Motif ID: Rorc_Nr1d1

Z-value: 0.510

Transcription factors associated with Rorc_Nr1d1:

Gene SymbolEntrez IDGene Name
Nr1d1 ENSMUSG00000020889.11 Nr1d1
Rorc ENSMUSG00000028150.8 Rorc

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Rorcmm10_v2_chr3_+_94377505_943775270.214.6e-01Click!
Nr1d1mm10_v2_chr11_-_98775333_98775354-0.078.0e-01Click!


Activity profile for motif Rorc_Nr1d1.

activity profile for motif Rorc_Nr1d1


Sorted Z-values histogram for motif Rorc_Nr1d1

Sorted Z-values for motif Rorc_Nr1d1



Network of associatons between targets according to the STRING database.



First level regulatory network of Rorc_Nr1d1

PNG image of the network

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Top targets:


Showing 1 to 20 of 123 entries
PromoterScoreRefseqGene SymbolGene Name
chrX_+_103422010 1.035 ENSMUST00000182089.1
 Gm26992
predicted gene, 26992
chr17_-_24886304 0.719 ENSMUST00000044252.5
 Nubp2
nucleotide binding protein 2
chr17_+_24886643 0.672 ENSMUST00000117890.1
ENSMUST00000168265.1
ENSMUST00000120943.1
ENSMUST00000068508.6
ENSMUST00000119829.1
 Spsb3




splA/ryanodine receptor domain and SOCS box containing 3




chr3_-_101307079 0.539 ENSMUST00000097146.2
 Gm10355
predicted gene 10355
chr7_-_142661858 0.506 ENSMUST00000145896.2
 Igf2
insulin-like growth factor 2
chr1_+_6734827 0.484 ENSMUST00000139838.1
 St18
suppression of tumorigenicity 18
chr11_+_98348404 0.384 ENSMUST00000078694.6
 Ppp1r1b
protein phosphatase 1, regulatory (inhibitor) subunit 1B
chr11_+_94328242 0.336 ENSMUST00000021227.5
 Ankrd40
ankyrin repeat domain 40
chr15_-_65014904 0.327 ENSMUST00000110100.2
 Gm21961
predicted gene, 21961
chr7_+_113207465 0.314 ENSMUST00000047321.7
 Arntl
aryl hydrocarbon receptor nuclear translocator-like
chr2_+_155751117 0.301 ENSMUST00000029140.5
ENSMUST00000132608.1
 Procr

protein C receptor, endothelial

chr7_-_142661305 0.281 ENSMUST00000105936.1
 Igf2
insulin-like growth factor 2
chr11_+_94327984 0.280 ENSMUST00000107818.2
ENSMUST00000051221.6
 Ankrd40

ankyrin repeat domain 40

chrX_-_16911774 0.242 ENSMUST00000040134.7
 Ndp
Norrie disease (pseudoglioma) (human)
chr17_+_33638056 0.238 ENSMUST00000052079.7
 Pram1
PML-RAR alpha-regulated adaptor molecule 1
chr14_-_54577578 0.233 ENSMUST00000054487.8
 Ajuba
ajuba LIM protein
chr7_-_126625676 0.226 ENSMUST00000032961.3
 Nupr1
nuclear protein transcription regulator 1
chr7_+_45705088 0.224 ENSMUST00000080885.3
 Dbp
D site albumin promoter binding protein
chr9_-_30922452 0.215 ENSMUST00000065112.6
 Adamts15
a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 15
chr5_+_64970069 0.212 ENSMUST00000031080.8
 Fam114a1
family with sequence similarity 114, member A1

