Motif ID: Pou5f1

Z-value: 1.591


Transcription factors associated with Pou5f1:

Gene SymbolEntrez IDGene Name
Pou5f1 ENSMUSG00000024406.10 Pou5f1



Activity profile for motif Pou5f1.

activity profile for motif Pou5f1


Sorted Z-values histogram for motif Pou5f1

Sorted Z-values for motif Pou5f1



Network of associatons between targets according to the STRING database.



First level regulatory network of Pou5f1

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr10_-_64090241 7.608 ENSMUST00000133588.1
 Lrrtm3
leucine rich repeat transmembrane neuronal 3
chr14_-_12345847 7.561 ENSMUST00000022262.4
 Fezf2
Fez family zinc finger 2
chr11_+_110399115 7.052 ENSMUST00000020949.5
ENSMUST00000100260.1
 Map2k6

mitogen-activated protein kinase kinase 6

chr8_+_118283719 6.827 ENSMUST00000117160.1
 Cdh13
cadherin 13
chr4_+_97772734 6.654 ENSMUST00000152023.1
 Nfia
nuclear factor I/A
chr10_-_64090265 6.574 ENSMUST00000105439.1
 Lrrtm3
leucine rich repeat transmembrane neuronal 3
chr13_-_56252163 5.830 ENSMUST00000058475.4
 Neurog1
neurogenin 1
chr3_+_67892189 5.498 ENSMUST00000063263.3
 Iqcj
IQ motif containing J
chr10_+_85386813 5.179 ENSMUST00000105307.1
ENSMUST00000020231.3
 Btbd11

BTB (POZ) domain containing 11

chr6_-_138421379 4.935 ENSMUST00000163065.1
 Lmo3
LIM domain only 3
chr6_+_136518820 4.626 ENSMUST00000032335.6
 Atf7ip
activating transcription factor 7 interacting protein
chr1_-_25228814 4.586 ENSMUST00000126626.1
 Bai3
brain-specific angiogenesis inhibitor 3
chr14_-_102982630 4.277 ENSMUST00000184744.1
 KCTD12
mmu-mir-5130
chr11_-_63922257 3.981 ENSMUST00000094103.3
 Hs3st3b1
heparan sulfate (glucosamine) 3-O-sulfotransferase 3B1
chr6_-_92481343 3.938 ENSMUST00000113445.1
 Prickle2
prickle homolog 2 (Drosophila)
chr14_-_39472825 3.552 ENSMUST00000168810.2
ENSMUST00000173780.1
ENSMUST00000166968.2
 Nrg3


neuregulin 3


chr1_+_153652943 3.550 ENSMUST00000041776.5
 Rgs8
regulator of G-protein signaling 8
chr15_-_66831625 3.534 ENSMUST00000164163.1
 Sla
src-like adaptor
chr8_-_87959560 3.434 ENSMUST00000109655.2
 Zfp423
zinc finger protein 423
chr13_+_5861489 3.342 ENSMUST00000000080.6
 Klf6
Kruppel-like factor 6

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 123 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.9 14.2 GO:1902993 positive regulation of beta-amyloid formation(GO:1902004) positive regulation of amyloid precursor protein catabolic process(GO:1902993)
0.3 8.3 GO:0010971 positive regulation of G2/M transition of mitotic cell cycle(GO:0010971)
1.3 7.6 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.9 7.1 GO:0032308 positive regulation of prostaglandin secretion(GO:0032308)
1.7 6.8 GO:0055095 lipoprotein particle mediated signaling(GO:0055095) low-density lipoprotein particle mediated signaling(GO:0055096)
0.9 6.1 GO:2000124 regulation of endocannabinoid signaling pathway(GO:2000124)
0.8 5.8 GO:0031536 positive regulation of exit from mitosis(GO:0031536)
0.8 5.7 GO:0034047 regulation of protein phosphatase type 2A activity(GO:0034047)
0.4 5.5 GO:0045898 regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898)
0.1 5.2 GO:0060395 SMAD protein signal transduction(GO:0060395)
0.4 5.1 GO:0002227 innate immune response in mucosa(GO:0002227)
0.1 4.9 GO:0045600 positive regulation of fat cell differentiation(GO:0045600)
0.3 4.2 GO:0006337 nucleosome disassembly(GO:0006337) protein-DNA complex disassembly(GO:0032986)
0.5 4.0 GO:0006477 protein sulfation(GO:0006477)
1.3 3.9 GO:0001830 trophectodermal cell fate commitment(GO:0001830)
0.3 3.8 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.0 3.8 GO:0006342 chromatin silencing(GO:0006342)
0.7 3.7 GO:0048631 regulation of skeletal muscle tissue growth(GO:0048631)
0.7 3.7 GO:2000587 regulation of platelet-derived growth factor receptor-beta signaling pathway(GO:2000586) negative regulation of platelet-derived growth factor receptor-beta signaling pathway(GO:2000587)
1.2 3.6 GO:0060596 mammary placode formation(GO:0060596)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 53 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 9.9 GO:0045211 postsynaptic membrane(GO:0045211)
0.5 7.7 GO:0043196 varicosity(GO:0043196)
0.2 7.6 GO:0000788 nuclear nucleosome(GO:0000788)
0.1 7.2 GO:0005901 caveola(GO:0005901)
0.3 5.7 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.1 5.7 GO:0005905 clathrin-coated pit(GO:0005905)
0.1 4.5 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.2 3.9 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.1 3.5 GO:0032809 neuronal cell body membrane(GO:0032809)
0.0 2.9 GO:0043204 perikaryon(GO:0043204)
0.0 2.7 GO:0036064 ciliary basal body(GO:0036064)
0.1 2.5 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.2 2.4 GO:0097449 astrocyte projection(GO:0097449)
0.3 2.2 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
0.0 2.2 GO:0001750 photoreceptor outer segment(GO:0001750)
0.0 2.2 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.4 2.1 GO:0000308 cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308)
0.3 2.1 GO:0042627 chylomicron(GO:0042627)
0.7 2.0 GO:0043512 inhibin A complex(GO:0043512)
0.1 2.0 GO:0034707 chloride channel complex(GO:0034707)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 85 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 13.7 GO:0019210 protein kinase inhibitor activity(GO:0004860) kinase inhibitor activity(GO:0019210)
0.2 7.1 GO:0004708 MAP kinase kinase activity(GO:0004708)
1.4 6.8 GO:0055100 adiponectin binding(GO:0055100)
0.5 6.1 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.4 5.7 GO:0008601 protein phosphatase type 2A regulator activity(GO:0008601)
0.0 5.2 GO:0046982 protein heterodimerization activity(GO:0046982)
0.0 4.1 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.7 4.0 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.1 3.8 GO:0030552 cAMP binding(GO:0030552)
0.1 3.8 GO:0045499 chemorepellent activity(GO:0045499)
0.2 3.7 GO:0034185 apolipoprotein binding(GO:0034185)
0.0 3.5 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.1 2.9 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.2 2.8 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.0 2.8 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.3 2.7 GO:0004806 triglyceride lipase activity(GO:0004806)
0.1 2.5 GO:0070064 proline-rich region binding(GO:0070064)
0.1 2.5 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.8 2.4 GO:0031687 A2A adenosine receptor binding(GO:0031687)
0.0 2.3 GO:0008022 protein C-terminus binding(GO:0008022)