Motif ID: Pou6f2_Pou4f2

Z-value: 1.407

Transcription factors associated with Pou6f2_Pou4f2:

Gene SymbolEntrez IDGene Name
Pou4f2 ENSMUSG00000031688.3 Pou4f2
Pou6f2 ENSMUSG00000009734.11 Pou6f2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Pou4f2mm10_v2_chr8_-_78436640_78436649-0.535.3e-02Click!
Pou6f2mm10_v2_chr13_-_18382041_18382041-0.362.0e-01Click!


Activity profile for motif Pou6f2_Pou4f2.

activity profile for motif Pou6f2_Pou4f2


Sorted Z-values histogram for motif Pou6f2_Pou4f2

Sorted Z-values for motif Pou6f2_Pou4f2



Network of associatons between targets according to the STRING database.



First level regulatory network of Pou6f2_Pou4f2

PNG image of the network

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Top targets:


Showing 1 to 20 of 104 entries
PromoterScoreRefseqGene SymbolGene Name
chr1_+_153665666 13.398 ENSMUST00000111814.1
ENSMUST00000111810.1
 Rgs8

regulator of G-protein signaling 8

chr1_+_153665274 13.355 ENSMUST00000152114.1
ENSMUST00000111812.1
 Rgs8

regulator of G-protein signaling 8

chr13_-_56296551 11.425 ENSMUST00000021970.9
 Cxcl14
chemokine (C-X-C motif) ligand 14
chr1_+_153665587 9.030 ENSMUST00000147700.1
 Rgs8
regulator of G-protein signaling 8
chr1_+_153665627 7.936 ENSMUST00000147482.1
 Rgs8
regulator of G-protein signaling 8
chr12_-_112511136 6.744 ENSMUST00000066791.5
 Tmem179
transmembrane protein 179
chr10_+_99263224 5.947 ENSMUST00000020118.4
 Dusp6
dual specificity phosphatase 6
chr6_+_88724667 5.463 ENSMUST00000163271.1
 Mgll
monoglyceride lipase
chr6_+_88724828 5.273 ENSMUST00000089449.2
 Mgll
monoglyceride lipase
chr6_-_138422898 3.919 ENSMUST00000161450.1
ENSMUST00000163024.1
ENSMUST00000162185.1
 Lmo3


LIM domain only 3


chr6_-_138426735 3.829 ENSMUST00000162932.1
 Lmo3
LIM domain only 3
chr17_+_17402672 3.012 ENSMUST00000115576.2
 Lix1
limb expression 1 homolog (chicken)
chr19_-_19001099 2.663 ENSMUST00000040153.8
ENSMUST00000112828.1
 Rorb

RAR-related orphan receptor beta

chr4_+_102589687 2.434 ENSMUST00000097949.4
ENSMUST00000106901.1
 Pde4b

phosphodiesterase 4B, cAMP specific

chr5_+_139543889 2.219 ENSMUST00000174792.1
ENSMUST00000031523.8
 Uncx

UNC homeobox

chr6_+_77242644 1.854 ENSMUST00000159616.1
 Lrrtm1
leucine rich repeat transmembrane neuronal 1
chr6_+_77242715 1.823 ENSMUST00000161677.1
 Lrrtm1
leucine rich repeat transmembrane neuronal 1
chr1_-_172027269 1.783 ENSMUST00000027837.6
ENSMUST00000111264.1
 Vangl2

vang-like 2 (van gogh, Drosophila)

chr2_+_96318014 1.770 ENSMUST00000135431.1
ENSMUST00000162807.2
 Lrrc4c

leucine rich repeat containing 4C

chr4_-_58499398 1.632 ENSMUST00000107570.1
 Lpar1
lysophosphatidic acid receptor 1

