Motif ID: Six6
Z-value: 0.856
Transcription factors associated with Six6:
Gene Symbol | Entrez ID | Gene Name |
---|---|---|
Six6 | ENSMUSG00000021099.5 | Six6 |
Activity-expression correlation:
Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
---|---|---|---|---|
Six6 | mm10_v2_chr12_+_72939724_72939758 | 0.17 | 5.6e-01 | Click! |
Top targets:
Gene overrepresentation in biological_process category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.8 | 3.8 | GO:0034441 | plasma lipoprotein particle oxidation(GO:0034441) |
0.4 | 1.5 | GO:0070318 | positive regulation of G0 to G1 transition(GO:0070318) |
0.3 | 2.8 | GO:0051923 | sulfation(GO:0051923) |
0.2 | 1.0 | GO:0097393 | post-embryonic appendage morphogenesis(GO:0035120) post-embryonic limb morphogenesis(GO:0035127) post-embryonic forelimb morphogenesis(GO:0035128) telomeric repeat-containing RNA transcription(GO:0097393) telomeric repeat-containing RNA transcription from RNA pol II promoter(GO:0097394) regulation of telomeric RNA transcription from RNA pol II promoter(GO:1901580) negative regulation of telomeric RNA transcription from RNA pol II promoter(GO:1901581) positive regulation of telomeric RNA transcription from RNA pol II promoter(GO:1901582) |
0.2 | 1.2 | GO:0007386 | compartment pattern specification(GO:0007386) |
0.2 | 1.0 | GO:0007089 | traversing start control point of mitotic cell cycle(GO:0007089) |
0.2 | 0.6 | GO:2000338 | positive regulation of interleukin-23 production(GO:0032747) chemokine (C-X-C motif) ligand 1 production(GO:0072566) regulation of chemokine (C-X-C motif) ligand 1 production(GO:2000338) |
0.2 | 0.7 | GO:0048539 | bone marrow development(GO:0048539) |
0.2 | 0.8 | GO:0070236 | negative regulation of activation-induced cell death of T cells(GO:0070236) |
0.2 | 0.7 | GO:0006776 | vitamin A metabolic process(GO:0006776) |
0.2 | 0.8 | GO:0051661 | maintenance of centrosome location(GO:0051661) |
0.1 | 0.7 | GO:0060414 | aorta smooth muscle tissue morphogenesis(GO:0060414) |
0.1 | 1.0 | GO:0071474 | cellular hyperosmotic response(GO:0071474) |
0.1 | 1.3 | GO:0030388 | fructose 1,6-bisphosphate metabolic process(GO:0030388) |
0.1 | 0.4 | GO:0048496 | maintenance of organ identity(GO:0048496) |
0.1 | 0.7 | GO:2000002 | negative regulation of DNA damage checkpoint(GO:2000002) |
0.1 | 0.3 | GO:0002314 | germinal center B cell differentiation(GO:0002314) |
0.1 | 0.8 | GO:0042760 | very long-chain fatty acid catabolic process(GO:0042760) |
0.1 | 0.8 | GO:0000712 | resolution of meiotic recombination intermediates(GO:0000712) |
0.1 | 0.3 | GO:0097428 | protein maturation by iron-sulfur cluster transfer(GO:0097428) |
0.1 | 0.3 | GO:0060032 | notochord regression(GO:0060032) |
0.1 | 0.5 | GO:0006686 | sphingomyelin biosynthetic process(GO:0006686) |
0.1 | 0.3 | GO:0072488 | ammonium transmembrane transport(GO:0072488) |
0.1 | 0.8 | GO:1901673 | regulation of mitotic spindle assembly(GO:1901673) |
0.1 | 0.5 | GO:0015074 | DNA integration(GO:0015074) |
0.1 | 0.4 | GO:0071294 | cellular response to zinc ion(GO:0071294) |
0.1 | 1.1 | GO:0003351 | epithelial cilium movement(GO:0003351) |
0.1 | 0.2 | GO:0044849 | estrous cycle(GO:0044849) |
0.0 | 0.4 | GO:0097460 | positive regulation of oligodendrocyte progenitor proliferation(GO:0070447) ferrous iron import into cell(GO:0097460) |
0.0 | 0.2 | GO:0046208 | spermine catabolic process(GO:0046208) |
0.0 | 0.3 | GO:1903352 | ornithine transport(GO:0015822) L-ornithine transmembrane transport(GO:1903352) |
0.0 | 0.4 | GO:2001214 | positive regulation of vasculogenesis(GO:2001214) |
0.0 | 0.7 | GO:0045954 | positive regulation of natural killer cell mediated cytotoxicity(GO:0045954) |
0.0 | 0.2 | GO:0030647 | polyketide metabolic process(GO:0030638) aminoglycoside antibiotic metabolic process(GO:0030647) daunorubicin metabolic process(GO:0044597) doxorubicin metabolic process(GO:0044598) |
