Motif ID: Pou4f1_Pou6f1

Z-value: 1.193

Transcription factors associated with Pou4f1_Pou6f1:

Gene SymbolEntrez IDGene Name
Pou4f1 ENSMUSG00000048349.8 Pou4f1
Pou6f1 ENSMUSG00000009739.10 Pou6f1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Pou6f1mm10_v2_chr15_-_100599983_100600039-0.204.9e-01Click!
Pou4f1mm10_v2_chr14_-_104467984_1044680410.039.2e-01Click!


Activity profile for motif Pou4f1_Pou6f1.

activity profile for motif Pou4f1_Pou6f1


Sorted Z-values histogram for motif Pou4f1_Pou6f1

Sorted Z-values for motif Pou4f1_Pou6f1



Network of associatons between targets according to the STRING database.



First level regulatory network of Pou4f1_Pou6f1

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr10_-_64090241 5.710 ENSMUST00000133588.1
 Lrrtm3
leucine rich repeat transmembrane neuronal 3
chr13_-_56252163 4.644 ENSMUST00000058475.4
 Neurog1
neurogenin 1
chr10_-_64090265 1.974 ENSMUST00000105439.1
 Lrrtm3
leucine rich repeat transmembrane neuronal 3
chr1_-_172057573 1.972 ENSMUST00000059794.3
 Nhlh1
nescient helix loop helix 1
chr17_-_50094277 1.754 ENSMUST00000113195.1
 Rftn1
raftlin lipid raft linker 1
chr1_+_12692430 1.488 ENSMUST00000180062.1
ENSMUST00000177608.1
 Sulf1

sulfatase 1

chr11_+_98348404 1.475 ENSMUST00000078694.6
 Ppp1r1b
protein phosphatase 1, regulatory (inhibitor) subunit 1B
chr2_+_175968942 1.291 ENSMUST00000109008.3
 Gm2026
predicted gene 2026
chr2_+_176711933 1.220 ENSMUST00000108983.2
 Gm14305
predicted gene 14305
chr12_-_108003594 1.180 ENSMUST00000066060.4
 Bcl11b
B cell leukemia/lymphoma 11B
chr2_-_175432182 1.178 ENSMUST00000109046.3
 Gm4724
predicted gene 4724
chr2_-_176483160 1.165 ENSMUST00000122097.2
 Gm14434
predicted gene 14434
chr6_+_80018877 1.163 ENSMUST00000147663.1
ENSMUST00000128718.1
ENSMUST00000126005.1
ENSMUST00000133918.1
 Lrrtm4



leucine rich repeat transmembrane neuronal 4



chr6_+_80019008 1.156 ENSMUST00000126399.1
ENSMUST00000136421.1
 Lrrtm4

leucine rich repeat transmembrane neuronal 4

chr9_-_58201705 1.124 ENSMUST00000163200.1
ENSMUST00000165276.1
 Islr2

immunoglobulin superfamily containing leucine-rich repeat 2

chr9_-_58202281 1.107 ENSMUST00000163897.1
 Islr2
immunoglobulin superfamily containing leucine-rich repeat 2
chr10_-_45470201 1.101 ENSMUST00000079390.6
 Lin28b
lin-28 homolog B (C. elegans)
chr2_+_176230177 1.089 ENSMUST00000135430.1
 2210418O10Rik
RIKEN cDNA 2210418O10 gene
chr1_-_158814469 1.088 ENSMUST00000161589.2
 Pappa2
pappalysin 2
chr19_-_23273893 1.020 ENSMUST00000087556.5
 Smc5
structural maintenance of chromosomes 5

