Motif ID: Plagl1

Z-value: 0.532


Transcription factors associated with Plagl1:

Gene SymbolEntrez IDGene Name
Plagl1 ENSMUSG00000019817.12 Plagl1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Plagl1mm10_v2_chr10_+_13090788_13090843-0.342.3e-01Click!


Activity profile for motif Plagl1.

activity profile for motif Plagl1


Sorted Z-values histogram for motif Plagl1

Sorted Z-values for motif Plagl1



Network of associatons between targets according to the STRING database.



First level regulatory network of Plagl1

PNG image of the network

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Top targets:


Showing 1 to 20 of 123 entries
PromoterScoreRefseqGene SymbolGene Name
chr4_+_47288287 0.792 ENSMUST00000146967.1
 Col15a1
collagen, type XV, alpha 1
chr13_+_104229366 0.546 ENSMUST00000022227.6
 Cenpk
centromere protein K
chr4_+_47288057 0.537 ENSMUST00000140413.1
ENSMUST00000107731.2
 Col15a1

collagen, type XV, alpha 1

chr1_-_88205674 0.432 ENSMUST00000119972.2
 Dnajb3
DnaJ (Hsp40) homolog, subfamily B, member 3
chr18_-_38601268 0.426 ENSMUST00000025295.6
 Spry4
sprouty homolog 4 (Drosophila)
chr1_-_120074023 0.391 ENSMUST00000056089.7
 Tmem37
transmembrane protein 37
chr14_-_54864055 0.382 ENSMUST00000142283.2
 Homez
homeodomain leucine zipper-encoding gene
chr9_+_75625707 0.376 ENSMUST00000034702.4
 Lysmd2
LysM, putative peptidoglycan-binding, domain containing 2
chr5_-_136567242 0.371 ENSMUST00000175975.2
ENSMUST00000176216.2
ENSMUST00000176745.1
 Cux1


cut-like homeobox 1


chr6_+_4504814 0.357 ENSMUST00000141483.1
 Col1a2
collagen, type I, alpha 2
chr12_-_103443653 0.355 ENSMUST00000055071.8
 Ifi27l2a
interferon, alpha-inducible protein 27 like 2A
chr4_-_139092958 0.353 ENSMUST00000042844.6
 Nbl1
neuroblastoma, suppression of tumorigenicity 1
chr5_-_136883115 0.347 ENSMUST00000057497.6
ENSMUST00000111103.1
 Col26a1

collagen, type XXVI, alpha 1

chr6_+_110645572 0.339 ENSMUST00000071076.6
ENSMUST00000172951.1
 Grm7

glutamate receptor, metabotropic 7

chr7_-_4515959 0.319 ENSMUST00000163710.1
ENSMUST00000166268.1
ENSMUST00000071798.6
ENSMUST00000178163.1
ENSMUST00000108587.2
 Tnnt1




troponin T1, skeletal, slow




chr17_-_24644933 0.317 ENSMUST00000019684.5
 Slc9a3r2
solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 2
chr4_+_148160613 0.297 ENSMUST00000047951.8
 Fbxo2
F-box protein 2
chr15_-_82244716 0.294 ENSMUST00000089155.4
ENSMUST00000089157.3
 Cenpm

centromere protein M

chr5_-_139130159 0.290 ENSMUST00000129851.1
 Prkar1b
protein kinase, cAMP dependent regulatory, type I beta
chr6_-_91807318 0.271 ENSMUST00000159684.1
 Grip2
glutamate receptor interacting protein 2

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 26 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 0.4 GO:0035582 sequestering of BMP in extracellular matrix(GO:0035582)
0.0 0.4 GO:0014824 artery smooth muscle contraction(GO:0014824)
0.0 0.4 GO:0043589 skin morphogenesis(GO:0043589)
0.1 0.3 GO:0017055 negative regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0017055)
0.1 0.3 GO:0001661 conditioned taste aversion(GO:0001661)
0.0 0.3 GO:0034551 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033)
0.0 0.3 GO:0014883 transition between fast and slow fiber(GO:0014883)
0.0 0.3 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.0 0.3 GO:0006516 glycoprotein catabolic process(GO:0006516)
0.1 0.2 GO:0097309 cap1 mRNA methylation(GO:0097309)
0.0 0.2 GO:0035093 spermatogenesis, exchange of chromosomal proteins(GO:0035093)
0.0 0.2 GO:0044027 hypermethylation of CpG island(GO:0044027)
0.0 0.2 GO:0002227 innate immune response in mucosa(GO:0002227)
0.0 0.2 GO:0014067 negative regulation of phosphatidylinositol 3-kinase signaling(GO:0014067)
0.0 0.1 GO:0036292 DNA rewinding(GO:0036292)
0.0 0.1 GO:0090336 positive regulation of brown fat cell differentiation(GO:0090336)
0.0 0.1 GO:1904491 protein localization to ciliary transition zone(GO:1904491)
0.0 0.1 GO:0051045 negative regulation of membrane protein ectodomain proteolysis(GO:0051045) negative regulation of trophoblast cell migration(GO:1901164)
0.0 0.1 GO:0031639 plasminogen activation(GO:0031639)
0.0 0.1 GO:0006621 protein retention in ER lumen(GO:0006621)

Gene overrepresentation in cellular_component category:

Showing 1 to 8 of 8 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 1.7 GO:0005581 collagen trimer(GO:0005581)
0.1 0.4 GO:0005584 collagen type I trimer(GO:0005584)
0.1 0.3 GO:0005861 troponin complex(GO:0005861)
0.1 0.3 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.0 0.3 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 0.2 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.0 0.1 GO:0097233 lamellar body membrane(GO:0097232) alveolar lamellar body membrane(GO:0097233)
0.0 0.0 GO:0071797 LUBAC complex(GO:0071797)

Gene overrepresentation in molecular_function category:

Showing 1 to 19 of 19 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 0.4 GO:0016015 morphogen activity(GO:0016015)
0.0 0.4 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.1 0.3 GO:0070905 serine binding(GO:0070905)
0.1 0.3 GO:0002153 steroid receptor RNA activator RNA binding(GO:0002153)
0.1 0.3 GO:0031014 troponin T binding(GO:0031014)
0.0 0.3 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.0 0.3 GO:0050750 low-density lipoprotein particle receptor binding(GO:0050750)
0.0 0.2 GO:0047760 butyrate-CoA ligase activity(GO:0047760)
0.0 0.2 GO:0004483 mRNA (nucleoside-2'-O-)-methyltransferase activity(GO:0004483)
0.0 0.2 GO:0032767 copper-dependent protein binding(GO:0032767)
0.0 0.2 GO:0051718 DNA (cytosine-5-)-methyltransferase activity(GO:0003886) DNA (cytosine-5-)-methyltransferase activity, acting on CpG substrates(GO:0051718)
0.0 0.2 GO:0001727 lipid kinase activity(GO:0001727)
0.0 0.1 GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.0 0.1 GO:0046923 ER retention sequence binding(GO:0046923)
0.0 0.1 GO:0031800 type 3 metabotropic glutamate receptor binding(GO:0031800)
0.0 0.1 GO:0019869 chloride channel inhibitor activity(GO:0019869)
0.0 0.1 GO:0031811 G-protein coupled nucleotide receptor binding(GO:0031811) P2Y1 nucleotide receptor binding(GO:0031812)
0.0 0.1 GO:0015651 quaternary ammonium group transmembrane transporter activity(GO:0015651)
0.0 0.0 GO:1990825 sequence-specific mRNA binding(GO:1990825)