Motif ID: Scrt2
Z-value: 1.920
Transcription factors associated with Scrt2:
Gene Symbol | Entrez ID | Gene Name |
---|---|---|
Scrt2 | ENSMUSG00000060257.2 | Scrt2 |
Activity-expression correlation:
Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
---|---|---|---|---|
Scrt2 | mm10_v2_chr2_+_152081529_152081624 | -0.96 | 8.5e-08 | Click! |
Top targets:
Gene overrepresentation in biological_process category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
2.0 | 6.0 | GO:0072034 | renal vesicle induction(GO:0072034) |
1.9 | 5.8 | GO:0051464 | positive regulation of cortisol secretion(GO:0051464) |
1.5 | 7.3 | GO:0086013 | membrane repolarization during cardiac muscle cell action potential(GO:0086013) |
1.2 | 6.2 | GO:0051365 | cellular response to potassium ion starvation(GO:0051365) |
1.0 | 4.1 | GO:1901252 | regulation of intracellular transport of viral material(GO:1901252) |
0.9 | 2.8 | GO:1904274 | tricellular tight junction assembly(GO:1904274) |
0.9 | 4.5 | GO:0015819 | lysine transport(GO:0015819) |
0.9 | 3.5 | GO:0032901 | positive regulation of neurotrophin production(GO:0032901) |
0.8 | 4.8 | GO:0051461 | regulation of corticotropin secretion(GO:0051459) positive regulation of corticotropin secretion(GO:0051461) |
0.5 | 3.7 | GO:1990118 | sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118) |
0.5 | 3.2 | GO:0032483 | regulation of Rab protein signal transduction(GO:0032483) |
0.5 | 1.5 | GO:2000564 | regulation of MyD88-dependent toll-like receptor signaling pathway(GO:0034124) CD8-positive, alpha-beta T cell proliferation(GO:0035740) negative regulation of regulatory T cell differentiation(GO:0045590) regulation of CD8-positive, alpha-beta T cell proliferation(GO:2000564) |
0.5 | 2.5 | GO:1903553 | positive regulation of extracellular exosome assembly(GO:1903553) |
0.4 | 1.8 | GO:0035026 | leading edge cell differentiation(GO:0035026) |
0.4 | 2.9 | GO:0071699 | olfactory placode formation(GO:0030910) olfactory placode development(GO:0071698) olfactory placode morphogenesis(GO:0071699) |
0.3 | 0.9 | GO:0044339 | canonical Wnt signaling pathway involved in osteoblast differentiation(GO:0044339) |
0.3 | 6.1 | GO:0006883 | cellular sodium ion homeostasis(GO:0006883) |
0.3 | 2.4 | GO:0016114 | terpenoid biosynthetic process(GO:0016114) |
0.3 | 8.8 | GO:0048791 | calcium ion-regulated exocytosis of neurotransmitter(GO:0048791) |
0.3 | 1.1 | GO:0071692 | protein localization to extracellular region(GO:0071692) maintenance of protein location in extracellular region(GO:0071694) |
0.3 | 1.0 | GO:0007412 | axon target recognition(GO:0007412) |
0.3 | 3.1 | GO:0045217 | cell-cell junction maintenance(GO:0045217) |
0.2 | 4.5 | GO:0016082 | synaptic vesicle priming(GO:0016082) |
0.2 | 1.4 | GO:0060385 | axonogenesis involved in innervation(GO:0060385) |
0.2 | 7.6 | GO:0032728 | positive regulation of interferon-beta production(GO:0032728) |
0.2 | 1.7 | GO:0000395 | mRNA 5'-splice site recognition(GO:0000395) |
0.2 | 0.4 | GO:0008065 | establishment of blood-nerve barrier(GO:0008065) |
0.2 | 0.6 | GO:1902498 | regulation of protein autoubiquitination(GO:1902498) |
0.2 | 1.9 | GO:1903861 | regulation of dendrite extension(GO:1903859) positive regulation of dendrite extension(GO:1903861) |
0.2 | 0.5 | GO:0003104 | positive regulation of glomerular filtration(GO:0003104) cell communication by chemical coupling(GO:0010643) |
0.2 | 3.4 | GO:0034142 | toll-like receptor 4 signaling pathway(GO:0034142) |
0.2 | 2.0 | GO:0046643 | regulation of gamma-delta T cell differentiation(GO:0045586) regulation of gamma-delta T cell activation(GO:0046643) |
0.1 | 0.7 | GO:0010668 | ectodermal cell differentiation(GO:0010668) |
0.1 | 5.0 | GO:0050873 | brown fat cell differentiation(GO:0050873) |
0.1 | 2.3 | GO:0045742 | positive regulation of epidermal growth factor receptor signaling pathway(GO:0045742) |
