Motif ID: Pou2f2_Pou3f1

Z-value: 1.399

Transcription factors associated with Pou2f2_Pou3f1:

Gene SymbolEntrez IDGene Name
Pou2f2 ENSMUSG00000008496.12 Pou2f2
Pou3f1 ENSMUSG00000090125.2 Pou3f1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Pou2f2mm10_v2_chr7_-_25132473_25132512-0.332.5e-01Click!
Pou3f1mm10_v2_chr4_+_124657646_124657656-0.214.6e-01Click!


Activity profile for motif Pou2f2_Pou3f1.

activity profile for motif Pou2f2_Pou3f1


Sorted Z-values histogram for motif Pou2f2_Pou3f1

Sorted Z-values for motif Pou2f2_Pou3f1



Network of associatons between targets according to the STRING database.



First level regulatory network of Pou2f2_Pou3f1

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr7_+_45017953 5.482 ENSMUST00000044111.7
 Rras
Harvey rat sarcoma oncogene, subgroup R
chr7_+_24507099 3.601 ENSMUST00000177228.1
 Zfp428
zinc finger protein 428
chr7_+_24507122 3.007 ENSMUST00000177205.1
 Zfp428
zinc finger protein 428
chr7_+_24507057 2.864 ENSMUST00000071361.6
 Zfp428
zinc finger protein 428
chr7_+_24507006 2.826 ENSMUST00000176880.1
 Zfp428
zinc finger protein 428
chr13_+_23746734 2.720 ENSMUST00000099703.2
 Hist1h2bb
histone cluster 1, H2bb
chr4_+_97777606 1.962 ENSMUST00000075448.6
ENSMUST00000092532.6
 Nfia

nuclear factor I/A

chr2_-_36105271 1.796 ENSMUST00000112960.1
ENSMUST00000112967.5
ENSMUST00000112963.1
 Lhx6


LIM homeobox protein 6


chr1_-_165934900 1.764 ENSMUST00000069609.5
ENSMUST00000111427.2
ENSMUST00000111426.4
 Pou2f1


POU domain, class 2, transcription factor 1


chr7_-_102100227 1.625 ENSMUST00000106937.1
 Art5
ADP-ribosyltransferase 5
chr3_+_83766300 1.611 ENSMUST00000029625.7
 Sfrp2
secreted frizzled-related protein 2
chr2_+_105675478 1.564 ENSMUST00000167211.2
ENSMUST00000111083.3
 Pax6

paired box gene 6

chrX_-_167209149 1.519 ENSMUST00000112176.1
 Tmsb4x
thymosin, beta 4, X chromosome
chr14_+_13453937 1.515 ENSMUST00000153954.1
 Synpr
synaptoporin
chr13_-_83729544 1.448 ENSMUST00000181705.1
 Gm26803
predicted gene, 26803
chr11_-_63922257 1.395 ENSMUST00000094103.3
 Hs3st3b1
heparan sulfate (glucosamine) 3-O-sulfotransferase 3B1
chr17_-_58991343 1.392 ENSMUST00000025064.7
 2610034M16Rik
RIKEN cDNA 2610034M16 gene
chr14_+_13454010 1.391 ENSMUST00000112656.2
 Synpr
synaptoporin
chr2_+_105675429 1.354 ENSMUST00000111085.1
 Pax6
paired box gene 6
chr13_-_56252163 1.315 ENSMUST00000058475.4
 Neurog1
neurogenin 1

