Motif ID: Smad4

Z-value: 0.884


Transcription factors associated with Smad4:

Gene SymbolEntrez IDGene Name
Smad4 ENSMUSG00000024515.7 Smad4

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Smad4mm10_v2_chr18_-_73703739_737038060.185.5e-01Click!


Activity profile for motif Smad4.

activity profile for motif Smad4


Sorted Z-values histogram for motif Smad4

Sorted Z-values for motif Smad4



Network of associatons between targets according to the STRING database.



First level regulatory network of Smad4

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr1_+_153652943 3.133 ENSMUST00000041776.5
Rgs8
regulator of G-protein signaling 8
chr11_-_33147400 2.983 ENSMUST00000020507.7
Fgf18
fibroblast growth factor 18
chr11_-_95514570 2.971 ENSMUST00000058866.7
Nxph3
neurexophilin 3
chr10_-_127534540 2.360 ENSMUST00000095266.2
Nxph4
neurexophilin 4
chr5_+_75574916 1.251 ENSMUST00000144270.1
ENSMUST00000005815.6
Kit

kit oncogene

chr6_-_138422898 1.202 ENSMUST00000161450.1
ENSMUST00000163024.1
ENSMUST00000162185.1
Lmo3


LIM domain only 3


chr19_+_5740885 1.016 ENSMUST00000081496.5
Ltbp3
latent transforming growth factor beta binding protein 3
chr1_+_152399824 0.987 ENSMUST00000044311.8
Colgalt2
collagen beta(1-O)galactosyltransferase 2
chr9_-_45936049 0.972 ENSMUST00000034590.2
Tagln
transgelin
chr7_+_45216671 0.927 ENSMUST00000134420.1
Tead2
TEA domain family member 2
chr11_-_60115226 0.917 ENSMUST00000130746.1
4930412M03Rik
RIKEN cDNA 4930412M03 gene
chr17_+_72918298 0.876 ENSMUST00000024857.6
Lbh
limb-bud and heart
chr7_+_45215753 0.842 ENSMUST00000033060.6
ENSMUST00000155313.1
ENSMUST00000107801.1
Tead2


TEA domain family member 2


chr18_+_57133065 0.836 ENSMUST00000075770.6
Megf10
multiple EGF-like-domains 10
chr17_+_34597852 0.834 ENSMUST00000174496.2
ENSMUST00000015596.3
ENSMUST00000173992.1
Ager


advanced glycosylation end product-specific receptor


chr3_+_127633134 0.792 ENSMUST00000029587.7
Neurog2
neurogenin 2
chr6_+_54040078 0.730 ENSMUST00000127323.2
Chn2
chimerin (chimaerin) 2
chrX_+_41401476 0.711 ENSMUST00000165288.1
Gria3
glutamate receptor, ionotropic, AMPA3 (alpha 3)
chr5_-_24601961 0.701 ENSMUST00000030791.7
Smarcd3
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3
chr10_-_42583628 0.699 ENSMUST00000019938.4
Nr2e1
nuclear receptor subfamily 2, group E, member 1
chr7_-_70360593 0.665 ENSMUST00000032768.7
Nr2f2
nuclear receptor subfamily 2, group F, member 2
chr10_+_75589363 0.652 ENSMUST00000072217.2
Ggt5
gamma-glutamyltransferase 5
chr11_-_5261558 0.650 ENSMUST00000020662.8
Kremen1
kringle containing transmembrane protein 1
chr8_-_109251698 0.641 ENSMUST00000079189.3
4922502B01Rik
RIKEN cDNA 4922502B01 gene
chr4_+_97772734 0.555 ENSMUST00000152023.1
Nfia
nuclear factor I/A
chrX_+_150588223 0.547 ENSMUST00000153221.1
Pfkfb1
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1
chr15_+_39076885 0.543 ENSMUST00000067072.3
Cthrc1
collagen triple helix repeat containing 1
chr7_-_45870928 0.511 ENSMUST00000146672.1
Grin2d
glutamate receptor, ionotropic, NMDA2D (epsilon 4)
chr19_-_23448322 0.494 ENSMUST00000036069.6
Mamdc2
MAM domain containing 2
chr11_-_26591729 0.479 ENSMUST00000109504.1
Vrk2
vaccinia related kinase 2
chr14_+_12189943 0.474 ENSMUST00000119888.1
Ptprg
protein tyrosine phosphatase, receptor type, G
chrX_+_99136119 0.464 ENSMUST00000052839.6
Efnb1
ephrin B1
chr6_+_143285988 0.460 ENSMUST00000160951.1
D6Ertd474e
DNA segment, Chr 6, ERATO Doi 474, expressed
chr2_-_173276144 0.457 ENSMUST00000139306.1
Pmepa1
prostate transmembrane protein, androgen induced 1
chr14_-_54577578 0.448 ENSMUST00000054487.8
Ajuba
ajuba LIM protein
chr10_-_109764840 0.448 ENSMUST00000163071.1
Nav3
neuron navigator 3
chr17_-_28486082 0.439 ENSMUST00000079413.3
Fkbp5
FK506 binding protein 5
chr3_+_102734496 0.415 ENSMUST00000029451.5
Tspan2
tetraspanin 2
chr18_-_52529847 0.397 ENSMUST00000171470.1
Lox
lysyl oxidase
chr12_-_12941827 0.397 ENSMUST00000043396.7
Mycn
v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)
chr4_+_116221633 0.393 ENSMUST00000030464.7
Pik3r3
phosphatidylinositol 3 kinase, regulatory subunit, polypeptide 3 (p55)
chr8_-_34146974 0.386 ENSMUST00000033910.8
Leprotl1
leptin receptor overlapping transcript-like 1
chr17_+_75178797 0.376 ENSMUST00000112516.1
ENSMUST00000135447.1
Ltbp1

