Motif ID: Rhox4e_Rhox6_Vax2

Z-value: 0.896

Transcription factors associated with Rhox4e_Rhox6_Vax2:

Gene SymbolEntrez IDGene Name
Rhox4e ENSMUSG00000071770.4 Rhox4e
Rhox6 ENSMUSG00000006200.3 Rhox6
Vax2 ENSMUSG00000034777.1 Vax2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Vax2mm10_v2_chr6_+_83711232_83711288-0.039.2e-01Click!


Activity profile for motif Rhox4e_Rhox6_Vax2.

activity profile for motif Rhox4e_Rhox6_Vax2


Sorted Z-values histogram for motif Rhox4e_Rhox6_Vax2

Sorted Z-values for motif Rhox4e_Rhox6_Vax2



Network of associatons between targets according to the STRING database.



First level regulatory network of Rhox4e_Rhox6_Vax2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Top targets:


Showing 1 to 20 of 182 entries
PromoterScoreRefseqGene SymbolGene Name
chr15_-_67113909 9.349 ENSMUST00000092640.5
 St3gal1
ST3 beta-galactoside alpha-2,3-sialyltransferase 1
chr13_-_102906046 2.225 ENSMUST00000171791.1
 Mast4
microtubule associated serine/threonine kinase family member 4
chr5_-_84417359 2.060 ENSMUST00000113401.1
 Epha5
Eph receptor A5
chr1_+_72284367 2.042 ENSMUST00000027380.5
ENSMUST00000141783.1
 Tmem169

transmembrane protein 169

chr13_-_102905740 1.885 ENSMUST00000167462.1
 Mast4
microtubule associated serine/threonine kinase family member 4
chr5_+_37185897 1.808 ENSMUST00000094840.3
 Gm1043
predicted gene 1043
chr9_-_75597643 1.560 ENSMUST00000164100.1
 Tmod2
tropomodulin 2
chr2_+_69897255 1.492 ENSMUST00000131553.1
 Ubr3
ubiquitin protein ligase E3 component n-recognin 3
chr15_-_60824942 1.409 ENSMUST00000100635.3
 Fam84b
family with sequence similarity 84, member B
chr10_-_33951190 1.288 ENSMUST00000048222.4
 Zufsp
zinc finger with UFM1-specific peptidase domain
chrX_-_60893430 1.253 ENSMUST00000135107.2
 Sox3
SRY-box containing gene 3
chr2_+_65845833 1.251 ENSMUST00000053910.3
 Csrnp3
cysteine-serine-rich nuclear protein 3
chr4_-_14621669 1.212 ENSMUST00000143105.1
 Slc26a7
solute carrier family 26, member 7
chr1_-_172027269 1.153 ENSMUST00000027837.6
ENSMUST00000111264.1
 Vangl2

vang-like 2 (van gogh, Drosophila)

chr3_+_121953213 1.139 ENSMUST00000037958.7
ENSMUST00000128366.1
 Arhgap29

Rho GTPase activating protein 29

chr7_-_25005895 1.109 ENSMUST00000102858.3
ENSMUST00000080882.6
 Atp1a3

ATPase, Na+/K+ transporting, alpha 3 polypeptide

chr4_-_14621494 1.063 ENSMUST00000149633.1
 Slc26a7
solute carrier family 26, member 7
chr14_+_5517172 0.996 ENSMUST00000178220.1
 Gm3488
predicted gene, 3488
chr14_+_5164535 0.996 ENSMUST00000179659.1
 Gm3317
predicted gene 3317
chr2_-_150255591 0.995 ENSMUST00000063463.5
 Gm21994
predicted gene 21994

