Motif ID: Rorc_Nr1d1

Z-value: 0.510

Transcription factors associated with Rorc_Nr1d1:

Gene SymbolEntrez IDGene Name
Nr1d1 ENSMUSG00000020889.11 Nr1d1
Rorc ENSMUSG00000028150.8 Rorc

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Rorcmm10_v2_chr3_+_94377505_943775270.214.6e-01Click!
Nr1d1mm10_v2_chr11_-_98775333_98775354-0.078.0e-01Click!





Network of associatons between targets according to the STRING database.



First level regulatory network of Rorc_Nr1d1

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chrX_+_103422010 1.035 ENSMUST00000182089.1
Gm26992
predicted gene, 26992
chr17_-_24886304 0.719 ENSMUST00000044252.5
Nubp2
nucleotide binding protein 2
chr17_+_24886643 0.672 ENSMUST00000117890.1
ENSMUST00000168265.1
ENSMUST00000120943.1
ENSMUST00000068508.6
ENSMUST00000119829.1
Spsb3




splA/ryanodine receptor domain and SOCS box containing 3




chr3_-_101307079 0.539 ENSMUST00000097146.2
Gm10355
predicted gene 10355
chr7_-_142661858 0.506 ENSMUST00000145896.2
Igf2
insulin-like growth factor 2
chr1_+_6734827 0.484 ENSMUST00000139838.1
St18
suppression of tumorigenicity 18
chr11_+_98348404 0.384 ENSMUST00000078694.6
Ppp1r1b
protein phosphatase 1, regulatory (inhibitor) subunit 1B
chr11_+_94328242 0.336 ENSMUST00000021227.5
Ankrd40
ankyrin repeat domain 40
chr15_-_65014904 0.327 ENSMUST00000110100.2
Gm21961
predicted gene, 21961
chr7_+_113207465 0.314 ENSMUST00000047321.7
Arntl
aryl hydrocarbon receptor nuclear translocator-like
chr2_+_155751117 0.301 ENSMUST00000029140.5
ENSMUST00000132608.1
Procr

protein C receptor, endothelial

chr7_-_142661305 0.281 ENSMUST00000105936.1
Igf2
insulin-like growth factor 2
chr11_+_94327984 0.280 ENSMUST00000107818.2
ENSMUST00000051221.6
Ankrd40

ankyrin repeat domain 40

chrX_-_16911774 0.242 ENSMUST00000040134.7
Ndp
Norrie disease (pseudoglioma) (human)
chr17_+_33638056 0.238 ENSMUST00000052079.7
Pram1
PML-RAR alpha-regulated adaptor molecule 1
chr14_-_54577578 0.233 ENSMUST00000054487.8
Ajuba
ajuba LIM protein
chr7_-_126625676 0.226 ENSMUST00000032961.3
Nupr1
nuclear protein transcription regulator 1
chr7_+_45705088 0.224 ENSMUST00000080885.3
Dbp
D site albumin promoter binding protein
chr9_-_30922452 0.215 ENSMUST00000065112.6
Adamts15
a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 15
chr5_+_64970069 0.212 ENSMUST00000031080.8
Fam114a1
family with sequence similarity 114, member A1
chr3_+_55140033 0.179 ENSMUST00000118963.2
ENSMUST00000061099.7
ENSMUST00000153009.1
Ccdc169


coiled-coil domain containing 169


chr7_-_19118357 0.176 ENSMUST00000141380.1
Gm4969
predicted gene 4969
chr1_+_189728264 0.172 ENSMUST00000097442.2
Ptpn14
protein tyrosine phosphatase, non-receptor type 14
chr16_-_44558879 0.169 ENSMUST00000114634.1
Boc
biregional cell adhesion molecule-related/down-regulated by oncogenes (Cdon) binding protein
chr11_+_70030023 0.168 ENSMUST00000143920.2
Dlg4
discs, large homolog 4 (Drosophila)
chr11_-_59290746 0.166 ENSMUST00000010044.7
Wnt3a
wingless-related MMTV integration site 3A
chr11_+_116198853 0.163 ENSMUST00000021130.6
Ten1
TEN1 telomerase capping complex subunit
chr3_-_10208569 0.160 ENSMUST00000029041.4
Fabp4
fatty acid binding protein 4, adipocyte
chr1_-_191907527 0.159 ENSMUST00000069573.5
1700034H15Rik
RIKEN cDNA 1700034H15 gene
chr2_-_5862923 0.157 ENSMUST00000071016.2
Gm13199
predicted gene 13199
chr7_-_126922887 0.149 ENSMUST00000134134.1
ENSMUST00000119781.1
ENSMUST00000121612.2
Tmem219


