Motif ID: Rhox4e_Rhox6_Vax2
Z-value: 0.896
Transcription factors associated with Rhox4e_Rhox6_Vax2:
Gene Symbol | Entrez ID | Gene Name |
---|---|---|
Rhox4e | ENSMUSG00000071770.4 | Rhox4e |
Rhox6 | ENSMUSG00000006200.3 | Rhox6 |
Vax2 | ENSMUSG00000034777.1 | Vax2 |
Activity-expression correlation:
Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
---|---|---|---|---|
Vax2 | mm10_v2_chr6_+_83711232_83711288 | -0.03 | 9.2e-01 | Click! |
Top targets:
Gene overrepresentation in biological_process category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.6 | 1.7 | GO:0060478 | acrosomal vesicle exocytosis(GO:0060478) |
0.5 | 2.0 | GO:0071596 | ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596) |
0.5 | 9.3 | GO:0001574 | ganglioside biosynthetic process(GO:0001574) |
0.4 | 1.2 | GO:0060489 | establishment of body hair or bristle planar orientation(GO:0048104) establishment of body hair planar orientation(GO:0048105) orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060488) planar dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060489) lateral sprouting involved in lung morphogenesis(GO:0060490) |
0.4 | 2.5 | GO:0019532 | oxalate transport(GO:0019532) |
0.3 | 1.6 | GO:0051694 | pointed-end actin filament capping(GO:0051694) |
0.2 | 2.1 | GO:0071372 | cellular response to follicle-stimulating hormone stimulus(GO:0071372) |
0.2 | 0.6 | GO:0048818 | embryonic nail plate morphogenesis(GO:0035880) positive regulation of hair follicle maturation(GO:0048818) positive regulation of catagen(GO:0051795) frontal suture morphogenesis(GO:0060364) |
0.2 | 0.5 | GO:0019085 | early viral transcription(GO:0019085) |
0.1 | 0.6 | GO:0008627 | intrinsic apoptotic signaling pathway in response to osmotic stress(GO:0008627) |
0.1 | 0.4 | GO:2000393 | negative regulation of lamellipodium morphogenesis(GO:2000393) |
0.1 | 0.5 | GO:0032382 | positive regulation of intracellular lipid transport(GO:0032379) positive regulation of intracellular sterol transport(GO:0032382) positive regulation of intracellular cholesterol transport(GO:0032385) lipid hydroperoxide transport(GO:1901373) positive regulation of cholesterol import(GO:1904109) positive regulation of sterol import(GO:2000911) |
0.1 | 0.4 | GO:0016056 | rhodopsin mediated signaling pathway(GO:0016056) |
0.1 | 0.5 | GO:0061738 | late endosomal microautophagy(GO:0061738) |
0.1 | 0.8 | GO:0000467 | exonucleolytic trimming involved in rRNA processing(GO:0000459) exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000467) |
0.1 | 0.6 | GO:0070562 | regulation of vitamin D receptor signaling pathway(GO:0070562) |
0.1 | 1.1 | GO:0036376 | sodium ion export from cell(GO:0036376) |
0.1 | 0.8 | GO:0016198 | axon choice point recognition(GO:0016198) |
0.1 | 0.3 | GO:0032512 | regulation of protein phosphatase type 2B activity(GO:0032512) positive regulation of ryanodine-sensitive calcium-release channel activity(GO:0060316) |
0.1 | 1.2 | GO:0021860 | pyramidal neuron development(GO:0021860) |
0.1 | 0.2 | GO:0042420 | dopamine catabolic process(GO:0042420) |
0.1 | 1.3 | GO:0007530 | sex determination(GO:0007530) |
0.1 | 2.2 | GO:0003301 | physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049) |
0.1 | 0.3 | GO:0038032 | termination of G-protein coupled receptor signaling pathway(GO:0038032) |
0.1 | 0.4 | GO:0061732 | mitochondrial acetyl-CoA biosynthetic process from pyruvate(GO:0061732) |
0.0 | 0.2 | GO:0043490 | malate-aspartate shuttle(GO:0043490) |
0.0 | 0.4 | GO:0006265 | DNA topological change(GO:0006265) |
0.0 | 0.5 | GO:0071578 | zinc II ion transmembrane import(GO:0071578) |
0.0 | 0.2 | GO:0051013 | microtubule severing(GO:0051013) |
0.0 | 0.1 | GO:0048294 | negative regulation of isotype switching to IgE isotypes(GO:0048294) |
0.0 | 0.5 | GO:0006107 | oxaloacetate metabolic process(GO:0006107) |
0.0 | 0.6 | GO:0046069 | cGMP catabolic process(GO:0046069) |
0.0 | 0.2 | GO:0060903 | positive regulation of meiosis I(GO:0060903) |