0.0 | 0.9 | GO:0034315 | regulation of Arp2/3 complex-mediated actin nucleation(GO:0034315) |
0.0 | 0.2 | GO:0043461 | proton-transporting ATP synthase complex assembly(GO:0043461) proton-transporting ATP synthase complex biogenesis(GO:0070272) |
0.0 | 0.1 | GO:0031581 | hemidesmosome assembly(GO:0031581) |
0.0 | 0.4 | GO:0006268 | DNA unwinding involved in DNA replication(GO:0006268) |
0.0 | 0.7 | GO:0006828 | manganese ion transport(GO:0006828) |
0.0 | 0.1 | GO:0060392 | negative regulation of SMAD protein import into nucleus(GO:0060392) |
0.0 | 0.3 | GO:0006729 | tetrahydrobiopterin biosynthetic process(GO:0006729) tetrahydrobiopterin metabolic process(GO:0046146) |
0.0 | 0.3 | GO:0050957 | equilibrioception(GO:0050957) |
0.0 | 0.3 | GO:0016127 | cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127) |
0.0 | 0.5 | GO:0045792 | negative regulation of cell size(GO:0045792) |
0.0 | 0.2 | GO:0010748 | negative regulation of plasma membrane long-chain fatty acid transport(GO:0010748) |
0.0 | 0.1 | GO:0031022 | nuclear migration along microfilament(GO:0031022) |
0.0 | 0.5 | GO:0033194 | response to hydroperoxide(GO:0033194) |
0.0 | 0.1 | GO:0019614 | catechol-containing compound catabolic process(GO:0019614) catecholamine catabolic process(GO:0042424) |
0.0 | 0.5 | GO:0006958 | complement activation, classical pathway(GO:0006958) |
0.0 | 2.5 | GO:0009566 | fertilization(GO:0009566) |
0.0 | 0.1 | GO:0001580 | detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580) |
0.0 | 0.2 | GO:0045974 | miRNA mediated inhibition of translation(GO:0035278) negative regulation of translation, ncRNA-mediated(GO:0040033) regulation of translation, ncRNA-mediated(GO:0045974) |
0.0 | 0.2 | GO:0030150 | protein import into mitochondrial matrix(GO:0030150) |
0.0 | 0.3 | GO:0071624 | positive regulation of granulocyte chemotaxis(GO:0071624) positive regulation of neutrophil chemotaxis(GO:0090023) |
0.0 | 0.2 | GO:0043928 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928) |
0.0 | 0.1 | GO:0032790 | ribosome disassembly(GO:0032790) |
0.0 | 0.6 | GO:0007026 | negative regulation of microtubule depolymerization(GO:0007026) |
0.0 | 0.4 | GO:0001706 | endoderm formation(GO:0001706) |
0.0 | 0.2 | GO:0009048 | dosage compensation by inactivation of X chromosome(GO:0009048) |
0.0 | 0.3 | GO:0048266 | behavioral response to pain(GO:0048266) |
0.0 | 0.1 | GO:0071372 | cellular response to follicle-stimulating hormone stimulus(GO:0071372) |
Gene overrepresentation in cellular_component category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.3 | 3.8 | GO:0034362 | low-density lipoprotein particle(GO:0034362) |
0.2 | 1.0 | GO:1990421 | subtelomeric heterochromatin(GO:1990421) nuclear subtelomeric heterochromatin(GO:1990707) |
0.2 | 0.8 | GO:0036449 | microtubule minus-end(GO:0036449) |
0.1 | 0.4 | GO:0097543 | ciliary inversin compartment(GO:0097543) |
0.1 | 0.5 | GO:0019815 | B cell receptor complex(GO:0019815) |
0.1 | 0.8 | GO:0000815 | ESCRT III complex(GO:0000815) |
0.1 | 0.2 | GO:0032311 | angiogenin-PRI complex(GO:0032311) |
0.1 | 0.7 | GO:0005688 | U6 snRNP(GO:0005688) |
0.1 | 0.7 | GO:0098643 | fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643) |
0.0 | 0.4 | GO:0031232 | extrinsic component of external side of plasma membrane(GO:0031232) dense body(GO:0097433) |
0.0 | 2.2 | GO:0005801 | cis-Golgi network(GO:0005801) |
0.0 | 0.2 | GO:0045098 | type III intermediate filament(GO:0045098) |
0.0 | 0.4 | GO:0033179 | proton-transporting V-type ATPase, V0 domain(GO:0033179) |
0.0 | 0.2 | GO:0035068 | micro-ribonucleoprotein complex(GO:0035068) |
0.0 | 0.9 | GO:0032588 | trans-Golgi network membrane(GO:0032588) |
0.0 | 0.4 | GO:0042555 | MCM complex(GO:0042555) |
0.0 | 0.3 | GO:0097542 | ciliary tip(GO:0097542) |
0.0 | 0.1 | GO:0034993 | microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993) |
