Motif ID: Rxrb

Z-value: 0.641


Transcription factors associated with Rxrb:

Gene SymbolEntrez IDGene Name
Rxrb ENSMUSG00000039656.10 Rxrb

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Rxrbmm10_v2_chr17_+_34032348_340324010.516.1e-02Click!


Activity profile for motif Rxrb.

activity profile for motif Rxrb


Sorted Z-values histogram for motif Rxrb

Sorted Z-values for motif Rxrb



Network of associatons between targets according to the STRING database.



First level regulatory network of Rxrb

PNG image of the network

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Top targets:


Showing 1 to 20 of 121 entries
PromoterScoreRefseqGene SymbolGene Name
chr1_-_140183404 1.934 ENSMUST00000066859.6
ENSMUST00000111976.2
 Cfh

complement component factor h

chr12_+_119945957 1.629 ENSMUST00000058644.8
 Tmem196
transmembrane protein 196
chr5_-_134747241 1.518 ENSMUST00000015138.9
 Eln
elastin
chr1_-_140183283 1.328 ENSMUST00000111977.1
 Cfh
complement component factor h
chr4_+_136143497 1.176 ENSMUST00000008016.2
 Id3
inhibitor of DNA binding 3
chrX_+_10485121 1.143 ENSMUST00000076354.6
ENSMUST00000115526.1
 Tspan7

tetraspanin 7

chr1_+_84839833 1.138 ENSMUST00000097672.3
 Fbxo36
F-box protein 36
chr5_+_47984571 0.946 ENSMUST00000174313.1
 Slit2
slit homolog 2 (Drosophila)
chr15_-_78529617 0.858 ENSMUST00000023075.8
 C1qtnf6
C1q and tumor necrosis factor related protein 6
chr10_-_53647080 0.809 ENSMUST00000169866.1
 Fam184a
family with sequence similarity 184, member A
chrX_+_99042581 0.796 ENSMUST00000036606.7
 Stard8
START domain containing 8
chr14_+_20929416 0.793 ENSMUST00000022369.7
 Vcl
vinculin
chr1_+_167618246 0.778 ENSMUST00000111380.1
 Rxrg
retinoid X receptor gamma
chr4_-_117178726 0.760 ENSMUST00000153953.1
ENSMUST00000106436.1
 Kif2c

kinesin family member 2C

chr11_-_23519181 0.758 ENSMUST00000020527.5
 1700093K21Rik
RIKEN cDNA 1700093K21 gene
chr5_-_116422858 0.747 ENSMUST00000036991.4
 Hspb8
heat shock protein 8
chr15_-_79285502 0.718 ENSMUST00000165408.1
 Baiap2l2
BAI1-associated protein 2-like 2
chr5_+_110839973 0.711 ENSMUST00000066160.1
 Chek2
checkpoint kinase 2
chr19_-_57008187 0.673 ENSMUST00000118800.1
ENSMUST00000111584.2
ENSMUST00000122359.1
ENSMUST00000148049.1
 Afap1l2



actin filament associated protein 1-like 2



chr10_-_88146867 0.672 ENSMUST00000164121.1
ENSMUST00000164803.1
ENSMUST00000168163.1
ENSMUST00000048518.9
 Parpbp



