
0.0 0.4 GO:0043589 skin morphogenesis(GO:0043589)
0.0 0.3 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.0 0.1 GO:0036292 DNA rewinding(GO:0036292)
0.0 0.1 GO:0090336 positive regulation of brown fat cell differentiation(GO:0090336)
0.0 0.1 GO:1904491 protein localization to ciliary transition zone(GO:1904491)
0.0 0.2 GO:0044027 hypermethylation of CpG island(GO:0044027)
0.0 0.2 GO:0002227 innate immune response in mucosa(GO:0002227)
0.0 0.3 GO:0006516 glycoprotein catabolic process(GO:0006516)
0.0 0.1 GO:0051045 negative regulation of membrane protein ectodomain proteolysis(GO:0051045) negative regulation of trophoblast cell migration(GO:1901164)
0.0 0.1 GO:0031639 plasminogen activation(GO:0031639)
0.0 0.1 GO:0006621 protein retention in ER lumen(GO:0006621)
0.0 0.1 GO:2000786 positive regulation of autophagosome assembly(GO:2000786)
0.0 0.1 GO:0061368 behavioral response to chemical pain(GO:0061366) behavioral response to formalin induced pain(GO:0061368)
0.0 0.2 GO:0014067 negative regulation of phosphatidylinositol 3-kinase signaling(GO:0014067)
0.0 0.1 GO:0032482 Rab protein signal transduction(GO:0032482)
0.0 0.0 GO:1904749 regulation of protein localization to nucleolus(GO:1904749) positive regulation of protein localization to nucleolus(GO:1904751)
0.0 0.0 GO:0048208 vesicle targeting, rough ER to cis-Golgi(GO:0048207) COPII vesicle coating(GO:0048208)
0.0 0.1 GO:0032693 negative regulation of interleukin-10 production(GO:0032693)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0005584 collagen type I trimer(GO:0005584)
0.1 0.3 GO:0005861 troponin complex(GO:0005861)
0.1 0.3 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.0 0.1 GO:0097233 lamellar body membrane(GO:0097232) alveolar lamellar body membrane(GO:0097233)
0.0 0.2 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.0 1.7 GO:0005581 collagen trimer(GO:0005581)
0.0 0.3 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 0.0 GO:0071797 LUBAC complex(GO:0071797)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0016015 morphogen activity(GO:0016015)
0.1 0.3 GO:0070905 serine binding(GO:0070905)
0.1 0.3 GO:0002153 steroid receptor RNA activator RNA binding(GO:0002153)
0.1 0.3 GO:0031014 troponin T binding(GO:0031014)
0.0 0.2 GO:0047760 butyrate-CoA ligase activity(GO:0047760)
0.0 0.1 GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.0 0.2 GO:0004483 mRNA (nucleoside-2'-O-)-methyltransferase activity(GO:0004483)
0.0 0.2 GO:0032767 copper-dependent protein binding(GO:0032767)
0.0 0.3 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.0 0.1 GO:0046923 ER retention sequence binding(GO:0046923)
0.0 0.4 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.0 0.1 GO:0031800 type 3 metabotropic glutamate receptor binding(GO:0031800)
0.0 0.2 GO:0051718 DNA (cytosine-5-)-methyltransferase activity(GO:0003886) DNA (cytosine-5-)-methyltransferase activity, acting on CpG substrates(GO:0051718)
0.0 0.1 GO:0019869 chloride channel inhibitor activity(GO:0019869)
0.0 0.2 GO:0001727 lipid kinase activity(GO:0001727)
0.0 0.3 GO:0050750 low-density lipoprotein particle receptor binding(GO:0050750)
0.0 0.1 GO:0031811 G-protein coupled nucleotide receptor binding(GO:0031811) P2Y1 nucleotide receptor binding(GO:0031812)
0.0 0.0 GO:1990825 sequence-specific mRNA binding(GO:1990825)
0.0 0.1 GO:0015651 quaternary ammonium group transmembrane transporter activity(GO:0015651)