Motif ID: Sin3a

Z-value: 1.014


Transcription factors associated with Sin3a:

Gene SymbolEntrez IDGene Name
Sin3a ENSMUSG00000042557.8 Sin3a

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Sin3amm10_v2_chr9_+_57076343_570763870.421.4e-01Click!


Activity profile for motif Sin3a.

activity profile for motif Sin3a


Sorted Z-values histogram for motif Sin3a

Sorted Z-values for motif Sin3a



Network of associatons between targets according to the STRING database.



First level regulatory network of Sin3a

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr1_+_39193731 2.079 ENSMUST00000173050.1
Npas2
neuronal PAS domain protein 2
chr7_+_36698002 1.751 ENSMUST00000021641.6
Tshz3
teashirt zinc finger family member 3
chr15_-_66286224 1.095 ENSMUST00000070256.7
Kcnq3
potassium voltage-gated channel, subfamily Q, member 3
chr18_-_72351009 1.053 ENSMUST00000073379.5
Dcc
deleted in colorectal carcinoma
chr18_-_72351029 1.006 ENSMUST00000114943.3
Dcc
deleted in colorectal carcinoma
chr6_-_99521153 0.999 ENSMUST00000177227.1
Foxp1
forkhead box P1
chr15_+_40655020 0.964 ENSMUST00000053467.4
Zfpm2
zinc finger protein, multitype 2
chrX_-_147554050 0.961 ENSMUST00000112819.2
ENSMUST00000136789.1
Lrch2

leucine-rich repeats and calponin homology (CH) domain containing 2

chr16_+_81200697 0.924 ENSMUST00000067602.3
ENSMUST00000037785.7
Ncam2

neural cell adhesion molecule 2

chr6_-_39206782 0.879 ENSMUST00000002305.8
Jhdm1d
jumonji C domain-containing histone demethylase 1 homolog D (S. cerevisiae)
chr14_-_98169542 0.878 ENSMUST00000069334.7
ENSMUST00000071533.6
Dach1

dachshund 1 (Drosophila)

chr12_-_64965496 0.872 ENSMUST00000021331.7
Klhl28
kelch-like 28
chr11_-_87359011 0.865 ENSMUST00000055438.4
Ppm1e
protein phosphatase 1E (PP2C domain containing)
chr12_+_64965742 0.861 ENSMUST00000066296.7
Fam179b
family with sequence similarity 179, member B
chr14_-_49525840 0.853 ENSMUST00000138884.1
ENSMUST00000074368.4
ENSMUST00000123534.1
Slc35f4


solute carrier family 35, member F4


chr16_-_52452465 0.840 ENSMUST00000170035.1
ENSMUST00000164728.1
Alcam

activated leukocyte cell adhesion molecule

chr1_-_10232670 0.839 ENSMUST00000088615.4
ENSMUST00000131556.1
Arfgef1

ADP-ribosylation factor guanine nucleotide-exchange factor 1(brefeldin A-inhibited)

chr9_+_75071579 0.816 ENSMUST00000136731.1
Myo5a
myosin VA
chr4_+_125490688 0.813 ENSMUST00000030676.7
Grik3
glutamate receptor, ionotropic, kainate 3
chr1_-_106714217 0.803 ENSMUST00000112751.1
Bcl2
B cell leukemia/lymphoma 2

