• All motifs sorted by activity significance
• All samples sorted alphabetically
• Mean activities
• All promoters sorted by FOV

• Activities table
• Activity deltas table
• Regulatory interactions
• Motifs sorted by significance (text)
• Download the whole report

Motif ID: Runx3

Z-value: 0.765

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr15_+_40655020	3.133	ENSMUST00000053467.4	Zfpm2	zinc finger protein, multitype 2
chr3_+_121953213	2.646	ENSMUST00000037958.7 ENSMUST00000128366.1	Arhgap29	Rho GTPase activating protein 29
chr18_-_47368446	1.559	ENSMUST00000076043.6 ENSMUST00000135790.1	Sema6a	sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A
chrX_-_73869804	1.152	ENSMUST00000066576.5 ENSMUST00000114430.1	L1cam	L1 cell adhesion molecule
chr11_+_75532127	1.152	ENSMUST00000127226.1	Slc43a2	solute carrier family 43, member 2
chr11_+_75532099	1.150	ENSMUST00000169547.2	Slc43a2	solute carrier family 43, member 2
chr5_+_21424934	1.114	ENSMUST00000056045.4	Fam185a	family with sequence similarity 185, member A
chr13_-_51734695	1.021	ENSMUST00000110039.1	Sema4d	sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
chr7_+_35802593	1.014	ENSMUST00000052454.2	E130304I02Rik	RIKEN cDNA E130304I02 gene
chr1_-_24100306	0.909	ENSMUST00000027337.8	Fam135a	family with sequence similarity 135, member A
chr6_-_100671126	0.810	ENSMUST00000089245.6 ENSMUST00000113312.2 ENSMUST00000170667.1	Shq1	SHQ1 homolog (S. cerevisiae)
chr10_+_128083273	0.789	ENSMUST00000026459.5	Atp5b	ATP synthase, H+ transporting mitochondrial F1 complex, beta subunit
chr13_-_25020289	0.760	ENSMUST00000021772.2	Mrs2	MRS2 magnesium homeostasis factor homolog (S. cerevisiae)
chr7_-_35802968	0.698	ENSMUST00000061586.4	Zfp507	zinc finger protein 507
chrX_+_99136119	0.659	ENSMUST00000052839.6	Efnb1	ephrin B1
chr17_+_27556613	0.658	ENSMUST00000117600.1 ENSMUST00000114888.3	Hmga1	high mobility group AT-hook 1
chr17_+_27556641	0.654	ENSMUST00000119486.1 ENSMUST00000118599.1	Hmga1	high mobility group AT-hook 1
chr17_+_27556668	0.625	ENSMUST00000117254.1 ENSMUST00000118570.1	Hmga1	high mobility group AT-hook 1
chr10_-_62602261	0.613	ENSMUST00000045866.7	Ddx21	DEAD (Asp-Glu-Ala-Asp) box polypeptide 21
chrX_-_98890781	0.600	ENSMUST00000113826.1 ENSMUST00000033560.2 ENSMUST00000142267.1	Ophn1	oligophrenin 1
chr12_+_26469204	0.591	ENSMUST00000020969.3	Cmpk2	cytidine monophosphate (UMP-CMP) kinase 2, mitochondrial
chr11_-_5762358	0.566	ENSMUST00000120306.1 ENSMUST00000170116.1 ENSMUST00000053427.4 ENSMUST00000118076.1	Urgcp	upregulator of cell proliferation
chr4_-_133672601	0.520	ENSMUST00000062118.4 ENSMUST00000067902.6	Pigv	phosphatidylinositol glycan anchor biosynthesis, class V
chr11_-_23665862	0.508	ENSMUST00000020523.3	Pex13	peroxisomal biogenesis factor 13
chr8_+_27023793	0.489	ENSMUST00000033873.7	Erlin2	ER lipid raft associated 2
chr8_+_4243264	0.475	ENSMUST00000110996.1	Map2k7	mitogen-activated protein kinase kinase 7
chr10_-_81001338	0.468	ENSMUST00000099462.1 ENSMUST00000118233.1	Gng7	guanine nucleotide binding protein (G protein), gamma 7
chr7_+_141216626	0.458	ENSMUST00000141804.1 ENSMUST00000148975.1	Rassf7	Ras association (RalGDS/AF-6) domain family (N-terminal) member 7
chr17_+_8165501	0.450	ENSMUST00000097419.3 ENSMUST00000024636.8	Fgfr1op	Fgfr1 oncogene partner
chr15_+_8169067	0.448	ENSMUST00000110617.1	2410089E03Rik	RIKEN cDNA 2410089E03 gene
