Motif ID: Rhox11

Z-value: 0.632


Transcription factors associated with Rhox11:

Gene SymbolEntrez IDGene Name
Rhox11 ENSMUSG00000051038.9 Rhox11



Activity profile for motif Rhox11.

activity profile for motif Rhox11


Sorted Z-values histogram for motif Rhox11

Sorted Z-values for motif Rhox11



Network of associatons between targets according to the STRING database.



First level regulatory network of Rhox11

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr2_-_57113053 0.980 ENSMUST00000112627.1
 Nr4a2
nuclear receptor subfamily 4, group A, member 2
chr1_+_99772765 0.938 ENSMUST00000086738.3
 Cntnap5b
contactin associated protein-like 5B
chr13_-_23562369 0.891 ENSMUST00000105107.1
 Hist1h3e
histone cluster 1, H3e
chr14_-_20496780 0.858 ENSMUST00000022353.3
 Mss51
MSS51 mitochondrial translational activator
chr4_+_126556935 0.740 ENSMUST00000048391.8
 Clspn
claspin
chr9_-_16378231 0.694 ENSMUST00000082170.5
 Fat3
FAT tumor suppressor homolog 3 (Drosophila)
chr5_+_98329298 0.665 ENSMUST00000080333.3
 1700007G11Rik
RIKEN cDNA 1700007G11 gene
chr8_+_104831572 0.556 ENSMUST00000059449.6
 Ces2b
carboxyesterase 2B
chr6_-_34977999 0.538 ENSMUST00000044387.7
 2010107G12Rik
RIKEN cDNA 2010107G12 gene
chr2_-_150362708 0.525 ENSMUST00000051153.5
 3300002I08Rik
RIKEN cDNA 3300002I08 gene
chr9_-_107289847 0.495 ENSMUST00000035194.2
 Mapkapk3
mitogen-activated protein kinase-activated protein kinase 3
chr11_+_29373618 0.489 ENSMUST00000040182.6
ENSMUST00000109477.1
 Ccdc88a

coiled coil domain containing 88A

chr15_+_7129557 0.487 ENSMUST00000067190.5
ENSMUST00000164529.1
 Lifr

leukemia inhibitory factor receptor

chr18_-_24709348 0.442 ENSMUST00000067987.1
 Gm9955
predicted gene 9955
chr9_+_86743616 0.405 ENSMUST00000036426.6
 Prss35
protease, serine, 35
chr15_+_41789495 0.403 ENSMUST00000090095.5
ENSMUST00000022918.7
 Oxr1

oxidation resistance 1

chr7_-_44892358 0.401 ENSMUST00000003049.6
 Med25
mediator of RNA polymerase II transcription, subunit 25 homolog (yeast)
chr5_+_110135823 0.394 ENSMUST00000112519.2
ENSMUST00000014812.8
 Chfr

checkpoint with forkhead and ring finger domains

chr9_+_86743641 0.381 ENSMUST00000179574.1
 Prss35
protease, serine, 35
chr3_+_127791374 0.378 ENSMUST00000171621.1
 Tifa
TRAF-interacting protein with forkhead-associated domain
chr3_-_121171678 0.374 ENSMUST00000170781.1
ENSMUST00000039761.5
ENSMUST00000106467.1
ENSMUST00000106466.3
ENSMUST00000164925.2
 Rwdd3




RWD domain containing 3




chr1_+_24177610 0.372 ENSMUST00000054588.8
 Col9a1
collagen, type IX, alpha 1
chr8_-_105827190 0.360 ENSMUST00000041400.5
 Ranbp10
RAN binding protein 10
chr5_+_121220191 0.350 ENSMUST00000119892.2
ENSMUST00000042614.6
 Gm15800

predicted gene 15800

chr11_-_102082464 0.347 ENSMUST00000100398.4
 Mpp2
membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2)
chr9_-_44713196 0.344 ENSMUST00000144251.1
ENSMUST00000156918.1
 Phldb1

