Motif ID: Pou3f2

Z-value: 0.763


Transcription factors associated with Pou3f2:

Gene SymbolEntrez IDGene Name
Pou3f2 ENSMUSG00000095139.1 Pou3f2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Pou3f2mm10_v2_chr4_-_22488296_224883660.814.2e-04Click!


Activity profile for motif Pou3f2.

activity profile for motif Pou3f2


Sorted Z-values histogram for motif Pou3f2

Sorted Z-values for motif Pou3f2



Network of associatons between targets according to the STRING database.



First level regulatory network of Pou3f2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr7_+_51621830 2.224 ENSMUST00000032710.5
 Slc17a6
solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 6
chr14_-_88471396 1.674 ENSMUST00000061628.5
 Pcdh20
protocadherin 20
chr14_-_103843685 1.516 ENSMUST00000172237.1
 Ednrb
endothelin receptor type B
chr14_-_103844173 1.474 ENSMUST00000022718.3
 Ednrb
endothelin receptor type B
chr9_+_44981779 1.190 ENSMUST00000034602.7
 Cd3d
CD3 antigen, delta polypeptide
chr14_+_84443553 1.124 ENSMUST00000071370.5
 Pcdh17
protocadherin 17
chr1_+_195017399 1.117 ENSMUST00000181273.1
 A330023F24Rik
RIKEN cDNA A330023F24 gene
chr10_+_57794335 1.011 ENSMUST00000151623.1
ENSMUST00000020022.7
 Smpdl3a

sphingomyelin phosphodiesterase, acid-like 3A

chr3_+_141465564 1.006 ENSMUST00000106236.2
ENSMUST00000075282.3
 Unc5c

unc-5 homolog C (C. elegans)

chr17_-_46032366 0.986 ENSMUST00000071648.5
ENSMUST00000142351.2
ENSMUST00000167860.1
 Vegfa


vascular endothelial growth factor A


chr18_+_5593566 0.977 ENSMUST00000160910.1
 Zeb1
zinc finger E-box binding homeobox 1
chr17_-_46031813 0.947 ENSMUST00000024747.7
 Vegfa
vascular endothelial growth factor A
chr2_-_60125651 0.939 ENSMUST00000112550.1
 Baz2b
bromodomain adjacent to zinc finger domain, 2B
chr3_+_141465592 0.792 ENSMUST00000130636.1
 Unc5c
unc-5 homolog C (C. elegans)
chr1_-_150392719 0.720 ENSMUST00000006167.6
ENSMUST00000094477.2
ENSMUST00000097547.3
 BC003331


cDNA sequence BC003331


chr5_-_148392810 0.688 ENSMUST00000138257.1
 Slc7a1
solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
chr6_+_29694204 0.667 ENSMUST00000046750.7
ENSMUST00000115250.3
 Tspan33

tetraspanin 33

chr3_+_88965812 0.658 ENSMUST00000090933.4
 Ash1l
ash1 (absent, small, or homeotic)-like (Drosophila)
chr17_+_39846958 0.636 ENSMUST00000182010.1
 Gm26924
predicted gene, 26924
chr3_+_88207308 0.607 ENSMUST00000180582.1
 Gm3764
predicted gene 3764
chr8_-_57962564 0.605 ENSMUST00000098757.3
 Galntl6
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase-like 6
chr11_-_23519181 0.591 ENSMUST00000020527.5
 1700093K21Rik
RIKEN cDNA 1700093K21 gene
chr13_-_74376566 0.575 ENSMUST00000091481.2
 Zfp72
zinc finger protein 72
chr18_+_37400845 0.542 ENSMUST00000057228.1
 Pcdhb9
protocadherin beta 9
chr16_+_36875119 0.530 ENSMUST00000135406.1
ENSMUST00000114812.1
ENSMUST00000134616.1
ENSMUST00000023534.6
 Golgb1


Golgb1
golgi autoantigen, golgin subfamily b, macrogolgin 1


golgi autoantigen, golgin subfamily b, macrogolgin 1
chr3_+_88206786 0.516 ENSMUST00000181134.1
ENSMUST00000181550.1
 Gm3764

predicted gene 3764

chr14_-_16575456 0.512 ENSMUST00000063750.6
 Rarb
retinoic acid receptor, beta
chr14_+_80000292 0.490 ENSMUST00000088735.3
 Olfm4
olfactomedin 4
chr14_+_99046406 0.448 ENSMUST00000022656.6
 Bora
bora, aurora kinase A activator
chr16_-_17561240 0.445 ENSMUST00000065125.5
ENSMUST00000100123.3
ENSMUST00000023442.6
 4930451C15Rik


