Motif ID: Rest

Z-value: 1.348


Transcription factors associated with Rest:

Gene SymbolEntrez IDGene Name
Rest ENSMUSG00000029249.9 Rest

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Restmm10_v2_chr5_+_77265454_77265549-0.401.6e-01Click!


Activity profile for motif Rest.

activity profile for motif Rest


Sorted Z-values histogram for motif Rest

Sorted Z-values for motif Rest



Network of associatons between targets according to the STRING database.



First level regulatory network of Rest

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Top targets:


Showing 1 to 20 of 78 entries
PromoterScoreRefseqGene SymbolGene Name
chr15_-_11037968 4.598 ENSMUST00000058007.5
 Rxfp3
relaxin family peptide receptor 3
chr2_-_180104463 3.991 ENSMUST00000056480.3
 Hrh3
histamine receptor H3
chr5_+_137030275 3.368 ENSMUST00000041543.8
 Vgf
VGF nerve growth factor inducible
chr19_+_42255704 3.134 ENSMUST00000087123.5
 Golga7b
golgi autoantigen, golgin subfamily a, 7B
chr7_+_122671401 2.594 ENSMUST00000182095.1
 Cacng3
calcium channel, voltage-dependent, gamma subunit 3
chr12_+_119945957 2.476 ENSMUST00000058644.8
 Tmem196
transmembrane protein 196
chr7_+_122671378 2.449 ENSMUST00000182563.1
 Cacng3
calcium channel, voltage-dependent, gamma subunit 3
chr13_-_56895737 2.092 ENSMUST00000022023.6
ENSMUST00000109871.1
 Trpc7

transient receptor potential cation channel, subfamily C, member 7

chr4_+_129136948 2.044 ENSMUST00000102600.3
 Fndc5
fibronectin type III domain containing 5
chr6_-_121473630 2.017 ENSMUST00000046373.5
 Iqsec3
IQ motif and Sec7 domain 3
chr7_+_51621830 1.775 ENSMUST00000032710.5
 Slc17a6
solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 6
chr17_-_83631892 1.432 ENSMUST00000051482.1
 Kcng3
potassium voltage-gated channel, subfamily G, member 3
chr4_-_153482768 1.393 ENSMUST00000105646.2
 Ajap1
adherens junction associated protein 1
chr2_-_27142429 1.343 ENSMUST00000151224.2
 Fam163b
family with sequence similarity 163, member B
chr4_-_129121234 1.334 ENSMUST00000030572.3
 Hpca
hippocalcin
chr4_+_130055010 1.329 ENSMUST00000123617.1
 Col16a1
collagen, type XVI, alpha 1
chr7_-_27396542 1.316 ENSMUST00000108363.1
 Sptbn4
spectrin beta, non-erythrocytic 4
chr12_-_84698769 1.315 ENSMUST00000095550.2
 Syndig1l
synapse differentiation inducing 1 like
chr9_+_40873981 1.309 ENSMUST00000067375.3
 Bsx
brain specific homeobox
chr12_+_113140198 1.302 ENSMUST00000084882.4
 Crip2
cysteine rich protein 2

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 36 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 5.0 GO:2000311 regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311)
0.3 4.6 GO:0051482 positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway(GO:0051482)
1.3 4.0 GO:0014063 negative regulation of serotonin secretion(GO:0014063)
0.3 3.4 GO:0043084 penile erection(GO:0043084)
0.8 2.3 GO:1900673 olefin metabolic process(GO:1900673)
0.1 2.1 GO:0006828 manganese ion transport(GO:0006828)
0.3 2.0 GO:0090336 positive regulation of brown fat cell differentiation(GO:0090336)
0.1 2.0 GO:0032011 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.1 1.8 GO:0001504 neurotransmitter uptake(GO:0001504)
0.4 1.3 GO:0030827 negative regulation of cGMP metabolic process(GO:0030824) negative regulation of cGMP biosynthetic process(GO:0030827) negative regulation of guanylate cyclase activity(GO:0031283)
0.2 1.3 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.1 1.3 GO:0060056 mammary gland involution(GO:0060056)
0.1 1.3 GO:0051894 integrin activation(GO:0033622) positive regulation of focal adhesion assembly(GO:0051894)
0.0 1.3 GO:0046676 negative regulation of insulin secretion(GO:0046676)
0.1 1.1 GO:0007614 short-term memory(GO:0007614)
0.0 1.1 GO:0051965 positive regulation of synapse assembly(GO:0051965)
0.3 1.0 GO:0006295 pyrimidine dimer repair by nucleotide-excision repair(GO:0000720) nucleotide-excision repair, DNA incision, 3'-to lesion(GO:0006295) nucleotide-excision repair, DNA incision, 5'-to lesion(GO:0006296) positive regulation of t-circle formation(GO:1904431)
0.3 0.9 GO:0070634 transepithelial ammonium transport(GO:0070634)
0.2 0.9 GO:1903237 negative regulation of leukocyte tethering or rolling(GO:1903237)
0.2 0.9 GO:0006538 glutamate catabolic process(GO:0006538)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 21 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 5.2 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.0 4.0 GO:0043209 myelin sheath(GO:0043209)
0.1 3.4 GO:0030667 secretory granule membrane(GO:0030667)
0.1 2.9 GO:0060077 inhibitory synapse(GO:0060077)
0.6 2.3 GO:0044307 dendritic branch(GO:0044307)
0.0 2.1 GO:0005801 cis-Golgi network(GO:0005801)
0.0 2.0 GO:0005777 peroxisome(GO:0005777) microbody(GO:0042579)
0.0 1.4 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.2 1.3 GO:0008091 spectrin(GO:0008091)
0.1 1.3 GO:0044327 dendritic spine head(GO:0044327)
0.0 1.3 GO:0005581 collagen trimer(GO:0005581)
0.3 1.0 GO:0000110 nucleotide-excision repair factor 1 complex(GO:0000110) ERCC4-ERCC1 complex(GO:0070522)
0.0 0.9 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.0 0.9 GO:0009925 basal plasma membrane(GO:0009925)
0.1 0.8 GO:0031428 box C/D snoRNP complex(GO:0031428)
0.0 0.8 GO:0048786 presynaptic active zone(GO:0048786)
0.1 0.5 GO:0031045 dense core granule(GO:0031045)
0.0 0.5 GO:1904115 axon cytoplasm(GO:1904115)
0.1 0.3 GO:0032426 stereocilium tip(GO:0032426)
0.1 0.2 GO:0044302 dentate gyrus mossy fiber(GO:0044302)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 24 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 5.0 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.1 4.6 GO:0008528 G-protein coupled peptide receptor activity(GO:0008528)
0.7 4.0 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.1 3.0 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.1 2.4 GO:0005179 hormone activity(GO:0005179)
0.2 2.3 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.1 2.2 GO:0030506 ankyrin binding(GO:0030506)
0.0 2.2 GO:0005496 steroid binding(GO:0005496)
0.2 2.1 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.1 2.0 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.1 1.8 GO:0005313 L-glutamate transmembrane transporter activity(GO:0005313)
0.1 1.4 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.1 1.0 GO:0001094 TFIID-class transcription factor binding(GO:0001094)
0.1 0.9 GO:0004351 glutamate decarboxylase activity(GO:0004351)
0.1 0.9 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.0 0.8 GO:0045296 cadherin binding(GO:0045296)
0.0 0.8 GO:0042054 histone methyltransferase activity(GO:0042054)
0.1 0.5 GO:0003976 UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity(GO:0003976)
0.0 0.5 GO:0001786 phosphatidylserine binding(GO:0001786)
0.0 0.5 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)