Motif ID: Pou2f1
Z-value: 1.409
Transcription factors associated with Pou2f1:
| Gene Symbol | Entrez ID | Gene Name |
|---|---|---|
| Pou2f1 | ENSMUSG00000026565.12 | Pou2f1 |
Activity-expression correlation:
| Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| Pou2f1 | mm10_v2_chr1_-_165934900_165935036 | 0.24 | 4.2e-01 | Click! |
Top targets:
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.6 | 2.3 | GO:1903378 | positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903378) |
| 0.5 | 1.5 | GO:0007521 | muscle cell fate determination(GO:0007521) cellular response to parathyroid hormone stimulus(GO:0071374) positive regulation of macrophage apoptotic process(GO:2000111) |
| 0.4 | 2.8 | GO:1901162 | tryptophan metabolic process(GO:0006568) indolalkylamine metabolic process(GO:0006586) serotonin biosynthetic process(GO:0042427) primary amino compound biosynthetic process(GO:1901162) |
| 0.4 | 1.2 | GO:0051464 | positive regulation of cortisol secretion(GO:0051464) |
| 0.4 | 1.1 | GO:0035701 | hematopoietic stem cell migration(GO:0035701) |
| 0.3 | 1.0 | GO:0030210 | heparin biosynthetic process(GO:0030210) Tie signaling pathway(GO:0048014) |
| 0.3 | 7.6 | GO:0010614 | negative regulation of cardiac muscle hypertrophy(GO:0010614) |
| 0.3 | 0.9 | GO:0046110 | xanthine metabolic process(GO:0046110) |
| 0.3 | 0.9 | GO:0046544 | development of secondary male sexual characteristics(GO:0046544) |
| 0.3 | 1.6 | GO:0035743 | CD4-positive, alpha-beta T cell cytokine production(GO:0035743) T-helper 2 cell cytokine production(GO:0035745) |
| 0.3 | 0.8 | GO:1901421 | positive regulation of response to alcohol(GO:1901421) |
| 0.2 | 0.7 | GO:0050929 | corticospinal neuron axon guidance through spinal cord(GO:0021972) positive regulation of negative chemotaxis(GO:0050924) induction of negative chemotaxis(GO:0050929) negative regulation of mononuclear cell migration(GO:0071676) negative regulation of retinal ganglion cell axon guidance(GO:0090260) |
| 0.2 | 0.9 | GO:0019287 | isopentenyl diphosphate biosynthetic process(GO:0009240) isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287) isopentenyl diphosphate metabolic process(GO:0046490) |
| 0.2 | 1.2 | GO:0003065 | positive regulation of heart rate by epinephrine(GO:0003065) |
| 0.2 | 1.0 | GO:0015788 | UDP-N-acetylglucosamine transport(GO:0015788) |
| 0.2 | 1.8 | GO:0030854 | positive regulation of granulocyte differentiation(GO:0030854) |
| 0.2 | 1.1 | GO:0015015 | heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015) |
| 0.2 | 0.5 | GO:2001187 | positive regulation of CD8-positive, alpha-beta T cell activation(GO:2001187) |
| 0.2 | 0.8 | GO:0042270 | protection from natural killer cell mediated cytotoxicity(GO:0042270) |
| 0.1 | 0.3 | GO:0002314 | germinal center B cell differentiation(GO:0002314) |
| 0.1 | 0.4 | GO:0044778 | meiotic DNA integrity checkpoint(GO:0044778) |
| 0.1 | 1.1 | GO:0070314 | G1 to G0 transition(GO:0070314) |
| 0.1 | 1.1 | GO:0033353 | S-adenosylmethionine cycle(GO:0033353) |
| 0.1 | 1.2 | GO:0050957 | equilibrioception(GO:0050957) |
| 0.1 | 0.4 | GO:0009812 | flavonoid metabolic process(GO:0009812) flavonoid biosynthetic process(GO:0009813) flavonoid glucuronidation(GO:0052696) |
| 0.1 | 1.5 | GO:0051601 | exocyst localization(GO:0051601) |
| 0.1 | 2.6 | GO:0006883 | cellular sodium ion homeostasis(GO:0006883) |