RIKEN cDNA 4930451C15 gene


chr11_+_23256566 0.442 ENSMUST00000136235.1
 Xpo1
exportin 1, CRM1 homolog (yeast)
chr4_-_109665249 0.431 ENSMUST00000063531.4
 Cdkn2c
cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)
chr6_+_90465287 0.394 ENSMUST00000113530.1
 Klf15
Kruppel-like factor 15
chr13_-_110280103 0.385 ENSMUST00000167824.1
 Rab3c
RAB3C, member RAS oncogene family
chr17_+_43389436 0.373 ENSMUST00000113599.1
 Gpr116
G protein-coupled receptor 116
chr18_+_37435602 0.373 ENSMUST00000055495.5
 Pcdhb12
protocadherin beta 12
chr3_-_36571952 0.370 ENSMUST00000029270.3
 Ccna2
cyclin A2
chr14_-_47418407 0.355 ENSMUST00000043296.3
 Dlgap5
discs, large (Drosophila) homolog-associated protein 5
chr10_-_53630439 0.349 ENSMUST00000075540.5
 Mcm9
minichromosome maintenance complex component 9
chr11_+_23256001 0.346 ENSMUST00000020538.6
ENSMUST00000109551.1
ENSMUST00000102870.1
ENSMUST00000102869.1
 Xpo1



exportin 1, CRM1 homolog (yeast)



chr4_-_110286581 0.332 ENSMUST00000138972.1
 Elavl4
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D)
chr6_+_41605482 0.330 ENSMUST00000114732.2
 Ephb6
Eph receptor B6
chr12_+_51377560 0.322 ENSMUST00000021335.5
 Scfd1
Sec1 family domain containing 1
chr5_+_14025305 0.312 ENSMUST00000073957.6
 Sema3e
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E
chr8_-_41054771 0.312 ENSMUST00000093534.4
 Mtus1
mitochondrial tumor suppressor 1
chr3_+_66985700 0.307 ENSMUST00000046542.6
ENSMUST00000162693.1
 Rsrc1

arginine/serine-rich coiled-coil 1

chrX_-_145505136 0.295 ENSMUST00000112835.1
 Amot
angiomotin
chr10_-_69352886 0.292 ENSMUST00000119827.1
ENSMUST00000020099.5
 Cdk1

cyclin-dependent kinase 1

chr15_+_36179530 0.291 ENSMUST00000171205.1
 Spag1
sperm associated antigen 1
chr19_+_60144682 0.285 ENSMUST00000065383.4
 E330013P04Rik
RIKEN cDNA E330013P04 gene
chr7_+_16781341 0.269 ENSMUST00000108496.2
 Slc1a5
solute carrier family 1 (neutral amino acid transporter), member 5
chr5_-_111761697 0.265 ENSMUST00000129146.1
ENSMUST00000137398.1
ENSMUST00000129065.1
 E130006D01Rik


RIKEN cDNA E130006D01 gene


chr3_+_66985647 0.257 ENSMUST00000162362.1
ENSMUST00000065074.7
 Rsrc1

arginine/serine-rich coiled-coil 1

chr11_-_50931612 0.248 ENSMUST00000109124.3
 Zfp354b
zinc finger protein 354B
chr6_+_34384218 0.246 ENSMUST00000038383.7
ENSMUST00000115051.1
 Akr1b10

aldo-keto reductase family 1, member B10 (aldose reductase)

chr12_+_69241832 0.237 ENSMUST00000063445.6
 Klhdc1
kelch domain containing 1
chrX_-_162159717 0.221 ENSMUST00000087085.3
 Nhs
Nance-Horan syndrome (human)
chr3_+_66985680 0.221 ENSMUST00000065047.6
 Rsrc1
arginine/serine-rich coiled-coil 1
chr3_+_66985947 0.219 ENSMUST00000161726.1
ENSMUST00000160504.1
 Rsrc1