latent transforming growth factor beta binding protein 1

chr4_+_116221590 0.364 ENSMUST00000147292.1
Pik3r3
phosphatidylinositol 3 kinase, regulatory subunit, polypeptide 3 (p55)
chr7_-_119895697 0.363 ENSMUST00000059851.6
Dcun1d3
DCN1, defective in cullin neddylation 1, domain containing 3 (S. cerevisiae)
chr12_+_13269111 0.361 ENSMUST00000042953.8
Nbas
neuroblastoma amplified sequence
chr6_-_83775767 0.349 ENSMUST00000014892.6
Tex261
testis expressed gene 261
chr6_-_72958097 0.349 ENSMUST00000114049.1
Tmsb10
thymosin, beta 10
chr7_-_100855403 0.348 ENSMUST00000156855.1
Relt
RELT tumor necrosis factor receptor
chr10_+_80150448 0.347 ENSMUST00000153477.1
Midn
midnolin
chr17_+_75178911 0.345 ENSMUST00000112514.1
Ltbp1
latent transforming growth factor beta binding protein 1
chr6_+_15720654 0.334 ENSMUST00000101663.3
Mdfic
MyoD family inhibitor domain containing
chr3_+_96221111 0.334 ENSMUST00000090781.6
Hist2h2be
histone cluster 2, H2be
chr11_+_60699718 0.333 ENSMUST00000052346.3
Llgl1
lethal giant larvae homolog 1 (Drosophila)
chr5_+_117841839 0.331 ENSMUST00000142742.2
Nos1
nitric oxide synthase 1, neuronal
chr14_-_104467984 0.329 ENSMUST00000053016.8
Pou4f1
POU domain, class 4, transcription factor 1
chr18_-_52529692 0.326 ENSMUST00000025409.7
Lox
lysyl oxidase
chr11_+_60699758 0.322 ENSMUST00000108719.3
Llgl1
lethal giant larvae homolog 1 (Drosophila)
chr2_+_96318014 0.317 ENSMUST00000135431.1
ENSMUST00000162807.2
Lrrc4c

leucine rich repeat containing 4C

chr2_+_119547697 0.317 ENSMUST00000014221.6
ENSMUST00000119172.1
Chp1

calcineurin-like EF hand protein 1

chr6_-_30693676 0.314 ENSMUST00000169422.1
ENSMUST00000115131.1
ENSMUST00000115130.2
ENSMUST00000031810.8
Cep41



centrosomal protein 41



chr19_+_4231899 0.310 ENSMUST00000025773.3
Pold4
polymerase (DNA-directed), delta 4
chr8_+_45658273 0.306 ENSMUST00000153798.1
Sorbs2
sorbin and SH3 domain containing 2
chr9_+_106429537 0.297 ENSMUST00000059802.6
Rpl29
ribosomal protein L29
chr10_+_33905015 0.293 ENSMUST00000169670.1
Rsph4a
radial spoke head 4 homolog A (Chlamydomonas)
chr4_+_116221689 0.292 ENSMUST00000106490.2
Pik3r3
phosphatidylinositol 3 kinase, regulatory subunit, polypeptide 3 (p55)
chr2_+_70562854 0.288 ENSMUST00000130998.1
Gad1
glutamate decarboxylase 1
chr14_-_54554359 0.276 ENSMUST00000022784.8
Haus4
HAUS augmin-like complex, subunit 4
chr11_-_95699143 0.275 ENSMUST00000062249.2
Gm9796
predicted gene 9796
chr3_+_89436699 0.257 ENSMUST00000038942.3
ENSMUST00000130858.1
Pbxip1