| 0.1 | 2.2 | GO:0002495 | antigen processing and presentation of peptide antigen via MHC class II(GO:0002495) |
| 0.1 | 0.8 | GO:0045200 | establishment or maintenance of neuroblast polarity(GO:0045196) establishment of neuroblast polarity(GO:0045200) |
| 0.1 | 0.3 | GO:0043988 | histone H3-S28 phosphorylation(GO:0043988) |
| 0.1 | 0.5 | GO:2000343 | positive regulation of chemokine (C-X-C motif) ligand 2 production(GO:2000343) |
| 0.1 | 0.3 | GO:1904431 | positive regulation of t-circle formation(GO:1904431) |
| 0.1 | 6.0 | GO:0008542 | visual learning(GO:0008542) |
| 0.1 | 0.5 | GO:2000298 | regulation of Rho-dependent protein serine/threonine kinase activity(GO:2000298) |
| 0.1 | 1.1 | GO:0014807 | regulation of somitogenesis(GO:0014807) |
| 0.1 | 0.5 | GO:0010359 | regulation of anion channel activity(GO:0010359) |
| 0.1 | 3.5 | GO:0033014 | porphyrin-containing compound biosynthetic process(GO:0006779) tetrapyrrole biosynthetic process(GO:0033014) |
| 0.1 | 0.6 | GO:0032196 | transposition(GO:0032196) |
| 0.1 | 0.5 | GO:1902261 | positive regulation of delayed rectifier potassium channel activity(GO:1902261) positive regulation of voltage-gated potassium channel activity(GO:1903818) |
| 0.1 | 0.2 | GO:0060025 | regulation of synaptic activity(GO:0060025) |
| 0.1 | 0.2 | GO:0090258 | negative regulation of mitochondrial fission(GO:0090258) |
| 0.1 | 0.3 | GO:0072592 | regulation of integrin biosynthetic process(GO:0045113) oxygen metabolic process(GO:0072592) |
| 0.1 | 0.2 | GO:1904192 | cholangiocyte apoptotic process(GO:1902488) regulation of cholangiocyte apoptotic process(GO:1904192) negative regulation of cholangiocyte apoptotic process(GO:1904193) |
| 0.1 | 0.7 | GO:2000051 | negative regulation of non-canonical Wnt signaling pathway(GO:2000051) |
| 0.1 | 0.6 | GO:0045899 | positive regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045899) |
| 0.1 | 0.2 | GO:0034310 | primary alcohol catabolic process(GO:0034310) |
| 0.1 | 0.3 | GO:0044375 | regulation of peroxisome size(GO:0044375) |
| 0.0 | 0.9 | GO:0045063 | T-helper 1 cell differentiation(GO:0045063) |
| 0.0 | 0.2 | GO:0034421 | post-translational protein acetylation(GO:0034421) |
| 0.0 | 1.3 | GO:0007638 | mechanosensory behavior(GO:0007638) |
| 0.0 | 1.1 | GO:0043552 | positive regulation of phosphatidylinositol 3-kinase activity(GO:0043552) |
| 0.0 | 0.2 | GO:0051593 | response to folic acid(GO:0051593) |
| 0.0 | 0.4 | GO:1902902 | negative regulation of autophagosome assembly(GO:1902902) |
| 0.0 | 0.5 | GO:0034244 | negative regulation of transcription elongation from RNA polymerase II promoter(GO:0034244) |
| 0.0 | 0.4 | GO:1901621 | negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:1901621) |
| 0.0 | 0.5 | GO:2000780 | negative regulation of double-strand break repair(GO:2000780) |
| 0.0 | 0.6 | GO:0071549 | cellular response to dexamethasone stimulus(GO:0071549) |
| 0.0 | 0.5 | GO:0042640 | anagen(GO:0042640) |
| 0.0 | 0.6 | GO:0007097 | nuclear migration(GO:0007097) |
| 0.0 | 0.1 | GO:1900864 | positive regulation of translational fidelity(GO:0045903) mitochondrial tRNA modification(GO:0070900) mitochondrial RNA modification(GO:1900864) |
| 0.0 | 0.1 | GO:0019478 | D-amino acid catabolic process(GO:0019478) |
| 0.0 | 0.3 | GO:0090557 | establishment of endothelial intestinal barrier(GO:0090557) |