pleckstrin homology-like domain, family B, member 1

chr4_+_126556994 0.340 ENSMUST00000147675.1
 Clspn
claspin
chr15_+_36179299 0.334 ENSMUST00000047348.3
 Spag1
sperm associated antigen 1
chr6_+_135065651 0.334 ENSMUST00000050104.7
 Gprc5a
G protein-coupled receptor, family C, group 5, member A
chr15_+_8169067 0.331 ENSMUST00000110617.1
 2410089E03Rik
RIKEN cDNA 2410089E03 gene
chr11_+_70639118 0.315 ENSMUST00000055184.6
ENSMUST00000108551.2
 Gp1ba

glycoprotein 1b, alpha polypeptide

chr5_+_111733924 0.306 ENSMUST00000180627.1
 Gm26897
predicted gene, 26897
chr8_+_3353415 0.296 ENSMUST00000098966.3
 A430078G23Rik
RIKEN cDNA A430078G23 gene
chr10_-_127311740 0.274 ENSMUST00000037290.5
ENSMUST00000171564.1
 Mars

methionine-tRNA synthetase

chr5_+_21186267 0.273 ENSMUST00000036031.8
 Gsap
gamma-secretase activating protein
chr5_+_143933059 0.263 ENSMUST00000166847.1
 Rsph10b
radial spoke head 10 homolog B (Chlamydomonas)
chr16_+_29579331 0.238 ENSMUST00000160597.1
 Opa1
optic atrophy 1
chr5_+_138187485 0.235 ENSMUST00000110934.2
 Cnpy4
canopy 4 homolog (zebrafish)
chr9_+_50768228 0.234 ENSMUST00000042391.6
 Fdxacb1
ferredoxin-fold anticodon binding domain containing 1
chr16_+_29579347 0.229 ENSMUST00000038867.6
ENSMUST00000161186.1
 Opa1

optic atrophy 1

chr2_+_178118975 0.228 ENSMUST00000108917.1
 Phactr3
phosphatase and actin regulator 3
chrX_-_111536325 0.220 ENSMUST00000156639.1
 Rps6ka6
ribosomal protein S6 kinase polypeptide 6
chr5_+_93093428 0.215 ENSMUST00000074733.7
 Sept11
septin 11
chr2_-_5862923 0.215 ENSMUST00000071016.2
 Gm13199
predicted gene 13199
chr17_+_79614900 0.207 ENSMUST00000040368.2
 Rmdn2
regulator of microtubule dynamics 2
chr13_-_3611064 0.206 ENSMUST00000096069.3
 BC016423
cDNA sequence BC016423
chr5_-_114858682 0.183 ENSMUST00000066959.4
 Gm9936
predicted gene 9936
chr11_-_97700327 0.179 ENSMUST00000018681.7
 Pcgf2
polycomb group ring finger 2
chr8_+_72492915 0.177 ENSMUST00000181452.1
 Gm17435
predicted gene, 17435
chr7_-_46795881 0.156 ENSMUST00000107653.1
ENSMUST00000107654.1
ENSMUST00000014562.7
ENSMUST00000152759.1
 Hps5



Hermansky-Pudlak syndrome 5 homolog (human)



chr2_-_131352857 0.148 ENSMUST00000059372.4
 Rnf24
ring finger protein 24
chr9_-_8134294 0.123 ENSMUST00000037397.6
 AK129341
cDNA sequence AK129341
chr8_-_81014866 0.121 ENSMUST00000042724.6
 Usp38
ubiquitin specific peptidase 38
chr11_-_102880981 0.120 ENSMUST00000107060.1
 Eftud2
elongation factor Tu GTP binding domain containing 2
chr12_+_76837408 0.112 ENSMUST00000041008.9
 Fntb
farnesyltransferase, CAAX box, beta
chr19_-_60581013 0.110 ENSMUST00000111460.3
ENSMUST00000081790.7
ENSMUST00000166712.1
 Cacul1


