Motif ID: Smad2
Z-value: 0.878
Transcription factors associated with Smad2:
| Gene Symbol | Entrez ID | Gene Name |
|---|---|---|
| Smad2 | ENSMUSG00000024563.9 | Smad2 |
Activity-expression correlation:
| Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| Smad2 | mm10_v2_chr18_+_76241892_76242046 | -0.70 | 5.6e-03 | Click! |
Top targets:
Showing 1 to 20 of 66 entries
Gene overrepresentation in biological_process category:
Showing 1 to 20 of 29 entries
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 2.1 | 6.3 | GO:0061537 | glycine secretion(GO:0061536) glycine secretion, neurotransmission(GO:0061537) |
| 0.1 | 3.7 | GO:0035019 | somatic stem cell population maintenance(GO:0035019) |
| 0.2 | 3.4 | GO:0021796 | cerebral cortex regionalization(GO:0021796) |
| 0.0 | 3.2 | GO:0008360 | regulation of cell shape(GO:0008360) |
| 0.9 | 2.8 | GO:0060166 | olfactory pit development(GO:0060166) |
| 0.8 | 2.5 | GO:1903279 | regulation of calcium:sodium antiporter activity(GO:1903279) |
| 0.1 | 2.3 | GO:0032060 | bleb assembly(GO:0032060) |
| 0.0 | 2.0 | GO:0008277 | regulation of G-protein coupled receptor protein signaling pathway(GO:0008277) |
| 0.0 | 1.9 | GO:0016525 | negative regulation of angiogenesis(GO:0016525) |
| 0.3 | 1.7 | GO:1903012 | positive regulation of bone development(GO:1903012) |
| 0.1 | 1.7 | GO:0002495 | antigen processing and presentation of peptide antigen via MHC class II(GO:0002495) |
| 0.0 | 1.7 | GO:0042632 | cholesterol homeostasis(GO:0042632) sterol homeostasis(GO:0055092) |
| 0.1 | 1.6 | GO:0051967 | negative regulation of synaptic transmission, glutamatergic(GO:0051967) |
| 0.0 | 1.6 | GO:0006270 | DNA replication initiation(GO:0006270) |
| 0.3 | 1.1 | GO:0072697 | protein localization to cell cortex(GO:0072697) |
| 0.0 | 1.0 | GO:0097178 | ruffle assembly(GO:0097178) |
| 0.0 | 0.8 | GO:0070206 | protein trimerization(GO:0070206) |
| 0.1 | 0.7 | GO:0016198 | axon choice point recognition(GO:0016198) |
| 0.1 | 0.7 | GO:0032793 | positive regulation of CREB transcription factor activity(GO:0032793) |
| 0.2 | 0.6 | GO:0035621 | ER to Golgi ceramide transport(GO:0035621) ceramide transport(GO:0035627) |
Gene overrepresentation in cellular_component category:
Showing 1 to 14 of 14 entries
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 6.3 | GO:0098793 | presynapse(GO:0098793) |
| 0.4 | 2.5 | GO:0005890 | sodium:potassium-exchanging ATPase complex(GO:0005890) |
| 0.1 | 2.3 | GO:0043218 | compact myelin(GO:0043218) |
| 0.0 | 2.2 | GO:0043197 | dendritic spine(GO:0043197) |
| 0.0 | 2.0 | GO:0042734 | presynaptic membrane(GO:0042734) |
| 0.1 | 1.7 | GO:0032588 | trans-Golgi network membrane(GO:0032588) |
| 0.3 | 1.6 | GO:0032983 | kainate selective glutamate receptor complex(GO:0032983) |
| 0.0 | 1.0 | GO:0030864 | cortical actin cytoskeleton(GO:0030864) |
| 0.0 | 0.8 | GO:0016328 | lateral plasma membrane(GO:0016328) |
| 0.1 | 0.4 | GO:0042585 | germinal vesicle(GO:0042585) |
| 0.1 | 0.3 | GO:0008282 | ATP-sensitive potassium channel complex(GO:0008282) |
| 0.0 | 0.3 | GO:0046581 | intercellular canaliculus(GO:0046581) |
| 0.0 | 0.3 | GO:0005915 | zonula adherens(GO:0005915) |
| 0.0 | 0.2 | GO:0034993 | microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993) |
Gene overrepresentation in molecular_function category:
Showing 1 to 20 of 24 entries
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.0 | 6.3 | GO:0015375 | glycine:sodium symporter activity(GO:0015375) |
| 0.0 | 3.7 | GO:0003714 | transcription corepressor activity(GO:0003714) |
| 0.1 | 2.8 | GO:0071837 | HMG box domain binding(GO:0071837) |
| 0.3 | 2.5 | GO:0103116 | alpha-D-galactofuranose transporter activity(GO:0103116) steroid hormone binding(GO:1990239) |
| 0.2 | 1.9 | GO:0005041 | low-density lipoprotein receptor activity(GO:0005041) |
| 0.1 | 1.7 | GO:0017128 | phospholipid scramblase activity(GO:0017128) |
| 0.1 | 1.7 | GO:0042287 | MHC protein binding(GO:0042287) |
| 0.0 | 1.7 | GO:0017124 | SH3 domain binding(GO:0017124) |
| 0.3 | 1.6 | GO:0015277 | kainate selective glutamate receptor activity(GO:0015277) |
| 0.1 | 1.6 | GO:0044323 | retinoic acid-responsive element binding(GO:0044323) |
| 0.0 | 1.6 | GO:0016538 | cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538) |
| 0.1 | 1.1 | GO:0032794 | GTPase activating protein binding(GO:0032794) |
| 0.0 | 1.0 | GO:0003785 | actin monomer binding(GO:0003785) |
| 0.1 | 0.7 | GO:0001849 | complement component C1q binding(GO:0001849) |
| 0.1 | 0.7 | GO:0005095 | GTPase inhibitor activity(GO:0005095) |
| 0.1 | 0.7 | GO:0008140 | cAMP response element binding protein binding(GO:0008140) |
| 0.0 | 0.7 | GO:0046875 | ephrin receptor binding(GO:0046875) |
| 0.1 | 0.6 | GO:0097001 | sphingolipid transporter activity(GO:0046624) ceramide binding(GO:0097001) |
| 0.0 | 0.4 | GO:0004435 | phosphatidylinositol phospholipase C activity(GO:0004435) |
| 0.0 | 0.3 | GO:0070097 | delta-catenin binding(GO:0070097) |