transmembrane protein 219


chr3_-_107931579 0.148 ENSMUST00000133947.2
ENSMUST00000124215.1
ENSMUST00000106688.1
ENSMUST00000106687.2
Gstm7



glutathione S-transferase, mu 7



chrX_-_102252154 0.147 ENSMUST00000050551.3
Cited1
Cbp/p300-interacting transactivator with Glu/Asp-rich carboxy-terminal domain 1
chr7_-_134232005 0.145 ENSMUST00000134504.1
Adam12
a disintegrin and metallopeptidase domain 12 (meltrin alpha)
chr11_+_88718442 0.145 ENSMUST00000138007.1
C030037D09Rik
RIKEN cDNA C030037D09 gene
chr3_+_79884496 0.138 ENSMUST00000118853.1
Fam198b
family with sequence similarity 198, member B
chr3_-_89764581 0.138 ENSMUST00000029562.3
Chrnb2
cholinergic receptor, nicotinic, beta polypeptide 2 (neuronal)
chr17_+_45686322 0.135 ENSMUST00000024734.7
Mrpl14
mitochondrial ribosomal protein L14
chr3_-_107931817 0.129 ENSMUST00000004137.4
Gstm7
glutathione S-transferase, mu 7
chr5_-_123141067 0.123 ENSMUST00000162697.1
ENSMUST00000160321.1
ENSMUST00000159637.1
AI480526


expressed sequence AI480526


chr12_-_24493656 0.122 ENSMUST00000073088.2
Gm16372
predicted pseudogene 16372
chr4_+_115784799 0.115 ENSMUST00000177280.1
ENSMUST00000176047.1
ENSMUST00000030478.6
Atpaf1


ATP synthase mitochondrial F1 complex assembly factor 1


chr4_+_98546919 0.114 ENSMUST00000030290.7
Inadl
InaD-like (Drosophila)
chr12_-_40248073 0.111 ENSMUST00000169926.1
Ifrd1
interferon-related developmental regulator 1
chr7_-_134232125 0.111 ENSMUST00000127524.1
Adam12
a disintegrin and metallopeptidase domain 12 (meltrin alpha)
chr17_+_24896488 0.110 ENSMUST00000024978.6
Nme3
NME/NM23 nucleoside diphosphate kinase 3
chr6_+_65778988 0.109 ENSMUST00000031976.7
ENSMUST00000081219.7
ENSMUST00000031973.6
ENSMUST00000172638.1
Prdm5



PR domain containing 5



chr17_+_37046555 0.105 ENSMUST00000172789.1
Gabbr1
gamma-aminobutyric acid (GABA) B receptor, 1
chr7_+_13398115 0.104 ENSMUST00000005791.7
Cabp5
calcium binding protein 5
chr6_+_29361410 0.100 ENSMUST00000156163.1
Calu
calumenin
chr14_+_73142490 0.099 ENSMUST00000170370.1
ENSMUST00000164822.1
ENSMUST00000165429.1
Rcbtb2


regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2


chr7_-_79386943 0.093 ENSMUST00000053718.8
ENSMUST00000179243.1
Rlbp1

retinaldehyde binding protein 1

chr6_-_124712131 0.090 ENSMUST00000004379.5
Emg1
EMG1 nucleolar protein homolog (S. cerevisiae)
chr17_-_34628005 0.089 ENSMUST00000166040.2
Ppt2
palmitoyl-protein thioesterase 2
chr15_-_66801577 0.088 ENSMUST00000168589.1
Sla
src-like adaptor
chr7_+_127211608 0.083 ENSMUST00000032910.6
Mylpf
myosin light chain, phosphorylatable, fast skeletal muscle
chr1_+_160195215 0.083 ENSMUST00000135680.1
ENSMUST00000097193.2
Mrps14

mitochondrial ribosomal protein S14

chr13_-_52981027 0.081 ENSMUST00000071065.7
Nfil3
nuclear factor, interleukin 3, regulated
chr4_+_3940747 0.079 ENSMUST00000119403.1
Chchd7
coiled-coil-helix-coiled-coil-helix domain containing 7
chr11_+_68901538 0.078 ENSMUST00000073471.6
ENSMUST00000101014.2
ENSMUST00000128952.1
ENSMUST00000167436.1
Rpl26



