Motif ID: Rfx5

Z-value: 0.477


Transcription factors associated with Rfx5:

Gene SymbolEntrez IDGene Name
Rfx5 ENSMUSG00000005774.6 Rfx5

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Rfx5mm10_v2_chr3_+_94954075_949542260.669.7e-03Click!


Activity profile for motif Rfx5.

activity profile for motif Rfx5


Sorted Z-values histogram for motif Rfx5

Sorted Z-values for motif Rfx5



Network of associatons between targets according to the STRING database.



First level regulatory network of Rfx5

PNG image of the network

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Top targets:


Showing 1 to 20 of 68 entries
PromoterScoreRefseqGene SymbolGene Name
chr17_+_34187545 0.656 ENSMUST00000170086.1
 Tap1
transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
chr17_+_34187789 0.642 ENSMUST00000041633.8
 Tap1
transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
chr11_+_117523526 0.496 ENSMUST00000132261.1
 Gm11734
predicted gene 11734
chr7_-_19692596 0.385 ENSMUST00000108451.2
ENSMUST00000045035.4
 Apoc1

apolipoprotein C-I

chr17_+_35861343 0.363 ENSMUST00000172931.1
 Nrm
nurim (nuclear envelope membrane protein)
chr10_-_19011948 0.361 ENSMUST00000105527.1
 Tnfaip3
tumor necrosis factor, alpha-induced protein 3
chr9_-_21291124 0.346 ENSMUST00000086374.6
 Cdkn2d
cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)
chr8_-_89187560 0.340 ENSMUST00000093326.2
 Gm5356
predicted pseudogene 5356
chr1_-_183147461 0.327 ENSMUST00000171366.1
 Disp1
dispatched homolog 1 (Drosophila)
chr14_+_55618023 0.320 ENSMUST00000002395.7
 Rec8
REC8 homolog (yeast)
chr17_+_34398802 0.309 ENSMUST00000114175.1
ENSMUST00000078615.5
ENSMUST00000139063.1
ENSMUST00000097348.2
 BC051142



cDNA sequence BC051142



chr8_-_85067982 0.286 ENSMUST00000177563.1
 Gm5741
predicted gene 5741
chr17_+_34263209 0.285 ENSMUST00000040828.5
 H2-Ab1
histocompatibility 2, class II antigen A, beta 1
chr17_+_35861318 0.269 ENSMUST00000074259.8
ENSMUST00000174873.1
 Nrm

nurim (nuclear envelope membrane protein)

chr15_+_36179299 0.261 ENSMUST00000047348.3
 Spag1
sperm associated antigen 1
chr7_-_45091713 0.255 ENSMUST00000141576.1
 Rcn3
reticulocalbin 3, EF-hand calcium binding domain
chr17_+_35379608 0.245 ENSMUST00000081435.4
 H2-Q4
histocompatibility 2, Q region locus 4
chrX_+_42526585 0.233 ENSMUST00000101619.3
 Gm10483
predicted gene 10483
chr19_+_37376359 0.228 ENSMUST00000012587.3
 Kif11
kinesin family member 11
chr11_+_61505138 0.202 ENSMUST00000102657.3
 B9d1
B9 protein domain 1

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 17 of 17 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.3 1.3 GO:0051708 intracellular transport of viral protein in host cell(GO:0019060) symbiont intracellular protein transport in host(GO:0030581) cytosol to ER transport(GO:0046967) intracellular protein transport in other organism involved in symbiotic interaction(GO:0051708)
0.1 0.4 GO:0070428 granuloma formation(GO:0002432) negative regulation of toll-like receptor 3 signaling pathway(GO:0034140) toll-like receptor 5 signaling pathway(GO:0034146) regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070428)
0.1 0.3 GO:0002339 B cell selection(GO:0002339)
0.0 0.3 GO:0048102 autophagic cell death(GO:0048102)
0.0 0.3 GO:0060539 diaphragm development(GO:0060539)
0.0 0.3 GO:0007141 male meiosis I(GO:0007141)
0.0 0.3 GO:0002474 antigen processing and presentation of peptide antigen via MHC class I(GO:0002474)
0.1 0.2 GO:0002636 positive regulation of germinal center formation(GO:0002636)
0.0 0.2 GO:0046602 regulation of mitotic centrosome separation(GO:0046602)
0.0 0.2 GO:0002481 antigen processing and presentation of exogenous peptide antigen via MHC class Ib(GO:0002477) antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent(GO:0002481)
0.0 0.2 GO:0031665 negative regulation of lipopolysaccharide-mediated signaling pathway(GO:0031665)
0.0 0.2 GO:0019886 antigen processing and presentation of exogenous peptide antigen via MHC class II(GO:0019886)
0.0 0.1 GO:2000832 protein-chromophore linkage(GO:0018298) negative regulation of steroid hormone secretion(GO:2000832) negative regulation of corticosteroid hormone secretion(GO:2000847) negative regulation of glucocorticoid secretion(GO:2000850)
0.0 0.1 GO:0090071 negative regulation of ribosome biogenesis(GO:0090071)
0.0 0.1 GO:0006013 mannose metabolic process(GO:0006013)
0.0 0.1 GO:0089711 L-glutamate transmembrane transport(GO:0089711)
0.0 0.1 GO:0021785 branchiomotor neuron axon guidance(GO:0021785)

Gene overrepresentation in cellular_component category:

Showing 1 to 8 of 8 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 1.3 GO:0042825 TAP complex(GO:0042825)
0.1 0.7 GO:0042613 MHC class II protein complex(GO:0042613)
0.0 0.6 GO:0005652 nuclear lamina(GO:0005652)
0.0 0.5 GO:0042611 MHC protein complex(GO:0042611)
0.0 0.4 GO:0034361 very-low-density lipoprotein particle(GO:0034361) triglyceride-rich lipoprotein particle(GO:0034385)
0.1 0.3 GO:0000798 nuclear cohesin complex(GO:0000798) nuclear meiotic cohesin complex(GO:0034991)
0.0 0.2 GO:0036038 MKS complex(GO:0036038)
0.0 0.1 GO:0002116 semaphorin receptor complex(GO:0002116)

Gene overrepresentation in molecular_function category:

Showing 1 to 10 of 10 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.3 1.3 GO:0023029 peptide antigen-transporting ATPase activity(GO:0015433) MHC class Ib protein binding(GO:0023029) tapasin binding(GO:0046980)
0.0 0.7 GO:0042605 peptide antigen binding(GO:0042605)
0.0 0.4 GO:0023026 MHC protein complex binding(GO:0023023) MHC class II protein complex binding(GO:0023026)
0.0 0.4 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.0 0.3 GO:0015197 peptide transporter activity(GO:0015197)
0.0 0.3 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.1 0.2 GO:0008158 hedgehog receptor activity(GO:0008158)
0.0 0.2 GO:0004128 cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
0.0 0.2 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
0.0 0.1 GO:0009881 photoreceptor activity(GO:0009881)