0.0 | 0.1 | GO:0030915 | Smc5-Smc6 complex(GO:0030915) |
0.0 | 0.2 | GO:0031080 | nuclear pore outer ring(GO:0031080) |
0.0 | 0.2 | GO:0032593 | insulin-responsive compartment(GO:0032593) |
0.0 | 1.0 | GO:0001669 | acrosomal vesicle(GO:0001669) |
0.0 | 0.1 | GO:0030056 | hemidesmosome(GO:0030056) |
0.0 | 0.2 | GO:0043219 | lateral loop(GO:0043219) |
0.0 | 2.6 | GO:0044306 | neuron projection terminus(GO:0044306) |
0.0 | 0.1 | GO:0048188 | Set1C/COMPASS complex(GO:0048188) |
0.0 | 0.2 | GO:0001741 | XY body(GO:0001741) |
Gene overrepresentation in molecular_function category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.9 | 2.8 | GO:0050656 | 3'-phosphoadenosine 5'-phosphosulfate binding(GO:0050656) |
0.4 | 3.8 | GO:0003847 | 1-alkyl-2-acetylglycerophosphocholine esterase activity(GO:0003847) calcium-independent phospholipase A2 activity(GO:0047499) |
0.4 | 1.2 | GO:0033829 | O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829) |
0.2 | 0.6 | GO:0004127 | cytidylate kinase activity(GO:0004127) |
0.2 | 1.3 | GO:0004332 | fructose-bisphosphate aldolase activity(GO:0004332) |
0.1 | 0.7 | GO:0030621 | U4 snRNA binding(GO:0030621) |
0.1 | 0.6 | GO:0070976 | TIR domain binding(GO:0070976) |
0.1 | 1.0 | GO:0015616 | DNA translocase activity(GO:0015616) |
0.1 | 0.4 | GO:0030171 | voltage-gated proton channel activity(GO:0030171) |
0.1 | 0.5 | GO:0033188 | sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493) |
0.1 | 0.7 | GO:0019841 | retinol binding(GO:0019841) |
0.1 | 0.3 | GO:0035673 | oligopeptide transmembrane transporter activity(GO:0035673) |
0.1 | 0.2 | GO:0046592 | polyamine oxidase activity(GO:0046592) spermine:oxygen oxidoreductase (spermidine-forming) activity(GO:0052901) |
0.1 | 1.5 | GO:0005520 | insulin-like growth factor binding(GO:0005520) |
0.1 | 0.7 | GO:0015279 | store-operated calcium channel activity(GO:0015279) |
0.1 | 0.4 | GO:0015091 | ferric iron transmembrane transporter activity(GO:0015091) trivalent inorganic cation transmembrane transporter activity(GO:0072510) |
0.1 | 0.8 | GO:0016290 | palmitoyl-CoA hydrolase activity(GO:0016290) |
0.1 | 0.3 | GO:0003854 | 3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854) |
0.0 | 0.7 | GO:0048407 | platelet-derived growth factor binding(GO:0048407) |
0.0 | 0.7 | GO:0005035 | tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035) |
0.0 | 0.4 | GO:0008395 | steroid hydroxylase activity(GO:0008395) |
0.0 | 0.3 | GO:0015189 | L-ornithine transmembrane transporter activity(GO:0000064) arginine transmembrane transporter activity(GO:0015181) L-lysine transmembrane transporter activity(GO:0015189) |
0.0 | 0.2 | GO:0031727 | CCR2 chemokine receptor binding(GO:0031727) |
0.0 | 0.2 | GO:0008428 | ribonuclease inhibitor activity(GO:0008428) |
0.0 | 0.1 | GO:0008410 | CoA-transferase activity(GO:0008410) |
0.0 | 0.5 | GO:0034987 | immunoglobulin receptor binding(GO:0034987) |
0.0 | 0.1 | GO:0016206 | catechol O-methyltransferase activity(GO:0016206) |
0.0 | 0.7 | GO:0030676 | Rac guanyl-nucleotide exchange factor activity(GO:0030676) |
0.0 | 0.9 | GO:0070273 | phosphatidylinositol-4-phosphate binding(GO:0070273) |
0.0 | 0.3 | GO:0045236 | CXCR chemokine receptor binding(GO:0045236) |
0.0 | 0.1 | GO:0010698 | acetyltransferase activator activity(GO:0010698) |
0.0 | 0.2 | GO:0004716 | receptor signaling protein tyrosine kinase activity(GO:0004716) |
0.0 | 0.7 | GO:0016655 | oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor(GO:0016655) |
0.0 | 0.3 | GO:0008519 | ammonium transmembrane transporter activity(GO:0008519) |
0.0 | 0.4 | GO:0046961 | proton-transporting ATPase activity, rotational mechanism(GO:0046961) |
0.0 | 0.3 | GO:0051537 | 2 iron, 2 sulfur cluster binding(GO:0051537) |
0.0 | 0.2 | GO:0080025 | phosphatidylinositol-3,5-bisphosphate binding(GO:0080025) |
0.0 | 0.2 | GO:0019215 | intermediate filament binding(GO:0019215) |