Motif ID: Sox1

Z-value: 0.495


Transcription factors associated with Sox1:

Gene SymbolEntrez IDGene Name
Sox1 ENSMUSG00000096014.1 Sox1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Sox1mm10_v2_chr8_+_12395287_123952950.679.0e-03Click!


Activity profile for motif Sox1.

activity profile for motif Sox1


Sorted Z-values histogram for motif Sox1

Sorted Z-values for motif Sox1



Network of associatons between targets according to the STRING database.



First level regulatory network of Sox1

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr15_-_75048837 1.762 ENSMUST00000179762.1
ENSMUST00000065408.9
Ly6c1

lymphocyte antigen 6 complex, locus C1

chr3_-_34005490 1.196 ENSMUST00000060997.2
Gm9791
predicted pseudogene 9791
chr15_-_74997634 0.974 ENSMUST00000023248.6
Ly6a
lymphocyte antigen 6 complex, locus A
chr17_+_47737030 0.775 ENSMUST00000086932.3
Tfeb
transcription factor EB
chr7_+_80343091 0.597 ENSMUST00000032747.5
Hddc3
HD domain containing 3
chr17_-_47692466 0.410 ENSMUST00000113300.1
Prickle4
prickle homolog 4 (Drosophila)
chr16_-_37654408 0.389 ENSMUST00000023514.3
Ndufb4
NADH dehydrogenase (ubiquinone) 1 beta subcomplex 4
chr9_-_108305941 0.378 ENSMUST00000044725.7
Tcta
T cell leukemia translocation altered gene
chr17_+_34969912 0.376 ENSMUST00000173680.1
Gm20481
predicted gene 20481
chr10_+_84756055 0.364 ENSMUST00000060397.6
Rfx4
regulatory factor X, 4 (influences HLA class II expression)
chr7_+_101896340 0.296 ENSMUST00000035395.7
ENSMUST00000106973.1
ENSMUST00000144207.1
Anapc15


anaphase prompoting complex C subunit 15


chr5_+_21186267 0.275 ENSMUST00000036031.8
Gsap
gamma-secretase activating protein
chr4_+_136357423 0.242 ENSMUST00000182167.1
Gm17388
predicted gene, 17388
chr11_-_68853119 0.237 ENSMUST00000018880.7
Ndel1
nuclear distribution gene E-like homolog 1 (A. nidulans)
chr6_+_117841174 0.216 ENSMUST00000112859.1
ENSMUST00000137224.1
ENSMUST00000164472.1
ENSMUST00000112861.1
ENSMUST00000035638.8
Zfp637




zinc finger protein 637




chr7_-_57509995 0.213 ENSMUST00000068456.6
Gabra5
gamma-aminobutyric acid (GABA) A receptor, subunit alpha 5
chr9_-_114390633 0.213 ENSMUST00000084881.4
Crtap
cartilage associated protein
chr14_-_30923547 0.210 ENSMUST00000170415.1
Itih3
inter-alpha trypsin inhibitor, heavy chain 3
chr7_+_119690026 0.206 ENSMUST00000047045.8
Acsm4
acyl-CoA synthetase medium-chain family member 4
chr7_-_127890918 0.188 ENSMUST00000121394.1
Prss53
protease, serine, 53
chr17_+_34263209 0.132 ENSMUST00000040828.5
H2-Ab1
histocompatibility 2, class II antigen A, beta 1
chr6_+_114648811 0.130 ENSMUST00000182510.1
Atg7
autophagy related 7
chrX_+_74297097 0.121 ENSMUST00000019231.5
ENSMUST00000147900.1
ENSMUST00000147275.1
ENSMUST00000114171.3
Atp6ap1



