Motif ID: Relb

Z-value: 0.649


Transcription factors associated with Relb:

Gene SymbolEntrez IDGene Name
Relb ENSMUSG00000002983.10 Relb

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Relbmm10_v2_chr7_-_19629355_196294510.732.9e-03Click!


Activity profile for motif Relb.

activity profile for motif Relb


Sorted Z-values histogram for motif Relb

Sorted Z-values for motif Relb



Network of associatons between targets according to the STRING database.



First level regulatory network of Relb

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr4_+_130915949 1.982 ENSMUST00000030316.6
 Laptm5
lysosomal-associated protein transmembrane 5
chr8_+_72319033 1.753 ENSMUST00000067912.7
 Klf2
Kruppel-like factor 2 (lung)
chr1_-_171196229 1.693 ENSMUST00000111332.1
 Pcp4l1
Purkinje cell protein 4-like 1
chr7_-_19629355 1.661 ENSMUST00000049912.8
ENSMUST00000094762.3
ENSMUST00000098754.4
 Relb


avian reticuloendotheliosis viral (v-rel) oncogene related B


chr2_-_5063996 1.306 ENSMUST00000114996.1
 Optn
optineurin
chr2_-_5063932 1.266 ENSMUST00000027986.4
 Optn
optineurin
chrX_+_36112110 1.262 ENSMUST00000033418.7
 Il13ra1
interleukin 13 receptor, alpha 1
chr11_+_90030295 1.253 ENSMUST00000092788.3
 Tmem100
transmembrane protein 100
chr15_-_79164477 1.211 ENSMUST00000040019.4
 Sox10
SRY-box containing gene 10
chr14_+_60732906 1.183 ENSMUST00000162945.1
 Spata13
spermatogenesis associated 13
chr2_+_10153563 1.117 ENSMUST00000026886.7
 Itih5
inter-alpha (globulin) inhibitor H5
chr5_+_33658123 0.952 ENSMUST00000074849.6
ENSMUST00000079534.4
 Tacc3

transforming, acidic coiled-coil containing protein 3

chr12_-_55492587 0.729 ENSMUST00000021413.7
 Nfkbia
nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, alpha
chr4_+_99715640 0.718 ENSMUST00000097961.2
ENSMUST00000107004.2
ENSMUST00000139799.1
 Alg6


asparagine-linked glycosylation 6 (alpha-1,3,-glucosyltransferase)


chr7_-_102250086 0.702 ENSMUST00000106923.1
ENSMUST00000098230.4
 Rhog

ras homolog gene family, member G

chr4_+_129985098 0.667 ENSMUST00000106017.1
ENSMUST00000121049.1
 Bai2

brain-specific angiogenesis inhibitor 2

chr7_-_45920830 0.638 ENSMUST00000164119.1
 Emp3
epithelial membrane protein 3
chr8_+_46739745 0.631 ENSMUST00000034041.7
 Irf2
interferon regulatory factor 2
chr4_+_129984833 0.591 ENSMUST00000120204.1
 Bai2
brain-specific angiogenesis inhibitor 2
chr5_+_90891234 0.518 ENSMUST00000031327.8
 Cxcl1
chemokine (C-X-C motif) ligand 1
chr10_-_93310963 0.499 ENSMUST00000151153.1
 Elk3
ELK3, member of ETS oncogene family
chr9_+_64385626 0.473 ENSMUST00000093829.2
ENSMUST00000118485.1
ENSMUST00000164113.1
 Megf11


multiple EGF-like-domains 11


chr18_+_37484955 0.451 ENSMUST00000053856.4
 Pcdhb17
protocadherin beta 17
chr4_-_40239779 0.443 ENSMUST00000037907.6
 Ddx58
DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
chr19_+_46304709 0.440 ENSMUST00000073116.5
 Nfkb2
nuclear factor of kappa light polypeptide gene enhancer in B cells 2, p49/p100
chr3_-_9610074 0.413 ENSMUST00000041124.7
 Zfp704
zinc finger protein 704
chr7_-_99626936 0.412 ENSMUST00000178124.1
 Gm4980
predicted gene 4980
chr2_+_18672384 0.399 ENSMUST00000171845.1
ENSMUST00000061158.4
 Commd3

