Motif ID: Ppard

Z-value: 0.475


Transcription factors associated with Ppard:

Gene SymbolEntrez IDGene Name
Ppard ENSMUSG00000002250.9 Ppard

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Ppardmm10_v2_chr17_+_28272191_28272205-0.451.0e-01Click!


Activity profile for motif Ppard.

activity profile for motif Ppard


Sorted Z-values histogram for motif Ppard

Sorted Z-values for motif Ppard



Network of associatons between targets according to the STRING database.



First level regulatory network of Ppard

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr3_+_98280427 1.481 ENSMUST00000090746.2
ENSMUST00000120541.1
 Hmgcs2

3-hydroxy-3-methylglutaryl-Coenzyme A synthase 2

chr15_-_89425795 1.119 ENSMUST00000168376.1
 Cpt1b
carnitine palmitoyltransferase 1b, muscle
chr3_-_79628660 0.802 ENSMUST00000120992.1
 Etfdh
electron transferring flavoprotein, dehydrogenase
chr3_+_87948666 0.739 ENSMUST00000005019.5
 Crabp2
cellular retinoic acid binding protein II
chr17_-_34028044 0.657 ENSMUST00000045467.7
ENSMUST00000114303.3
 H2-Ke6

H2-K region expressed gene 6

chr15_-_89425856 0.656 ENSMUST00000109313.2
 Cpt1b
carnitine palmitoyltransferase 1b, muscle
chr1_+_178319130 0.620 ENSMUST00000027781.6
 Cox20
COX20 Cox2 chaperone
chrX_-_142306170 0.599 ENSMUST00000134825.2
 Kcne1l
potassium voltage-gated channel, Isk-related family, member 1-like, pseudogene
chr10_+_58255465 0.494 ENSMUST00000057659.7
ENSMUST00000162041.1
ENSMUST00000162860.1
 Gcc2


GRIP and coiled-coil domain containing 2


chr11_-_70015346 0.457 ENSMUST00000018718.7
ENSMUST00000102574.3
 Acadvl

acyl-Coenzyme A dehydrogenase, very long chain

chr11_-_4704334 0.450 ENSMUST00000058407.5
 Uqcr10
ubiquinol-cytochrome c reductase, complex III subunit X
chr5_-_115119277 0.449 ENSMUST00000031524.7
 Acads
acyl-Coenzyme A dehydrogenase, short chain
chr11_+_70657687 0.440 ENSMUST00000134087.1
ENSMUST00000170716.1
 Eno3

enolase 3, beta muscle

chr1_-_120120138 0.417 ENSMUST00000112648.1
ENSMUST00000128408.1
 Dbi

diazepam binding inhibitor

chr3_-_79628859 0.398 ENSMUST00000029386.7
 Etfdh
electron transferring flavoprotein, dehydrogenase
chr15_-_102189032 0.393 ENSMUST00000023805.1
 Csad
cysteine sulfinic acid decarboxylase
chr4_+_118429701 0.359 ENSMUST00000067896.3
 Elovl1
elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 1
chr14_+_75136326 0.349 ENSMUST00000145303.1
 Lcp1
lymphocyte cytosolic protein 1
chr4_+_59581563 0.304 ENSMUST00000030078.5
 Hsdl2
hydroxysteroid dehydrogenase like 2
chr4_+_148602527 0.298 ENSMUST00000105701.2
ENSMUST00000052060.6
 Masp2

mannan-binding lectin serine peptidase 2

chr10_-_13324160 0.296 ENSMUST00000105545.4
 Phactr2
phosphatase and actin regulator 2
chr9_-_51278540 0.289 ENSMUST00000114427.3
 Gm684
predicted gene 684
chr2_+_92375306 0.286 ENSMUST00000028650.8
 Pex16
peroxisomal biogenesis factor 16
chr5_-_110286159 0.277 ENSMUST00000031472.5
 Pxmp2
peroxisomal membrane protein 2
chr2_-_73911323 0.256 ENSMUST00000111996.1
ENSMUST00000018914.2
 Atp5g3