pre B cell leukemia transcription factor interacting protein 1

chr2_+_27079371 0.251 ENSMUST00000091233.6
Adamtsl2
ADAMTS-like 2
chr4_+_128688726 0.250 ENSMUST00000106080.1
Phc2
polyhomeotic-like 2 (Drosophila)
chr9_-_21852603 0.250 ENSMUST00000034728.7
Dock6
dedicator of cytokinesis 6
chr7_+_24862193 0.245 ENSMUST00000052897.4
ENSMUST00000170837.2
Gm9844
Gm9844
predicted pseudogene 9844
predicted pseudogene 9844
chr14_-_25903100 0.244 ENSMUST00000052286.8
Plac9a
placenta specific 9a
chr7_-_45052865 0.244 ENSMUST00000057293.6
Prr12
proline rich 12
chr4_+_133011506 0.243 ENSMUST00000105915.1
ENSMUST00000105916.1
Ahdc1

AT hook, DNA binding motif, containing 1

chr1_-_45503282 0.240 ENSMUST00000086430.4
Col5a2
collagen, type V, alpha 2
chr13_+_23531044 0.238 ENSMUST00000102972.3
Hist1h4h
histone cluster 1, H4h
chr17_+_34263209 0.235 ENSMUST00000040828.5
H2-Ab1
histocompatibility 2, class II antigen A, beta 1
chr3_+_89436736 0.232 ENSMUST00000146630.1
ENSMUST00000145753.1
Pbxip1

pre B cell leukemia transcription factor interacting protein 1

chr4_-_148130678 0.231 ENSMUST00000030862.4
Draxin
dorsal inhibitory axon guidance protein
chr2_+_32628390 0.224 ENSMUST00000156578.1
Ak1
adenylate kinase 1
chr3_+_88607742 0.223 ENSMUST00000175903.1
Arhgef2
rho/rac guanine nucleotide exchange factor (GEF) 2
chr5_+_92683625 0.223 ENSMUST00000168878.1
Shroom3
shroom family member 3
chr7_+_101421691 0.222 ENSMUST00000163751.2
ENSMUST00000084894.7
ENSMUST00000166652.1
Pde2a


phosphodiesterase 2A, cGMP-stimulated


chr5_+_30913398 0.220 ENSMUST00000031055.5
Emilin1
elastin microfibril interfacer 1
chr11_+_60104971 0.209 ENSMUST00000064190.6
Rai1
retinoic acid induced 1
chr6_-_72958465 0.206 ENSMUST00000114050.1
Tmsb10
thymosin, beta 10
chr9_+_13621646 0.203 ENSMUST00000034401.8
Maml2
mastermind like 2 (Drosophila)
chr11_-_69413675 0.203 ENSMUST00000094077.4
Kdm6b
KDM1 lysine (K)-specific demethylase 6B
chr10_-_92164666 0.201 ENSMUST00000183123.1
ENSMUST00000182033.1
Rmst

rhabdomyosarcoma 2 associated transcript (non-coding RNA)

chr14_+_54640952 0.198 ENSMUST00000169818.2
Gm17606
predicted gene, 17606
chr1_-_133801031 0.197 ENSMUST00000143567.1
Atp2b4
ATPase, Ca++ transporting, plasma membrane 4
chr13_-_115090123 0.193 ENSMUST00000109226.3
Pelo
pelota homolog (Drosophila)
chr2_+_27676440 0.186 ENSMUST00000129514.1
Rxra
retinoid X receptor alpha
chrX_-_136741155 0.186 ENSMUST00000166930.1
ENSMUST00000113095.1
ENSMUST00000155207.1
ENSMUST00000080411.6
ENSMUST00000169418.1
Morf4l2




mortality factor 4 like 2




chr15_-_103366763 0.183 ENSMUST00000023128.6
Itga5
integrin alpha 5 (fibronectin receptor alpha)
chr14_+_64950037 0.182 ENSMUST00000043914.5
Ints9
integrator complex subunit 9
chr6_+_54039935 0.181 ENSMUST00000114403.1
Chn2
chimerin (chimaerin) 2
chr5_-_124352233 0.175 ENSMUST00000111472.1
Cdk2ap1
CDK2 (cyclin-dependent kinase 2)-associated protein 1
chr2_+_152736244 0.173 ENSMUST00000038368.8
ENSMUST00000109824.1
Id1

inhibitor of DNA binding 1

chr16_+_34784917 0.170 ENSMUST00000023538.8
Mylk
myosin, light polypeptide kinase
chr7_-_126897424 0.167 ENSMUST00000120007.1
Tmem219
transmembrane protein 219
chr11_+_4637734 0.167 ENSMUST00000109930.2
ENSMUST00000070257.7
Ascc2

activating signal cointegrator 1 complex subunit 2

chr7_+_127485221 0.166 ENSMUST00000048896.6
Fbrs
fibrosin
chr9_-_105521147 0.159 ENSMUST00000176770.1
ENSMUST00000085133.6
Atp2c1