arginine/serine-rich coiled-coil 1

chr1_-_72212249 0.219 ENSMUST00000048860.7
 Mreg
melanoregulin
chr4_-_149126688 0.217 ENSMUST00000030815.2
 Cort
cortistatin
chr3_+_27984145 0.216 ENSMUST00000067757.4
 Pld1
phospholipase D1
chr9_+_88839164 0.207 ENSMUST00000163255.2
 Trim43c
tripartite motif-containing 43C
chr18_-_43477764 0.204 ENSMUST00000057110.9
 Eif3j2
eukaryotic translation initiation factor 3, subunit J2
chr4_-_108780503 0.203 ENSMUST00000106658.1
 Zfyve9
zinc finger, FYVE domain containing 9
chr5_+_86804508 0.199 ENSMUST00000038384.7
 Ythdc1
YTH domain containing 1
chr4_-_108780782 0.192 ENSMUST00000106657.1
 Zfyve9
zinc finger, FYVE domain containing 9
chrX_-_59166080 0.156 ENSMUST00000119306.1
 Fgf13
fibroblast growth factor 13
chr12_-_91384403 0.155 ENSMUST00000141429.1
 Cep128
centrosomal protein 128
chr4_+_11758147 0.153 ENSMUST00000029871.5
ENSMUST00000108303.1
 Cdh17

cadherin 17

chr12_-_31351368 0.129 ENSMUST00000110857.3
 Dld
dihydrolipoamide dehydrogenase
chr5_+_122284365 0.124 ENSMUST00000053426.8
 Pptc7
PTC7 protein phosphatase homolog (S. cerevisiae)
chr8_-_41041828 0.123 ENSMUST00000051379.7
 Mtus1
mitochondrial tumor suppressor 1
chrX_-_145505175 0.122 ENSMUST00000143610.1
 Amot
angiomotin
chr19_-_20390944 0.119 ENSMUST00000025561.7
 Anxa1
annexin A1
chr6_-_99632376 0.119 ENSMUST00000176255.1
 Gm20696
predicted gene 20696
chr19_+_38930909 0.118 ENSMUST00000025965.5
 Hells
helicase, lymphoid specific
chr2_+_61593077 0.104 ENSMUST00000112495.1
ENSMUST00000112501.2
 Tank

TRAF family member-associated Nf-kappa B activator

chr9_-_89092835 0.103 ENSMUST00000167113.1
 Trim43b
tripartite motif-containing 43B
chr8_-_123236198 0.096 ENSMUST00000166768.1
ENSMUST00000098327.1
 Spata2l

spermatogenesis associated 2-like

chr19_+_44203265 0.091 ENSMUST00000026220.5
 Scd3
stearoyl-coenzyme A desaturase 3
chr2_+_65930117 0.084 ENSMUST00000176109.1
 Csrnp3
cysteine-serine-rich nuclear protein 3
chr16_+_44867097 0.082 ENSMUST00000102805.3
 Cd200r2
Cd200 receptor 2
chr8_+_85432686 0.080 ENSMUST00000180883.1
 1700051O22Rik
RIKEN cDNA 1700051O22 Gene
chr12_+_52699297 0.079 ENSMUST00000095737.3
 Akap6
A kinase (PRKA) anchor protein 6
chr13_+_96388294 0.077 ENSMUST00000099295.4
 Poc5
POC5 centriolar protein homolog (Chlamydomonas)
chr7_+_44836286 0.075 ENSMUST00000033015.7
 Il4i1
interleukin 4 induced 1
chr2_+_65620829 0.072 ENSMUST00000028377.7
 Scn2a1
sodium channel, voltage-gated, type II, alpha 1
chr14_+_79515618 0.068 ENSMUST00000110835.1
 Elf1
E74-like factor 1
chr9_+_88581036 0.063 ENSMUST00000164661.2
 Trim43a
tripartite motif-containing 43A
chr16_-_36874806 0.049 ENSMUST00000075946.5
 Eaf2
ELL associated factor 2
chr2_+_140152043 0.042 ENSMUST00000104994.2
 Gm17374
predicted gene, 17374
chr3_-_157925056 0.036 ENSMUST00000118539.1
 Cth
cystathionase (cystathionine gamma-lyase)
chr5_+_107497762 0.034 ENSMUST00000152474.1
ENSMUST00000060553.7
 A830010M20Rik

