Motif ID: Prop1

Z-value: 1.500


Transcription factors associated with Prop1:

Gene SymbolEntrez IDGene Name
Prop1 ENSMUSG00000044542.3 Prop1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Prop1mm10_v2_chr11_-_50953745_509537680.312.8e-01Click!


Activity profile for motif Prop1.

activity profile for motif Prop1


Sorted Z-values histogram for motif Prop1

Sorted Z-values for motif Prop1



Network of associatons between targets according to the STRING database.



First level regulatory network of Prop1

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image


Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr10_-_64090241 15.098 ENSMUST00000133588.1
Lrrtm3
leucine rich repeat transmembrane neuronal 3
chr18_-_66860458 15.064 ENSMUST00000057942.2
Mc4r
melanocortin 4 receptor
chr10_-_64090265 10.629 ENSMUST00000105439.1
Lrrtm3
leucine rich repeat transmembrane neuronal 3
chr18_-_13972617 8.695 ENSMUST00000025288.7
Zfp521
zinc finger protein 521
chr9_+_118478182 6.176 ENSMUST00000111763.1
Eomes
eomesodermin homolog (Xenopus laevis)
chr9_+_118478344 5.673 ENSMUST00000035020.8
Eomes
eomesodermin homolog (Xenopus laevis)
chr4_+_102430047 4.143 ENSMUST00000172616.1
Pde4b
phosphodiesterase 4B, cAMP specific
chr19_-_19001099 3.809 ENSMUST00000040153.8
ENSMUST00000112828.1
Rorb

RAR-related orphan receptor beta

chr6_-_136173492 3.445 ENSMUST00000111905.1
Grin2b
glutamate receptor, ionotropic, NMDA2B (epsilon 2)
chr14_+_75455957 3.422 ENSMUST00000164848.1
Siah3
seven in absentia homolog 3 (Drosophila)
chr4_-_82505707 3.355 ENSMUST00000107248.1
ENSMUST00000107247.1
Nfib

nuclear factor I/B

chr10_-_45470201 3.255 ENSMUST00000079390.6
Lin28b
lin-28 homolog B (C. elegans)
chr2_+_61804453 3.031 ENSMUST00000048934.8
Tbr1
T-box brain gene 1
chr16_-_16829276 2.815 ENSMUST00000023468.5
Spag6
sperm associated antigen 6
chr4_-_119492563 2.662 ENSMUST00000049994.7
Rimkla
ribosomal modification protein rimK-like family member A
chr8_-_85690973 2.606 ENSMUST00000109686.3
Neto2
neuropilin (NRP) and tolloid (TLL)-like 2
chr14_+_74640840 2.535 ENSMUST00000036653.3
Htr2a
5-hydroxytryptamine (serotonin) receptor 2A
chr6_+_58831748 2.472 ENSMUST00000126292.1
ENSMUST00000031823.5
Herc3

hect domain and RLD 3

chr4_+_47386216 2.449 ENSMUST00000107725.2
Tgfbr1
transforming growth factor, beta receptor I
chr12_-_55014329 2.293 ENSMUST00000172875.1
Baz1a
bromodomain adjacent to zinc finger domain 1A

