Motif ID: Rfx3_Rfx1_Rfx4

Z-value: 1.137

Transcription factors associated with Rfx3_Rfx1_Rfx4:

Gene SymbolEntrez IDGene Name
Rfx1 ENSMUSG00000031706.6 Rfx1
Rfx3 ENSMUSG00000040929.10 Rfx3
Rfx4 ENSMUSG00000020037.9 Rfx4

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Rfx4mm10_v2_chr10_+_84756055_84756084-0.479.1e-02Click!
Rfx3mm10_v2_chr19_-_28011138_280111810.332.4e-01Click!
Rfx1mm10_v2_chr8_+_84066824_84066882-0.195.1e-01Click!


Activity profile for motif Rfx3_Rfx1_Rfx4.

activity profile for motif Rfx3_Rfx1_Rfx4


Sorted Z-values histogram for motif Rfx3_Rfx1_Rfx4

Sorted Z-values for motif Rfx3_Rfx1_Rfx4



Network of associatons between targets according to the STRING database.



First level regulatory network of Rfx3_Rfx1_Rfx4

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr18_+_60925644 2.942 ENSMUST00000115297.1
 Camk2a
calcium/calmodulin-dependent protein kinase II alpha
chr18_+_60925612 2.080 ENSMUST00000102888.3
ENSMUST00000025519.4
 Camk2a

calcium/calmodulin-dependent protein kinase II alpha

chr5_+_24985840 1.545 ENSMUST00000075081.6
 1500035N22Rik
RIKEN cDNA 1500035N22 gene
chr12_-_84148449 1.424 ENSMUST00000061425.2
 Pnma1
paraneoplastic antigen MA1
chr19_-_57197435 1.423 ENSMUST00000111550.1
 Ablim1
actin-binding LIM protein 1
chr19_-_57197496 1.382 ENSMUST00000111544.1
 Ablim1
actin-binding LIM protein 1
chr19_-_57197377 1.372 ENSMUST00000111546.1
 Ablim1
actin-binding LIM protein 1
chr8_-_64733534 1.337 ENSMUST00000141021.1
 Sc4mol
sterol-C4-methyl oxidase-like
chr4_-_119415494 1.324 ENSMUST00000063642.2
 Ccdc30
coiled-coil domain containing 30
chr4_+_123183456 1.304 ENSMUST00000126995.1
 Hpcal4
hippocalcin-like 4
chr11_-_105944128 1.252 ENSMUST00000184086.1
 Cyb561
cytochrome b-561
chr2_+_121289589 1.187 ENSMUST00000094639.3
 Map1a
microtubule-associated protein 1 A
chr4_+_57434247 1.134 ENSMUST00000102905.1
 Palm2
paralemmin 2
chr1_+_66386968 1.131 ENSMUST00000145419.1
 Map2
microtubule-associated protein 2
chr15_+_98167806 1.119 ENSMUST00000031914.4
 AI836003
expressed sequence AI836003
chr7_+_99268338 1.088 ENSMUST00000107100.2
 Map6
microtubule-associated protein 6
chr8_+_123212857 1.075 ENSMUST00000060133.6
 Spata33
spermatogenesis associated 33
chr19_-_57197556 1.062 ENSMUST00000099294.2
 Ablim1
actin-binding LIM protein 1
chr9_-_121839460 1.053 ENSMUST00000135986.2
 Ccdc13
coiled-coil domain containing 13
chr7_+_131966446 1.049 ENSMUST00000045840.4
 Gpr26
G protein-coupled receptor 26