COMM domain containing 3

chr9_+_64385675 0.381 ENSMUST00000068967.4
 Megf11
multiple EGF-like-domains 11
chr10_-_93311073 0.376 ENSMUST00000008542.5
 Elk3
ELK3, member of ETS oncogene family
chr7_+_99535439 0.339 ENSMUST00000098266.2
ENSMUST00000179755.1
 Arrb1

arrestin, beta 1

chrX_+_141475385 0.325 ENSMUST00000112931.1
ENSMUST00000112930.1
 Col4a5

collagen, type IV, alpha 5

chr3_+_24333046 0.290 ENSMUST00000077389.6
 Gm7536
predicted gene 7536
chr4_+_129820198 0.253 ENSMUST00000030578.7
 Ptp4a2
protein tyrosine phosphatase 4a2
chr4_-_148500449 0.250 ENSMUST00000030840.3
 Angptl7
angiopoietin-like 7
chr13_-_8940977 0.241 ENSMUST00000071184.2
 Rpl10a-ps2
ribosomal protein L10A, pseudogene 2
chr15_-_89429093 0.213 ENSMUST00000170460.1
 Chkb
choline kinase beta
chr16_+_97997313 0.200 ENSMUST00000122450.1
 B230307C23Rik
RIKEN cDNA B230307C23 gene
chr5_+_90759299 0.153 ENSMUST00000031318.4
 Cxcl5
chemokine (C-X-C motif) ligand 5
chr4_+_114680769 0.152 ENSMUST00000146346.1
 Gm12829
predicted gene 12829
chr17_+_35424842 0.152 ENSMUST00000174699.1
 H2-Q6
histocompatibility 2, Q region locus 6
chr4_-_40239700 0.136 ENSMUST00000142055.1
 Ddx58
DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
chr16_+_32914094 0.130 ENSMUST00000023491.6
ENSMUST00000170899.1
ENSMUST00000171118.1
ENSMUST00000170201.1
ENSMUST00000165616.1
ENSMUST00000135193.2
 Lrch3





leucine-rich repeats and calponin homology (CH) domain containing 3





chr14_+_55560480 0.121 ENSMUST00000121622.1
ENSMUST00000143431.1
ENSMUST00000150481.1
 Dcaf11


DDB1 and CUL4 associated factor 11


chr7_+_16309577 0.118 ENSMUST00000002152.6
 Bbc3
BCL2 binding component 3
chr2_-_73485733 0.114 ENSMUST00000102680.1
 Wipf1
WAS/WASL interacting protein family, member 1
chr2_+_59612034 0.110 ENSMUST00000112568.1
ENSMUST00000037526.4
 Tanc1

tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1

chr12_-_76369586 0.095 ENSMUST00000176278.1
 Zbtb25
zinc finger and BTB domain containing 25
chr3_-_107760221 0.090 ENSMUST00000153114.1
ENSMUST00000118593.1
ENSMUST00000120243.1
 Csf1


colony stimulating factor 1 (macrophage)


chr7_+_43463145 0.087 ENSMUST00000107977.1
 Vsig10l
ZV-set and immunoglobulin domain containing 10 like
chr7_-_70360593 0.084 ENSMUST00000032768.7
 Nr2f2
nuclear receptor subfamily 2, group F, member 2
chr6_-_124741374 0.080 ENSMUST00000004389.5
 Grcc10
gene rich cluster, C10 gene
chr10_+_96616998 0.078 ENSMUST00000038377.7
 Btg1
B cell translocation gene 1, anti-proliferative
chr12_-_76369385 0.078 ENSMUST00000176187.1
ENSMUST00000167011.1
ENSMUST00000176967.1
 Zbtb25


zinc finger and BTB domain containing 25


chr14_+_80000292 0.073 ENSMUST00000088735.3
 Olfm4
olfactomedin 4
chr7_-_28766469 0.069 ENSMUST00000085851.5
ENSMUST00000032815.4
 Nfkbib

nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, beta

chr12_-_54862783 0.069 ENSMUST00000078124.7
 Cfl2
cofilin 2, muscle
chr4_-_117133953 0.066 ENSMUST00000076859.5
 Plk3
polo-like kinase 3
chr17_+_74717743 0.059 ENSMUST00000024882.6
 Ttc27
tetratricopeptide repeat domain 27
chr1_+_135133272 0.055 ENSMUST00000167080.1
 Ptpn7
protein tyrosine phosphatase, non-receptor type 7
chr17_+_35424870 0.051 ENSMUST00000113879.3
 H2-Q6
histocompatibility 2, Q region locus 6
chr11_-_84870646 0.046 ENSMUST00000018547.2
 Ggnbp2
gametogenetin binding protein 2
chr7_+_28766747 0.023 ENSMUST00000170068.1
ENSMUST00000072965.4
 Sirt2

sirtuin 2

chr12_+_111538101 0.006 ENSMUST00000166123.1
 Eif5
eukaryotic translation initiation factor 5
chr10_+_111125851 0.005 ENSMUST00000171120.1
 Gm5428
predicted gene 5428
chr5_-_122989086 0.002 ENSMUST00000046073.9
 Kdm2b
lysine (K)-specific demethylase 2B