ribosomal protein L26



chr2_-_153015331 0.068 ENSMUST00000028972.8
Pdrg1
p53 and DNA damage regulated 1
chr15_+_62037986 0.067 ENSMUST00000182956.1
ENSMUST00000182075.1
ENSMUST00000180432.2
ENSMUST00000181416.2
ENSMUST00000181657.2
Pvt1




plasmacytoma variant translocation 1




chr9_+_65460926 0.067 ENSMUST00000034955.6
Spg21
spastic paraplegia 21 homolog (human)
chr5_+_145084100 0.064 ENSMUST00000124379.1
Arpc1a
actin related protein 2/3 complex, subunit 1A
chr7_+_28693997 0.064 ENSMUST00000108280.1
Fbxo27
F-box protein 27
chr15_-_10485385 0.063 ENSMUST00000168690.1
Brix1
BRX1, biogenesis of ribosomes, homolog (S. cerevisiae)
chr6_-_88874045 0.062 ENSMUST00000038409.5
Podxl2
podocalyxin-like 2
chr7_-_122021143 0.060 ENSMUST00000033160.8
Gga2
golgi associated, gamma adaptin ear containing, ARF binding protein 2
chr10_+_57784859 0.059 ENSMUST00000020024.5
Fabp7
fatty acid binding protein 7, brain
chr8_+_119862239 0.056 ENSMUST00000034287.8
Klhl36
kelch-like 36
chr1_+_86703788 0.052 ENSMUST00000168237.1
ENSMUST00000065694.6
Dis3l2

DIS3 mitotic control homolog (S. cerevisiae)-like 2

chr12_+_100110148 0.052 ENSMUST00000021595.8
Psmc1
protease (prosome, macropain) 26S subunit, ATPase 1
chr11_+_3650253 0.051 ENSMUST00000096441.3
Morc2a
microrchidia 2A
chr11_+_52098681 0.050 ENSMUST00000020608.2
Ppp2ca
protein phosphatase 2 (formerly 2A), catalytic subunit, alpha isoform
chr5_+_145083830 0.049 ENSMUST00000031625.8
Arpc1a
actin related protein 2/3 complex, subunit 1A
chr9_+_46012810 0.049 ENSMUST00000126865.1
Sik3
SIK family kinase 3
chr12_-_72408934 0.048 ENSMUST00000078505.7
Rtn1
reticulon 1
chr6_-_30896735 0.048 ENSMUST00000048774.6
ENSMUST00000166192.1
ENSMUST00000135230.1
Copg2


coatomer protein complex, subunit gamma 2


chr7_-_126585775 0.046 ENSMUST00000084589.4
Cln3
ceroid lipofuscinosis, neuronal 3, juvenile (Batten, Spielmeyer-Vogt disease)
chr15_+_81872309 0.046 ENSMUST00000023116.6
Aco2
aconitase 2, mitochondrial
chr11_-_51635870 0.043 ENSMUST00000001081.3
Rmnd5b
required for meiotic nuclear division 5 homolog B (S. cerevisiae)
chr17_-_34628380 0.043 ENSMUST00000167097.2
Ppt2
palmitoyl-protein thioesterase 2
chr15_-_10485890 0.042 ENSMUST00000169050.1
ENSMUST00000022855.5
Brix1

BRX1, biogenesis of ribosomes, homolog (S. cerevisiae)

chr11_-_51688614 0.039 ENSMUST00000007921.2
0610009B22Rik
RIKEN cDNA 0610009B22 gene
chr15_-_81871883 0.039 ENSMUST00000023117.8
Phf5a
PHD finger protein 5A
chr13_+_21495218 0.038 ENSMUST00000104942.1
AK157302
cDNA sequence AK157302
chr11_+_3649759 0.038 ENSMUST00000140242.1
Morc2a
microrchidia 2A
chrX_+_70385870 0.037 ENSMUST00000053981.5
1110012L19Rik
RIKEN cDNA 1110012L19 gene
chr2_-_91710519 0.037 ENSMUST00000028678.8
ENSMUST00000076803.5
Atg13

autophagy related 13

chrX_-_136203637 0.035 ENSMUST00000151592.1
ENSMUST00000131510.1
ENSMUST00000066819.4
Tceal5


transcription elongation factor A (SII)-like 5


chr17_-_45686214 0.034 ENSMUST00000113523.2
Tmem63b
transmembrane protein 63b
chr12_-_54695829 0.034 ENSMUST00000162106.1
ENSMUST00000160085.1
ENSMUST00000161592.1
ENSMUST00000163433.1
Eapp