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 92 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.7 25.7 GO:1902993 positive regulation of beta-amyloid formation(GO:1902004) positive regulation of amyloid precursor protein catabolic process(GO:1902993)
3.0 15.1 GO:0002024 diet induced thermogenesis(GO:0002024) adaptive thermogenesis(GO:1990845)
3.9 11.8 GO:0002302 CD8-positive, alpha-beta T cell differentiation involved in immune response(GO:0002302)
1.4 5.4 GO:2000795 negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.4 5.2 GO:1901898 negative regulation of relaxation of muscle(GO:1901078) negative regulation of relaxation of cardiac muscle(GO:1901898)
0.4 4.7 GO:0010650 positive regulation of cell communication by electrical coupling(GO:0010650) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.1 4.2 GO:0006284 base-excision repair(GO:0006284)
0.6 3.8 GO:0046549 retinal cone cell development(GO:0046549)
0.7 3.4 GO:1903215 negative regulation of protein targeting to mitochondrion(GO:1903215)
0.2 3.4 GO:0050966 detection of mechanical stimulus involved in sensory perception of pain(GO:0050966)
0.4 3.3 GO:0010587 miRNA catabolic process(GO:0010587)
0.6 3.0 GO:0001661 conditioned taste aversion(GO:0001661) amygdala development(GO:0021764)
0.1 2.9 GO:1900449 regulation of glutamate receptor signaling pathway(GO:1900449)
0.0 2.8 GO:0042787 protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0042787)
0.8 2.5 GO:0007210 serotonin receptor signaling pathway(GO:0007210)
0.4 2.4 GO:0060017 parathyroid gland development(GO:0060017)
0.5 2.3 GO:0060467 negative regulation of fertilization(GO:0060467)
0.2 2.1 GO:0006020 inositol metabolic process(GO:0006020)
0.3 2.0 GO:0007197 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197) phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway(GO:0007207)
0.3 2.0 GO:1903056 regulation of lens fiber cell differentiation(GO:1902746) positive regulation of lens fiber cell differentiation(GO:1902748) regulation of melanosome organization(GO:1903056)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 51 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 27.5 GO:0045211 postsynaptic membrane(GO:0045211)
0.3 5.4 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.8 5.3 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
0.2 4.7 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.2 4.1 GO:0000930 gamma-tubulin complex(GO:0000930)
0.3 3.4 GO:0043083 synaptic cleft(GO:0043083)
0.0 3.0 GO:0001669 acrosomal vesicle(GO:0001669)
0.0 2.6 GO:0014069 postsynaptic density(GO:0014069) postsynaptic specialization(GO:0099572)
0.2 2.5 GO:0070852 cell body fiber(GO:0070852)
0.0 2.4 GO:0043235 receptor complex(GO:0043235)
0.5 2.3 GO:0008623 CHRAC(GO:0008623)
0.1 1.9 GO:0031045 dense core granule(GO:0031045)
0.1 1.7 GO:0016580 Sin3 complex(GO:0016580)
0.5 1.6 GO:0035061 interchromatin granule(GO:0035061)
0.1 1.6 GO:0005721 pericentric heterochromatin(GO:0005721)
0.0 1.6 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 1.6 GO:0005925 focal adhesion(GO:0005925)
0.0 1.5 GO:0030424 axon(GO:0030424)
0.1 1.4 GO:0001891 phagocytic cup(GO:0001891)
0.2 1.3 GO:0045179 apical cortex(GO:0045179)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 73 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 25.7 GO:0004860 protein kinase inhibitor activity(GO:0004860)
5.0 15.1 GO:0004980 melanocortin receptor activity(GO:0004977) melanocyte-stimulating hormone receptor activity(GO:0004980)
0.2 13.1 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.0 6.7 GO:0019904 protein domain specific binding(GO:0019904)
0.0 6.2 GO:0004842 ubiquitin-protein transferase activity(GO:0004842)
0.6 5.8 GO:0051575 5'-deoxyribose-5-phosphate lyase activity(GO:0051575)
0.2 5.2 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.2 4.7 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.1 4.1 GO:0030552 cAMP binding(GO:0030552)
0.1 4.0 GO:0035255 ionotropic glutamate receptor binding(GO:0035255)
1.3 3.8 GO:0008502 melatonin receptor activity(GO:0008502)
0.4 3.5 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.3 3.4 GO:0031749 D2 dopamine receptor binding(GO:0031749)
0.0 3.0 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.0 2.7 GO:0016879 ligase activity, forming carbon-nitrogen bonds(GO:0016879)
0.6 2.5 GO:0004993 G-protein coupled serotonin receptor activity(GO:0004993) serotonin binding(GO:0051378) serotonin receptor activity(GO:0099589)
0.7 2.1 GO:0031403 lithium ion binding(GO:0031403)
0.7 2.0 GO:0016934 extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.1 2.0 GO:0070412 R-SMAD binding(GO:0070412)
0.0 2.0 GO:0008565 protein transporter activity(GO:0008565)