CDK2 associated, cullin domain 1


chr17_-_47016956 0.108 ENSMUST00000165525.1
 Gm16494
predicted gene 16494
chr4_-_119383732 0.102 ENSMUST00000044781.2
ENSMUST00000084307.3
 Ccdc30

coiled-coil domain containing 30

chr8_+_94386438 0.100 ENSMUST00000161576.1
 Herpud1
homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
chr11_-_102880925 0.096 ENSMUST00000021306.7
 Eftud2
elongation factor Tu GTP binding domain containing 2
chr9_-_20521375 0.093 ENSMUST00000068296.7
ENSMUST00000174462.1
 Zfp266

zinc finger protein 266

chr3_+_156561792 0.091 ENSMUST00000074015.4
 Negr1
neuronal growth regulator 1
chr4_-_137048695 0.091 ENSMUST00000049583.7
 Zbtb40
zinc finger and BTB domain containing 40
chr6_-_106800051 0.085 ENSMUST00000013882.7
ENSMUST00000049675.4
ENSMUST00000113239.3
 Crbn


cereblon


chrX_-_102157065 0.083 ENSMUST00000056904.2
 Ercc6l
excision repair cross-complementing rodent repair deficiency complementation group 6 like
chr6_+_128662379 0.080 ENSMUST00000032518.4
 Clec2h
C-type lectin domain family 2, member h
chr8_+_94386486 0.078 ENSMUST00000034220.7
 Herpud1
homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
chr3_+_90603767 0.063 ENSMUST00000001046.5
ENSMUST00000107330.1
 S100a4

S100 calcium binding protein A4

chr9_-_50768109 0.055 ENSMUST00000177546.1
ENSMUST00000176238.1
 1110032A03Rik

RIKEN cDNA 1110032A03 gene

chr9_+_20644851 0.053 ENSMUST00000161882.1
 Ubl5
ubiquitin-like 5
chr4_+_86575668 0.041 ENSMUST00000091064.6
 Rraga
Ras-related GTP binding A
chr7_+_46796088 0.038 ENSMUST00000006774.4
ENSMUST00000165031.1
 Gtf2h1

general transcription factor II H, polypeptide 1

chr11_+_98446826 0.036 ENSMUST00000019456.4
 Grb7
growth factor receptor bound protein 7
chr10_+_21295979 0.035 ENSMUST00000020153.8
ENSMUST00000092674.6
 Hbs1l

Hbs1-like (S. cerevisiae)

chr19_-_8818924 0.030 ENSMUST00000153281.1
 Ttc9c
tetratricopeptide repeat domain 9C
chr18_+_62977854 0.028 ENSMUST00000150267.1
 Napg
N-ethylmaleimide sensitive fusion protein attachment protein gamma
chr6_+_54264839 0.028 ENSMUST00000146114.1
 Chn2
chimerin (chimaerin) 2
chr9_+_20644792 0.026 ENSMUST00000162303.1
ENSMUST00000161486.1
 Ubl5

ubiquitin-like 5

chr7_-_28008416 0.023 ENSMUST00000180024.1
 Zfp850
zinc finger protein 850
chr5_+_37735519 0.021 ENSMUST00000073554.3
 Cytl1
cytokine-like 1
chr18_-_60501983 0.018 ENSMUST00000042710.6
 Smim3
small integral membrane protein 3
chr18_+_6765171 0.013 ENSMUST00000097680.5
 Rab18
RAB18, member RAS oncogene family
chr3_+_68468162 0.001 ENSMUST00000182532.1
 Schip1
schwannomin interacting protein 1