E2F-associated phosphoprotein



chr7_-_30559600 0.033 ENSMUST00000043975.4
ENSMUST00000156241.1
Lin37

lin-37 homolog (C. elegans)

chr3_+_90603767 0.032 ENSMUST00000001046.5
ENSMUST00000107330.1
S100a4

S100 calcium binding protein A4

chr8_-_85080679 0.030 ENSMUST00000093357.5
Wdr83
WD repeat domain containing 83
chr14_-_60197173 0.029 ENSMUST00000131670.1
Atp8a2
ATPase, aminophospholipid transporter-like, class I, type 8A, member 2
chr11_+_40733936 0.028 ENSMUST00000127382.1
Nudcd2
NudC domain containing 2
chr11_-_94653964 0.028 ENSMUST00000039949.4
Eme1
essential meiotic endonuclease 1 homolog 1 (S. pombe)
chr6_+_134830145 0.028 ENSMUST00000046303.5
Crebl2
cAMP responsive element binding protein-like 2
chr13_-_8871696 0.026 ENSMUST00000054251.6
ENSMUST00000176813.1
Wdr37

WD repeat domain 37

chr14_+_105258712 0.024 ENSMUST00000138283.1
Ndfip2
Nedd4 family interacting protein 2
chr9_+_77754526 0.023 ENSMUST00000034905.8
Gclc
glutamate-cysteine ligase, catalytic subunit
chr14_-_54864055 0.022 ENSMUST00000142283.2
Homez
homeodomain leucine zipper-encoding gene
chr5_+_144100387 0.022 ENSMUST00000041804.7
Lmtk2
lemur tyrosine kinase 2
chr11_-_98329641 0.021 ENSMUST00000041685.6
Neurod2
neurogenic differentiation 2
chr15_-_11995998 0.020 ENSMUST00000022816.8
Sub1
SUB1 homolog (S. cerevisiae)
chr16_+_22009471 0.019 ENSMUST00000023561.7
Senp2
SUMO/sentrin specific peptidase 2
chr4_+_94739276 0.019 ENSMUST00000073939.6
ENSMUST00000102798.1
Tek

endothelial-specific receptor tyrosine kinase

chr3_-_153944425 0.018 ENSMUST00000150070.1
Acadm
acyl-Coenzyme A dehydrogenase, medium chain
chr3_+_90600203 0.016 ENSMUST00000001047.7
S100a3
S100 calcium binding protein A3
chr15_+_10486008 0.015 ENSMUST00000022856.8
ENSMUST00000100775.3
ENSMUST00000169519.1
Rad1


RAD1 homolog (S. pombe)


chr7_+_114768736 0.015 ENSMUST00000117543.1
Insc
inscuteable homolog (Drosophila)
chr5_-_115484297 0.011 ENSMUST00000112067.1
Sirt4
sirtuin 4
chr1_+_143739551 0.011 ENSMUST00000050491.9
Glrx2
glutaredoxin 2 (thioltransferase)
chr5_-_122779278 0.010 ENSMUST00000111668.3
Camkk2
calcium/calmodulin-dependent protein kinase kinase 2, beta
chr11_+_120673359 0.010 ENSMUST00000135346.1
ENSMUST00000127269.1
ENSMUST00000131727.2
ENSMUST00000149389.1
ENSMUST00000153346.1
Aspscr1




alveolar soft part sarcoma chromosome region, candidate 1 (human)




chr2_+_91710900 0.007 ENSMUST00000142692.1
ENSMUST00000090608.5
Harbi1

harbinger transposase derived 1

chr6_-_97205549 0.006 ENSMUST00000164744.1
ENSMUST00000089287.5
Uba3

ubiquitin-like modifier activating enzyme 3

chr6_+_61180313 0.005 ENSMUST00000126214.1
Ccser1
coiled-coil serine rich 1
chr11_+_114890041 0.004 ENSMUST00000106582.2
ENSMUST00000045151.5
Cd300a

CD300A antigen

chr11_-_116199040 0.002 ENSMUST00000066587.5
Acox1
acyl-Coenzyme A oxidase 1, palmitoyl
chr3_-_103809278 0.002 ENSMUST00000063502.6
ENSMUST00000106832.1
ENSMUST00000106834.1
ENSMUST00000029435.8
Dclre1b