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 20 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 0.8 GO:0038028 insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028)
0.0 0.8 GO:0016226 iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.1 0.4 GO:0007621 negative regulation of female receptivity(GO:0007621)
0.1 0.3 GO:0090403 oxidative stress-induced premature senescence(GO:0090403)
0.1 0.3 GO:0060316 positive regulation of ryanodine-sensitive calcium-release channel activity(GO:0060316)
0.1 0.2 GO:0035426 extracellular matrix-cell signaling(GO:0035426)
0.1 0.2 GO:0051892 negative regulation of cardioblast differentiation(GO:0051892) dermatome development(GO:0061054) regulation of dermatome development(GO:0061183) negative regulation of dopaminergic neuron differentiation(GO:1904339) regulation of cardiac cell fate specification(GO:2000043)
0.0 0.2 GO:0035331 negative regulation of hippo signaling(GO:0035331)
0.0 0.2 GO:2000194 regulation of female gonad development(GO:2000194)
0.0 0.2 GO:0043313 regulation of neutrophil degranulation(GO:0043313)
0.0 0.2 GO:0071285 cellular response to lithium ion(GO:0071285)
0.0 0.2 GO:2000821 AMPA glutamate receptor clustering(GO:0097113) glutamate receptor clustering(GO:0097688) regulation of grooming behavior(GO:2000821)
0.0 0.1 GO:0060084 regulation of circadian sleep/wake cycle, REM sleep(GO:0042320) circadian sleep/wake cycle, REM sleep(GO:0042747) synaptic transmission involved in micturition(GO:0060084)
0.0 0.1 GO:0033615 mitochondrial proton-transporting ATP synthase complex assembly(GO:0033615)
0.0 0.1 GO:0071105 response to interleukin-9(GO:0071104) response to interleukin-11(GO:0071105)
0.0 0.1 GO:0032811 negative regulation of gamma-aminobutyric acid secretion(GO:0014053) negative regulation of epinephrine secretion(GO:0032811)
0.0 0.1 GO:0046036 GTP biosynthetic process(GO:0006183) CTP biosynthetic process(GO:0006241) CTP metabolic process(GO:0046036)
0.0 0.1 GO:0070475 nucleolus organization(GO:0007000) rRNA base methylation(GO:0070475)
0.0 0.0 GO:0035752 lysosomal lumen pH elevation(GO:0035752)
0.0 0.0 GO:2000297 negative regulation of synapse maturation(GO:2000297)

Gene overrepresentation in cellular_component category:

Showing 1 to 7 of 7 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 0.7 GO:0031616 spindle pole centrosome(GO:0031616)
0.0 0.3 GO:0033391 chromatoid body(GO:0033391)
0.1 0.2 GO:1990851 Wnt-Frizzled-LRP5/6 complex(GO:1990851)
0.1 0.2 GO:1990879 CST complex(GO:1990879)
0.0 0.1 GO:0038039 G-protein coupled receptor heterodimeric complex(GO:0038039)
0.0 0.1 GO:0036195 muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)
0.0 0.1 GO:0005892 acetylcholine-gated channel complex(GO:0005892)

Gene overrepresentation in molecular_function category:

Showing 1 to 14 of 14 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 0.8 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.0 0.7 GO:0051539 4 iron, 4 sulfur cluster binding(GO:0051539)
0.1 0.4 GO:0031752 D3 dopamine receptor binding(GO:0031750) D5 dopamine receptor binding(GO:0031752)
0.1 0.3 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.0 0.3 GO:1900750 glutathione binding(GO:0043295) oligopeptide binding(GO:1900750)
0.1 0.2 GO:0005110 frizzled-2 binding(GO:0005110)
0.0 0.2 GO:0031811 G-protein coupled nucleotide receptor binding(GO:0031811) P2Y1 nucleotide receptor binding(GO:0031812)
0.0 0.2 GO:0045294 alpha-catenin binding(GO:0045294)
0.0 0.2 GO:0010521 telomerase inhibitor activity(GO:0010521)
0.0 0.1 GO:0050693 LBD domain binding(GO:0050693)
0.0 0.1 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.0 0.1 GO:0019841 retinol binding(GO:0019841)
0.0 0.1 GO:0008474 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0 0.1 GO:0042166 acetylcholine binding(GO:0042166)