Motif ID: Rara

Z-value: 0.498


Transcription factors associated with Rara:

Gene SymbolEntrez IDGene Name
Rara ENSMUSG00000037992.10 Rara

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Raramm10_v2_chr11_+_98960412_98960485-0.224.5e-01Click!


Activity profile for motif Rara.

activity profile for motif Rara


Sorted Z-values histogram for motif Rara

Sorted Z-values for motif Rara



Network of associatons between targets according to the STRING database.



First level regulatory network of Rara

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr4_-_141599835 0.742 ENSMUST00000141518.1
ENSMUST00000127455.1
ENSMUST00000105784.1
ENSMUST00000147785.1
 Fblim1



filamin binding LIM protein 1



chr6_+_114131229 0.724 ENSMUST00000032451.7
 Slc6a11
solute carrier family 6 (neurotransmitter transporter, GABA), member 11
chr1_-_175692624 0.441 ENSMUST00000027809.7
 Opn3
opsin 3
chr3_-_54915867 0.408 ENSMUST00000070342.3
 Sertm1
serine rich and transmembrane domain containing 1
chr6_+_30723541 0.402 ENSMUST00000115127.1
 Mest
mesoderm specific transcript
chr1_+_134037490 0.401 ENSMUST00000162779.1
 Fmod
fibromodulin
chr10_+_21993890 0.386 ENSMUST00000092673.4
 Sgk1
serum/glucocorticoid regulated kinase 1
chrX_-_59567348 0.379 ENSMUST00000124402.1
 Fgf13
fibroblast growth factor 13
chr10_+_4611971 0.326 ENSMUST00000105590.1
ENSMUST00000067086.7
 Esr1

estrogen receptor 1 (alpha)

chr2_+_169633517 0.256 ENSMUST00000109157.1
 Tshz2
teashirt zinc finger family member 2
chr13_+_94875600 0.256 ENSMUST00000022195.10
 Otp
orthopedia homolog (Drosophila)
chr6_+_18848571 0.255 ENSMUST00000056398.8
 Naa38
N(alpha)-acetyltransferase 38, NatC auxiliary subunit
chr4_-_46991842 0.223 ENSMUST00000107749.2
 Gabbr2
gamma-aminobutyric acid (GABA) B receptor, 2
chr14_+_76488436 0.206 ENSMUST00000101618.2
 Tsc22d1
TSC22 domain family, member 1
chr12_-_108893197 0.197 ENSMUST00000161154.1
ENSMUST00000161410.1
 Wars

tryptophanyl-tRNA synthetase

chrX_+_74254736 0.185 ENSMUST00000096424.4
 Emd
emerin
chrX_+_106187100 0.179 ENSMUST00000081593.6
 Pgk1
phosphoglycerate kinase 1
chr11_+_94629741 0.170 ENSMUST00000021239.6
 Lrrc59
leucine rich repeat containing 59
chr14_+_58070547 0.166 ENSMUST00000165526.1
 Fgf9
fibroblast growth factor 9
chr14_-_70207637 0.163 ENSMUST00000022682.5
 Sorbs3
sorbin and SH3 domain containing 3
chr7_+_120635176 0.162 ENSMUST00000033176.5
 Uqcrc2
ubiquinol cytochrome c reductase core protein 2
chr4_+_150853919 0.158 ENSMUST00000073600.2
 Errfi1
ERBB receptor feedback inhibitor 1
chr6_-_54972603 0.148 ENSMUST00000060655.8
 Nod1
nucleotide-binding oligomerization domain containing 1
chr14_-_16575456 0.147 ENSMUST00000063750.6
 Rarb
retinoic acid receptor, beta
chr11_+_4986824 0.146 ENSMUST00000009234.9
ENSMUST00000109897.1
 Ap1b1

adaptor protein complex AP-1, beta 1 subunit

chr6_+_115601907 0.144 ENSMUST00000000449.7
 Mkrn2
makorin, ring finger protein, 2
chr4_+_32238950 0.126 ENSMUST00000037416.6
 Bach2
BTB and CNC homology 2
chr7_-_141429351 0.119 ENSMUST00000164387.1
ENSMUST00000137488.1
ENSMUST00000084436.3
 Cend1


cell cycle exit and neuronal differentiation 1


chr7_+_45873127 0.118 ENSMUST00000107718.1
 Kdelr1
KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1
chr7_+_45872772 0.118 ENSMUST00000002855.5
ENSMUST00000107719.1
 Kdelr1

KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1

chr3_-_88058446 0.112 ENSMUST00000029708.6
 Apoa1bp
apolipoprotein A-I binding protein
chr3_+_79884576 0.109 ENSMUST00000145992.1
 Fam198b
family with sequence similarity 198, member B
chr6_-_6217023 0.098 ENSMUST00000015256.8
 Slc25a13
solute carrier family 25 (mitochondrial carrier, adenine nucleotide translocator), member 13
chr3_-_75556759 0.096 ENSMUST00000162138.1
ENSMUST00000029424.5
ENSMUST00000161137.1
 Pdcd10


programmed cell death 10


chr2_+_120977017 0.092 ENSMUST00000067582.7
 Tmem62
transmembrane protein 62
chr8_-_94876269 0.090 ENSMUST00000046461.7
 Dok4
docking protein 4
chr17_-_56133817 0.087 ENSMUST00000167545.1
 Sema6b
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6B
chrX_+_74254782 0.081 ENSMUST00000119197.1
ENSMUST00000088313.4
 Emd

emerin

chr2_-_181365306 0.080 ENSMUST00000108808.1
ENSMUST00000170190.1
ENSMUST00000127988.1
 Arfrp1


ADP-ribosylation factor related protein 1


chr4_-_128609981 0.077 ENSMUST00000141040.1
ENSMUST00000147876.1
ENSMUST00000097877.2
 Zscan20


zinc finger and SCAN domains 20


chr9_-_109074049 0.076 ENSMUST00000161521.1
ENSMUST00000045011.2
 Atrip

ATR interacting protein

chr2_+_26319741 0.074 ENSMUST00000066889.6
 Gpsm1
G-protein signalling modulator 1 (AGS3-like, C. elegans)
chr8_+_11556061 0.066 ENSMUST00000054399.4
 Ing1
inhibitor of growth family, member 1
chr3_+_79884496 0.065 ENSMUST00000118853.1
 Fam198b
family with sequence similarity 198, member B
chr2_+_5845243 0.058 ENSMUST00000127116.1
 Nudt5
nudix (nucleoside diphosphate linked moiety X)-type motif 5
chr5_+_53590215 0.058 ENSMUST00000037618.6
 Rbpj
recombination signal binding protein for immunoglobulin kappa J region
chr5_-_105239533 0.058 ENSMUST00000065588.6
 Gbp10
guanylate-binding protein 10
chr7_-_141429433 0.058 ENSMUST00000124444.1
 Cend1
cell cycle exit and neuronal differentiation 1
chr4_+_41348996 0.057 ENSMUST00000072866.5
ENSMUST00000108060.3
 Ubap1

ubiquitin-associated protein 1

chr15_+_82256023 0.056 ENSMUST00000143238.1
 1500009C09Rik
RIKEN cDNA 1500009C09 gene
chr6_-_39810881 0.053 ENSMUST00000114797.1
ENSMUST00000031978.8
 Mrps33

mitochondrial ribosomal protein S33

chr3_-_36475688 0.052 ENSMUST00000029266.8
 Anxa5
annexin A5
chr8_-_119778380 0.051 ENSMUST00000049156.5
 Tldc1
TBC/LysM associated domain containing 1
chr11_-_50953745 0.049 ENSMUST00000162420.1
ENSMUST00000051159.2
 Prop1

paired like homeodomain factor 1

chr10_+_79910856 0.042 ENSMUST00000181321.1
 Gm26602
predicted gene, 26602
chr10_-_89257790 0.039 ENSMUST00000045601.7
 Ano4
anoctamin 4
chr5_+_138255608 0.038 ENSMUST00000062067.6
 Lamtor4
late endosomal/lysosomal adaptor, MAPK and MTOR activator 4
chr5_+_53267103 0.028 ENSMUST00000121042.1
 Smim20
small integral membrane protein 20
chr8_+_69659263 0.028 ENSMUST00000169125.1
 Zfp964
zinc finger protein 964
chr2_-_34754364 0.024 ENSMUST00000142436.1
ENSMUST00000113099.3
ENSMUST00000028224.8
 Gapvd1


GTPase activating protein and VPS9 domains 1


chr10_+_19951055 0.024 ENSMUST00000152533.1
 Map3k5
mitogen-activated protein kinase kinase kinase 5
chr9_-_83146601 0.022 ENSMUST00000162246.2
ENSMUST00000161796.2
 Hmgn3

high mobility group nucleosomal binding domain 3

chr2_-_91070180 0.020 ENSMUST00000153367.1
ENSMUST00000079976.3
 Slc39a13

solute carrier family 39 (metal ion transporter), member 13

chr9_-_43105718 0.018 ENSMUST00000165665.1
 Arhgef12
Rho guanine nucleotide exchange factor (GEF) 12
chr3_-_95015214 0.015 ENSMUST00000128438.1
ENSMUST00000149747.1
ENSMUST00000019482.1
 Zfp687


zinc finger protein 687


chr4_+_141444654 0.012 ENSMUST00000006377.6
 Zbtb17
zinc finger and BTB domain containing 17
chr2_+_131262469 0.010 ENSMUST00000150843.1
 Pank2
pantothenate kinase 2
chr6_+_91157373 0.007 ENSMUST00000155007.1
 Hdac11
histone deacetylase 11
chr8_+_106150359 0.000 ENSMUST00000034377.6
 Pla2g15
phospholipase A2, group XV