ATPase, Ca++-sequestering

chr5_+_111417263 0.158 ENSMUST00000094463.4
Mn1
meningioma 1
chr15_+_102102926 0.157 ENSMUST00000169627.1
ENSMUST00000046144.9
Tenc1

tensin like C1 domain-containing phosphatase

chr17_-_70851710 0.156 ENSMUST00000166395.2
Tgif1
TGFB-induced factor homeobox 1
chr11_-_3931960 0.152 ENSMUST00000109990.1
ENSMUST00000020710.4
ENSMUST00000109989.3
ENSMUST00000109991.1
ENSMUST00000109993.2
Tcn2




transcobalamin 2




chr13_+_22043189 0.150 ENSMUST00000110452.1
Hist1h2bj
histone cluster 1, H2bj
chr11_+_115420059 0.146 ENSMUST00000103035.3
Kctd2
potassium channel tetramerisation domain containing 2
chr2_+_3114220 0.144 ENSMUST00000072955.5
Fam171a1
family with sequence similarity 171, member A1
chr7_+_110221697 0.143 ENSMUST00000033325.7
Swap70
SWA-70 protein
chr9_+_21424984 0.142 ENSMUST00000172482.1
ENSMUST00000174050.1
Dnm2

dynamin 2

chr5_-_137741102 0.141 ENSMUST00000149512.1
Nyap1
neuronal tyrosine-phosphorylated phosphoinositide 3-kinase adaptor 1
chrX_-_72274747 0.139 ENSMUST00000064780.3
Gabre
gamma-aminobutyric acid (GABA) A receptor, subunit epsilon
chr15_-_93336800 0.138 ENSMUST00000080299.6
Yaf2
YY1 associated factor 2
chr16_-_55283237 0.137 ENSMUST00000036412.3
Zpld1
zona pellucida like domain containing 1
chr4_-_129742275 0.135 ENSMUST00000066257.5
Khdrbs1
KH domain containing, RNA binding, signal transduction associated 1
chr7_+_141216626 0.134 ENSMUST00000141804.1
ENSMUST00000148975.1
Rassf7

Ras association (RalGDS/AF-6) domain family (N-terminal) member 7

chr13_-_21832194 0.134 ENSMUST00000102979.1
Hist1h4n
histone cluster 1, H4n
chr11_-_3931789 0.131 ENSMUST00000109992.1
ENSMUST00000109988.1
Tcn2

transcobalamin 2

chr14_+_57826210 0.127 ENSMUST00000022538.3
Mrp63
mitochondrial ribosomal protein 63
chrX_-_150588071 0.125 ENSMUST00000140207.1
ENSMUST00000112719.1
ENSMUST00000112727.3
ENSMUST00000112721.3
ENSMUST00000026303.9
Apex2




apurinic/apyrimidinic endonuclease 2




chr4_-_148500449 0.118 ENSMUST00000030840.3
Angptl7
angiopoietin-like 7
chr1_-_16770138 0.117 ENSMUST00000071842.8
Gm5828
predicted gene 5828
chr7_-_30362772 0.101 ENSMUST00000046351.5
Lrfn3
leucine rich repeat and fibronectin type III domain containing 3
chr5_-_24445166 0.099 ENSMUST00000115043.1
ENSMUST00000115041.1
Fastk

Fas-activated serine/threonine kinase

chr2_+_69670100 0.098 ENSMUST00000100050.3
Klhl41
kelch-like 41
chr13_-_98891036 0.097 ENSMUST00000109399.2
Tnpo1
transportin 1
chr13_+_21735055 0.095 ENSMUST00000087714.4
Hist1h4j
histone cluster 1, H4j
chr18_-_38918642 0.094 ENSMUST00000040647.4
Fgf1
fibroblast growth factor 1
chr11_+_69846665 0.094 ENSMUST00000019605.2
Plscr3
phospholipid scramblase 3
chr17_-_35162969 0.092 ENSMUST00000174805.1
Prrc2a
proline-rich coiled-coil 2A
chr11_+_115420138 0.089 ENSMUST00000106533.1
ENSMUST00000123345.1
Kctd2

