Motif ID: Rreb1

Z-value: 0.893


Transcription factors associated with Rreb1:

Gene SymbolEntrez IDGene Name
Rreb1 ENSMUSG00000039087.10 Rreb1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Rreb1mm10_v2_chr13_+_37826225_378263150.087.7e-01Click!


Activity profile for motif Rreb1.

activity profile for motif Rreb1


Sorted Z-values histogram for motif Rreb1

Sorted Z-values for motif Rreb1



Network of associatons between targets according to the STRING database.



First level regulatory network of Rreb1

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr14_+_68083853 1.783 ENSMUST00000022639.7
 Nefl
neurofilament, light polypeptide
chr11_-_89302545 1.604 ENSMUST00000061728.3
 Nog
noggin
chr19_-_12501996 1.472 ENSMUST00000045521.7
 Dtx4
deltex 4 homolog (Drosophila)
chr11_-_12464881 1.307 ENSMUST00000046755.7
ENSMUST00000109651.2
 Cobl

cordon-bleu WH2 repeat

chr6_+_104492790 1.198 ENSMUST00000161446.1
ENSMUST00000161070.1
ENSMUST00000089215.5
 Cntn6


contactin 6


chr6_+_17463927 1.188 ENSMUST00000115442.1
 Met
met proto-oncogene
chr6_+_17463749 1.109 ENSMUST00000115443.1
 Met
met proto-oncogene
chr1_-_124045247 0.931 ENSMUST00000112603.2
 Dpp10
dipeptidylpeptidase 10
chr2_+_67413725 0.859 ENSMUST00000178898.1
 Gm21830
predicted gene, 21830
chr4_-_141598206 0.852 ENSMUST00000131317.1
ENSMUST00000006381.4
ENSMUST00000129602.1
 Fblim1


filamin binding LIM protein 1


chr6_+_17306335 0.842 ENSMUST00000007799.6
ENSMUST00000115456.1
ENSMUST00000115455.2
ENSMUST00000130505.1
 Cav1



caveolin 1, caveolae protein



chr11_+_67586675 0.831 ENSMUST00000108680.1
 Gas7
growth arrest specific 7
chr14_+_70077375 0.795 ENSMUST00000035908.1
 Egr3
early growth response 3
chr6_+_17307272 0.790 ENSMUST00000115454.1
 Cav1
caveolin 1, caveolae protein
chr8_+_76902277 0.778 ENSMUST00000109912.1
ENSMUST00000128862.1
ENSMUST00000109911.1
 Nr3c2


nuclear receptor subfamily 3, group C, member 2


chr6_+_65671590 0.730 ENSMUST00000054351.4
 Ndnf
neuron-derived neurotrophic factor
chr18_-_74961252 0.722 ENSMUST00000066532.4
 Lipg
lipase, endothelial
chr13_+_76579670 0.712 ENSMUST00000126960.1
ENSMUST00000109583.2
 Mctp1

multiple C2 domains, transmembrane 1

chr14_-_34201604 0.706 ENSMUST00000096019.2
 Gprin2
G protein regulated inducer of neurite outgrowth 2
chr6_+_17307040 0.703 ENSMUST00000123439.1
 Cav1
caveolin 1, caveolae protein