ATP synthase, H+ transporting, mitochondrial F0 complex, subunit C3 (subunit 9)

chr15_+_25773985 0.250 ENSMUST00000125667.1
 Myo10
myosin X
chr19_+_5460607 0.247 ENSMUST00000025847.5
 Fibp
fibroblast growth factor (acidic) intracellular binding protein
chr4_+_59581645 0.240 ENSMUST00000107528.1
 Hsdl2
hydroxysteroid dehydrogenase like 2
chr4_-_45108038 0.239 ENSMUST00000107809.2
ENSMUST00000107808.2
ENSMUST00000107807.1
ENSMUST00000107810.2
 Tomm5



translocase of outer mitochondrial membrane 5 homolog (yeast)



chr3_-_8923796 0.232 ENSMUST00000042148.5
 Mrps28
mitochondrial ribosomal protein S28
chr16_-_84835484 0.224 ENSMUST00000114191.1
 Atp5j
ATP synthase, H+ transporting, mitochondrial F0 complex, subunit F
chr9_-_109059711 0.222 ENSMUST00000061973.4
 Trex1
three prime repair exonuclease 1
chr10_+_128303322 0.218 ENSMUST00000005825.6
 Pan2
PAN2 polyA specific ribonuclease subunit homolog (S. cerevisiae)
chr2_-_32704123 0.208 ENSMUST00000127812.1
 Fpgs
folylpolyglutamyl synthetase
chr16_-_84835557 0.197 ENSMUST00000138279.1
ENSMUST00000023608.7
 Atp5j

ATP synthase, H+ transporting, mitochondrial F0 complex, subunit F

chr19_-_32061438 0.192 ENSMUST00000096119.4
 Asah2
N-acylsphingosine amidohydrolase 2
chr13_-_86046901 0.178 ENSMUST00000131011.1
 Cox7c
cytochrome c oxidase subunit VIIc
chr4_-_155043143 0.176 ENSMUST00000135665.2
 Plch2
phospholipase C, eta 2
chr1_+_171329376 0.174 ENSMUST00000111299.1
ENSMUST00000064950.4
 Dedd

death effector domain-containing

chr9_-_22002599 0.171 ENSMUST00000115336.2
ENSMUST00000044926.5
 Ccdc151

coiled-coil domain containing 151

chr8_+_71469186 0.154 ENSMUST00000124745.1
ENSMUST00000138892.1
ENSMUST00000147642.1
 Dda1


DET1 and DDB1 associated 1


chr9_+_46012810 0.153 ENSMUST00000126865.1
 Sik3
SIK family kinase 3
chr1_+_171329015 0.145 ENSMUST00000111300.1
 Dedd
death effector domain-containing
chr5_-_31697598 0.138 ENSMUST00000031018.7
 Rbks
ribokinase
chr5_+_31697960 0.131 ENSMUST00000114515.2
 Bre
brain and reproductive organ-expressed protein
chr18_-_36726730 0.128 ENSMUST00000061829.6
 Cd14
CD14 antigen
chr16_-_4624984 0.127 ENSMUST00000014445.6
 Pam16
presequence translocase-asssociated motor 16 homolog (S. cerevisiae)
chr15_-_50890396 0.127 ENSMUST00000185183.1
 Trps1
trichorhinophalangeal syndrome I (human)
chr8_+_117095854 0.126 ENSMUST00000034308.8
ENSMUST00000167370.1
ENSMUST00000176860.1
 Bcmo1


beta-carotene 15,15'-monooxygenase


chr5_+_31698050 0.125 ENSMUST00000114507.3
ENSMUST00000063813.4
ENSMUST00000071531.5
ENSMUST00000131995.1
 Bre



brain and reproductive organ-expressed protein



chr6_-_97459279 0.123 ENSMUST00000113359.1
 Frmd4b
FERM domain containing 4B
chr16_+_84835070 0.123 ENSMUST00000009120.7
 Gabpa
GA repeat binding protein, alpha
chr1_+_82724909 0.120 ENSMUST00000073025.5
ENSMUST00000161648.1
ENSMUST00000160786.1
ENSMUST00000162003.1
 Mff



