Motif ID: Scrt2

Z-value: 1.920


Transcription factors associated with Scrt2:

Gene SymbolEntrez IDGene Name
Scrt2 ENSMUSG00000060257.2 Scrt2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Scrt2mm10_v2_chr2_+_152081529_152081624-0.968.5e-08Click!


Activity profile for motif Scrt2.

activity profile for motif Scrt2


Sorted Z-values histogram for motif Scrt2

Sorted Z-values for motif Scrt2



Network of associatons between targets according to the STRING database.



First level regulatory network of Scrt2

PNG image of the network

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Top targets:


Showing 1 to 20 of 103 entries
PromoterScoreRefseqGene SymbolGene Name
chr16_+_42907563 7.639 ENSMUST00000151244.1
ENSMUST00000114694.2
Zbtb20

zinc finger and BTB domain containing 20

chr7_+_126847908 7.584 ENSMUST00000147257.1
ENSMUST00000139174.1
Doc2a

double C2, alpha

chr11_+_111066154 7.337 ENSMUST00000042970.2
Kcnj2
potassium inwardly-rectifying channel, subfamily J, member 2
chr3_-_53657339 6.349 ENSMUST00000091137.4
Frem2
Fras1 related extracellular matrix protein 2
chr5_+_118169712 6.163 ENSMUST00000054836.6
Hrk
harakiri, BCL2 interacting protein (contains only BH3 domain)
chr8_+_76902277 6.138 ENSMUST00000109912.1
ENSMUST00000128862.1
ENSMUST00000109911.1
Nr3c2


nuclear receptor subfamily 3, group C, member 2


chr17_-_25570678 5.951 ENSMUST00000025003.3
ENSMUST00000173447.1
Sox8

SRY-box containing gene 8

chr18_-_82406777 5.787 ENSMUST00000065224.6
Galr1
galanin receptor 1
chr6_-_23839137 5.717 ENSMUST00000166458.2
ENSMUST00000142913.2
ENSMUST00000115357.1
ENSMUST00000069074.7
ENSMUST00000115361.2
ENSMUST00000018122.7
ENSMUST00000115355.1
ENSMUST00000115356.2
Cadps2







Ca2+-dependent activator protein for secretion 2







chr15_+_34306666 5.136 ENSMUST00000163455.2
ENSMUST00000022947.5
Matn2

matrilin 2

chr15_-_71727815 5.118 ENSMUST00000022953.8
Fam135b
family with sequence similarity 135, member B
chr12_-_40037387 4.976 ENSMUST00000146905.1
Arl4a
ADP-ribosylation factor-like 4A
chr7_+_81523531 4.802 ENSMUST00000181903.1
2900076A07Rik
RIKEN cDNA 2900076A07 gene
chr12_-_4592927 4.623 ENSMUST00000170816.1
Gm3625
predicted gene 3625
chrX_-_101085352 4.469 ENSMUST00000101362.1
ENSMUST00000073927.4
Slc7a3

solute carrier family 7 (cationic amino acid transporter, y+ system), member 3

chr8_-_71537402 4.138 ENSMUST00000051672.7
Bst2
bone marrow stromal cell antigen 2
chr9_+_94669876 3.690 ENSMUST00000033463.9
Slc9a9
solute carrier family 9 (sodium/hydrogen exchanger), member 9
chr11_-_100355383 3.501 ENSMUST00000146878.2
Hap1
huntingtin-associated protein 1
chr7_+_81523555 3.438 ENSMUST00000180385.1
ENSMUST00000180879.1
ENSMUST00000181164.1
ENSMUST00000181264.1
2900076A07Rik