PARP1 binding protein




Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 40 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.5 3.3 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.1 1.7 GO:0010388 cullin deneddylation(GO:0010388)
0.0 1.5 GO:0043149 contractile actin filament bundle assembly(GO:0030038) stress fiber assembly(GO:0043149)
0.0 1.2 GO:0045662 negative regulation of myoblast differentiation(GO:0045662)
0.0 1.1 GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.3 0.9 GO:0050929 corticospinal neuron axon guidance through spinal cord(GO:0021972) positive regulation of negative chemotaxis(GO:0050924) induction of negative chemotaxis(GO:0050929) negative regulation of mononuclear cell migration(GO:0071676) negative regulation of retinal ganglion cell axon guidance(GO:0090260)
0.0 0.9 GO:0010614 negative regulation of cardiac muscle hypertrophy(GO:0010614)
0.2 0.8 GO:0030951 establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
0.0 0.8 GO:0090136 epithelial cell-cell adhesion(GO:0090136)
0.0 0.8 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.0 0.8 GO:0070208 protein heterotrimerization(GO:0070208)
0.0 0.8 GO:1901522 positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus(GO:1901522)
0.2 0.7 GO:1903463 mitotic cell cycle phase(GO:0098763) regulation of mitotic cell cycle DNA replication(GO:1903463)
0.1 0.7 GO:2000042 negative regulation of double-strand break repair via homologous recombination(GO:2000042)
0.1 0.7 GO:0051764 actin crosslink formation(GO:0051764)
0.0 0.7 GO:0045742 positive regulation of epidermal growth factor receptor signaling pathway(GO:0045742)
0.2 0.6 GO:1903795 regulation of inorganic anion transmembrane transport(GO:1903795)
0.1 0.6 GO:0034316 negative regulation of Arp2/3 complex-mediated actin nucleation(GO:0034316)
0.0 0.6 GO:0007190 activation of adenylate cyclase activity(GO:0007190)
0.1 0.4 GO:0060854 patterning of lymph vessels(GO:0060854)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 22 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 3.0 GO:0072562 blood microparticle(GO:0072562)
0.0 1.7 GO:0008180 COP9 signalosome(GO:0008180)
0.0 1.7 GO:0016605 PML body(GO:0016605)
0.5 1.5 GO:0071953 elastic fiber(GO:0071953)
0.0 1.1 GO:0005581 collagen trimer(GO:0005581)
0.0 1.0 GO:0000407 pre-autophagosomal structure(GO:0000407)
0.0 0.9 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.1 0.8 GO:0005916 fascia adherens(GO:0005916)
0.0 0.8 GO:0005871 kinesin complex(GO:0005871)
0.1 0.7 GO:0071439 clathrin complex(GO:0071439)
0.0 0.6 GO:0034707 chloride channel complex(GO:0034707)
0.0 0.6 GO:0030131 clathrin adaptor complex(GO:0030131)
0.0 0.5 GO:0001739 sex chromatin(GO:0001739)
0.0 0.4 GO:0031080 nuclear pore outer ring(GO:0031080)
0.0 0.4 GO:0031011 Ino80 complex(GO:0031011)
0.0 0.4 GO:0035631 CD40 receptor complex(GO:0035631)
0.1 0.3 GO:0031088 platelet dense granule membrane(GO:0031088)
0.0 0.3 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.3 GO:0005779 integral component of peroxisomal membrane(GO:0005779)
0.0 0.2 GO:0002102 podosome(GO:0002102)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 24 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.1 3.3 GO:0001851 complement component C3b binding(GO:0001851)
0.0 1.5 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 1.2 GO:0005504 fatty acid binding(GO:0005504)
0.1 0.9 GO:0048495 Roundabout binding(GO:0048495)
0.1 0.8 GO:0004886 9-cis retinoic acid receptor activity(GO:0004886)
0.1 0.8 GO:0070181 small ribosomal subunit rRNA binding(GO:0070181)
0.1 0.8 GO:0045294 alpha-catenin binding(GO:0045294)
0.1 0.7 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
0.0 0.7 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.1 0.6 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.1 0.6 GO:0015245 fatty acid transporter activity(GO:0015245)
0.0 0.6 GO:0016500 protein-hormone receptor activity(GO:0016500)
0.1 0.5 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.5 GO:0097027 ubiquitin-protein transferase activator activity(GO:0097027)
0.0 0.5 GO:0051010 microtubule plus-end binding(GO:0051010)
0.1 0.4 GO:0004301 epoxide hydrolase activity(GO:0004301)
0.0 0.4 GO:0001224 RNA polymerase II transcription cofactor binding(GO:0001224)
0.0 0.4 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 0.3 GO:0008601 protein phosphatase type 2A regulator activity(GO:0008601)
0.0 0.3 GO:0070182 DNA polymerase binding(GO:0070182)