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 56 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.5 9.3 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.0 4.5 GO:0018105 peptidyl-serine phosphorylation(GO:0018105)
0.4 2.5 GO:0019532 oxalate transport(GO:0019532)
0.1 2.2 GO:0003301 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.2 2.1 GO:0071372 cellular response to follicle-stimulating hormone stimulus(GO:0071372)
0.5 2.0 GO:0071596 ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596)
0.0 2.0 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.6 1.7 GO:0060478 acrosomal vesicle exocytosis(GO:0060478)
0.3 1.6 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.1 1.3 GO:0007530 sex determination(GO:0007530)
0.4 1.2 GO:0060489 establishment of body hair or bristle planar orientation(GO:0048104) establishment of body hair planar orientation(GO:0048105) orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060488) planar dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060489) lateral sprouting involved in lung morphogenesis(GO:0060490)
0.1 1.2 GO:0021860 pyramidal neuron development(GO:0021860)
0.1 1.1 GO:0036376 sodium ion export from cell(GO:0036376)
0.0 0.9 GO:0016574 histone ubiquitination(GO:0016574)
0.1 0.8 GO:0000467 exonucleolytic trimming involved in rRNA processing(GO:0000459) exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000467)
0.1 0.8 GO:0016198 axon choice point recognition(GO:0016198)
0.2 0.6 GO:0048818 embryonic nail plate morphogenesis(GO:0035880) positive regulation of hair follicle maturation(GO:0048818) positive regulation of catagen(GO:0051795) frontal suture morphogenesis(GO:0060364)
0.1 0.6 GO:0008627 intrinsic apoptotic signaling pathway in response to osmotic stress(GO:0008627)
0.1 0.6 GO:0070562 regulation of vitamin D receptor signaling pathway(GO:0070562)
0.0 0.6 GO:0046069 cGMP catabolic process(GO:0046069)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 27 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 9.2 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 2.1 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.1 2.0 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.1 1.6 GO:0005865 striated muscle thin filament(GO:0005865)
0.3 1.2 GO:0060187 cell pole(GO:0060187)
0.2 1.1 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890) dendritic spine neck(GO:0044326)
0.1 1.1 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
0.1 0.9 GO:0033503 HULC complex(GO:0033503)
0.1 0.8 GO:0071204 histone pre-mRNA 3'end processing complex(GO:0071204)
0.1 0.8 GO:0031527 filopodium membrane(GO:0031527)
0.1 0.6 GO:0005726 perichromatin fibrils(GO:0005726)
0.0 0.6 GO:0034706 voltage-gated sodium channel complex(GO:0001518) sodium channel complex(GO:0034706)
0.0 0.6 GO:1990391 DNA repair complex(GO:1990391)
0.1 0.5 GO:0031315 extrinsic component of mitochondrial outer membrane(GO:0031315)
0.0 0.5 GO:0031258 lamellipodium membrane(GO:0031258)
0.1 0.4 GO:0045254 pyruvate dehydrogenase complex(GO:0045254)
0.0 0.4 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.0 0.4 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.0 0.4 GO:0016235 aggresome(GO:0016235)
0.0 0.3 GO:0005640 nuclear outer membrane(GO:0005640)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 39 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.2 9.3 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.0 4.1 GO:0000287 magnesium ion binding(GO:0000287)
0.2 2.5 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.3 2.1 GO:0005004 GPI-linked ephrin receptor activity(GO:0005004)
0.2 1.6 GO:0005523 tropomyosin binding(GO:0005523)
0.0 1.6 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.0 1.2 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.1 1.1 GO:0103116 alpha-D-galactofuranose transporter activity(GO:0103116)
0.0 0.9 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.3 0.8 GO:0071207 histone pre-mRNA stem-loop binding(GO:0071207)
0.1 0.8 GO:0035727 lysophosphatidic acid binding(GO:0035727)
0.0 0.8 GO:0017161 phosphohistidine phosphatase activity(GO:0008969) inositol-1,3,4-trisphosphate 4-phosphatase activity(GO:0017161) NADP phosphatase activity(GO:0019178) 5-amino-6-(5-phosphoribitylamino)uracil phosphatase activity(GO:0043726) phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity(GO:0043813) inositol-1,3,4,5,6-pentakisphosphate 1-phosphatase activity(GO:0052825) inositol-3,4-bisphosphate 4-phosphatase activity(GO:0052828) inositol-1,3,4-trisphosphate 1-phosphatase activity(GO:0052829) inositol-1,3,4,6-tetrakisphosphate 6-phosphatase activity(GO:0052830) inositol-1,3,4,6-tetrakisphosphate 1-phosphatase activity(GO:0052831) phosphatidylinositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052867) IDP phosphatase activity(GO:1990003)
0.1 0.6 GO:0034056 estrogen response element binding(GO:0034056)
0.0 0.6 GO:0043522 leucine zipper domain binding(GO:0043522)
0.0 0.6 GO:0030553 cGMP binding(GO:0030553)
0.0 0.6 GO:0042162 telomeric DNA binding(GO:0042162)
0.1 0.5 GO:0033814 propanoyl-CoA C-acyltransferase activity(GO:0033814) propionyl-CoA C2-trimethyltridecanoyltransferase activity(GO:0050632) phosphatidylethanolamine transporter activity(GO:1904121)
0.1 0.5 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.0 0.5 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.1 0.4 GO:0030292 protein tyrosine kinase inhibitor activity(GO:0030292)