RIKEN cDNA 2900076A07 gene



chr2_-_60881360 3.417 ENSMUST00000164147.1
ENSMUST00000112509.1
Rbms1

RNA binding motif, single stranded interacting protein 1


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 58 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.3 8.8 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.2 7.6 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
1.5 7.3 GO:0086013 membrane repolarization during cardiac muscle cell action potential(GO:0086013)
1.2 6.2 GO:0051365 cellular response to potassium ion starvation(GO:0051365)
0.3 6.1 GO:0006883 cellular sodium ion homeostasis(GO:0006883)
2.0 6.0 GO:0072034 renal vesicle induction(GO:0072034)
1.9 5.8 GO:0051464 positive regulation of cortisol secretion(GO:0051464)
0.1 5.1 GO:0048678 response to axon injury(GO:0048678)
0.1 5.0 GO:0050873 brown fat cell differentiation(GO:0050873)
0.8 4.8 GO:0051461 regulation of corticotropin secretion(GO:0051459) positive regulation of corticotropin secretion(GO:0051461)
0.0 4.8 GO:0048839 inner ear development(GO:0048839)
0.9 4.5 GO:0015819 lysine transport(GO:0015819)
0.2 4.5 GO:0016082 synaptic vesicle priming(GO:0016082)
1.0 4.1 GO:1901252 regulation of intracellular transport of viral material(GO:1901252)
0.5 3.7 GO:1990118 sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.9 3.5 GO:0032901 positive regulation of neurotrophin production(GO:0032901)
0.2 3.4 GO:0034142 toll-like receptor 4 signaling pathway(GO:0034142)
0.5 3.2 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
0.3 3.1 GO:0045217 cell-cell junction maintenance(GO:0045217)
0.4 2.9 GO:0071699 olfactory placode formation(GO:0030910) olfactory placode development(GO:0071698) olfactory placode morphogenesis(GO:0071699)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 30 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 10.1 GO:0005604 basement membrane(GO:0005604)
0.0 8.5 GO:0098793 presynapse(GO:0098793)
0.2 7.3 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.0 7.1 GO:0005887 integral component of plasma membrane(GO:0005887)
0.1 5.7 GO:0042734 presynaptic membrane(GO:0042734)
0.0 5.3 GO:0044798 nuclear transcription factor complex(GO:0044798)
0.0 4.9 GO:0043235 receptor complex(GO:0043235)
1.2 4.8 GO:0017071 intracellular cyclic nucleotide activated cation channel complex(GO:0017071)
0.0 4.1 GO:0031225 anchored component of membrane(GO:0031225)
0.0 3.7 GO:0055037 recycling endosome(GO:0055037)
0.1 3.5 GO:0005776 autophagosome(GO:0005776)
0.6 3.4 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.1 3.3 GO:0005913 cell-cell adherens junction(GO:0005913)
0.1 3.2 GO:0030667 secretory granule membrane(GO:0030667)
0.1 2.9 GO:0043034 costamere(GO:0043034)
0.5 2.8 GO:0061689 tricellular tight junction(GO:0061689)
0.1 2.8 GO:0030665 clathrin-coated vesicle membrane(GO:0030665)
0.6 2.5 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.0 2.4 GO:0005777 peroxisome(GO:0005777) microbody(GO:0042579)
0.4 1.8 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 43 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.3 11.4 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 8.9 GO:0005509 calcium ion binding(GO:0005509)
1.5 7.3 GO:0086008 voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization(GO:0086008)
0.1 6.1 GO:0004879 RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879) transcription factor activity, direct ligand regulated sequence-specific DNA binding(GO:0098531)
0.1 6.0 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
1.9 5.8 GO:0004966 galanin receptor activity(GO:0004966)
0.0 5.6 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
1.0 4.8 GO:0005052 peroxisome matrix targeting signal-1 binding(GO:0005052)
0.1 4.6 GO:0005518 collagen binding(GO:0005518)
0.6 4.5 GO:0015189 L-ornithine transmembrane transporter activity(GO:0000064) arginine transmembrane transporter activity(GO:0015181) L-lysine transmembrane transporter activity(GO:0015189)
0.0 4.5 GO:0003924 GTPase activity(GO:0003924)
0.3 4.1 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 3.8 GO:0052689 carboxylic ester hydrolase activity(GO:0052689)
0.5 3.7 GO:0005451 monovalent cation:proton antiporter activity(GO:0005451) sodium:proton antiporter activity(GO:0015385) potassium:proton antiporter activity(GO:0015386)
0.4 3.5 GO:0048403 brain-derived neurotrophic factor binding(GO:0048403)
0.2 3.4 GO:0001530 lipopolysaccharide binding(GO:0001530)
0.0 3.3 GO:0008013 beta-catenin binding(GO:0008013)
0.1 3.2 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.2 2.8 GO:0030228 lipoprotein particle receptor activity(GO:0030228)
0.9 2.6 GO:0019002 GMP binding(GO:0019002)