Motif ID: Smarcc1_Fosl1

Z-value: 0.781

Transcription factors associated with Smarcc1_Fosl1:

Gene SymbolEntrez IDGene Name
Fosl1 ENSMUSG00000024912.5 Fosl1
Smarcc1 ENSMUSG00000032481.10 Smarcc1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Fosl1mm10_v2_chr19_+_5447692_54477110.156.0e-01Click!
Smarcc1mm10_v2_chr9_+_110132015_1101321020.029.5e-01Click!


Activity profile for motif Smarcc1_Fosl1.

activity profile for motif Smarcc1_Fosl1


Sorted Z-values histogram for motif Smarcc1_Fosl1

Sorted Z-values for motif Smarcc1_Fosl1



Network of associatons between targets according to the STRING database.



First level regulatory network of Smarcc1_Fosl1

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr10_-_64090241 1.486 ENSMUST00000133588.1
 Lrrtm3
leucine rich repeat transmembrane neuronal 3
chr14_-_62454793 0.863 ENSMUST00000128573.1
 Gucy1b2
guanylate cyclase 1, soluble, beta 2
chr10_-_64090265 0.834 ENSMUST00000105439.1
 Lrrtm3
leucine rich repeat transmembrane neuronal 3
chr10_+_97565436 0.829 ENSMUST00000038160.4
 Lum
lumican
chr18_-_66860458 0.760 ENSMUST00000057942.2
 Mc4r
melanocortin 4 receptor
chr2_-_62483637 0.757 ENSMUST00000136686.1
ENSMUST00000102733.3
 Gcg

glucagon

chr17_+_55952623 0.754 ENSMUST00000003274.6
 Ebi3
Epstein-Barr virus induced gene 3
chr12_-_74316394 0.744 ENSMUST00000110441.1
 Gm11042
predicted gene 11042
chrX_-_135598758 0.642 ENSMUST00000150900.1
ENSMUST00000113163.1
 Nxf7

nuclear RNA export factor 7

chr2_+_13573927 0.521 ENSMUST00000141365.1
ENSMUST00000028062.2
 Vim

vimentin

chr1_-_33907721 0.519 ENSMUST00000115161.1
ENSMUST00000062289.8
 Bend6

BEN domain containing 6

chr7_+_30413744 0.515 ENSMUST00000032800.9
 Tyrobp
TYRO protein tyrosine kinase binding protein
chr6_+_104492790 0.510 ENSMUST00000161446.1
ENSMUST00000161070.1
ENSMUST00000089215.5
 Cntn6


contactin 6


chr1_-_183147461 0.509 ENSMUST00000171366.1
 Disp1
dispatched homolog 1 (Drosophila)
chr10_-_76725978 0.496 ENSMUST00000001147.4
 Col6a1
collagen, type VI, alpha 1
chr3_-_116129615 0.434 ENSMUST00000029574.8
 Vcam1
vascular cell adhesion molecule 1
chr10_+_86779000 0.413 ENSMUST00000099396.2
 Nt5dc3
5'-nucleotidase domain containing 3
chr2_+_32775769 0.394 ENSMUST00000066352.5
 Ptrh1
peptidyl-tRNA hydrolase 1 homolog (S. cerevisiae)
chr8_+_23035116 0.392 ENSMUST00000117296.1
ENSMUST00000141784.2
 Ank1

ankyrin 1, erythroid

chr7_+_126766397 0.390 ENSMUST00000032944.7
 Gdpd3
glycerophosphodiester phosphodiesterase domain containing 3