chr4_-_120570252	0.436	ENSMUST00000030381.7	Ctps	cytidine 5'-triphosphate synthase
chr3_+_95658771	0.431	ENSMUST00000178686.1	Mcl1	myeloid cell leukemia sequence 1
chr8_-_27128615	0.401	ENSMUST00000033877.4	Brf2	BRF2, subunit of RNA polymerase III transcription initiation factor, BRF1-like
chr9_+_109931774	0.364	ENSMUST00000169851.2	Map4	microtubule-associated protein 4
chr7_-_141437587	0.354	ENSMUST00000172654.1 ENSMUST00000106006.1	Slc25a22	solute carrier family 25 (mitochondrial carrier, glutamate), member 22
chr7_-_78783026	0.351	ENSMUST00000032841.5	Mrpl46	mitochondrial ribosomal protein L46
chr5_+_121397936	0.341	ENSMUST00000042163.8	Naa25	N(alpha)-acetyltransferase 25, NatB auxiliary subunit
chr11_-_70220794	0.335	ENSMUST00000159867.1	Slc16a13	solute carrier family 16 (monocarboxylic acid transporters), member 13
chr11_-_70410010	0.334	ENSMUST00000019065.3 ENSMUST00000135148.1	Pelp1	proline, glutamic acid and leucine rich protein 1
chr9_-_108094459	0.322	ENSMUST00000081309.7	Apeh	acylpeptide hydrolase
chr17_+_35879770	0.306	ENSMUST00000025292.8	Dhx16	DEAH (Asp-Glu-Ala-His) box polypeptide 16
chr4_+_19575139	0.304	ENSMUST00000108253.1 ENSMUST00000029888.3	Rmdn1	regulator of microtubule dynamics 1
chr11_-_70220776	0.303	ENSMUST00000141290.1	Slc16a13	solute carrier family 16 (monocarboxylic acid transporters), member 13
chr11_-_86357570	0.299	ENSMUST00000043624.8	Med13	mediator complex subunit 13
chr5_-_25223153	0.284	ENSMUST00000066954.1	E130116L18Rik	RIKEN cDNA E130116L18 gene
chr3_+_122245557	0.282	ENSMUST00000029769.7	Gclm	glutamate-cysteine ligase, modifier subunit
chr9_+_106429537	0.279	ENSMUST00000059802.6	Rpl29	ribosomal protein L29
chr3_+_122245625	0.278	ENSMUST00000178826.1	Gclm	glutamate-cysteine ligase, modifier subunit
chr13_-_14063395	0.268	ENSMUST00000170957.1	Ggps1	geranylgeranyl diphosphate synthase 1
chr9_+_106429399	0.263	ENSMUST00000150576.1	Rpl29	ribosomal protein L29
chr17_+_30005029	0.257	ENSMUST00000057897.7	Zfand3	zinc finger, AN1-type domain 3
chr6_-_99632376	0.241	ENSMUST00000176255.1	Gm20696	predicted gene 20696
chr13_+_21735055	0.235	ENSMUST00000087714.4	Hist1h4j	histone cluster 1, H4j
chr3_+_95658714	0.233	ENSMUST00000037947.8	Mcl1	myeloid cell leukemia sequence 1
chr5_+_25222862	0.214	ENSMUST00000045737.7	Galnt11	UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 11
chr4_-_117887279	0.210	ENSMUST00000132073.1	Atp6v0b	ATPase, H+ transporting, lysosomal V0 subunit B
chr11_+_75679259	0.198	ENSMUST00000017920.7 ENSMUST00000108426.1 ENSMUST00000108425.1 ENSMUST00000093115.3	Crk	v-crk sarcoma virus CT10 oncogene homolog (avian)
chr8_-_54724474	0.197	ENSMUST00000175915.1	Wdr17	WD repeat domain 17
chr4_-_117887292	0.194	ENSMUST00000150204.1 ENSMUST00000147845.1 ENSMUST00000036380.7 ENSMUST00000136596.1	Atp6v0b	ATPase, H+ transporting, lysosomal V0 subunit B
chr13_-_76018524	0.177	ENSMUST00000050997.1 ENSMUST00000179078.1 ENSMUST00000167271.1	Rfesd	Rieske (Fe-S) domain containing
chr11_-_32267547	0.167	ENSMUST00000109389.2 ENSMUST00000129010.1 ENSMUST00000020530.5	Nprl3	nitrogen permease regulator-like 3
chr1_+_159232299	0.167	ENSMUST00000076894.5	Rfwd2	ring finger and WD repeat domain 2
chr14_-_72709534	0.166	ENSMUST00000162478.1	Fndc3a	fibronectin type III domain containing 3A
chr11_+_101009452	0.157	ENSMUST00000044721.6 ENSMUST00000103110.3 ENSMUST00000168757.2	Atp6v0a1	ATPase, H+ transporting, lysosomal V0 subunit A1