| 0.0 | 0.1 | GO:0034196 | acylglycerol transport(GO:0034196) triglyceride transport(GO:0034197) |
| 0.0 | 0.1 | GO:1902512 | positive regulation of apoptotic DNA fragmentation(GO:1902512) positive regulation of DNA catabolic process(GO:1903626) |
| 0.0 | 0.1 | GO:0045908 | negative regulation of vasodilation(GO:0045908) |
| 0.0 | 0.5 | GO:0032011 | ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012) |
| 0.0 | 0.5 | GO:0006491 | N-glycan processing(GO:0006491) |
| 0.0 | 0.4 | GO:0006312 | mitotic recombination(GO:0006312) |
| 0.0 | 0.5 | GO:0043171 | peptide catabolic process(GO:0043171) |
| 0.0 | 1.1 | GO:0048477 | oogenesis(GO:0048477) |
| 0.0 | 0.2 | GO:0042523 | positive regulation of tyrosine phosphorylation of Stat5 protein(GO:0042523) |
| 0.0 | 0.2 | GO:0001516 | prostaglandin biosynthetic process(GO:0001516) prostanoid biosynthetic process(GO:0046457) |
| 0.0 | 0.2 | GO:0051988 | regulation of attachment of spindle microtubules to kinetochore(GO:0051988) |
| 0.0 | 0.4 | GO:0000266 | mitochondrial fission(GO:0000266) |
| 0.0 | 0.2 | GO:0030157 | pancreatic juice secretion(GO:0030157) |
| 0.0 | 0.2 | GO:0007095 | mitotic G2 DNA damage checkpoint(GO:0007095) |
| 0.0 | 0.0 | GO:1904742 | protein poly-ADP-ribosylation(GO:0070212) regulation of telomeric DNA binding(GO:1904742) |
| 0.0 | 0.3 | GO:0045540 | regulation of cholesterol biosynthetic process(GO:0045540) |
| 0.0 | 0.3 | GO:0030212 | hyaluronan metabolic process(GO:0030212) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.6 | 2.3 | GO:1990452 | Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452) |
| 0.5 | 3.2 | GO:0008091 | spectrin(GO:0008091) |
| 0.1 | 1.2 | GO:0005862 | muscle thin filament tropomyosin(GO:0005862) |
| 0.1 | 0.4 | GO:0071821 | FANCM-MHF complex(GO:0071821) |
| 0.1 | 0.5 | GO:0070022 | transforming growth factor beta receptor homodimeric complex(GO:0070022) |
| 0.1 | 0.5 | GO:0032021 | NELF complex(GO:0032021) |
| 0.1 | 1.5 | GO:0000145 | exocyst(GO:0000145) |
| 0.1 | 0.5 | GO:0000235 | astral microtubule(GO:0000235) |
| 0.1 | 7.6 | GO:0016605 | PML body(GO:0016605) |
| 0.1 | 2.2 | GO:0032588 | trans-Golgi network membrane(GO:0032588) |
| 0.1 | 0.4 | GO:0030896 | checkpoint clamp complex(GO:0030896) |
| 0.1 | 0.3 | GO:0032133 | chromosome passenger complex(GO:0032133) |
| 0.1 | 0.3 | GO:0071438 | NADPH oxidase complex(GO:0043020) invadopodium membrane(GO:0071438) |
| 0.1 | 0.6 | GO:0031595 | nuclear proteasome complex(GO:0031595) |
| 0.1 | 0.3 | GO:0048476 | Holliday junction resolvase complex(GO:0048476) |
| 0.1 | 0.2 | GO:0036454 | insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454) insulin-like growth factor ternary complex(GO:0042567) |
| 0.0 | 0.2 | GO:0097149 | centralspindlin complex(GO:0097149) |
| 0.0 | 0.2 | GO:0031618 | nuclear pericentric heterochromatin(GO:0031618) |
| 0.0 | 1.2 | GO:0030140 | trans-Golgi network transport vesicle(GO:0030140) |
| 0.0 | 0.4 | GO:0005641 | nuclear envelope lumen(GO:0005641) |
| 0.0 | 0.5 | GO:0042101 | T cell receptor complex(GO:0042101) |
| 0.0 | 0.4 | GO:0005952 | cAMP-dependent protein kinase complex(GO:0005952) |
| 0.0 | 5.6 | GO:0043679 | axon terminus(GO:0043679) |
| 0.0 | 0.5 | GO:0097228 | sperm principal piece(GO:0097228) |
| 0.0 | 0.5 | GO:0042470 | melanosome(GO:0042470) pigment granule(GO:0048770) |
