Motif ID: Pparg_Rxrg

Z-value: 0.799

Transcription factors associated with Pparg_Rxrg:

Gene SymbolEntrez IDGene Name
Pparg ENSMUSG00000000440.6 Pparg
Rxrg ENSMUSG00000015843.4 Rxrg

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Rxrgmm10_v2_chr1_+_167618246_1676183090.714.7e-03Click!


Activity profile for motif Pparg_Rxrg.

activity profile for motif Pparg_Rxrg


Sorted Z-values histogram for motif Pparg_Rxrg

Sorted Z-values for motif Pparg_Rxrg



Network of associatons between targets according to the STRING database.



First level regulatory network of Pparg_Rxrg

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr11_-_77894096 1.653 ENSMUST00000017597.4
 Pipox
pipecolic acid oxidase
chr19_+_36554661 1.562 ENSMUST00000169036.2
ENSMUST00000047247.5
 Hectd2

HECT domain containing 2

chr3_+_94693556 1.451 ENSMUST00000090848.3
ENSMUST00000173981.1
ENSMUST00000173849.1
ENSMUST00000174223.1
 Selenbp2



selenium binding protein 2



chr2_-_79456750 1.443 ENSMUST00000041099.4
 Neurod1
neurogenic differentiation 1
chr2_-_180104463 1.396 ENSMUST00000056480.3
 Hrh3
histamine receptor H3
chr11_-_100759942 1.275 ENSMUST00000107363.2
 Kcnh4
potassium voltage-gated channel, subfamily H (eag-related), member 4
chrX_+_10485121 1.207 ENSMUST00000076354.6
ENSMUST00000115526.1
 Tspan7

tetraspanin 7

chr11_-_100354040 1.148 ENSMUST00000173630.1
 Hap1
huntingtin-associated protein 1
chr3_-_79628660 1.105 ENSMUST00000120992.1
 Etfdh
electron transferring flavoprotein, dehydrogenase
chr10_+_112271123 1.044 ENSMUST00000092175.2
 Kcnc2
potassium voltage gated channel, Shaw-related subfamily, member 2
chr15_+_3270767 1.014 ENSMUST00000082424.4
ENSMUST00000159158.1
ENSMUST00000159216.1
ENSMUST00000160311.1
 Sepp1



selenoprotein P, plasma, 1



chr3_-_55055038 0.954 ENSMUST00000029368.2
 Ccna1
cyclin A1
chrX_-_109013389 0.916 ENSMUST00000033597.8
 Hmgn5
high-mobility group nucleosome binding domain 5
chr11_-_70015346 0.821 ENSMUST00000018718.7
ENSMUST00000102574.3
 Acadvl

acyl-Coenzyme A dehydrogenase, very long chain

chr11_-_118401826 0.814 ENSMUST00000106290.3
ENSMUST00000043722.3
 Lgals3bp

lectin, galactoside-binding, soluble, 3 binding protein

chr4_-_139092958 0.806 ENSMUST00000042844.6
 Nbl1
neuroblastoma, suppression of tumorigenicity 1
chr17_-_34028044 0.805 ENSMUST00000045467.7
ENSMUST00000114303.3
 H2-Ke6

H2-K region expressed gene 6

chr12_-_100899436 0.804 ENSMUST00000053668.3
 Gpr68
G protein-coupled receptor 68
chr6_-_83156393 0.795 ENSMUST00000153148.1
ENSMUST00000125894.1
 Wdr54

WD repeat domain 54

chr11_+_116593687 0.791 ENSMUST00000153476.1
 Aanat
arylalkylamine N-acetyltransferase