chr11_-_70220969	0.154	ENSMUST00000060010.2	Slc16a13	solute carrier family 16 (monocarboxylic acid transporters), member 13
chr18_-_77713978	0.146	ENSMUST00000074653.4	8030462N17Rik	RIKEN cDNA 8030462N17 gene
chr7_+_28808795	0.126	ENSMUST00000172529.1	Hnrnpl	heterogeneous nuclear ribonucleoprotein L
chr6_-_136804414	0.123	ENSMUST00000179285.1	Hist4h4	histone cluster 4, H4
chr4_-_70410422	0.118	ENSMUST00000144099.1	Cdk5rap2	CDK5 regulatory subunit associated protein 2
chr7_-_142095266	0.113	ENSMUST00000039926.3	Dusp8	dual specificity phosphatase 8
chr12_+_98628126	0.109	ENSMUST00000048402.5 ENSMUST00000101144.3 ENSMUST00000101146.3	Spata7	spermatogenesis associated 7
chr8_+_71908595	0.109	ENSMUST00000131544.1 ENSMUST00000110002.1 ENSMUST00000125802.1	Zfp617 Zfp882	zinc finger protein 617 zinc finger protein 882
chr7_+_78783119	0.105	ENSMUST00000032840.4	Mrps11	mitochondrial ribosomal protein S11
chr9_+_109931458	0.085	ENSMUST00000072772.5 ENSMUST00000035055.8	Map4	microtubule-associated protein 4
chr18_-_34651703	0.054	ENSMUST00000025228.5 ENSMUST00000133181.1	Cdc23	CDC23 cell division cycle 23
chr16_-_94526830	0.052	ENSMUST00000023615.6	Dscr3	Down syndrome critical region gene 3
chr9_+_109931863	0.042	ENSMUST00000165876.1	Map4	microtubule-associated protein 4
chr7_+_3617357	0.032	ENSMUST00000076657.4 ENSMUST00000108644.1	Ndufa3	NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 3
chr12_-_98259416	0.029	ENSMUST00000021390.7	Galc	galactosylceramidase
chr2_-_50296680	0.023	ENSMUST00000144143.1 ENSMUST00000102769.4 ENSMUST00000133768.1	Mmadhc	methylmalonic aciduria (cobalamin deficiency) cblD type, with homocystinuria
chr9_-_78481724	0.007	ENSMUST00000042235.8	Eef1a1	eukaryotic translation elongation factor 1 alpha 1

Gene overrepresentation in biological_process category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.0	3.1	GO:0003195	tricuspid valve development(GO:0003175) tricuspid valve morphogenesis(GO:0003186) tricuspid valve formation(GO:0003195) right ventricular cardiac muscle tissue morphogenesis(GO:0003221)
0.3	0.8	GO:0090071	negative regulation of ribosome biogenesis(GO:0090071)
0.3	1.0	GO:1900220	negative regulation of alkaline phosphatase activity(GO:0010693) semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis(GO:1900220)
0.2	0.8	GO:0006933	negative regulation of cell adhesion involved in substrate-bound cell migration(GO:0006933)
0.2	0.6	GO:0046077	dUDP biosynthetic process(GO:0006227) pyrimidine nucleoside diphosphate biosynthetic process(GO:0009139) pyrimidine deoxyribonucleoside diphosphate metabolic process(GO:0009196) pyrimidine deoxyribonucleoside diphosphate biosynthetic process(GO:0009197) dUDP metabolic process(GO:0046077)
0.2	0.7	GO:1903378	positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903378)
0.1	1.2	GO:0033631	cell-cell adhesion mediated by integrin(GO:0033631)
0.1	0.5	GO:0001561	fatty acid alpha-oxidation(GO:0001561)
0.1	0.5	GO:0051012	microtubule sliding(GO:0051012) negative regulation of nonmotile primary cilium assembly(GO:1902856)
0.1	0.4	GO:1904491	protein localization to ciliary transition zone(GO:1904491)
0.1	1.6	GO:2001224	positive regulation of neuron migration(GO:2001224)
0.1	0.6	GO:0051409	response to nitrosative stress(GO:0051409)
0.1	0.5	GO:0045541	negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206)