DNA cross-link repair 1B, PSO2 homolog (S. cerevisiae)



chr7_+_46033698 0.000 ENSMUST00000033121.6
Nomo1
nodal modulator 1

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0007621 negative regulation of female receptivity(GO:0007621)
0.1 0.3 GO:0090403 oxidative stress-induced premature senescence(GO:0090403)
0.1 0.8 GO:0038028 insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028)
0.1 0.3 GO:0060316 positive regulation of ryanodine-sensitive calcium-release channel activity(GO:0060316)
0.1 0.2 GO:0035426 extracellular matrix-cell signaling(GO:0035426)
0.1 0.2 GO:0051892 negative regulation of cardioblast differentiation(GO:0051892) dermatome development(GO:0061054) regulation of dermatome development(GO:0061183) negative regulation of dopaminergic neuron differentiation(GO:1904339) regulation of cardiac cell fate specification(GO:2000043)
0.0 0.2 GO:0035331 negative regulation of hippo signaling(GO:0035331)
0.0 0.1 GO:0060084 regulation of circadian sleep/wake cycle, REM sleep(GO:0042320) circadian sleep/wake cycle, REM sleep(GO:0042747) synaptic transmission involved in micturition(GO:0060084)
0.0 0.1 GO:0033615 mitochondrial proton-transporting ATP synthase complex assembly(GO:0033615)
0.0 0.8 GO:0016226 iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.0 0.1 GO:0071105 response to interleukin-9(GO:0071104) response to interleukin-11(GO:0071105)
0.0 0.2 GO:2000194 regulation of female gonad development(GO:2000194)
0.0 0.2 GO:0043313 regulation of neutrophil degranulation(GO:0043313)
0.0 0.2 GO:0071285 cellular response to lithium ion(GO:0071285)
0.0 0.1 GO:0032811 negative regulation of gamma-aminobutyric acid secretion(GO:0014053) negative regulation of epinephrine secretion(GO:0032811)
0.0 0.0 GO:0035752 lysosomal lumen pH elevation(GO:0035752)
0.0 0.1 GO:0046036 GTP biosynthetic process(GO:0006183) CTP biosynthetic process(GO:0006241) CTP metabolic process(GO:0046036)
0.0 0.0 GO:2000297 negative regulation of synapse maturation(GO:2000297)
0.0 0.2 GO:2000821 AMPA glutamate receptor clustering(GO:0097113) glutamate receptor clustering(GO:0097688) regulation of grooming behavior(GO:2000821)
0.0 0.1 GO:0070475 nucleolus organization(GO:0007000) rRNA base methylation(GO:0070475)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:1990851 Wnt-Frizzled-LRP5/6 complex(GO:1990851)
0.1 0.2 GO:1990879 CST complex(GO:1990879)
0.0 0.7 GO:0031616 spindle pole centrosome(GO:0031616)
0.0 0.3 GO:0033391 chromatoid body(GO:0033391)
0.0 0.1 GO:0038039 G-protein coupled receptor heterodimeric complex(GO:0038039)
0.0 0.1 GO:0036195 muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)
0.0 0.1 GO:0005892 acetylcholine-gated channel complex(GO:0005892)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0031752 D3 dopamine receptor binding(GO:0031750) D5 dopamine receptor binding(GO:0031752)
0.1 0.3 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.1 0.2 GO:0005110 frizzled-2 binding(GO:0005110)
0.0 0.8 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.0 0.2 GO:0031811 G-protein coupled nucleotide receptor binding(GO:0031811) P2Y1 nucleotide receptor binding(GO:0031812)
0.0 0.2 GO:0045294 alpha-catenin binding(GO:0045294)
0.0 0.1 GO:0050693 LBD domain binding(GO:0050693)
0.0 0.1 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.0 0.1 GO:0019841 retinol binding(GO:0019841)
0.0 0.2 GO:0010521 telomerase inhibitor activity(GO:0010521)
0.0 0.7 GO:0051539 4 iron, 4 sulfur cluster binding(GO:0051539)
0.0 0.1 GO:0008474 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0 0.1 GO:0042166 acetylcholine binding(GO:0042166)
0.0 0.3 GO:1900750 glutathione binding(GO:0043295) oligopeptide binding(GO:1900750)