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.0 GO:0051866 general adaptation syndrome(GO:0051866)
0.2 0.5 GO:0038165 oncostatin-M-mediated signaling pathway(GO:0038165)
0.2 0.5 GO:0010636 positive regulation of mitochondrial fusion(GO:0010636)
0.1 1.1 GO:0033314 mitotic DNA replication checkpoint(GO:0033314)
0.1 0.4 GO:1902071 positive regulation of cellular response to hypoxia(GO:1900039) regulation of hypoxia-inducible factor-1alpha signaling pathway(GO:1902071)
0.1 0.5 GO:0044351 macropinocytosis(GO:0044351)
0.1 0.2 GO:0006432 phenylalanyl-tRNA aminoacylation(GO:0006432)
0.1 0.3 GO:1904491 protein localization to ciliary transition zone(GO:1904491)
0.0 0.3 GO:0042730 fibrinolysis(GO:0042730)
0.0 0.3 GO:2001197 regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904259) positive regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904261) basement membrane assembly involved in embryonic body morphogenesis(GO:2001197)
0.0 0.2 GO:1903071 positive regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903071)
0.0 0.4 GO:0071447 cellular response to hydroperoxide(GO:0071447)
0.0 0.9 GO:0034723 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.0 0.1 GO:0018343 protein farnesylation(GO:0018343)
0.0 0.3 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.0 0.4 GO:0035563 positive regulation of chromatin binding(GO:0035563)
0.0 0.7 GO:0010842 retina layer formation(GO:0010842)
0.0 0.4 GO:0003417 growth plate cartilage development(GO:0003417)
0.0 0.2 GO:2000381 negative regulation of mesoderm development(GO:2000381)
0.0 0.3 GO:1902993 positive regulation of beta-amyloid formation(GO:1902004) positive regulation of amyloid precursor protein catabolic process(GO:1902993)
0.0 0.1 GO:0032463 negative regulation of protein homooligomerization(GO:0032463)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0005594 collagen type IX trimer(GO:0005594)
0.1 0.5 GO:0031314 extrinsic component of mitochondrial inner membrane(GO:0031314)
0.1 0.2 GO:1990037 Lewy body core(GO:1990037)
0.0 0.1 GO:0005965 protein farnesyltransferase complex(GO:0005965)
0.0 0.3 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.0 0.9 GO:0000788 nuclear nucleosome(GO:0000788)
0.0 0.3 GO:0045180 basal cortex(GO:0045180)
0.0 0.2 GO:0001739 sex chromatin(GO:0001739)
0.0 0.0 GO:1990130 Iml1 complex(GO:1990130)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.1 GO:0010997 anaphase-promoting complex binding(GO:0010997)
0.2 0.5 GO:0004923 leukemia inhibitory factor receptor activity(GO:0004923) oncostatin-M receptor activity(GO:0004924)
0.1 0.4 GO:0005087 Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.0 0.2 GO:0004826 phenylalanine-tRNA ligase activity(GO:0004826)
0.0 0.1 GO:0004660 protein farnesyltransferase activity(GO:0004660)
0.0 1.0 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 0.6 GO:0050253 prenylcysteine methylesterase activity(GO:0010296) 1-oxa-2-oxocycloheptane lactonase activity(GO:0018731) sulfolactone hydrolase activity(GO:0018732) butyrolactone hydrolase activity(GO:0018734) endosulfan lactone lactonase activity(GO:0034892) L-ascorbate 6-phosphate lactonase activity(GO:0035460) Ser-tRNA(Thr) hydrolase activity(GO:0043905) Ala-tRNA(Pro) hydrolase activity(GO:0043906) Cys-tRNA(Pro) hydrolase activity(GO:0043907) Ser(Gly)-tRNA(Ala) hydrolase activity(GO:0043908) all-trans-retinyl-palmitate hydrolase, all-trans-retinol forming activity(GO:0047376) retinyl-palmitate esterase activity(GO:0050253) mannosyl-oligosaccharide 1,6-alpha-mannosidase activity(GO:0052767) mannosyl-oligosaccharide 1,3-alpha-mannosidase activity(GO:0052768) methyl indole-3-acetate esterase activity(GO:0080030) methyl salicylate esterase activity(GO:0080031) methyl jasmonate esterase activity(GO:0080032)
0.0 0.5 GO:0043422 protein kinase B binding(GO:0043422)
0.0 0.5 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931) calcium-dependent protein kinase activity(GO:0010857)
0.0 0.2 GO:0097027 ubiquitin-protein transferase activator activity(GO:0097027)
0.0 0.4 GO:0046965 retinoid X receptor binding(GO:0046965)
0.0 0.2 GO:0008599 protein phosphatase type 1 regulator activity(GO:0008599)
0.0 0.1 GO:0050786 RAGE receptor binding(GO:0050786)
0.0 0.8 GO:0004252 serine-type endopeptidase activity(GO:0004252)