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 2.6 GO:0001920 negative regulation of receptor recycling(GO:0001920)
0.3 1.8 GO:0071499 response to laminar fluid shear stress(GO:0034616) cellular response to laminar fluid shear stress(GO:0071499)
0.2 0.7 GO:0070942 neutrophil mediated cytotoxicity(GO:0070942) neutrophil mediated killing of symbiont cell(GO:0070943)
0.2 1.3 GO:0060842 arterial endothelial cell differentiation(GO:0060842)
0.1 0.6 GO:0009597 detection of virus(GO:0009597)
0.1 1.7 GO:0032688 negative regulation of interferon-beta production(GO:0032688)
0.1 0.8 GO:0007253 cytoplasmic sequestering of NF-kappaB(GO:0007253)
0.1 1.2 GO:0048484 enteric nervous system development(GO:0048484)
0.1 0.7 GO:0006490 oligosaccharide-lipid intermediate biosynthetic process(GO:0006490)
0.1 1.0 GO:0042994 cytoplasmic sequestering of transcription factor(GO:0042994)
0.0 0.3 GO:0034393 positive regulation of smooth muscle cell apoptotic process(GO:0034393) follicle-stimulating hormone signaling pathway(GO:0042699)
0.0 1.1 GO:0030212 hyaluronan metabolic process(GO:0030212)
0.0 0.6 GO:0032060 bleb assembly(GO:0032060)
0.0 0.2 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.0 0.1 GO:1904139 microglial cell migration(GO:1904124) regulation of microglial cell migration(GO:1904139)
0.0 0.1 GO:1900740 regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900739) positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900740)
0.0 0.9 GO:0010842 retina layer formation(GO:0010842)
0.0 0.7 GO:1900027 regulation of ruffle assembly(GO:1900027)
0.0 0.3 GO:0038063 collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063)
0.0 0.1 GO:2000271 positive regulation of fibroblast apoptotic process(GO:2000271)
0.0 0.4 GO:0048535 lymph node development(GO:0048535)
0.0 0.1 GO:0060838 lymphatic endothelial cell fate commitment(GO:0060838) regulation of transcription involved in lymphatic endothelial cell fate commitment(GO:0060849)
0.0 1.2 GO:0046847 filopodium assembly(GO:0046847)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 2.1 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.2 1.2 GO:0031315 extrinsic component of mitochondrial outer membrane(GO:0031315)
0.1 0.3 GO:0005587 collagen type IV trimer(GO:0005587) network-forming collagen trimer(GO:0098642) collagen network(GO:0098645) basement membrane collagen trimer(GO:0098651)
0.0 0.1 GO:1990682 CSF1-CSF1R complex(GO:1990682)
0.0 1.8 GO:0032587 ruffle membrane(GO:0032587)
0.0 0.3 GO:0031143 pseudopodium(GO:0031143)
0.0 0.2 GO:0042612 MHC class I protein complex(GO:0042612)
0.0 2.6 GO:0005802 trans-Golgi network(GO:0005802)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 2.6 GO:0001025 RNA polymerase III transcription factor binding(GO:0001025)
0.2 0.9 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.1 0.3 GO:0031896 V2 vasopressin receptor binding(GO:0031896)
0.1 0.7 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.1 0.2 GO:0004103 choline kinase activity(GO:0004103)
0.1 1.2 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 0.7 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.0 1.1 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 1.3 GO:0004896 cytokine receptor activity(GO:0004896)
0.0 0.0 GO:0042903 tubulin deacetylase activity(GO:0042903)
0.0 1.2 GO:0098811 transcriptional activator activity, RNA polymerase II transcription factor binding(GO:0001190) transcriptional repressor activity, RNA polymerase II activating transcription factor binding(GO:0098811)
0.0 0.2 GO:0030881 beta-2-microglobulin binding(GO:0030881)
0.0 0.7 GO:0042281 dolichyl pyrophosphate Man9GlcNAc2 alpha-1,3-glucosyltransferase activity(GO:0042281)