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 226 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.6 1.7 GO:0006553 lysine metabolic process(GO:0006553)
0.1 1.6 GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
0.5 1.4 GO:0014063 negative regulation of serotonin secretion(GO:0014063)
0.4 1.4 GO:0060729 intestinal epithelial structure maintenance(GO:0060729)
0.1 1.2 GO:0042760 very long-chain fatty acid catabolic process(GO:0042760)
0.3 1.1 GO:0032901 positive regulation of neurotrophin production(GO:0032901)
0.2 1.1 GO:0010624 regulation of Schwann cell proliferation(GO:0010624)
0.0 1.1 GO:0015909 long-chain fatty acid transport(GO:0015909)
0.1 1.0 GO:0001887 selenium compound metabolic process(GO:0001887)
0.1 1.0 GO:0071732 cellular response to nitric oxide(GO:0071732)
0.3 0.9 GO:0001803 type III hypersensitivity(GO:0001802) regulation of type III hypersensitivity(GO:0001803) positive regulation of type III hypersensitivity(GO:0001805)
0.3 0.8 GO:1904685 positive regulation of metalloendopeptidase activity(GO:1904685)
0.3 0.8 GO:0035582 sequestering of BMP in extracellular matrix(GO:0035582)
0.3 0.8 GO:2001206 positive regulation of osteoclast development(GO:2001206)
0.2 0.8 GO:0015788 UDP-N-acetylglucosamine transport(GO:0015788)
0.2 0.8 GO:0051365 cellular response to potassium ion starvation(GO:0051365)
0.1 0.8 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
0.1 0.8 GO:0006703 estrogen biosynthetic process(GO:0006703)
0.1 0.8 GO:0042435 indole-containing compound biosynthetic process(GO:0042435)
0.1 0.8 GO:1904294 positive regulation of ERAD pathway(GO:1904294)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 85 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 1.8 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.3 1.2 GO:0045251 mitochondrial electron transfer flavoprotein complex(GO:0017133) electron transfer flavoprotein complex(GO:0045251)
0.0 1.2 GO:0016234 inclusion body(GO:0016234)
0.3 1.0 GO:0097450 astrocyte end-foot(GO:0097450)
0.0 1.0 GO:0032809 neuronal cell body membrane(GO:0032809)
0.1 0.8 GO:0044327 dendritic spine head(GO:0044327)
0.0 0.8 GO:0030665 clathrin-coated vesicle membrane(GO:0030665)
0.2 0.7 GO:0043512 inhibin-betaglycan-ActRII complex(GO:0034673) inhibin A complex(GO:0043512)
0.1 0.7 GO:0070552 BRISC complex(GO:0070552)
0.1 0.7 GO:0001739 sex chromatin(GO:0001739)
0.1 0.6 GO:0005638 lamin filament(GO:0005638)
0.0 0.6 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.0 0.6 GO:0072562 blood microparticle(GO:0072562)
0.0 0.6 GO:0031526 brush border membrane(GO:0031526)
0.1 0.5 GO:0016035 zeta DNA polymerase complex(GO:0016035)
0.0 0.5 GO:0030057 desmosome(GO:0030057)
0.0 0.5 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.0 0.5 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.0 0.5 GO:0060170 ciliary membrane(GO:0060170)
0.1 0.4 GO:0005595 collagen type XII trimer(GO:0005595) anchoring collagen complex(GO:0030934)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 162 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 3.1 GO:0008430 selenium binding(GO:0008430)
0.0 1.9 GO:0070888 E-box binding(GO:0070888)
0.4 1.7 GO:0016647 oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647)
0.5 1.6 GO:0048039 ubiquinone binding(GO:0048039)
0.0 1.6 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.2 1.2 GO:0004095 carnitine O-palmitoyltransferase activity(GO:0004095)
0.2 1.2 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.2 1.2 GO:0004466 long-chain-acyl-CoA dehydrogenase activity(GO:0004466)
0.0 1.2 GO:0071889 14-3-3 protein binding(GO:0071889)
0.0 1.2 GO:0070491 repressing transcription factor binding(GO:0070491)
0.2 1.1 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)
0.0 1.0 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.2 0.9 GO:0019763 immunoglobulin receptor activity(GO:0019763)
0.2 0.9 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.0 0.9 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.2 0.8 GO:0008392 arachidonic acid monooxygenase activity(GO:0008391) arachidonic acid epoxygenase activity(GO:0008392)
0.1 0.8 GO:0048403 brain-derived neurotrophic factor binding(GO:0048403)
0.1 0.8 GO:0016500 protein-hormone receptor activity(GO:0016500)
0.0 0.8 GO:0070300 phosphatidic acid binding(GO:0070300)
0.0 0.8 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)