mitochondrial fission factor



chr9_+_22003035 0.106 ENSMUST00000115331.2
ENSMUST00000003493.7
 Prkcsh

protein kinase C substrate 80K-H

chr5_+_31697665 0.102 ENSMUST00000080598.7
 Bre
brain and reproductive organ-expressed protein
chr15_-_27630644 0.092 ENSMUST00000059662.7
 Fam105b
family with sequence similarity 105, member B
chr3_+_90051630 0.089 ENSMUST00000159064.1
 4933434E20Rik
RIKEN cDNA 4933434E20 gene
chr9_+_118506226 0.087 ENSMUST00000084820.4
 Golga4
golgi autoantigen, golgin subfamily a, 4
chr6_+_125145235 0.082 ENSMUST00000119527.1
ENSMUST00000088276.6
ENSMUST00000051171.7
ENSMUST00000117675.1
 Iffo1



intermediate filament family orphan 1



chr5_+_110286306 0.078 ENSMUST00000007296.5
ENSMUST00000112482.1
 Pole

polymerase (DNA directed), epsilon

chr5_+_129725063 0.059 ENSMUST00000086046.3
 Gbas
glioblastoma amplified sequence
chr5_+_36464998 0.058 ENSMUST00000031099.3
 Grpel1
GrpE-like 1, mitochondrial
chr4_+_131873608 0.054 ENSMUST00000053819.3
 Srsf4
serine/arginine-rich splicing factor 4
chr9_-_57262591 0.041 ENSMUST00000034846.5
 1700017B05Rik
RIKEN cDNA 1700017B05 gene
chr1_+_55088132 0.038 ENSMUST00000075242.6
 Hspe1
heat shock protein 1 (chaperonin 10)
chr3_-_138131356 0.033 ENSMUST00000029805.8
 Mttp
microsomal triglyceride transfer protein
chr19_-_45998479 0.017 ENSMUST00000045396.7
 9130011E15Rik
RIKEN cDNA 9130011E15 gene
chr2_+_154436437 0.011 ENSMUST00000109725.1
ENSMUST00000099178.3
ENSMUST00000045270.8
ENSMUST00000109724.1
 Cbfa2t2



core-binding factor, runt domain, alpha subunit 2, translocated to, 2 (human)