0.1 | 1.8 | GO:0032287 | peripheral nervous system myelin maintenance(GO:0032287) |
0.1 | 5.1 | GO:0048678 | response to axon injury(GO:0048678) |
0.1 | 0.2 | GO:0045657 | positive regulation of monocyte differentiation(GO:0045657) |
0.1 | 0.4 | GO:0097011 | cellular response to granulocyte macrophage colony-stimulating factor stimulus(GO:0097011) response to granulocyte macrophage colony-stimulating factor(GO:0097012) |
0.1 | 2.5 | GO:0001937 | negative regulation of endothelial cell proliferation(GO:0001937) |
0.1 | 2.6 | GO:0043001 | Golgi to plasma membrane protein transport(GO:0043001) |
0.1 | 0.5 | GO:0035520 | monoubiquitinated protein deubiquitination(GO:0035520) |
0.0 | 0.2 | GO:0008655 | pyrimidine-containing compound salvage(GO:0008655) pyrimidine nucleoside salvage(GO:0043097) |
0.0 | 1.2 | GO:0034198 | cellular response to amino acid starvation(GO:0034198) |
0.0 | 0.5 | GO:0006268 | DNA unwinding involved in DNA replication(GO:0006268) |
0.0 | 0.6 | GO:0046548 | retinal rod cell development(GO:0046548) |
0.0 | 0.1 | GO:0006438 | valyl-tRNA aminoacylation(GO:0006438) |
0.0 | 0.5 | GO:0045653 | negative regulation of megakaryocyte differentiation(GO:0045653) |
0.0 | 1.2 | GO:0051591 | response to cAMP(GO:0051591) |
0.0 | 4.8 | GO:0048839 | inner ear development(GO:0048839) |
0.0 | 0.8 | GO:0042168 | heme metabolic process(GO:0042168) |
0.0 | 0.4 | GO:0048488 | synaptic vesicle endocytosis(GO:0048488) |
0.0 | 2.0 | GO:0016579 | protein deubiquitination(GO:0016579) |
0.0 | 0.2 | GO:0090557 | establishment of endothelial intestinal barrier(GO:0090557) |
0.0 | 0.5 | GO:0031146 | SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146) |
0.0 | 0.2 | GO:0051044 | positive regulation of membrane protein ectodomain proteolysis(GO:0051044) |
0.0 | 0.0 | GO:0072015 | glomerular visceral epithelial cell development(GO:0072015) glomerular epithelial cell development(GO:0072310) |
0.0 | 0.2 | GO:0048266 | behavioral response to pain(GO:0048266) |
Gene overrepresentation in cellular_component category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
1.2 | 4.8 | GO:0017071 | intracellular cyclic nucleotide activated cation channel complex(GO:0017071) |
0.6 | 2.5 | GO:0031092 | platelet alpha granule membrane(GO:0031092) |
0.6 | 3.4 | GO:0046696 | lipopolysaccharide receptor complex(GO:0046696) |
0.5 | 2.8 | GO:0061689 | tricellular tight junction(GO:0061689) |
0.4 | 1.8 | GO:0070022 | transforming growth factor beta receptor homodimeric complex(GO:0070022) |
0.2 | 1.2 | GO:1990131 | EGO complex(GO:0034448) Gtr1-Gtr2 GTPase complex(GO:1990131) |
0.2 | 1.8 | GO:0035749 | myelin sheath adaxonal region(GO:0035749) |
0.2 | 7.3 | GO:0005790 | smooth endoplasmic reticulum(GO:0005790) |
0.2 | 1.7 | GO:0000243 | commitment complex(GO:0000243) |
0.1 | 10.1 | GO:0005604 | basement membrane(GO:0005604) |
0.1 | 1.1 | GO:0001527 | microfibril(GO:0001527) |
0.1 | 2.9 | GO:0043034 | costamere(GO:0043034) |
0.1 | 2.8 | GO:0030665 | clathrin-coated vesicle membrane(GO:0030665) |
0.1 | 5.7 | GO:0042734 | presynaptic membrane(GO:0042734) |
0.1 | 0.5 | GO:0005916 | fascia adherens(GO:0005916) |
0.1 | 3.2 | GO:0030667 | secretory granule membrane(GO:0030667) |
0.1 | 3.3 | GO:0005913 | cell-cell adherens junction(GO:0005913) |
0.1 | 3.5 | GO:0005776 | autophagosome(GO:0005776) |
0.0 | 0.5 | GO:0042555 | MCM complex(GO:0042555) |
0.0 | 4.1 | GO:0031225 | anchored component of membrane(GO:0031225) |
0.0 | 3.7 | GO:0055037 | recycling endosome(GO:0055037) |
0.0 | 8.5 | GO:0098793 | presynapse(GO:0098793) |
0.0 | 5.3 | GO:0044798 | nuclear transcription factor complex(GO:0044798) |
0.0 | 1.6 | GO:0005581 | collagen trimer(GO:0005581) |
0.0 | 0.6 | GO:0016581 | NuRD complex(GO:0016581) CHD-type complex(GO:0090545) |
0.0 | 4.9 | GO:0043235 | receptor complex(GO:0043235) |