potassium channel tetramerisation domain containing 2

chr9_-_57552760 0.088 ENSMUST00000034856.8
Mpi
mannose phosphate isomerase
chr3_-_146839365 0.088 ENSMUST00000084614.3
Gm10288
predicted gene 10288
chr5_-_24445254 0.087 ENSMUST00000030800.6
Fastk
Fas-activated serine/threonine kinase
chr10_+_18845071 0.086 ENSMUST00000019998.7
Perp
PERP, TP53 apoptosis effector
chr7_+_45785331 0.081 ENSMUST00000120005.1
ENSMUST00000123585.1
Lmtk3

lemur tyrosine kinase 3

chr4_-_134245579 0.076 ENSMUST00000030644.7
Zfp593
zinc finger protein 593
chr7_+_117380937 0.073 ENSMUST00000032892.5
Xylt1
xylosyltransferase 1
chr5_+_7179299 0.073 ENSMUST00000179460.1
Tubb4b-ps1
tubulin, beta 4B class IVB, pseudogene 1
chr7_+_141949982 0.069 ENSMUST00000105989.2
ENSMUST00000075528.5
ENSMUST00000174499.1
Brsk2


BR serine/threonine kinase 2


chr3_-_96220880 0.069 ENSMUST00000090782.3
Hist2h2ac
histone cluster 2, H2ac
chr4_+_126677630 0.068 ENSMUST00000030642.2
Psmb2
proteasome (prosome, macropain) subunit, beta type 2
chr14_-_20496780 0.064 ENSMUST00000022353.3
Mss51
MSS51 mitochondrial translational activator
chr2_+_69897220 0.064 ENSMUST00000055758.9
ENSMUST00000112251.2
Ubr3

ubiquitin protein ligase E3 component n-recognin 3

chr15_-_38300693 0.061 ENSMUST00000074043.5
Klf10
Kruppel-like factor 10
chr17_+_46646225 0.059 ENSMUST00000002844.7
ENSMUST00000113429.1
ENSMUST00000113430.1
Mrpl2


mitochondrial ribosomal protein L2


chr2_-_128967725 0.058 ENSMUST00000099385.2
Gm10762
predicted gene 10762
chr7_+_141949846 0.055 ENSMUST00000172652.1
Brsk2
BR serine/threonine kinase 2
chr9_+_61373219 0.051 ENSMUST00000162583.1
ENSMUST00000161993.1
ENSMUST00000160882.1
ENSMUST00000160724.1
ENSMUST00000162973.1
ENSMUST00000159050.1
Tle3





transducin-like enhancer of split 3, homolog of Drosophila E(spl)





chr9_+_61373482 0.048 ENSMUST00000160541.1
ENSMUST00000161207.1
ENSMUST00000159630.1
Tle3


transducin-like enhancer of split 3, homolog of Drosophila E(spl)


chr19_+_46328179 0.047 ENSMUST00000026256.2
ENSMUST00000177667.1
Fbxl15

F-box and leucine-rich repeat protein 15

chr3_+_36552600 0.047 ENSMUST00000029269.5
ENSMUST00000136890.1
Exosc9

exosome component 9

chr1_-_74588117 0.046 ENSMUST00000066986.6
Zfp142
zinc finger protein 142
chr2_-_29869785 0.044 ENSMUST00000047607.1
2600006K01Rik
RIKEN cDNA 2600006K01 gene
chrX_+_151803313 0.042 ENSMUST00000026292.8
Huwe1
HECT, UBA and WWE domain containing 1
chr1_+_74588347 0.041 ENSMUST00000113732.1
Bcs1l
BCS1-like (yeast)
chr17_+_34145231 0.040 ENSMUST00000171231.1
H2-DMb2
histocompatibility 2, class II, locus Mb2
chr18_+_60526194 0.038 ENSMUST00000025505.5
Dctn4
dynactin 4
chr1_-_173367638 0.036 ENSMUST00000005470.4
ENSMUST00000111220.1
Cadm3

cell adhesion molecule 3

chr11_+_4160348 0.036 ENSMUST00000002198.3
Sf3a1
splicing factor 3a, subunit 1
chr13_-_23934156 0.034 ENSMUST00000052776.2
Hist1h2ba
histone cluster 1, H2ba
chr2_+_128967383 0.032 ENSMUST00000110320.2
ENSMUST00000110319.2
Zc3h6