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 108 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.6 2.8 GO:1900085 negative regulation of peptidyl-tyrosine autophosphorylation(GO:1900085)
0.3 2.3 GO:0060665 regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665)
0.0 2.1 GO:0007219 Notch signaling pathway(GO:0007219)
0.6 1.8 GO:0045110 intermediate filament bundle assembly(GO:0045110)
0.0 1.7 GO:0090004 positive regulation of establishment of protein localization to plasma membrane(GO:0090004)
0.4 1.6 GO:2000313 fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060825) regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:2000313)
0.1 1.5 GO:0007614 short-term memory(GO:0007614)
0.2 1.3 GO:1900029 collateral sprouting in absence of injury(GO:0048669) positive regulation of ruffle assembly(GO:1900029)
0.2 0.9 GO:0051725 protein de-ADP-ribosylation(GO:0051725)
0.1 0.9 GO:0061042 vascular wound healing(GO:0061042)
0.1 0.9 GO:0033623 regulation of integrin activation(GO:0033623)
0.0 0.9 GO:0006883 cellular sodium ion homeostasis(GO:0006883)
0.1 0.8 GO:0033089 positive regulation of T cell differentiation in thymus(GO:0033089) positive regulation of thymocyte aggregation(GO:2000400)
0.2 0.7 GO:0010986 positive regulation of lipoprotein particle clearance(GO:0010986)
0.1 0.7 GO:0032625 interleukin-21 production(GO:0032625) interleukin-21 secretion(GO:0072619)
0.1 0.7 GO:0071803 positive regulation of podosome assembly(GO:0071803)
0.0 0.7 GO:0045747 positive regulation of Notch signaling pathway(GO:0045747)
0.0 0.7 GO:0046579 positive regulation of Ras protein signal transduction(GO:0046579)
0.2 0.6 GO:2000508 regulation of dendritic cell chemotaxis(GO:2000508) positive regulation of dendritic cell chemotaxis(GO:2000510)
0.0 0.6 GO:0007252 I-kappaB phosphorylation(GO:0007252)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 50 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 2.8 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.0 2.3 GO:0009925 basal plasma membrane(GO:0009925)
0.6 1.8 GO:0033596 TSC1-TSC2 complex(GO:0033596)
0.3 1.3 GO:1990357 terminal web(GO:1990357)
0.0 1.2 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.0 1.2 GO:0005884 actin filament(GO:0005884)
0.0 1.1 GO:0032432 actin filament bundle(GO:0032432)
0.0 0.8 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.0 0.7 GO:0002102 podosome(GO:0002102)
0.1 0.6 GO:0042824 MHC class I peptide loading complex(GO:0042824)
0.0 0.6 GO:0008385 IkappaB kinase complex(GO:0008385)
0.1 0.4 GO:1990131 EGO complex(GO:0034448) Gtr1-Gtr2 GTPase complex(GO:1990131)
0.0 0.4 GO:0044327 dendritic spine head(GO:0044327)
0.0 0.4 GO:0097542 ciliary tip(GO:0097542)
0.0 0.4 GO:0043189 NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562)
0.1 0.3 GO:1990761 growth cone lamellipodium(GO:1990761)
0.0 0.3 GO:0035371 microtubule plus-end(GO:0035371)
0.0 0.3 GO:0043194 axon initial segment(GO:0043194)
0.0 0.3 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 0.3 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 69 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.6 2.8 GO:0070320 inward rectifier potassium channel inhibitor activity(GO:0070320)
0.6 2.3 GO:0005008 hepatocyte growth factor-activated receptor activity(GO:0005008)
0.0 2.3 GO:0051015 actin filament binding(GO:0051015)
0.1 1.8 GO:0043274 phospholipase binding(GO:0043274)
0.1 1.6 GO:0003785 actin monomer binding(GO:0003785)
0.0 1.6 GO:0019955 cytokine binding(GO:0019955)
0.2 1.4 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.0 1.2 GO:0005112 Notch binding(GO:0005112)
0.0 1.1 GO:0042562 hormone binding(GO:0042562)
0.1 1.0 GO:0031005 filamin binding(GO:0031005)
0.1 0.9 GO:0070636 single-strand selective uracil DNA N-glycosylase activity(GO:0017065) nicotinamide riboside hydrolase activity(GO:0070635) nicotinic acid riboside hydrolase activity(GO:0070636) deoxyribonucleoside 5'-monophosphate N-glycosidase activity(GO:0070694)
0.1 0.8 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.2 0.7 GO:0008970 phosphatidylcholine 1-acylhydrolase activity(GO:0008970)
0.2 0.5 GO:0046899 nucleoside triphosphate adenylate kinase activity(GO:0046899)
0.0 0.5 GO:0016717 oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water(GO:0016717)
0.1 0.4 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.0 0.4 GO:0071855 neuropeptide receptor binding(GO:0071855)
0.0 0.4 GO:0017049 GTP-Rho binding(GO:0017049)
0.0 0.4 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 0.4 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)