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 361 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 2.4 GO:0061470 T follicular helper cell differentiation(GO:0061470)
0.7 2.2 GO:0050975 sensory perception of touch(GO:0050975)
0.4 2.2 GO:0021965 spinal cord ventral commissure morphogenesis(GO:0021965)
0.3 2.1 GO:0051775 response to redox state(GO:0051775)
0.3 2.0 GO:0006477 protein sulfation(GO:0006477)
0.4 1.6 GO:0051643 endoplasmic reticulum localization(GO:0051643)
0.2 1.6 GO:0048386 positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
0.1 1.3 GO:0060081 membrane hyperpolarization(GO:0060081)
0.1 1.3 GO:0008045 motor neuron axon guidance(GO:0008045)
0.2 1.2 GO:2000301 negative regulation of synaptic vesicle exocytosis(GO:2000301)
0.1 1.2 GO:0048681 negative regulation of axon regeneration(GO:0048681)
0.1 1.2 GO:0021785 branchiomotor neuron axon guidance(GO:0021785)
0.1 1.2 GO:1990403 embryonic brain development(GO:1990403)
0.3 1.1 GO:2000795 negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.2 1.1 GO:0030643 cellular phosphate ion homeostasis(GO:0030643) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.1 1.1 GO:0097118 neuroligin clustering involved in postsynaptic membrane assembly(GO:0097118)
0.1 1.1 GO:0050882 voluntary musculoskeletal movement(GO:0050882)
0.3 1.0 GO:0032240 negative regulation of nucleobase-containing compound transport(GO:0032240) negative regulation of RNA export from nucleus(GO:0046832)
0.3 1.0 GO:1902528 regulation of protein linear polyubiquitination(GO:1902528) positive regulation of protein linear polyubiquitination(GO:1902530)
0.3 1.0 GO:0003221 right ventricular cardiac muscle tissue morphogenesis(GO:0003221)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 132 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 2.6 GO:0045211 postsynaptic membrane(GO:0045211)
0.1 2.4 GO:0043194 axon initial segment(GO:0043194)
0.0 2.4 GO:0098562 cytoplasmic side of membrane(GO:0098562)
0.2 2.1 GO:0032584 growth cone membrane(GO:0032584)
0.1 2.1 GO:0032809 neuronal cell body membrane(GO:0032809)
0.1 1.8 GO:0097470 ribbon synapse(GO:0097470)
0.5 1.6 GO:0042642 actomyosin, myosin complex part(GO:0042642)
0.1 1.3 GO:0030132 clathrin coat of coated pit(GO:0030132)
0.2 1.2 GO:0030289 protein phosphatase 4 complex(GO:0030289)
0.1 1.2 GO:0042101 T cell receptor complex(GO:0042101)
0.0 1.2 GO:0035869 ciliary transition zone(GO:0035869)
0.2 1.1 GO:0044615 nuclear pore nuclear basket(GO:0044615)
0.0 1.1 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.2 0.9 GO:0090537 CERF complex(GO:0090537)
0.1 0.9 GO:0005955 calcineurin complex(GO:0005955)
0.0 0.9 GO:0016592 mediator complex(GO:0016592)
0.0 0.9 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 0.9 GO:0005814 centriole(GO:0005814)
0.1 0.8 GO:0034750 Scrib-APC-beta-catenin complex(GO:0034750)
0.1 0.8 GO:0016589 NURF complex(GO:0016589)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 194 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 3.0 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.4 2.2 GO:0005042 netrin receptor activity(GO:0005042)
0.3 2.1 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.1 2.1 GO:0051879 Hsp90 protein binding(GO:0051879)
0.3 1.8 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.0 1.7 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.1 1.6 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.0 1.6 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.2 1.5 GO:0002151 G-quadruplex RNA binding(GO:0002151)
0.1 1.5 GO:0043008 ATP-dependent protein binding(GO:0043008)
0.1 1.5 GO:0070064 proline-rich region binding(GO:0070064)
0.0 1.5 GO:0051287 NAD binding(GO:0051287)
0.0 1.4 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.1 1.2 GO:0008187 poly-pyrimidine tract binding(GO:0008187)
0.2 1.1 GO:0015198 oligopeptide transporter activity(GO:0015198)
0.1 1.1 GO:0046790 virion binding(GO:0046790)
0.3 1.0 GO:0001075 transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
0.2 1.0 GO:0070840 dynein complex binding(GO:0070840)
0.1 1.0 GO:0001618 virus receptor activity(GO:0001618)
0.0 1.0 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)