zinc finger CCCH type containing 6

chrX_+_136270253 0.031 ENSMUST00000178632.1
ENSMUST00000053540.4
Ngfrap1

nerve growth factor receptor (TNFRSF16) associated protein 1

chr2_+_120476911 0.030 ENSMUST00000110716.1
ENSMUST00000028748.6
ENSMUST00000090028.5
ENSMUST00000110719.2
Capn3



calpain 3



chr4_-_119190005 0.028 ENSMUST00000138395.1
ENSMUST00000156746.1
Ermap

erythroblast membrane-associated protein

chr4_-_117178726 0.028 ENSMUST00000153953.1
ENSMUST00000106436.1
Kif2c

kinesin family member 2C

chr7_+_4690760 0.024 ENSMUST00000048248.7
Brsk1
BR serine/threonine kinase 1
chr9_-_20898592 0.024 ENSMUST00000004206.8
Eif3g
eukaryotic translation initiation factor 3, subunit G
chr14_-_64949838 0.022 ENSMUST00000067843.3
ENSMUST00000176489.1
ENSMUST00000175905.1
ENSMUST00000022544.7
ENSMUST00000175744.1
ENSMUST00000176128.1
Hmbox1





homeobox containing 1





chr2_+_29869484 0.022 ENSMUST00000047521.6
ENSMUST00000134152.1
Cercam

cerebral endothelial cell adhesion molecule

chr11_-_106160708 0.022 ENSMUST00000106875.1
Limd2
LIM domain containing 2
chr7_+_83755904 0.022 ENSMUST00000051522.8
ENSMUST00000042280.7
Gm7964

predicted gene 7964

chr10_+_80300997 0.021 ENSMUST00000140828.1
ENSMUST00000138909.1
Apc2

adenomatosis polyposis coli 2

chr5_+_121795034 0.018 ENSMUST00000162327.1
Atxn2
ataxin 2
chr9_+_61373608 0.018 ENSMUST00000161689.1
Tle3
transducin-like enhancer of split 3, homolog of Drosophila E(spl)
chr6_+_38433913 0.016 ENSMUST00000160583.1
Ubn2
ubinuclein 2
chr14_-_18331855 0.015 ENSMUST00000022296.6
Ube2e1
ubiquitin-conjugating enzyme E2E 1
chr7_+_123377982 0.013 ENSMUST00000033025.5
Lcmt1
leucine carboxyl methyltransferase 1
chr7_+_82867327 0.011 ENSMUST00000082237.5
Mex3b
mex3 homolog B (C. elegans)
chr11_-_115419917 0.007 ENSMUST00000106537.1
ENSMUST00000043931.2
ENSMUST00000073791.3
Atp5h


ATP synthase, H+ transporting, mitochondrial F0 complex, subunit d


chr11_+_69846610 0.007 ENSMUST00000152566.1
ENSMUST00000108633.2
Plscr3

phospholipid scramblase 3

chr13_-_22042949 0.006 ENSMUST00000091741.4
Hist1h2ag
histone cluster 1, H2ag
chr6_+_54039558 0.004 ENSMUST00000046856.7
Chn2
chimerin (chimaerin) 2
chr11_-_106160101 0.002 ENSMUST00000045923.3
Limd2
LIM domain containing 2
chr3_+_94837533 0.002 ENSMUST00000107270.2
Pogz
pogo transposable element with ZNF domain