0.0	0.3	GO:0017196	N-terminal peptidyl-methionine acetylation(GO:0017196)
0.0	0.8	GO:0015693	magnesium ion transport(GO:0015693)
0.0	0.5	GO:0007168	receptor guanylyl cyclase signaling pathway(GO:0007168)
0.0	0.4	GO:0046036	CTP biosynthetic process(GO:0006241) CTP metabolic process(GO:0046036)
0.0	0.5	GO:2000671	regulation of motor neuron apoptotic process(GO:2000671)
0.0	1.9	GO:0006284	base-excision repair(GO:0006284)
0.0	0.8	GO:0035873	lactate transport(GO:0015727) lactate transmembrane transport(GO:0035873) plasma membrane lactate transport(GO:0035879)
0.0	0.7	GO:0031295	lymphocyte costimulation(GO:0031294) T cell costimulation(GO:0031295)
0.0	2.7	GO:0015807	L-amino acid transport(GO:0015807)
0.0	0.6	GO:0007035	vacuolar acidification(GO:0007035)
0.0	0.2	GO:0018243	protein O-linked glycosylation via threonine(GO:0018243)
0.0	0.1	GO:1903546	protein localization to photoreceptor outer segment(GO:1903546)
0.0	0.2	GO:0071941	nitrate metabolic process(GO:0042126) nitrogen cycle metabolic process(GO:0071941)
0.0	0.4	GO:0034453	microtubule anchoring(GO:0034453)
0.0	0.6	GO:0043330	response to exogenous dsRNA(GO:0043330)
0.0	0.3	GO:0055090	acylglycerol homeostasis(GO:0055090) triglyceride homeostasis(GO:0070328)
0.0	0.1	GO:1902416	positive regulation of mRNA binding(GO:1902416) positive regulation of RNA binding(GO:1905216)
0.0	0.6	GO:0048488	synaptic vesicle endocytosis(GO:0048488)
0.0	0.5	GO:0006506	GPI anchor biosynthetic process(GO:0006506)
0.0	0.2	GO:0035020	regulation of Rac protein signal transduction(GO:0035020)
0.0	0.3	GO:0071391	cellular response to estrogen stimulus(GO:0071391)

Gene overrepresentation in cellular_component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	1.9	GO:0035985	senescence-associated heterochromatin focus(GO:0035985)
0.2	0.6	GO:0017109	glutamate-cysteine ligase complex(GO:0017109)
0.1	0.8	GO:0045261	mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275) proton-transporting ATP synthase complex, catalytic core F(1)(GO:0045261)
0.1	0.7	GO:0097136	Bcl-2 family protein complex(GO:0097136)
0.1	0.6	GO:0000220	vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.1	0.5	GO:0031501	mannosyltransferase complex(GO:0031501)
0.0	0.2	GO:1990130	Iml1 complex(GO:1990130)
0.0	0.5	GO:0042788	polysomal ribosome(GO:0042788)
0.0	0.3	GO:0031414	N-terminal protein acetyltransferase complex(GO:0031414)
0.0	1.2	GO:0044295	axonal growth cone(GO:0044295)
0.0	0.5	GO:0005779	integral component of peroxisomal membrane(GO:0005779)
0.0	0.3	GO:0035327	transcriptionally active chromatin(GO:0035327)
0.0	0.4	GO:0035869	ciliary transition zone(GO:0035869)
0.0	0.1	GO:0097431	mitotic spindle pole(GO:0097431)

Gene overrepresentation in molecular_function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	1.2	GO:0033691	sialic acid binding(GO:0033691)
0.2	1.9	GO:0051575	5'-deoxyribose-5-phosphate lyase activity(GO:0051575)
0.2	0.6	GO:0004127	cytidylate kinase activity(GO:0004127) uridylate kinase activity(GO:0009041)
0.2	0.6	GO:0004357	glutamate-cysteine ligase activity(GO:0004357)
0.1	0.4	GO:0030292	protein tyrosine kinase inhibitor activity(GO:0030292)
0.1	0.4	GO:0003883	CTP synthase activity(GO:0003883)