RIKEN cDNA A830010M20 gene

chr3_-_51560816 0.016 ENSMUST00000037141.7
 Setd7
SET domain containing (lysine methyltransferase) 7
chr3_+_103809520 0.015 ENSMUST00000076599.1
ENSMUST00000106824.1
ENSMUST00000106823.1
ENSMUST00000047285.2
 Ap4b1



adaptor-related protein complex AP-4, beta 1



chr1_+_74661714 0.012 ENSMUST00000042125.8
ENSMUST00000141119.1
 Ttll4

tubulin tyrosine ligase-like family, member 4

chr2_+_80315461 0.011 ENSMUST00000028392.7
 Dnajc10
DnaJ (Hsp40) homolog, subfamily C, member 10
chr2_-_136387929 0.009 ENSMUST00000035264.2
ENSMUST00000077200.3
 Pak7

p21 protein (Cdc42/Rac)-activated kinase 7

chr16_-_36784784 0.008 ENSMUST00000165531.1
 Slc15a2
solute carrier family 15 (H+/peptide transporter), member 2
chr5_+_107497718 0.006 ENSMUST00000112671.2
 A830010M20Rik
RIKEN cDNA A830010M20 gene
chr13_+_49582745 0.002 ENSMUST00000065494.7
 Omd
osteomodulin