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 3.0 GO:2000546 positive regulation of cell chemotaxis to fibroblast growth factor(GO:1904849) positive regulation of endothelial cell chemotaxis to fibroblast growth factor(GO:2000546)
0.4 1.3 GO:1905065 hematopoietic stem cell migration(GO:0035701) positive regulation of vascular smooth muscle cell differentiation(GO:1905065)
0.3 1.0 GO:1902460 regulation of mesenchymal stem cell proliferation(GO:1902460) positive regulation of mesenchymal stem cell proliferation(GO:1902462)
0.2 3.1 GO:0060159 regulation of dopamine receptor signaling pathway(GO:0060159)
0.2 0.7 GO:0003219 cardiac right ventricle formation(GO:0003219)
0.2 0.8 GO:0097709 connective tissue replacement involved in inflammatory response wound healing(GO:0002248) connective tissue replacement(GO:0097709)
0.2 0.9 GO:0014719 skeletal muscle satellite cell activation(GO:0014719)
0.2 0.3 GO:0070885 negative regulation of calcineurin-NFAT signaling cascade(GO:0070885)
0.1 0.7 GO:0021764 amygdala development(GO:0021764)
0.1 0.4 GO:0014005 microglia differentiation(GO:0014004) microglia development(GO:0014005)
0.1 0.7 GO:0060838 lymphatic endothelial cell fate commitment(GO:0060838) regulation of transcription involved in lymphatic endothelial cell fate commitment(GO:0060849)
0.1 0.5 GO:1901204 regulation of adrenergic receptor signaling pathway involved in heart process(GO:1901204)
0.1 0.2 GO:0033159 negative regulation of protein import into nucleus, translocation(GO:0033159)
0.1 0.3 GO:0015889 cobalamin transport(GO:0015889)
0.1 0.7 GO:0019370 leukotriene biosynthetic process(GO:0019370)
0.1 1.8 GO:0048368 lateral mesoderm development(GO:0048368)
0.1 0.5 GO:0010991 negative regulation of SMAD protein complex assembly(GO:0010991)
0.1 0.4 GO:0035331 negative regulation of hippo signaling(GO:0035331)
0.1 0.2 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
0.1 0.7 GO:0048251 elastic fiber assembly(GO:0048251)
0.1 0.2 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.1 0.4 GO:2000623 regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.1 0.1 GO:1903351 response to dopamine(GO:1903350) cellular response to dopamine(GO:1903351)
0.1 0.5 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.1 0.3 GO:0003223 ventricular compact myocardium morphogenesis(GO:0003223) proprioception(GO:0019230)
0.1 0.7 GO:0035090 maintenance of apical/basal cell polarity(GO:0035090)
0.1 0.2 GO:0002339 B cell selection(GO:0002339)
0.1 0.5 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.0 0.3 GO:1903300 negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300)
0.0 0.1 GO:2000544 cell chemotaxis to fibroblast growth factor(GO:0035766) endothelial cell chemotaxis to fibroblast growth factor(GO:0035768) regulation of cell chemotaxis to fibroblast growth factor(GO:1904847) regulation of endothelial cell chemotaxis to fibroblast growth factor(GO:2000544)
0.0 0.1 GO:0032241 positive regulation of nucleobase-containing compound transport(GO:0032241)
0.0 0.4 GO:0045607 regulation of auditory receptor cell differentiation(GO:0045607) regulation of mechanoreceptor differentiation(GO:0045631) regulation of inner ear receptor cell differentiation(GO:2000980)
0.0 0.2 GO:1903026 negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903026)
0.0 0.5 GO:0033690 positive regulation of osteoblast proliferation(GO:0033690)
0.0 0.2 GO:0055071 cellular manganese ion homeostasis(GO:0030026) Golgi calcium ion homeostasis(GO:0032468) manganese ion homeostasis(GO:0055071)
0.0 0.2 GO:0070966 nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966)
0.0 0.2 GO:0006172 ADP biosynthetic process(GO:0006172)
0.0 0.2 GO:0006447 regulation of translational initiation by iron(GO:0006447) positive regulation of translational initiation by iron(GO:0045994)
0.0 0.3 GO:0033631 cell-cell adhesion mediated by integrin(GO:0033631)
0.0 0.7 GO:0032967 positive regulation of collagen biosynthetic process(GO:0032967)
0.0 0.5 GO:0050966 detection of mechanical stimulus involved in sensory perception of pain(GO:0050966)
0.0 0.3 GO:0002227 innate immune response in mucosa(GO:0002227)
0.0 0.5 GO:0070498 interleukin-1-mediated signaling pathway(GO:0070498)
0.0 0.1 GO:0009298 GDP-mannose biosynthetic process(GO:0009298)
0.0 1.0 GO:0043551 regulation of phosphatidylinositol 3-kinase activity(GO:0043551)
0.0 0.2 GO:0036072 intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.0 0.5 GO:0031295 lymphocyte costimulation(GO:0031294) T cell costimulation(GO:0031295)
0.0 0.2 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.0 0.2 GO:0071225 cellular response to muramyl dipeptide(GO:0071225)