0.0 | 0.2 | GO:1901837 | negative regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901837) |
0.0 | 0.3 | GO:0031937 | positive regulation of chromatin silencing(GO:0031937) |
0.0 | 0.2 | GO:0015791 | polyol transport(GO:0015791) urea transport(GO:0015840) bile acid secretion(GO:0032782) urea transmembrane transport(GO:0071918) |
0.0 | 0.3 | GO:0001675 | acrosome assembly(GO:0001675) |
0.0 | 0.2 | GO:1903377 | negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903377) |
0.0 | 2.0 | GO:0010923 | negative regulation of phosphatase activity(GO:0010923) |
0.0 | 0.1 | GO:0018158 | protein oxidation(GO:0018158) |
0.0 | 0.1 | GO:0035553 | oxidative RNA demethylation(GO:0035513) oxidative single-stranded RNA demethylation(GO:0035553) |
0.0 | 0.1 | GO:0031119 | tRNA pseudouridine synthesis(GO:0031119) |
0.0 | 0.3 | GO:0001833 | inner cell mass cell proliferation(GO:0001833) |
0.0 | 0.2 | GO:0070307 | tripartite regional subdivision(GO:0007351) anterior/posterior axis specification, embryo(GO:0008595) lens fiber cell development(GO:0070307) |
0.0 | 0.1 | GO:0051684 | maintenance of Golgi location(GO:0051684) |
0.0 | 0.1 | GO:0006003 | fructose 2,6-bisphosphate metabolic process(GO:0006003) |
0.0 | 0.2 | GO:0070935 | 3'-UTR-mediated mRNA stabilization(GO:0070935) |
0.0 | 0.6 | GO:0035329 | hippo signaling(GO:0035329) |
0.0 | 0.3 | GO:0008340 | determination of adult lifespan(GO:0008340) |
0.0 | 0.1 | GO:0090168 | Golgi reassembly(GO:0090168) |
0.0 | 4.5 | GO:0018105 | peptidyl-serine phosphorylation(GO:0018105) |
0.0 | 0.9 | GO:0016574 | histone ubiquitination(GO:0016574) |
0.0 | 0.2 | GO:0006622 | protein targeting to lysosome(GO:0006622) |
0.0 | 0.3 | GO:0034063 | stress granule assembly(GO:0034063) |
0.0 | 0.3 | GO:0046827 | positive regulation of protein export from nucleus(GO:0046827) |
0.0 | 0.3 | GO:0043171 | peptide catabolic process(GO:0043171) |
Gene overrepresentation in cellular_component category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.3 | 1.2 | GO:0060187 | cell pole(GO:0060187) |
0.2 | 9.2 | GO:0030173 | integral component of Golgi membrane(GO:0030173) |
0.2 | 1.1 | GO:0005890 | sodium:potassium-exchanging ATPase complex(GO:0005890) dendritic spine neck(GO:0044326) |
0.1 | 0.9 | GO:0033503 | HULC complex(GO:0033503) |
0.1 | 0.8 | GO:0071204 | histone pre-mRNA 3'end processing complex(GO:0071204) |
0.1 | 1.1 | GO:0072669 | tRNA-splicing ligase complex(GO:0072669) |
0.1 | 0.6 | GO:0005726 | perichromatin fibrils(GO:0005726) |
0.1 | 2.0 | GO:0097038 | perinuclear endoplasmic reticulum(GO:0097038) |
0.1 | 1.6 | GO:0005865 | striated muscle thin filament(GO:0005865) |
0.1 | 0.5 | GO:0031315 | extrinsic component of mitochondrial outer membrane(GO:0031315) |
0.1 | 0.4 | GO:0045254 | pyruvate dehydrogenase complex(GO:0045254) |
0.1 | 0.2 | GO:0043202 | lysosomal lumen(GO:0043202) |
0.1 | 0.8 | GO:0031527 | filopodium membrane(GO:0031527) |
0.0 | 0.1 | GO:0043540 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex(GO:0043540) |
0.0 | 0.5 | GO:0031258 | lamellipodium membrane(GO:0031258) |
0.0 | 0.6 | GO:0034706 | voltage-gated sodium channel complex(GO:0001518) sodium channel complex(GO:0034706) |
0.0 | 0.2 | GO:0090543 | Flemming body(GO:0090543) |
0.0 | 0.4 | GO:0042622 | photoreceptor outer segment membrane(GO:0042622) |
0.0 | 2.1 | GO:0005791 | rough endoplasmic reticulum(GO:0005791) |
0.0 | 0.1 | GO:0097413 | Lewy body(GO:0097413) |
0.0 | 0.3 | GO:0005640 | nuclear outer membrane(GO:0005640) |
0.0 | 0.2 | GO:0001740 | Barr body(GO:0001740) |
0.0 | 0.2 | GO:0042382 | paraspeckles(GO:0042382) |
0.0 | 0.4 | GO:0005665 | DNA-directed RNA polymerase II, core complex(GO:0005665) |
0.0 | 0.4 | GO:0016235 | aggresome(GO:0016235) |
0.0 | 0.1 | GO:0033588 | Elongator holoenzyme complex(GO:0033588) |
0.0 | 0.6 | GO:1990391 | DNA repair complex(GO:1990391) |
Gene overrepresentation in molecular_function category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
1.2 | 9.3 | GO:0003836 | beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836) |