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 3.0 GO:0014826 vein smooth muscle contraction(GO:0014826)
0.6 1.9 GO:1902336 neuropilin signaling pathway(GO:0038189) VEGF-activated neuropilin signaling pathway(GO:0038190) positive regulation of retinal ganglion cell axon guidance(GO:1902336)
0.2 1.8 GO:0033564 anterior/posterior axon guidance(GO:0033564)
0.1 1.0 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.1 1.2 GO:0045059 positive thymic T cell selection(GO:0045059)
0.1 0.8 GO:0000056 ribosomal small subunit export from nucleus(GO:0000056)
0.1 0.7 GO:1903352 ornithine transport(GO:0015822) L-ornithine transmembrane transport(GO:1903352)
0.1 1.1 GO:2000807 regulation of synaptic vesicle clustering(GO:2000807)
0.1 1.0 GO:0048752 semicircular canal morphogenesis(GO:0048752)
0.1 0.4 GO:0003365 establishment of cell polarity involved in ameboidal cell migration(GO:0003365)
0.1 2.2 GO:0001504 neurotransmitter uptake(GO:0001504)
0.1 0.5 GO:0003406 retinal pigment epithelium development(GO:0003406)
0.1 0.3 GO:2000525 regulation of T cell costimulation(GO:2000523) positive regulation of T cell costimulation(GO:2000525)
0.1 0.7 GO:0002674 negative regulation of acute inflammatory response(GO:0002674)
0.1 0.6 GO:0044791 modulation by host of viral release from host cell(GO:0044789) positive regulation by host of viral release from host cell(GO:0044791)
0.1 0.2 GO:0002314 germinal center B cell differentiation(GO:0002314)
0.0 0.1 GO:0009106 lipoate metabolic process(GO:0009106)
0.0 0.1 GO:0036292 positive regulation of prostaglandin biosynthetic process(GO:0031394) DNA rewinding(GO:0036292) positive regulation of unsaturated fatty acid biosynthetic process(GO:2001280)
0.0 0.1 GO:0032512 regulation of protein phosphatase type 2B activity(GO:0032512)
0.0 0.3 GO:0090166 Golgi disassembly(GO:0090166)
0.0 0.2 GO:0032534 regulation of microvillus assembly(GO:0032534)
0.0 1.0 GO:0046677 response to antibiotic(GO:0046677)
0.0 0.3 GO:1902902 negative regulation of autophagosome assembly(GO:1902902)
0.0 0.4 GO:0072010 renal filtration cell differentiation(GO:0061318) glomerular epithelium development(GO:0072010) glomerular visceral epithelial cell differentiation(GO:0072112) glomerular epithelial cell differentiation(GO:0072311)
0.0 0.4 GO:0010758 regulation of macrophage chemotaxis(GO:0010758)
0.0 0.1 GO:1903966 monounsaturated fatty acid metabolic process(GO:1903964) monounsaturated fatty acid biosynthetic process(GO:1903966)
0.0 0.4 GO:0060236 regulation of mitotic spindle organization(GO:0060236)
0.0 0.3 GO:0015825 L-serine transport(GO:0015825)
0.0 0.2 GO:0045200 establishment or maintenance of neuroblast polarity(GO:0045196) establishment of neuroblast polarity(GO:0045200)
0.0 1.7 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 0.4 GO:0007183 SMAD protein complex assembly(GO:0007183)
0.0 0.2 GO:0045187 regulation of circadian sleep/wake cycle(GO:0042749) regulation of circadian sleep/wake cycle, sleep(GO:0045187)
0.0 0.0 GO:1905065 positive regulation of vascular smooth muscle cell differentiation(GO:1905065)
0.0 0.1 GO:0008627 intrinsic apoptotic signaling pathway in response to osmotic stress(GO:0008627)
0.0 0.7 GO:0045747 positive regulation of Notch signaling pathway(GO:0045747)
0.0 0.1 GO:0031508 pericentric heterochromatin assembly(GO:0031508)
0.0 0.2 GO:0042640 anagen(GO:0042640)
0.0 0.0 GO:0060770 negative regulation of epithelial cell proliferation involved in prostate gland development(GO:0060770)
0.0 0.5 GO:1900026 positive regulation of substrate adhesion-dependent cell spreading(GO:1900026)
0.0 0.3 GO:0001953 negative regulation of cell-matrix adhesion(GO:0001953)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.2 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.1 0.7 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.1 0.8 GO:0005642 annulate lamellae(GO:0005642)
0.1 0.4 GO:0001940 male pronucleus(GO:0001940)
0.0 0.4 GO:0072687 meiotic spindle(GO:0072687)
0.0 2.2 GO:0030672 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.0 0.5 GO:0042581 specific granule(GO:0042581)
0.0 0.1 GO:0001533 cornified envelope(GO:0001533)
0.0 0.3 GO:0042788 polysomal ribosome(GO:0042788)
0.0 0.4 GO:0031616 spindle pole centrosome(GO:0031616)
0.0 0.3 GO:0042555 MCM complex(GO:0042555)
0.0 0.3 GO:0017119 Golgi transport complex(GO:0017119)
0.0 1.9 GO:0005604 basement membrane(GO:0005604)
0.0 0.1 GO:0045254 pyruvate dehydrogenase complex(GO:0045254)
0.0 2.8 GO:0031965 nuclear membrane(GO:0031965)
0.0 0.5 GO:0005801 cis-Golgi network(GO:0005801)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 3.0 GO:0004962 endothelin receptor activity(GO:0004962)
0.6 1.9 GO:0043183 vascular endothelial growth factor receptor 1 binding(GO:0043183)
0.3 1.8 GO:0005042 netrin receptor activity(GO:0005042)
0.1 0.4 GO:0043532 angiostatin binding(GO:0043532)
0.1 1.0 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.1 2.2 GO:0005313 L-glutamate transmembrane transporter activity(GO:0005313)
0.1 0.7 GO:0046975 histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.1 0.7 GO:0015189 L-ornithine transmembrane transporter activity(GO:0000064) arginine transmembrane transporter activity(GO:0015181) L-lysine transmembrane transporter activity(GO:0015189)
0.1 0.2 GO:0035673 oligopeptide transmembrane transporter activity(GO:0035673)
0.0 0.2 GO:0052650 retinal binding(GO:0016918) NADP-retinol dehydrogenase activity(GO:0052650)
0.0 0.3 GO:0038191 neuropilin binding(GO:0038191)
0.0 0.4 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.0 0.1 GO:0004859 phospholipase inhibitor activity(GO:0004859) phospholipase A2 inhibitor activity(GO:0019834)
0.0 0.2 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.0 0.7 GO:0005487 nucleocytoplasmic transporter activity(GO:0005487)
0.0 0.1 GO:0001716 L-amino-acid oxidase activity(GO:0001716)
0.0 0.5 GO:0003708 retinoic acid receptor activity(GO:0003708)
0.0 0.1 GO:0032896 palmitoyl-CoA 9-desaturase activity(GO:0032896)
0.0 1.0 GO:0070888 E-box binding(GO:0070888)
0.0 0.1 GO:0034604 pyruvate dehydrogenase activity(GO:0004738) pyruvate dehydrogenase [NAD(P)+] activity(GO:0034603) pyruvate dehydrogenase (NAD+) activity(GO:0034604)
0.0 0.4 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.0 0.3 GO:0022889 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.0 0.2 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
0.0 0.4 GO:0031489 myosin V binding(GO:0031489)
0.0 0.3 GO:0035173 histone kinase activity(GO:0035173)
0.0 0.1 GO:0043495 protein anchor(GO:0043495)
0.0 0.2 GO:0005184 neuropeptide hormone activity(GO:0005184)