0.0 1.2 GO:0045600 positive regulation of fat cell differentiation(GO:0045600)
0.0 0.4 GO:0010225 response to UV-C(GO:0010225)
0.0 0.3 GO:0060481 lobar bronchus epithelium development(GO:0060481)
0.0 0.1 GO:0002934 desmosome organization(GO:0002934)
0.0 0.4 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.0 0.3 GO:0000731 DNA synthesis involved in DNA repair(GO:0000731)
0.0 0.1 GO:0071596 ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596)
0.0 0.0 GO:0034476 U1 snRNA 3'-end processing(GO:0034473) U5 snRNA 3'-end processing(GO:0034476)
0.0 0.2 GO:0038092 nodal signaling pathway(GO:0038092)
0.0 0.1 GO:0060325 face morphogenesis(GO:0060325)
0.0 0.2 GO:0050434 positive regulation of viral transcription(GO:0050434)
0.0 0.0 GO:0000389 mRNA 3'-splice site recognition(GO:0000389)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0038045 large latent transforming growth factor-beta complex(GO:0038045)
0.2 0.5 GO:0043540 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex(GO:0043540)
0.1 0.4 GO:0070939 Dsl1p complex(GO:0070939)
0.1 0.3 GO:0043625 delta DNA polymerase complex(GO:0043625)
0.1 0.2 GO:0005588 collagen type V trimer(GO:0005588)
0.1 0.2 GO:0044302 dentate gyrus mossy fiber(GO:0044302)
0.1 2.5 GO:0032809 neuronal cell body membrane(GO:0032809)
0.1 0.7 GO:0043083 synaptic cleft(GO:0043083)
0.1 0.7 GO:0000137 Golgi cis cisterna(GO:0000137)
0.0 1.0 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 0.3 GO:0042613 MHC class II protein complex(GO:0042613)
0.0 1.0 GO:0001891 phagocytic cup(GO:0001891)
0.0 0.7 GO:0071564 npBAF complex(GO:0071564)
0.0 0.3 GO:0070652 HAUS complex(GO:0070652)
0.0 0.5 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.3 GO:0042582 primary lysosome(GO:0005766) azurophil granule(GO:0042582)
0.0 0.2 GO:0001520 outer dense fiber(GO:0001520)
0.0 0.3 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 0.3 GO:0042788 polysomal ribosome(GO:0042788)
0.0 1.2 GO:0005581 collagen trimer(GO:0005581)
0.0 0.5 GO:0000788 nuclear nucleosome(GO:0000788)
0.0 0.3 GO:0035102 PRC1 complex(GO:0035102)
0.0 0.3 GO:0030134 ER to Golgi transport vesicle(GO:0030134)
0.0 0.2 GO:0032039 integrator complex(GO:0032039)
0.0 0.4 GO:0043209 myelin sheath(GO:0043209)
0.0 0.2 GO:0097228 sperm principal piece(GO:0097228)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 3.0 GO:0005105 type 1 fibroblast growth factor receptor binding(GO:0005105)
0.2 1.0 GO:0050436 microfibril binding(GO:0050436)
0.2 0.7 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.2 1.3 GO:0004716 receptor signaling protein tyrosine kinase activity(GO:0004716)
0.1 1.0 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.1 0.3 GO:0004517 nitric-oxide synthase activity(GO:0004517)
0.1 0.7 GO:0004971 AMPA glutamate receptor activity(GO:0004971)
0.1 0.7 GO:0001972 retinoic acid binding(GO:0001972)
0.1 0.5 GO:0070095 fructose-6-phosphate binding(GO:0070095)
0.1 3.1 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.1 0.2 GO:0036004 GAF domain binding(GO:0036004)
0.1 0.9 GO:0044548 S100 protein binding(GO:0044548)
0.1 0.7 GO:0016755 transferase activity, transferring amino-acyl groups(GO:0016755)
0.0 1.0 GO:0050431 transforming growth factor beta binding(GO:0050431)
0.0 0.5 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.0 0.1 GO:0008311 double-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008311)
0.0 0.3 GO:0031419 cobalamin binding(GO:0031419)
0.0 0.2 GO:0015410 manganese-transporting ATPase activity(GO:0015410)
0.0 0.4 GO:0045294 alpha-catenin binding(GO:0045294)
0.0 0.2 GO:0070644 vitamin D response element binding(GO:0070644)
0.0 0.3 GO:0030957 Tat protein binding(GO:0030957)
0.0 0.2 GO:0015643 toxic substance binding(GO:0015643)
0.0 0.2 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 0.1 GO:0030158 protein xylosyltransferase activity(GO:0030158)
0.0 0.2 GO:0004017 adenylate kinase activity(GO:0004017)
0.0 0.6 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.3 GO:0005035 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.0 0.7 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.0 0.4 GO:0097602 cullin family protein binding(GO:0097602)
0.0 0.1 GO:0031749 D2 dopamine receptor binding(GO:0031749)
0.0 0.5 GO:0017147 Wnt-protein binding(GO:0017147)
0.0 0.6 GO:0070888 E-box binding(GO:0070888)
0.0 0.2 GO:0070410 co-SMAD binding(GO:0070410)
0.0 0.2 GO:0070182 DNA polymerase binding(GO:0070182)
0.0 1.0 GO:0035250 UDP-galactosyltransferase activity(GO:0035250)
0.0 0.5 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.3 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.0 0.4 GO:0070412 R-SMAD binding(GO:0070412)