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 94 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 5.5 GO:0060325 face morphogenesis(GO:0060325)
0.6 2.9 GO:0021905 pancreatic A cell development(GO:0003322) forebrain-midbrain boundary formation(GO:0021905) somatic motor neuron fate commitment(GO:0021917) regulation of transcription from RNA polymerase II promoter involved in somatic motor neuron fate commitment(GO:0021918)
0.1 2.6 GO:0006471 protein ADP-ribosylation(GO:0006471)
0.4 2.2 GO:1904936 cerebral cortex GABAergic interneuron migration(GO:0021853) interneuron migration(GO:1904936)
0.2 2.2 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.3 2.1 GO:2000124 regulation of endocannabinoid signaling pathway(GO:2000124)
0.1 2.1 GO:0033234 negative regulation of protein sumoylation(GO:0033234)
0.0 2.0 GO:0006284 base-excision repair(GO:0006284)
0.3 1.8 GO:0071699 olfactory placode formation(GO:0030910) olfactory placode development(GO:0071698) olfactory placode morphogenesis(GO:0071699)
0.5 1.6 GO:1904956 dermatome development(GO:0061054) regulation of dermatome development(GO:0061183) regulation of midbrain dopaminergic neuron differentiation(GO:1904956) regulation of planar cell polarity pathway involved in axis elongation(GO:2000040) negative regulation of planar cell polarity pathway involved in axis elongation(GO:2000041)
0.2 1.5 GO:0051152 positive regulation of smooth muscle cell differentiation(GO:0051152)
0.1 1.5 GO:0043171 peptide catabolic process(GO:0043171)
0.2 1.4 GO:0006477 protein sulfation(GO:0006477)
0.2 1.4 GO:0018401 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401)
0.1 1.4 GO:0010748 negative regulation of plasma membrane long-chain fatty acid transport(GO:0010748) positive regulation of fatty acid beta-oxidation(GO:0032000)
0.2 1.3 GO:0031536 positive regulation of exit from mitosis(GO:0031536)
0.1 1.3 GO:0021521 ventral spinal cord interneuron specification(GO:0021521) cell fate specification involved in pattern specification(GO:0060573)
0.4 1.2 GO:0002765 immune response-inhibiting signal transduction(GO:0002765) positive regulation of dendritic cell apoptotic process(GO:2000670)
0.2 1.2 GO:2000774 positive regulation of cellular senescence(GO:2000774)
0.0 1.2 GO:0060074 synapse maturation(GO:0060074)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 32 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 5.4 GO:0005925 focal adhesion(GO:0005925)
0.3 2.9 GO:0030285 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.5 2.1 GO:0002111 BRCA2-BRAF35 complex(GO:0002111)
0.3 2.0 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
0.0 1.6 GO:0043204 perikaryon(GO:0043204)
0.1 1.4 GO:0032593 insulin-responsive compartment(GO:0032593)
0.0 1.3 GO:0000786 nucleosome(GO:0000786)
0.4 1.2 GO:0034666 integrin alpha2-beta1 complex(GO:0034666)
0.0 1.2 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.4 1.1 GO:0043540 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex(GO:0043540)
0.1 1.1 GO:0032279 asymmetric synapse(GO:0032279)
0.0 0.9 GO:0001669 acrosomal vesicle(GO:0001669)
0.2 0.8 GO:0061702 inflammasome complex(GO:0061702)
0.1 0.8 GO:0043196 varicosity(GO:0043196)
0.0 0.8 GO:0035102 PRC1 complex(GO:0035102)
0.0 0.8 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 0.8 GO:0005912 adherens junction(GO:0005912)
0.1 0.7 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.0 0.7 GO:0016592 mediator complex(GO:0016592)
0.0 0.7 GO:0032993 protein-DNA complex(GO:0032993)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 54 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 5.5 GO:0019003 GDP binding(GO:0019003)
0.0 3.6 GO:0001047 core promoter binding(GO:0001047)
0.3 2.9 GO:0003680 AT DNA binding(GO:0003680)
0.8 2.4 GO:0003953 NAD+ nucleosidase activity(GO:0003953)
0.2 2.1 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.2 2.0 GO:0051575 5'-deoxyribose-5-phosphate lyase activity(GO:0051575)
0.0 1.7 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.2 1.6 GO:0061133 endopeptidase activator activity(GO:0061133)
0.1 1.5 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.2 1.4 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.2 1.4 GO:0031545 peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.0 1.4 GO:0003785 actin monomer binding(GO:0003785)
0.0 1.4 GO:0070888 E-box binding(GO:0070888)
0.4 1.2 GO:0005128 erythropoietin receptor binding(GO:0005128)
0.0 1.2 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.2 1.1 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.2 1.1 GO:0070095 fructose-6-phosphate binding(GO:0070095)
0.0 1.1 GO:0071837 HMG box domain binding(GO:0071837)
0.0 1.1 GO:0005112 Notch binding(GO:0005112)
0.2 0.9 GO:0001758 retinal dehydrogenase activity(GO:0001758) 3-chloroallyl aldehyde dehydrogenase activity(GO:0004028)