ATPase, H+ transporting, lysosomal accessory protein 1



chr6_+_121183667 0.092 ENSMUST00000118234.1
ENSMUST00000088561.3
ENSMUST00000137432.1
ENSMUST00000120066.1
Pex26



peroxisomal biogenesis factor 26



chr17_-_34287770 0.088 ENSMUST00000174751.1
ENSMUST00000040655.6
H2-Aa

histocompatibility 2, class II antigen A, alpha

chr7_-_46919915 0.070 ENSMUST00000143413.1
ENSMUST00000014546.8
Tsg101

tumor susceptibility gene 101

chr18_+_37496997 0.067 ENSMUST00000059571.5
Pcdhb19
protocadherin beta 19
chr14_-_30923754 0.063 ENSMUST00000006697.8
Itih3
inter-alpha trypsin inhibitor, heavy chain 3
chr8_+_13159135 0.033 ENSMUST00000033824.6
Lamp1
lysosomal-associated membrane protein 1
chr5_-_13121766 0.026 ENSMUST00000078246.4
Gm10108
predicted pseudogene 10108
chr11_-_68853019 0.016 ENSMUST00000108672.1
Ndel1
nuclear distribution gene E-like homolog 1 (A. nidulans)
chr7_+_67655414 0.007 ENSMUST00000107470.1
Ttc23
tetratricopeptide repeat domain 23
chr5_-_140649018 0.002 ENSMUST00000042661.3
Ttyh3
tweety homolog 3 (Drosophila)

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0034035 purine ribonucleoside bisphosphate metabolic process(GO:0034035)
0.1 0.4 GO:0021914 negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021914)
0.0 0.1 GO:0039521 suppression by virus of host autophagy(GO:0039521) negative regulation of sphingolipid biosynthesis involved in cellular sphingolipid homeostasis(GO:0090157)
0.0 0.3 GO:0030397 membrane disassembly(GO:0030397) nuclear envelope disassembly(GO:0051081)
0.0 0.1 GO:2001206 positive regulation of osteoclast development(GO:2001206)
0.0 0.1 GO:0002339 B cell selection(GO:0002339)
0.0 0.1 GO:1903774 positive regulation of viral budding via host ESCRT complex(GO:1903774)
0.0 0.3 GO:1903504 regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090266) regulation of mitotic spindle checkpoint(GO:1903504)
0.0 0.2 GO:0019511 peptidyl-proline hydroxylation(GO:0019511)
0.0 0.3 GO:1902993 positive regulation of beta-amyloid formation(GO:1902004) positive regulation of amyloid precursor protein catabolic process(GO:1902993)
0.0 0.1 GO:0015919 peroxisomal membrane transport(GO:0015919) protein import into peroxisome membrane(GO:0045046)
0.0 0.0 GO:0008626 granzyme-mediated apoptotic signaling pathway(GO:0008626) positive regulation of natural killer cell degranulation(GO:0043323)
0.0 0.8 GO:0080171 lysosome organization(GO:0007040) lytic vacuole organization(GO:0080171)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 GO:0060053 neurofilament cytoskeleton(GO:0060053)
0.0 0.2 GO:0042613 MHC class II protein complex(GO:0042613)
0.0 2.7 GO:0031225 anchored component of membrane(GO:0031225)
0.0 0.1 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.0 0.2 GO:1902710 GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711)
0.0 0.3 GO:0005680 anaphase-promoting complex(GO:0005680)
0.0 0.0 GO:0044194 cytolytic granule(GO:0044194)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 GO:0016778 diphosphotransferase activity(GO:0016778)
0.1 0.3 GO:0070012 oligopeptidase activity(GO:0070012)
0.1 0.2 GO:0047760 butyrate-CoA ligase activity(GO:0047760)
0.0 0.1 GO:0019779 Atg12 activating enzyme activity(GO:0019778) Atg8 activating enzyme activity(GO:0019779)
0.0 0.1 GO:0015643 toxic substance binding(GO:0015643)
0.0 0.2 GO:0050811 GABA-A receptor activity(GO:0004890) GABA receptor binding(GO:0050811)
0.0 0.1 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)