| 0.0 | 0.5 | GO:0035861 | site of double-strand break(GO:0035861) |
| 0.0 | 0.3 | GO:0005640 | nuclear outer membrane(GO:0005640) |
| 0.0 | 2.9 | GO:0005770 | late endosome(GO:0005770) |
| 0.0 | 0.4 | GO:0005753 | mitochondrial proton-transporting ATP synthase complex(GO:0005753) |
| 0.0 | 0.2 | GO:0030867 | rough endoplasmic reticulum membrane(GO:0030867) |
| 0.0 | 0.1 | GO:0030289 | protein phosphatase 4 complex(GO:0030289) |
| 0.0 | 0.2 | GO:0031233 | intrinsic component of external side of plasma membrane(GO:0031233) |
| 0.0 | 0.4 | GO:0030992 | intraciliary transport particle B(GO:0030992) |
| 0.0 | 0.1 | GO:0035749 | myelin sheath adaxonal region(GO:0035749) |
| 0.0 | 0.3 | GO:0055038 | recycling endosome membrane(GO:0055038) |
| 0.0 | 0.3 | GO:0005779 | integral component of peroxisomal membrane(GO:0005779) |
| 0.0 | 2.4 | GO:0009897 | external side of plasma membrane(GO:0009897) |
| 0.0 | 0.2 | GO:0030126 | COPI vesicle coat(GO:0030126) |
| 0.0 | 0.8 | GO:0030864 | cortical actin cytoskeleton(GO:0030864) |
| 0.0 | 0.5 | GO:0031594 | neuromuscular junction(GO:0031594) |
| 0.0 | 1.0 | GO:0030175 | filopodium(GO:0030175) |
| 0.0 | 0.6 | GO:0005882 | intermediate filament(GO:0005882) |
| 0.0 | 2.7 | GO:0043235 | receptor complex(GO:0043235) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.9 | 2.8 | GO:0004510 | tryptophan 5-monooxygenase activity(GO:0004510) |
| 0.5 | 2.3 | GO:0050816 | phosphothreonine binding(GO:0050816) |
| 0.4 | 1.2 | GO:0004966 | galanin receptor activity(GO:0004966) |
| 0.4 | 1.1 | GO:0016494 | C-X-C chemokine receptor activity(GO:0016494) |
| 0.3 | 6.0 | GO:0005184 | neuropeptide hormone activity(GO:0005184) |
| 0.2 | 0.9 | GO:0030151 | molybdenum ion binding(GO:0030151) |
| 0.2 | 0.8 | GO:0008454 | alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454) |
| 0.2 | 1.1 | GO:0004013 | adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802) |
| 0.1 | 1.5 | GO:0003680 | AT DNA binding(GO:0003680) |
| 0.1 | 3.2 | GO:0030506 | ankyrin binding(GO:0030506) |
| 0.1 | 0.8 | GO:0046703 | natural killer cell lectin-like receptor binding(GO:0046703) |
| 0.1 | 0.3 | GO:0047598 | 7-dehydrocholesterol reductase activity(GO:0047598) |
| 0.1 | 2.2 | GO:0042287 | MHC protein binding(GO:0042287) |
| 0.1 | 0.7 | GO:0043237 | laminin-1 binding(GO:0043237) |
| 0.1 | 0.3 | GO:0035673 | oligopeptide transmembrane transporter activity(GO:0035673) |
| 0.1 | 0.5 | GO:0008865 | fructokinase activity(GO:0008865) mannokinase activity(GO:0019158) |
| 0.1 | 0.3 | GO:0030171 | voltage-gated proton channel activity(GO:0030171) |
| 0.1 | 0.6 | GO:0036402 | proteasome-activating ATPase activity(GO:0036402) |
| 0.1 | 0.3 | GO:0042030 | ATPase inhibitor activity(GO:0042030) angiostatin binding(GO:0043532) |
| 0.1 | 0.6 | GO:0001162 | RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding(GO:0001162) |
| 0.1 | 0.5 | GO:0015125 | bile acid transmembrane transporter activity(GO:0015125) |
| 0.1 | 1.0 | GO:0005172 | vascular endothelial growth factor receptor binding(GO:0005172) |
| 0.1 | 0.4 | GO:0004691 | cAMP-dependent protein kinase activity(GO:0004691) |
| 0.1 | 7.6 | GO:0001191 | transcriptional repressor activity, RNA polymerase II transcription factor binding(GO:0001191) |
| 0.1 | 0.3 | GO:0017108 | 5'-flap endonuclease activity(GO:0017108) |
| 0.1 | 0.8 | GO:0010314 | phosphatidylinositol-5-phosphate binding(GO:0010314) |