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0018298 protein-chromophore linkage(GO:0018298)
0.1 0.3 GO:0060745 mammary gland branching involved in pregnancy(GO:0060745)
0.1 0.2 GO:0006436 tryptophanyl-tRNA aminoacylation(GO:0006436)
0.1 0.2 GO:0021933 radial glia guided migration of cerebellar granule cell(GO:0021933)
0.1 0.4 GO:0045200 establishment or maintenance of neuroblast polarity(GO:0045196) establishment of neuroblast polarity(GO:0045200)
0.1 0.7 GO:0033623 regulation of integrin activation(GO:0033623)
0.1 0.2 GO:0042536 negative regulation of tumor necrosis factor biosynthetic process(GO:0042536)
0.0 0.1 GO:0002606 positive regulation of dendritic cell antigen processing and presentation(GO:0002606)
0.0 0.7 GO:0015812 gamma-aminobutyric acid transport(GO:0015812)
0.0 0.2 GO:0006621 protein retention in ER lumen(GO:0006621)
0.0 0.1 GO:0003406 retinal pigment epithelium development(GO:0003406)
0.0 0.1 GO:0072554 blood vessel lumenization(GO:0072554)
0.0 0.4 GO:0043402 glucocorticoid mediated signaling pathway(GO:0043402)
0.0 0.1 GO:0043490 malate-aspartate shuttle(GO:0043490)
0.0 0.0 GO:0060126 somatotropin secreting cell differentiation(GO:0060126)
0.0 0.1 GO:1903587 regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903587)
0.0 0.3 GO:0021979 hypothalamus cell differentiation(GO:0021979)
0.0 0.2 GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.0 0.4 GO:0010883 regulation of lipid storage(GO:0010883)
0.0 0.3 GO:0035414 negative regulation of catenin import into nucleus(GO:0035414)
0.0 0.1 GO:0097211 prolactin secretion(GO:0070459) response to gonadotropin-releasing hormone(GO:0097210) cellular response to gonadotropin-releasing hormone(GO:0097211)
0.0 0.0 GO:0061588 calcium activated phospholipid scrambling(GO:0061588) calcium activated phosphatidylserine scrambling(GO:0061589) calcium activated phosphatidylcholine scrambling(GO:0061590) calcium activated galactosylceramide scrambling(GO:0061591)
0.0 0.2 GO:0003214 cardiac left ventricle morphogenesis(GO:0003214) male sex determination(GO:0030238) lung-associated mesenchyme development(GO:0060484)
0.0 0.2 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.0 0.4 GO:0030199 collagen fibril organization(GO:0030199)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0031417 NatC complex(GO:0031417)
0.0 0.2 GO:0038039 G-protein coupled receptor heterodimeric complex(GO:0038039)
0.0 0.2 GO:0005750 mitochondrial respiratory chain complex III(GO:0005750)
0.0 0.3 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.0 0.3 GO:0005652 nuclear lamina(GO:0005652)
0.0 0.1 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
0.1 0.4 GO:0009881 photoreceptor activity(GO:0009881)
0.1 0.3 GO:0031798 type 1 metabotropic glutamate receptor binding(GO:0031798) RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding(GO:0038052)
0.1 0.2 GO:0004830 tryptophan-tRNA ligase activity(GO:0004830)
0.1 0.2 GO:0046923 ER retention sequence binding(GO:0046923)
0.0 0.4 GO:0043423 3-phosphoinositide-dependent protein kinase binding(GO:0043423)
0.0 0.7 GO:0031005 filamin binding(GO:0031005)
0.0 0.2 GO:0016774 phosphotransferase activity, carboxyl group as acceptor(GO:0016774)
0.0 0.2 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.0 0.1 GO:0050700 CARD domain binding(GO:0050700)
0.0 0.1 GO:0015183 L-aspartate transmembrane transporter activity(GO:0015183)
0.0 0.6 GO:0048487 beta-tubulin binding(GO:0048487)
0.0 0.1 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.0 0.4 GO:0052771 coenzyme F390-A hydrolase activity(GO:0052770) coenzyme F390-G hydrolase activity(GO:0052771)