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 75 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.5 7.7 GO:1902993 positive regulation of beta-amyloid formation(GO:1902004) positive regulation of amyloid precursor protein catabolic process(GO:1902993)
0.7 4.6 GO:0031536 positive regulation of exit from mitosis(GO:0031536)
0.2 3.0 GO:0097090 presynaptic membrane organization(GO:0097090)
0.0 2.2 GO:0045773 positive regulation of axon extension(GO:0045773)
0.4 1.8 GO:0002457 T cell antigen processing and presentation(GO:0002457)
0.2 1.6 GO:0002681 somatic diversification of T cell receptor genes(GO:0002568) somatic recombination of T cell receptor gene segments(GO:0002681) T cell receptor V(D)J recombination(GO:0033153)
0.5 1.5 GO:0007621 negative regulation of female receptivity(GO:0007621)
0.4 1.5 GO:0014846 esophagus smooth muscle contraction(GO:0014846)
0.1 1.3 GO:0046069 cGMP catabolic process(GO:0046069)
0.1 1.2 GO:0010587 miRNA catabolic process(GO:0010587)
0.1 1.2 GO:0007097 nuclear migration(GO:0007097)
0.3 1.0 GO:0071139 positive regulation of maintenance of sister chromatid cohesion(GO:0034093) positive regulation of maintenance of mitotic sister chromatid cohesion(GO:0034184) resolution of recombination intermediates(GO:0071139)
0.1 1.0 GO:0001780 neutrophil homeostasis(GO:0001780) regulation of high voltage-gated calcium channel activity(GO:1901841)
0.5 0.9 GO:0034372 very-low-density lipoprotein particle remodeling(GO:0034372)
0.1 0.9 GO:0021684 cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.0 0.9 GO:0042541 hemoglobin biosynthetic process(GO:0042541)
0.1 0.8 GO:0097460 ferrous iron import into cell(GO:0097460)
0.1 0.8 GO:0060501 positive regulation of epithelial cell proliferation involved in lung morphogenesis(GO:0060501)
0.0 0.8 GO:0043488 regulation of mRNA stability(GO:0043488)
0.0 0.7 GO:0045494 photoreceptor cell maintenance(GO:0045494)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 22 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 8.4 GO:0045211 postsynaptic membrane(GO:0045211)
0.0 4.6 GO:0043204 perikaryon(GO:0043204)
0.1 2.3 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.1 1.9 GO:0000930 gamma-tubulin complex(GO:0000930)
0.3 1.6 GO:0008623 CHRAC(GO:0008623)
0.3 1.0 GO:0035061 interchromatin granule(GO:0035061)
0.1 0.9 GO:0042627 chylomicron(GO:0042627)
0.1 0.9 GO:0031232 extrinsic component of external side of plasma membrane(GO:0031232)
0.1 0.8 GO:0042788 polysomal ribosome(GO:0042788)
0.1 0.5 GO:0032807 DNA ligase IV complex(GO:0032807)
0.0 0.4 GO:0005641 nuclear envelope lumen(GO:0005641)
0.0 0.4 GO:0097470 ribbon synapse(GO:0097470)
0.1 0.3 GO:0030870 Mre11 complex(GO:0030870)
0.0 0.3 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.1 0.2 GO:0030981 cortical microtubule cytoskeleton(GO:0030981)
0.0 0.2 GO:0097165 nuclear stress granule(GO:0097165)
0.0 0.2 GO:0030485 smooth muscle contractile fiber(GO:0030485)
0.0 0.2 GO:0071556 integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458) integral component of lumenal side of endoplasmic reticulum membrane(GO:0071556) lumenal side of endoplasmic reticulum membrane(GO:0098553)
0.0 0.1 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.0 0.1 GO:0070044 synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 50 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 10.9 GO:0004860 protein kinase inhibitor activity(GO:0004860)
0.1 4.3 GO:0070888 E-box binding(GO:0070888)
0.0 1.8 GO:0003725 double-stranded RNA binding(GO:0003725)
0.5 1.5 GO:0031752 D3 dopamine receptor binding(GO:0031750) D5 dopamine receptor binding(GO:0031752)
0.3 1.5 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.2 1.3 GO:0048101 calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.0 1.1 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 1.0 GO:0030552 cAMP binding(GO:0030552)
0.0 1.0 GO:0017091 AU-rich element binding(GO:0017091)
0.1 0.9 GO:0016594 glycine binding(GO:0016594)
0.0 0.9 GO:0034185 apolipoprotein binding(GO:0034185)
0.1 0.8 GO:0015091 ferric iron transmembrane transporter activity(GO:0015091) trivalent inorganic cation transmembrane transporter activity(GO:0072510)
0.1 0.8 GO:0008499 UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity(GO:0008499)
0.0 0.8 GO:0030159 receptor signaling complex scaffold activity(GO:0030159)
0.0 0.7 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 0.7 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.1 0.6 GO:0032184 SUMO polymer binding(GO:0032184)
0.1 0.6 GO:0000014 single-stranded DNA endodeoxyribonuclease activity(GO:0000014)
0.1 0.5 GO:0015165 pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165)
0.0 0.5 GO:0008395 steroid hydroxylase activity(GO:0008395)