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 41 entries
Log-likelihood per target Total log-likelihoodTermDescription
3.4 43.7 GO:0060159 regulation of dopamine receptor signaling pathway(GO:0060159)
3.8 11.4 GO:2000501 natural killer cell chemotaxis(GO:0035747) regulation of natural killer cell chemotaxis(GO:2000501)
1.5 10.7 GO:2000124 regulation of endocannabinoid signaling pathway(GO:2000124)
0.1 7.7 GO:0045600 positive regulation of fat cell differentiation(GO:0045600)
2.0 5.9 GO:0042663 regulation of endodermal cell fate specification(GO:0042663)
0.2 3.7 GO:0002091 negative regulation of receptor internalization(GO:0002091)
0.2 2.8 GO:1901898 negative regulation of relaxation of muscle(GO:1901078) negative regulation of relaxation of cardiac muscle(GO:1901898)
0.1 2.8 GO:0097352 autophagosome maturation(GO:0097352)
0.4 2.7 GO:0046549 retinal cone cell development(GO:0046549)
0.3 2.2 GO:0035726 common myeloid progenitor cell proliferation(GO:0035726)
0.6 1.8 GO:0060489 establishment of body hair or bristle planar orientation(GO:0048104) establishment of body hair planar orientation(GO:0048105) orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060488) planar dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060489) lateral sprouting involved in lung morphogenesis(GO:0060490)
0.4 1.6 GO:1904565 response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904565) cellular response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904566)
0.1 1.4 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.3 1.3 GO:0060032 notochord regression(GO:0060032)
0.1 1.1 GO:0071493 elastic fiber assembly(GO:0048251) cellular response to UV-B(GO:0071493)
0.1 1.0 GO:0031424 keratinization(GO:0031424) establishment of skin barrier(GO:0061436)
0.0 1.0 GO:0043488 regulation of mRNA stability(GO:0043488)
0.2 0.9 GO:1901204 positive regulation of guanylate cyclase activity(GO:0031284) regulation of adrenergic receptor signaling pathway involved in heart process(GO:1901204)
0.2 0.9 GO:0007256 activation of JNKK activity(GO:0007256)
0.0 0.9 GO:0000154 rRNA modification(GO:0000154)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 26 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.1 43.7 GO:0032809 neuronal cell body membrane(GO:0032809)
0.7 10.7 GO:0043196 varicosity(GO:0043196)
0.0 5.1 GO:0045211 postsynaptic membrane(GO:0045211)
0.1 2.4 GO:0000930 gamma-tubulin complex(GO:0000930)
0.4 1.8 GO:0060187 cell pole(GO:0060187)
0.0 1.6 GO:0043198 dendritic shaft(GO:0043198)
0.1 1.3 GO:0002116 semaphorin receptor complex(GO:0002116)
0.1 1.3 GO:0097542 ciliary tip(GO:0097542)
0.4 1.1 GO:0071953 elastic fiber(GO:0071953)
0.1 1.0 GO:0042788 polysomal ribosome(GO:0042788)
0.0 1.0 GO:0031526 brush border membrane(GO:0031526)
0.1 0.9 GO:0042582 primary lysosome(GO:0005766) azurophil granule(GO:0042582)
0.0 0.9 GO:0042645 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.0 0.8 GO:0016235 aggresome(GO:0016235)
0.0 0.6 GO:0042470 melanosome(GO:0042470) pigment granule(GO:0048770)
0.2 0.5 GO:0030981 cortical microtubule cytoskeleton(GO:0030981)
0.0 0.5 GO:0031527 filopodium membrane(GO:0031527)
0.0 0.4 GO:0005640 nuclear outer membrane(GO:0005640)
0.0 0.4 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.1 0.3 GO:0044302 dentate gyrus mossy fiber(GO:0044302)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 24 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.1 45.4 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.4 11.4 GO:0008009 chemokine activity(GO:0008009)
0.9 10.7 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.2 5.9 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.1 5.6 GO:0004860 protein kinase inhibitor activity(GO:0004860)
0.9 2.7 GO:0008502 melatonin receptor activity(GO:0008502)
0.1 2.4 GO:0030552 cAMP binding(GO:0030552)
0.1 1.3 GO:0017154 semaphorin receptor activity(GO:0017154)
0.0 1.0 GO:0017091 AU-rich element binding(GO:0017091)
0.3 0.9 GO:0004517 nitric-oxide synthase activity(GO:0004517)
0.0 0.9 GO:0043851 rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179) rRNA (uridine-2'-O-)-methyltransferase activity(GO:0008650) rRNA (adenine-N6-)-methyltransferase activity(GO:0008988) rRNA (cytosine-C5-)-methyltransferase activity(GO:0009383) selenocysteine methyltransferase activity(GO:0016205) rRNA (adenine) methyltransferase activity(GO:0016433) rRNA (cytosine) methyltransferase activity(GO:0016434) rRNA (guanine) methyltransferase activity(GO:0016435) 1-phenanthrol methyltransferase activity(GO:0018707) protein-arginine N5-methyltransferase activity(GO:0019702) dimethylarsinite methyltransferase activity(GO:0034541) 4,5-dihydroxybenzo(a)pyrene methyltransferase activity(GO:0034807) 1-hydroxypyrene methyltransferase activity(GO:0034931) 1-hydroxy-6-methoxypyrene methyltransferase activity(GO:0034933) demethylmenaquinone methyltransferase activity(GO:0043770) cobalt-precorrin-6B C5-methyltransferase activity(GO:0043776) cobalt-precorrin-7 C15-methyltransferase activity(GO:0043777) cobalt-precorrin-5B C1-methyltransferase activity(GO:0043780) cobalt-precorrin-3 C17-methyltransferase activity(GO:0043782) dimethylamine methyltransferase activity(GO:0043791) hydroxyneurosporene-O-methyltransferase activity(GO:0043803) tRNA (adenine-57, 58-N(1)-) methyltransferase activity(GO:0043827) methylamine-specific methylcobalamin:coenzyme M methyltransferase activity(GO:0043833) trimethylamine methyltransferase activity(GO:0043834) methanol-specific methylcobalamin:coenzyme M methyltransferase activity(GO:0043851) monomethylamine methyltransferase activity(GO:0043852) P-methyltransferase activity(GO:0051994) Se-methyltransferase activity(GO:0051995) 2-phytyl-1,4-naphthoquinone methyltransferase activity(GO:0052624) tRNA (uracil-2'-O-)-methyltransferase activity(GO:0052665) tRNA (cytosine-2'-O-)-methyltransferase activity(GO:0052666) phosphomethylethanolamine N-methyltransferase activity(GO:0052667) tRNA (cytosine-3-)-methyltransferase activity(GO:0052735) rRNA (cytosine-2'-O-)-methyltransferase activity(GO:0070677) rRNA (cytosine-N4-)-methyltransferase activity(GO:0071424) trihydroxyferuloyl spermidine O-methyltransferase activity(GO:0080012)
0.2 0.8 GO:0035515 oxidative RNA demethylase activity(GO:0035515)
0.3 0.7 GO:0051378 serotonin binding(GO:0051378)
0.2 0.6 GO:0030620 U2 snRNA binding(GO:0030620)
0.0 0.6 GO:0016863 intramolecular oxidoreductase activity, transposing C=C bonds(GO:0016863)
0.0 0.6 GO:0005234 extracellular-glutamate-gated ion channel activity(GO:0005234)
0.2 0.5 GO:0035727 lysophosphatidic acid binding(GO:0035727)
0.1 0.5 GO:0001972 retinoic acid binding(GO:0001972)
0.0 0.5 GO:0051010 microtubule plus-end binding(GO:0051010)
0.1 0.4 GO:0043495 protein anchor(GO:0043495)