chr19_+_4594312 0.010 ENSMUST00000113825.2
 Pcx
pyruvate carboxylase

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 GO:0099624 regulation of atrial cardiac muscle cell membrane repolarization(GO:0060372) atrial cardiac muscle cell membrane repolarization(GO:0099624)
0.1 0.7 GO:0006703 estrogen biosynthetic process(GO:0006703)
0.1 0.4 GO:0036151 phosphatidylcholine acyl-chain remodeling(GO:0036151)
0.1 2.0 GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
0.1 0.5 GO:0071955 recycling endosome to Golgi transport(GO:0071955)
0.1 0.4 GO:0000098 sulfur amino acid catabolic process(GO:0000098)
0.1 0.2 GO:0046900 tetrahydrofolylpolyglutamate metabolic process(GO:0046900)
0.1 1.5 GO:0008299 isoprenoid biosynthetic process(GO:0008299)
0.1 0.7 GO:0042573 retinoic acid metabolic process(GO:0042573) positive regulation of collateral sprouting(GO:0048672)
0.1 0.6 GO:0097034 mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
0.1 0.4 GO:0034551 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033)
0.1 0.3 GO:1901837 negative regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901837)
0.0 0.3 GO:0016557 peroxisome membrane biogenesis(GO:0016557)
0.0 0.4 GO:0019368 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.0 0.1 GO:0071726 response to diacyl bacterial lipopeptide(GO:0071724) cellular response to diacyl bacterial lipopeptide(GO:0071726)
0.0 1.8 GO:0015909 long-chain fatty acid transport(GO:0015909)
0.0 0.7 GO:0015985 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.0 0.3 GO:0071803 positive regulation of podosome assembly(GO:0071803)
0.0 0.1 GO:0019321 pentose metabolic process(GO:0019321)
0.0 0.1 GO:2000983 regulation of ATP citrate synthase activity(GO:2000983) negative regulation of ATP citrate synthase activity(GO:2000984)
0.0 0.2 GO:0036158 outer dynein arm assembly(GO:0036158)
0.0 0.0 GO:0034196 acylglycerol transport(GO:0034196) triglyceride transport(GO:0034197)
0.0 0.3 GO:0006958 complement activation, classical pathway(GO:0006958)
0.0 0.2 GO:0000291 nuclear-transcribed mRNA catabolic process, exonucleolytic(GO:0000291)
0.0 0.1 GO:0006287 base-excision repair, gap-filling(GO:0006287)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.1 GO:0045251 mitochondrial electron transfer flavoprotein complex(GO:0017133) electron transfer flavoprotein complex(GO:0045251)
0.1 0.4 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.1 0.2 GO:0031251 PAN complex(GO:0031251)
0.1 0.4 GO:0005750 mitochondrial respiratory chain complex III(GO:0005750)
0.0 0.7 GO:0045263 proton-transporting ATP synthase complex, coupling factor F(o)(GO:0045263)
0.0 0.4 GO:0070552 BRISC complex(GO:0070552)
0.0 0.2 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.0 0.1 GO:0031314 mitochondrial inner membrane presequence translocase complex(GO:0005744) extrinsic component of mitochondrial inner membrane(GO:0031314)
0.0 0.1 GO:0008622 epsilon DNA polymerase complex(GO:0008622)
0.0 0.4 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.0 0.3 GO:0001891 phagocytic cup(GO:0001891) podosome(GO:0002102)
0.0 3.3 GO:0005759 mitochondrial matrix(GO:0005759)
0.0 0.1 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.0 0.3 GO:0005779 integral component of peroxisomal membrane(GO:0005779)
0.0 1.7 GO:0005741 mitochondrial outer membrane(GO:0005741)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.2 GO:0048039 ubiquinone binding(GO:0048039)
0.4 1.8 GO:0004095 carnitine O-palmitoyltransferase activity(GO:0004095)
0.2 1.5 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.1 0.7 GO:0019841 retinol binding(GO:0019841)
0.1 0.6 GO:0086008 voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization(GO:0086008)
0.1 0.4 GO:0030156 benzodiazepine receptor binding(GO:0030156)
0.1 0.7 GO:0004303 estradiol 17-beta-dehydrogenase activity(GO:0004303)
0.1 0.5 GO:0017099 very-long-chain-acyl-CoA dehydrogenase activity(GO:0017099)
0.1 0.4 GO:0008121 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors(GO:0016679) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.1 0.2 GO:0008853 exodeoxyribonuclease III activity(GO:0008853)
0.0 0.4 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.0 0.4 GO:0052890 acyl-CoA dehydrogenase activity(GO:0003995) oxidoreductase activity, acting on the CH-CH group of donors, with a flavin as acceptor(GO:0052890)
0.0 0.4 GO:0102338 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.0 0.2 GO:0017040 ceramidase activity(GO:0017040)
0.0 0.1 GO:0070891 lipoteichoic acid binding(GO:0070891)
0.0 0.3 GO:0001846 opsonin binding(GO:0001846)
0.0 0.5 GO:0008748 N-ethylmaleimide reductase activity(GO:0008748) reduced coenzyme F420 dehydrogenase activity(GO:0043738) sulfur oxygenase reductase activity(GO:0043826) malolactic enzyme activity(GO:0043883) epoxyqueuosine reductase activity(GO:0052693)
0.0 0.4 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 0.2 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.0 0.1 GO:1990825 sequence-specific mRNA binding(GO:1990825)