Motif ID: Six4

Z-value: 0.482


Transcription factors associated with Six4:

Gene SymbolEntrez IDGene Name
Six4 ENSMUSG00000034460.8 Six4

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Six4mm10_v2_chr12_-_73113407_731134560.039.2e-01Click!


Activity profile for motif Six4.

activity profile for motif Six4


Sorted Z-values histogram for motif Six4

Sorted Z-values for motif Six4



Network of associatons between targets according to the STRING database.



First level regulatory network of Six4

PNG image of the network

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Top targets:


Showing 1 to 20 of 59 entries
PromoterScoreRefseqGene SymbolGene Name
chr15_-_66831625 1.136 ENSMUST00000164163.1
 Sla
src-like adaptor
chr13_+_13590402 0.853 ENSMUST00000110559.1
 Lyst
lysosomal trafficking regulator
chr6_+_149130170 0.726 ENSMUST00000087348.3
 Gm10203
predicted gene 10203
chr13_-_76385028 0.674 ENSMUST00000099365.1
 Gm10760
predicted gene 10760
chr15_+_92051153 0.641 ENSMUST00000169825.1
 Cntn1
contactin 1
chr12_-_41485751 0.620 ENSMUST00000043884.4
 Lrrn3
leucine rich repeat protein 3, neuronal
chr7_+_38183787 0.606 ENSMUST00000067854.8
ENSMUST00000177983.1
 1600014C10Rik

RIKEN cDNA 1600014C10 gene

chr17_-_48409729 0.564 ENSMUST00000160319.1
ENSMUST00000159535.1
ENSMUST00000078800.6
ENSMUST00000046719.7
ENSMUST00000162460.1
 Nfya




nuclear transcription factor-Y alpha




chr7_+_29309429 0.555 ENSMUST00000137848.1
 Dpf1
D4, zinc and double PHD fingers family 1
chr2_-_103797617 0.543 ENSMUST00000028607.6
 Caprin1
cell cycle associated protein 1
chr15_+_65787023 0.468 ENSMUST00000015146.9
ENSMUST00000173858.1
ENSMUST00000172756.1
ENSMUST00000174856.1
 Efr3a



EFR3 homolog A (S. cerevisiae)



chr7_+_29307924 0.441 ENSMUST00000108230.1
ENSMUST00000065181.5
 Dpf1

D4, zinc and double PHD fingers family 1

chr1_-_78968079 0.431 ENSMUST00000049117.5
 Gm5830
predicted pseudogene 5830
chr3_+_40950631 0.423 ENSMUST00000048490.6
 Larp1b
La ribonucleoprotein domain family, member 1B
chr6_+_50110186 0.415 ENSMUST00000166318.1
ENSMUST00000036236.8
ENSMUST00000036225.8
 Mpp6


membrane protein, palmitoylated 6 (MAGUK p55 subfamily member 6)


chr7_-_143460989 0.412 ENSMUST00000167912.1
ENSMUST00000037287.6
 Cdkn1c

cyclin-dependent kinase inhibitor 1C (P57)

chr13_+_73626886 0.411 ENSMUST00000022104.7
 Tert
telomerase reverse transcriptase
chr7_-_132317198 0.387 ENSMUST00000080215.5
 Chst15
carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15
chr13_+_54071815 0.363 ENSMUST00000021930.8
 Sfxn1
sideroflexin 1
chr12_+_75818294 0.346 ENSMUST00000143031.1
ENSMUST00000044217.9
ENSMUST00000150317.1
 Syne2


spectrin repeat containing, nuclear envelope 2



Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 13 of 13 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.3 0.9 GO:0033364 endosome to lysosome transport via multivesicular body sorting pathway(GO:0032510) mast cell secretory granule organization(GO:0033364)
0.0 0.6 GO:2000036 regulation of stem cell population maintenance(GO:2000036)
0.0 0.5 GO:0061003 positive regulation of dendritic spine morphogenesis(GO:0061003)
0.1 0.4 GO:1900369 negative regulation of RNA interference(GO:1900369) regulation of histone demethylase activity (H3-K4 specific)(GO:1904173)
0.0 0.4 GO:0060065 uterus development(GO:0060065)
0.1 0.3 GO:0031022 nuclear migration along microfilament(GO:0031022)
0.0 0.3 GO:0043508 negative regulation of JUN kinase activity(GO:0043508)
0.0 0.3 GO:0000920 cell separation after cytokinesis(GO:0000920)
0.0 0.3 GO:0051457 maintenance of protein location in nucleus(GO:0051457)
0.1 0.2 GO:0006682 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.0 0.1 GO:0031509 telomeric heterochromatin assembly(GO:0031509) negative regulation of chromosome condensation(GO:1902340)
0.0 0.1 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.0 0.0 GO:0060743 epithelial cell maturation involved in prostate gland development(GO:0060743)

Gene overrepresentation in cellular_component category:

Showing 1 to 8 of 8 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 1.0 GO:0071565 nBAF complex(GO:0071565)
0.1 0.6 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.0 0.6 GO:0030131 clathrin adaptor complex(GO:0030131)
0.1 0.5 GO:0001533 cornified envelope(GO:0001533)
0.0 0.5 GO:0005697 telomerase holoenzyme complex(GO:0005697)
0.0 0.3 GO:0034993 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0 0.3 GO:0005669 transcription factor TFIID complex(GO:0005669)
0.0 0.1 GO:0001740 Barr body(GO:0001740)

Gene overrepresentation in molecular_function category:

Showing 1 to 6 of 6 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 0.6 GO:0001221 transcription cofactor binding(GO:0001221)
0.1 0.4 GO:0050656 3'-phosphoadenosine 5'-phosphosulfate binding(GO:0050656)
0.0 0.4 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.0 0.4 GO:0070034 telomerase RNA binding(GO:0070034)
0.0 0.4 GO:0004385 guanylate kinase activity(GO:0004385)
0.0 0.2 GO:0001733 galactosylceramide sulfotransferase activity(GO:0001733)