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 302 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 3.1 GO:1902993 positive regulation of beta-amyloid formation(GO:1902004) positive regulation of amyloid precursor protein catabolic process(GO:1902993)
0.2 0.8 GO:0032914 positive regulation of transforming growth factor beta1 production(GO:0032914)
0.2 0.8 GO:0002024 diet induced thermogenesis(GO:0002024) adaptive thermogenesis(GO:1990845)
0.0 0.8 GO:0033014 porphyrin-containing compound biosynthetic process(GO:0006779) tetrapyrrole biosynthetic process(GO:0033014)
0.1 0.7 GO:0060539 diaphragm development(GO:0060539)
0.0 0.7 GO:0030213 hyaluronan biosynthetic process(GO:0030213)
0.0 0.7 GO:0040015 negative regulation of multicellular organism growth(GO:0040015)
0.2 0.6 GO:0090298 positive regulation of fat cell proliferation(GO:0070346) negative regulation of mitochondrial DNA replication(GO:0090298)
0.1 0.6 GO:0032804 negative regulation of low-density lipoprotein particle receptor catabolic process(GO:0032804)
0.1 0.6 GO:0035948 positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter(GO:0035948) regulation of cellular ketone metabolic process by positive regulation of transcription from RNA polymerase II promoter(GO:0072366)
0.1 0.6 GO:0032264 IMP salvage(GO:0032264)
0.1 0.6 GO:0006183 GTP biosynthetic process(GO:0006183)
0.0 0.6 GO:0006000 fructose metabolic process(GO:0006000)
0.0 0.6 GO:0016973 poly(A)+ mRNA export from nucleus(GO:0016973)
0.0 0.6 GO:0070208 protein heterotrimerization(GO:0070208)
0.1 0.5 GO:1900147 Schwann cell migration(GO:0036135) regulation of Schwann cell migration(GO:1900147)
0.1 0.5 GO:2001204 regulation of osteoclast development(GO:2001204)
0.1 0.5 GO:0006172 ADP biosynthetic process(GO:0006172)
0.1 0.5 GO:0038028 insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028)
0.1 0.5 GO:0060164 regulation of timing of neuron differentiation(GO:0060164)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 116 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 1.2 GO:0005581 collagen trimer(GO:0005581)
0.1 0.9 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.0 0.9 GO:0070469 respiratory chain(GO:0070469)
0.1 0.8 GO:0034366 spherical high-density lipoprotein particle(GO:0034366) neurofibrillary tangle(GO:0097418)
0.1 0.8 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.0 0.8 GO:0031430 M band(GO:0031430)
0.0 0.8 GO:0005844 polysome(GO:0005844)
0.0 0.7 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0 0.6 GO:0008540 proteasome regulatory particle, base subcomplex(GO:0008540)
0.2 0.5 GO:1990667 PCSK9-AnxA2 complex(GO:1990667)
0.1 0.5 GO:0045098 type III intermediate filament(GO:0045098)
0.1 0.5 GO:0001520 outer dense fiber(GO:0001520)
0.1 0.5 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.0 0.5 GO:0044322 endoplasmic reticulum quality control compartment(GO:0044322)
0.0 0.5 GO:0002102 podosome(GO:0002102)
0.0 0.5 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.1 0.4 GO:1990682 CSF1-CSF1R complex(GO:1990682)
0.1 0.4 GO:0016461 unconventional myosin complex(GO:0016461)
0.1 0.4 GO:0005638 lamin filament(GO:0005638)
0.0 0.4 GO:0031931 TORC1 complex(GO:0031931)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 193 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 2.9 GO:0004860 protein kinase inhibitor activity(GO:0004860)
0.0 1.6 GO:0005179 hormone activity(GO:0005179)
0.1 1.2 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
0.0 1.2 GO:0005518 collagen binding(GO:0005518)
0.0 1.0 GO:0005125 cytokine activity(GO:0005125)
0.0 0.9 GO:0097472 cyclin-dependent protein serine/threonine kinase activity(GO:0004693) cyclin-dependent protein kinase activity(GO:0097472)
0.3 0.8 GO:0004980 melanocortin receptor activity(GO:0004977) melanocyte-stimulating hormone receptor activity(GO:0004980)
0.1 0.8 GO:0004383 guanylate cyclase activity(GO:0004383)
0.0 0.8 GO:0051787 misfolded protein binding(GO:0051787)
0.1 0.6 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0 0.6 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.0 0.6 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.0 0.6 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 0.6 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 0.6 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.1 0.5 GO:0004859 phospholipase inhibitor activity(GO:0004859) phospholipase A2 inhibitor activity(GO:0019834)
0.1 0.5 GO:1990254 keratin filament binding(GO:1990254)
0.1 0.5 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
0.0 0.5 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.0 0.5 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)