0.0 | 0.2 | GO:0034706 | voltage-gated sodium channel complex(GO:0001518) sodium channel complex(GO:0034706) |
0.0 | 2.4 | GO:0005777 | peroxisome(GO:0005777) microbody(GO:0042579) |
0.0 | 0.2 | GO:0030877 | beta-catenin destruction complex(GO:0030877) |
0.0 | 7.1 | GO:0005887 | integral component of plasma membrane(GO:0005887) |
Gene overrepresentation in molecular_function category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
1.9 | 5.8 | GO:0004966 | galanin receptor activity(GO:0004966) |
1.5 | 7.3 | GO:0086008 | voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization(GO:0086008) |
1.0 | 4.8 | GO:0005052 | peroxisome matrix targeting signal-1 binding(GO:0005052) |
0.9 | 2.6 | GO:0019002 | GMP binding(GO:0019002) |
0.6 | 4.5 | GO:0015189 | L-ornithine transmembrane transporter activity(GO:0000064) arginine transmembrane transporter activity(GO:0015181) L-lysine transmembrane transporter activity(GO:0015189) |
0.6 | 2.4 | GO:0004337 | geranyltranstransferase activity(GO:0004337) |
0.5 | 2.5 | GO:0070053 | thrombospondin receptor activity(GO:0070053) |
0.5 | 3.7 | GO:0005451 | monovalent cation:proton antiporter activity(GO:0005451) sodium:proton antiporter activity(GO:0015385) potassium:proton antiporter activity(GO:0015386) |
0.4 | 3.5 | GO:0048403 | brain-derived neurotrophic factor binding(GO:0048403) |
0.3 | 4.1 | GO:0008191 | metalloendopeptidase inhibitor activity(GO:0008191) |
0.3 | 11.4 | GO:0005544 | calcium-dependent phospholipid binding(GO:0005544) |
0.3 | 1.0 | GO:0031694 | alpha-2A adrenergic receptor binding(GO:0031694) |
0.2 | 2.8 | GO:0030228 | lipoprotein particle receptor activity(GO:0030228) |
0.2 | 3.4 | GO:0001530 | lipopolysaccharide binding(GO:0001530) |
0.2 | 2.3 | GO:0030296 | protein tyrosine kinase activator activity(GO:0030296) |
0.2 | 1.4 | GO:0035615 | clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748) |
0.1 | 2.5 | GO:0035198 | miRNA binding(GO:0035198) |
0.1 | 0.5 | GO:0071253 | connexin binding(GO:0071253) |
0.1 | 6.1 | GO:0004879 | RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879) transcription factor activity, direct ligand regulated sequence-specific DNA binding(GO:0098531) |
0.1 | 1.8 | GO:0004385 | guanylate kinase activity(GO:0004385) |
0.1 | 3.2 | GO:0017112 | Rab guanyl-nucleotide exchange factor activity(GO:0017112) |
0.1 | 6.0 | GO:0000979 | RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979) |
0.1 | 4.6 | GO:0005518 | collagen binding(GO:0005518) |
0.0 | 1.7 | GO:0036002 | pre-mRNA binding(GO:0036002) |
0.0 | 0.2 | GO:0004849 | uridine kinase activity(GO:0004849) |
0.0 | 5.6 | GO:0001078 | transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078) |
0.0 | 1.8 | GO:0001046 | core promoter sequence-specific DNA binding(GO:0001046) |
0.0 | 2.4 | GO:0020037 | heme binding(GO:0020037) |
0.0 | 1.4 | GO:0001540 | beta-amyloid binding(GO:0001540) |
0.0 | 1.8 | GO:0048306 | calcium-dependent protein binding(GO:0048306) |
0.0 | 0.5 | GO:0030955 | potassium ion binding(GO:0030955) |
0.0 | 3.3 | GO:0008013 | beta-catenin binding(GO:0008013) |
0.0 | 0.1 | GO:0004832 | valine-tRNA ligase activity(GO:0004832) |
0.0 | 2.1 | GO:0004252 | serine-type endopeptidase activity(GO:0004252) |
0.0 | 0.4 | GO:0017166 | vinculin binding(GO:0017166) |
0.0 | 3.8 | GO:0052689 | carboxylic ester hydrolase activity(GO:0052689) |
0.0 | 2.5 | GO:0101005 | thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005) |
0.0 | 0.2 | GO:0031402 | sodium ion binding(GO:0031402) |
0.0 | 4.5 | GO:0003924 | GTPase activity(GO:0003924) |
0.0 | 0.2 | GO:0019855 | calcium channel inhibitor activity(GO:0019855) |
0.0 | 8.9 | GO:0005509 | calcium ion binding(GO:0005509) |
0.0 | 0.5 | GO:0030276 | clathrin binding(GO:0030276) |
0.0 | 0.5 | GO:0004003 | ATP-dependent DNA helicase activity(GO:0004003) |