0.3 | 0.8 | GO:0071207 | histone pre-mRNA stem-loop binding(GO:0071207) |
0.3 | 2.1 | GO:0005004 | GPI-linked ephrin receptor activity(GO:0005004) |
0.2 | 2.5 | GO:0019531 | oxalate transmembrane transporter activity(GO:0019531) |
0.2 | 1.6 | GO:0005523 | tropomyosin binding(GO:0005523) |
0.1 | 1.1 | GO:0103116 | alpha-D-galactofuranose transporter activity(GO:0103116) |
0.1 | 0.5 | GO:0033814 | propanoyl-CoA C-acyltransferase activity(GO:0033814) propionyl-CoA C2-trimethyltridecanoyltransferase activity(GO:0050632) phosphatidylethanolamine transporter activity(GO:1904121) |
0.1 | 0.8 | GO:0035727 | lysophosphatidic acid binding(GO:0035727) |
0.1 | 0.4 | GO:0030292 | protein tyrosine kinase inhibitor activity(GO:0030292) |
0.1 | 0.5 | GO:0046912 | transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912) |
0.1 | 0.6 | GO:0034056 | estrogen response element binding(GO:0034056) |
0.1 | 0.2 | GO:0031686 | A1 adenosine receptor binding(GO:0031686) |
0.1 | 0.4 | GO:0034604 | pyruvate dehydrogenase activity(GO:0004738) pyruvate dehydrogenase [NAD(P)+] activity(GO:0034603) pyruvate dehydrogenase (NAD+) activity(GO:0034604) |
0.1 | 0.4 | GO:0003917 | DNA topoisomerase type I activity(GO:0003917) |
0.1 | 0.2 | GO:0051378 | primary amine oxidase activity(GO:0008131) serotonin binding(GO:0051378) |
0.1 | 0.4 | GO:0052650 | NADP-retinol dehydrogenase activity(GO:0052650) |
0.0 | 1.2 | GO:0009931 | calcium-dependent protein serine/threonine kinase activity(GO:0009931) |
0.0 | 0.2 | GO:0015183 | L-aspartate transmembrane transporter activity(GO:0015183) |
0.0 | 1.6 | GO:0001106 | RNA polymerase II transcription corepressor activity(GO:0001106) |
0.0 | 0.6 | GO:0043522 | leucine zipper domain binding(GO:0043522) |
0.0 | 0.3 | GO:0043495 | protein anchor(GO:0043495) |
0.0 | 0.8 | GO:0017161 | phosphohistidine phosphatase activity(GO:0008969) inositol-1,3,4-trisphosphate 4-phosphatase activity(GO:0017161) NADP phosphatase activity(GO:0019178) 5-amino-6-(5-phosphoribitylamino)uracil phosphatase activity(GO:0043726) phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity(GO:0043813) inositol-1,3,4,5,6-pentakisphosphate 1-phosphatase activity(GO:0052825) inositol-3,4-bisphosphate 4-phosphatase activity(GO:0052828) inositol-1,3,4-trisphosphate 1-phosphatase activity(GO:0052829) inositol-1,3,4,6-tetrakisphosphate 6-phosphatase activity(GO:0052830) inositol-1,3,4,6-tetrakisphosphate 1-phosphatase activity(GO:0052831) phosphatidylinositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052867) IDP phosphatase activity(GO:1990003) |
0.0 | 0.3 | GO:0051959 | dynein light intermediate chain binding(GO:0051959) |
0.0 | 0.1 | GO:0047066 | phospholipid-hydroperoxide glutathione peroxidase activity(GO:0047066) |
0.0 | 0.2 | GO:0015265 | urea channel activity(GO:0015265) |
0.0 | 0.6 | GO:0030553 | cGMP binding(GO:0030553) |
0.0 | 0.3 | GO:0050897 | cobalt ion binding(GO:0050897) |
0.0 | 0.2 | GO:0008568 | microtubule-severing ATPase activity(GO:0008568) |
0.0 | 0.1 | GO:0035515 | oxidative RNA demethylase activity(GO:0035515) |
0.0 | 0.2 | GO:0045125 | bioactive lipid receptor activity(GO:0045125) |
0.0 | 0.9 | GO:0005544 | calcium-dependent phospholipid binding(GO:0005544) |
0.0 | 0.2 | GO:0034951 | pivalyl-CoA mutase activity(GO:0034784) o-hydroxylaminobenzoate mutase activity(GO:0034951) lupeol synthase activity(GO:0042299) beta-amyrin synthase activity(GO:0042300) baruol synthase activity(GO:0080011) |
0.0 | 0.1 | GO:0070095 | fructose-6-phosphate binding(GO:0070095) |
0.0 | 0.2 | GO:0005068 | transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068) |
0.0 | 4.1 | GO:0000287 | magnesium ion binding(GO:0000287) |
0.0 | 0.5 | GO:0005385 | zinc ion transmembrane transporter activity(GO:0005385) |
0.0 | 0.0 | GO:0008109 | N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109) |
0.0 | 0.6 | GO:0042162 | telomeric DNA binding(GO:0042162) |
0.0 | 0.1 | GO:0004526 | ribonuclease P activity(GO:0004526) |