0.1	0.3	GO:0048045	4-hydroxybenzoate octaprenyltransferase activity(GO:0008412) protoheme IX farnesyltransferase activity(GO:0008495) (S)-2,3-di-O-geranylgeranylglyceryl phosphate synthase activity(GO:0043888) cadaverine aminopropyltransferase activity(GO:0043918) agmatine aminopropyltransferase activity(GO:0043919) 1,4-dihydroxy-2-naphthoate octaprenyltransferase activity(GO:0046428) trans-pentaprenyltranstransferase activity(GO:0048045) ATP dimethylallyltransferase activity(GO:0052622) ADP dimethylallyltransferase activity(GO:0052623)
0.1	0.6	GO:0097322	7SK snRNA binding(GO:0097322)
0.1	0.7	GO:0051434	BH3 domain binding(GO:0051434)
0.1	2.6	GO:0030215	semaphorin receptor binding(GO:0030215)
0.1	0.8	GO:0046933	proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.1	0.2	GO:0098809	nitrite reductase activity(GO:0098809)
0.1	0.5	GO:0000268	peroxisome targeting sequence binding(GO:0000268)
0.1	2.3	GO:0015175	neutral amino acid transmembrane transporter activity(GO:0015175)
0.0	0.8	GO:0015129	lactate transmembrane transporter activity(GO:0015129)
0.0	0.8	GO:0015095	magnesium ion transmembrane transporter activity(GO:0015095)
0.0	0.4	GO:0008553	hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0	0.5	GO:0008545	JUN kinase kinase activity(GO:0008545)
0.0	0.3	GO:0004596	peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0	0.4	GO:0005313	L-glutamate transmembrane transporter activity(GO:0005313)
0.0	3.1	GO:0001078	transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0	0.6	GO:0035255	ionotropic glutamate receptor binding(GO:0035255)
0.0	2.6	GO:0030165	PDZ domain binding(GO:0030165)
0.0	0.9	GO:0046875	ephrin receptor binding(GO:0046875)
0.0	0.3	GO:0008242	omega peptidase activity(GO:0008242)
0.0	0.1	GO:1990715	mRNA CDS binding(GO:1990715)
0.0	0.2	GO:0036442	hydrogen-exporting ATPase activity(GO:0036442) ATPase activity, coupled to transmembrane movement of ions, rotational mechanism(GO:0044769) proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.0	0.2	GO:0004653	polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0	0.5	GO:0035496	UDP-glucose:glycoprotein glucosyltransferase activity(GO:0003980) O antigen polymerase activity(GO:0008755) lipopolysaccharide-1,6-galactosyltransferase activity(GO:0008921) cellulose synthase activity(GO:0016759) 9-phenanthrol UDP-glucuronosyltransferase activity(GO:0018715) 1-phenanthrol glycosyltransferase activity(GO:0018716) 9-phenanthrol glycosyltransferase activity(GO:0018717) 1,2-dihydroxy-phenanthrene glycosyltransferase activity(GO:0018718) phenanthrol glycosyltransferase activity(GO:0019112) alpha-1,2-galactosyltransferase activity(GO:0031278) dolichyl pyrophosphate Man7GlcNAc2 alpha-1,3-glucosyltransferase activity(GO:0033556) endogalactosaminidase activity(GO:0033931) lipopolysaccharide-1,5-galactosyltransferase activity(GO:0035496) dolichyl pyrophosphate Glc1Man9GlcNAc2 alpha-1,3-glucosyltransferase activity(GO:0042283) inositol phosphoceramide synthase activity(GO:0045140) alpha-(1->3)-fucosyltransferase activity(GO:0046920) indole-3-butyrate beta-glucosyltransferase activity(GO:0052638) salicylic acid glucosyltransferase (ester-forming) activity(GO:0052639) salicylic acid glucosyltransferase (glucoside-forming) activity(GO:0052640) benzoic acid glucosyltransferase activity(GO:0052641) chondroitin hydrolase activity(GO:0052757) dolichyl-pyrophosphate Man7GlcNAc2 alpha-1,6-mannosyltransferase activity(GO:0052824) cytokinin 9-beta-glucosyltransferase activity(GO:0080062)

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