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 157 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.3 5.0 GO:0038166 angiotensin-activated signaling pathway(GO:0038166)
0.1 5.0 GO:0030032 lamellipodium assembly(GO:0030032)
0.0 2.5 GO:0022900 electron transport chain(GO:0022900)
0.0 1.9 GO:1903955 positive regulation of protein targeting to mitochondrion(GO:1903955)
0.0 1.7 GO:0031122 cytoplasmic microtubule organization(GO:0031122)
0.1 1.6 GO:0035721 intraciliary retrograde transport(GO:0035721)
0.0 1.4 GO:0042073 intraciliary transport(GO:0042073)
0.3 1.3 GO:0045343 MHC class I biosynthetic process(GO:0045341) regulation of MHC class I biosynthetic process(GO:0045343) positive regulation of MHC class I biosynthetic process(GO:0045345)
0.1 1.3 GO:2000821 AMPA glutamate receptor clustering(GO:0097113) glutamate receptor clustering(GO:0097688) regulation of grooming behavior(GO:2000821)
0.0 1.3 GO:0045494 photoreceptor cell maintenance(GO:0045494)
0.0 1.3 GO:0045454 cell redox homeostasis(GO:0045454)
0.1 1.2 GO:0036371 protein localization to M-band(GO:0036309) protein localization to T-tubule(GO:0036371)
0.0 1.2 GO:0002437 inflammatory response to antigenic stimulus(GO:0002437)
0.0 1.2 GO:0032418 lysosome localization(GO:0032418)
0.0 1.1 GO:0048268 clathrin coat assembly(GO:0048268)
0.2 1.0 GO:0090038 negative regulation of protein kinase C signaling(GO:0090038)
0.0 1.0 GO:0021954 central nervous system neuron development(GO:0021954)
0.0 0.9 GO:2000171 negative regulation of dendrite development(GO:2000171)
0.0 0.9 GO:0071480 cellular response to gamma radiation(GO:0071480)
0.0 0.8 GO:0006890 retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 74 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 6.2 GO:0032839 dendrite cytoplasm(GO:0032839)
0.1 5.5 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0 1.9 GO:0008180 COP9 signalosome(GO:0008180)
0.1 1.8 GO:0030992 intraciliary transport particle B(GO:0030992)
0.0 1.3 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.1 1.2 GO:0031430 M band(GO:0031430)
0.1 1.1 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
0.0 1.1 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 1.0 GO:0005801 cis-Golgi network(GO:0005801)
0.0 0.9 GO:0010369 chromocenter(GO:0010369)
0.0 0.8 GO:0001750 photoreceptor outer segment(GO:0001750)
0.1 0.7 GO:0030990 intraciliary transport particle(GO:0030990)
0.0 0.7 GO:0036038 MKS complex(GO:0036038)
0.0 0.7 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 0.7 GO:0030131 clathrin adaptor complex(GO:0030131)
0.0 0.7 GO:1990391 DNA repair complex(GO:1990391)
0.0 0.6 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 0.6 GO:0005640 nuclear outer membrane(GO:0005640)
0.0 0.6 GO:0016235 aggresome(GO:0016235)
0.0 0.6 GO:0000407 pre-autophagosomal structure(GO:0000407)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 111 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 5.3 GO:0003779 actin binding(GO:0003779)
0.2 4.4 GO:0032794 GTPase activating protein binding(GO:0032794)
0.8 2.3 GO:0022865 transmembrane electron transfer carrier(GO:0022865)
0.0 2.3 GO:0005246 calcium channel regulator activity(GO:0005246)
0.1 1.4 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.0 1.4 GO:0043014 alpha-tubulin binding(GO:0043014)
0.2 1.2 GO:0045505 dynein intermediate chain binding(GO:0045505)
0.2 1.2 GO:0032051 clathrin light chain binding(GO:0032051)
0.1 1.2 GO:0016864 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.0 1.2 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.0 1.2 GO:0035064 methylated histone binding(GO:0035064)
0.1 1.1 GO:0005519 cytoskeletal regulatory protein binding(GO:0005519)
0.1 1.0 GO:0031811 G-protein coupled nucleotide receptor binding(GO:0031811) P2Y1 nucleotide receptor binding(GO:0031812)
0.1 0.9 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.0 0.8 GO:0042171 lysophosphatidic acid acyltransferase activity(GO:0042171)
0.0 0.8 GO:0030276 clathrin binding(GO:0030276)
0.1 0.7 GO:0086080 connexin binding(GO:0071253) protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
0.0 0.7 GO:0070008 serine-type exopeptidase activity(GO:0070008)
0.0 0.7 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 0.7 GO:0097472 cyclin-dependent protein serine/threonine kinase activity(GO:0004693) cyclin-dependent protein kinase activity(GO:0097472)