| 0.1 | 0.2 | GO:0004468 | lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468) |
| 0.1 | 0.2 | GO:0004667 | prostaglandin-D synthase activity(GO:0004667) prostaglandin-E synthase activity(GO:0050220) |
| 0.1 | 0.5 | GO:0035615 | clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748) |
| 0.1 | 4.7 | GO:0005496 | steroid binding(GO:0005496) |
| 0.0 | 1.1 | GO:0030676 | Rac guanyl-nucleotide exchange factor activity(GO:0030676) |
| 0.0 | 0.3 | GO:0035174 | histone serine kinase activity(GO:0035174) |
| 0.0 | 1.0 | GO:0005351 | sugar:proton symporter activity(GO:0005351) |
| 0.0 | 0.2 | GO:0004104 | cholinesterase activity(GO:0004104) choline binding(GO:0033265) |
| 0.0 | 1.1 | GO:0034930 | N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517) heparan sulfate 2-O-sulfotransferase activity(GO:0004394) HNK-1 sulfotransferase activity(GO:0016232) heparan sulfate 6-O-sulfotransferase activity(GO:0017095) trans-9R,10R-dihydrodiolphenanthrene sulfotransferase activity(GO:0018721) 1-phenanthrol sulfotransferase activity(GO:0018722) 3-phenanthrol sulfotransferase activity(GO:0018723) 4-phenanthrol sulfotransferase activity(GO:0018724) trans-3,4-dihydrodiolphenanthrene sulfotransferase activity(GO:0018725) 9-phenanthrol sulfotransferase activity(GO:0018726) 2-phenanthrol sulfotransferase activity(GO:0018727) phenanthrol sulfotransferase activity(GO:0019111) 1-hydroxypyrene sulfotransferase activity(GO:0034930) proteoglycan sulfotransferase activity(GO:0050698) cholesterol sulfotransferase activity(GO:0051922) hydroxyjasmonate sulfotransferase activity(GO:0080131) |
| 0.0 | 0.2 | GO:0004839 | ubiquitin activating enzyme activity(GO:0004839) |
| 0.0 | 0.2 | GO:0042610 | CD8 receptor binding(GO:0042610) |
| 0.0 | 0.5 | GO:0016208 | AMP binding(GO:0016208) |
| 0.0 | 0.5 | GO:0070006 | metalloaminopeptidase activity(GO:0070006) |
| 0.0 | 0.1 | GO:0030620 | U2 snRNA binding(GO:0030620) |
| 0.0 | 0.9 | GO:0030215 | semaphorin receptor binding(GO:0030215) |
| 0.0 | 0.6 | GO:0035259 | glucocorticoid receptor binding(GO:0035259) |
| 0.0 | 0.5 | GO:0070530 | K63-linked polyubiquitin binding(GO:0070530) |
| 0.0 | 0.1 | GO:0045504 | dynein heavy chain binding(GO:0045504) |
| 0.0 | 0.8 | GO:0017080 | sodium channel regulator activity(GO:0017080) |
| 0.0 | 0.2 | GO:0016500 | protein-hormone receptor activity(GO:0016500) |
| 0.0 | 0.5 | GO:0050136 | NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136) |
| 0.0 | 0.2 | GO:0004745 | retinol dehydrogenase activity(GO:0004745) |
| 0.0 | 1.1 | GO:0005200 | structural constituent of cytoskeleton(GO:0005200) |
| 0.0 | 0.2 | GO:0005225 | volume-sensitive anion channel activity(GO:0005225) |
| 0.0 | 1.6 | GO:0005125 | cytokine activity(GO:0005125) |
| 0.0 | 0.2 | GO:1990841 | promoter-specific chromatin binding(GO:1990841) |
| 0.0 | 0.5 | GO:0005086 | ARF guanyl-nucleotide exchange factor activity(GO:0005086) |
| 0.0 | 0.0 | GO:0047192 | 1-alkylglycerophosphocholine O-acetyltransferase activity(GO:0047192) |
| 0.0 | 1.5 | GO:0001085 | RNA polymerase II transcription factor binding(GO:0001085) |
| 0.0 | 0.4 | GO:0043015 | gamma-tubulin binding(GO:0043015) |
| 0.0 | 0.1 | GO:0046933 | proton-transporting ATP synthase activity, rotational mechanism(GO:0046933) |
| 0.0 | 0.1 | GO:0070061 | fructose binding(GO:0070061) |
