Motif ID: Sox11

Z-value: 0.610


Transcription factors associated with Sox11:

Gene SymbolEntrez IDGene Name
Sox11 ENSMUSG00000063632.5 Sox11

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Sox11mm10_v2_chr12_-_27342696_273427260.696.2e-03Click!


Activity profile for motif Sox11.

activity profile for motif Sox11


Sorted Z-values histogram for motif Sox11

Sorted Z-values for motif Sox11



Network of associatons between targets according to the STRING database.



First level regulatory network of Sox11

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr9_-_16378231 3.096 ENSMUST00000082170.5
 Fat3
FAT tumor suppressor homolog 3 (Drosophila)
chr9_+_89909775 2.356 ENSMUST00000034912.4
ENSMUST00000034909.4
 Rasgrf1

RAS protein-specific guanine nucleotide-releasing factor 1

chr16_-_44558864 1.335 ENSMUST00000023370.4
 Boc
biregional cell adhesion molecule-related/down-regulated by oncogenes (Cdon) binding protein
chr13_-_99516537 1.245 ENSMUST00000064762.4
 Map1b
microtubule-associated protein 1B
chr16_-_44558879 1.094 ENSMUST00000114634.1
 Boc
biregional cell adhesion molecule-related/down-regulated by oncogenes (Cdon) binding protein
chr11_+_69364010 1.061 ENSMUST00000166700.1
 Gm17305
predicted gene, 17305
chr6_-_136173492 1.029 ENSMUST00000111905.1
 Grin2b
glutamate receptor, ionotropic, NMDA2B (epsilon 2)
chr2_+_154548888 0.965 ENSMUST00000045116.4
ENSMUST00000109709.3
 1700003F12Rik

RIKEN cDNA 1700003F12 gene

chr7_+_70388305 0.889 ENSMUST00000080024.5
 B130024G19Rik
RIKEN cDNA B130024G19 gene
chr15_+_76797628 0.839 ENSMUST00000165535.2
 Gm17271
predicted gene, 17271
chr5_+_14514918 0.828 ENSMUST00000030691.10
ENSMUST00000182407.1
 Pclo

piccolo (presynaptic cytomatrix protein)

chr11_-_69369377 0.792 ENSMUST00000092971.6
ENSMUST00000108661.1
 Chd3

chromodomain helicase DNA binding protein 3

chr10_+_119992916 0.696 ENSMUST00000105261.2
 Grip1
glutamate receptor interacting protein 1
chr5_-_131616599 0.672 ENSMUST00000161804.1
 Auts2
autism susceptibility candidate 2
chr4_-_97584612 0.661 ENSMUST00000107068.2
 E130114P18Rik
RIKEN cDNA E130114P18 gene
chr4_-_97584605 0.640 ENSMUST00000107067.1
 E130114P18Rik
RIKEN cDNA E130114P18 gene
chr16_+_8830093 0.631 ENSMUST00000023150.5
 1810013L24Rik
RIKEN cDNA 1810013L24 gene
chr16_-_50330987 0.610 ENSMUST00000114488.1
 Bbx
bobby sox homolog (Drosophila)
chr4_-_44072578 0.601 ENSMUST00000173383.1
 Gne
glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase
chr5_+_8046077 0.546 ENSMUST00000088786.4
 Sri
sorcin
chr8_-_34965631 0.514 ENSMUST00000033929.4
 Tnks
tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase
chr3_+_67430096 0.513 ENSMUST00000077271.6
ENSMUST00000161009.1
 Gfm1

G elongation factor, mitochondrial 1

chr14_-_52213379 0.503 ENSMUST00000140603.1
 Chd8
chromodomain helicase DNA binding protein 8
chr2_+_3114220 0.503 ENSMUST00000072955.5
 Fam171a1
family with sequence similarity 171, member A1
chr9_+_32116040 0.492 ENSMUST00000174641.1
 Arhgap32
Rho GTPase activating protein 32
chr3_+_60877002 0.441 ENSMUST00000099086.2
 Gm8325
predicted pseudogene 8325
chr7_-_55962466 0.408 ENSMUST00000032635.7
ENSMUST00000152649.1
 Nipa2

non imprinted in Prader-Willi/Angelman syndrome 2 homolog (human)

chr9_+_107888129 0.393 ENSMUST00000035202.2
 Mon1a
MON1 homolog A (yeast)
chr1_+_44119952 0.377 ENSMUST00000114709.2
 Bivm
basic, immunoglobulin-like variable motif containing
chr11_+_4873951 0.354 ENSMUST00000038570.2
 Nipsnap1
4-nitrophenylphosphatase domain and non-neuronal SNAP25-like protein homolog 1 (C. elegans)
chr6_-_12109583 0.305 ENSMUST00000080891.5
 Gm6578
predicted gene 6578
chr17_-_29007925 0.304 ENSMUST00000009138.5
ENSMUST00000119274.1
 Stk38

serine/threonine kinase 38

chr2_-_36136773 0.302 ENSMUST00000028251.3
 Rbm18
RNA binding motif protein 18
chr2_-_127247620 0.299 ENSMUST00000174030.1
ENSMUST00000174863.1
 Ciao1

cytosolic iron-sulfur protein assembly 1

chr7_-_105737376 0.276 ENSMUST00000098148.4
 Rrp8
ribosomal RNA processing 8, methyltransferase, homolog (yeast)
chr6_-_42693087 0.269 ENSMUST00000121083.1
 Fam115a
family with sequence similarity 115, member A
chr17_+_43016536 0.264 ENSMUST00000024708.4
 Tnfrsf21
tumor necrosis factor receptor superfamily, member 21
chr2_-_36136602 0.252 ENSMUST00000122456.1
 Rbm18
RNA binding motif protein 18
chr6_-_42693030 0.244 ENSMUST00000045140.4
 Fam115a
family with sequence similarity 115, member A
chr11_-_106193511 0.242 ENSMUST00000007444.7
ENSMUST00000152008.1
ENSMUST00000103072.3
ENSMUST00000106867.1
 Strada



STE20-related kinase adaptor alpha



chr6_-_23248264 0.240 ENSMUST00000031709.5
 Fezf1
Fez family zinc finger 1
chr10_+_24869982 0.216 ENSMUST00000092646.6
 Med23
mediator complex subunit 23
chr2_-_156111954 0.211 ENSMUST00000142960.2
ENSMUST00000136296.2
ENSMUST00000059647.5
ENSMUST00000109604.2
ENSMUST00000138068.1
ENSMUST00000128499.1
 Cpne1

Rbm12



copine I

RNA binding motif protein 12



chr5_+_121795034 0.197 ENSMUST00000162327.1
 Atxn2
ataxin 2
chr15_-_81104999 0.187 ENSMUST00000109579.2
 Mkl1
MKL (megakaryoblastic leukemia)/myocardin-like 1
chr5_+_89027959 0.184 ENSMUST00000130041.1
 Slc4a4
solute carrier family 4 (anion exchanger), member 4
chr11_-_50292302 0.182 ENSMUST00000059458.4
 Maml1
mastermind like 1 (Drosophila)
chr9_+_101074727 0.180 ENSMUST00000085177.3
 Msl2
male-specific lethal 2 homolog (Drosophila)
chr1_+_9848375 0.179 ENSMUST00000097826.4
 Sgk3
serum/glucocorticoid regulated kinase 3
chr13_+_40859768 0.177 ENSMUST00000110191.2
 Gcnt2
glucosaminyl (N-acetyl) transferase 2, I-branching enzyme
chr2_-_86347764 0.172 ENSMUST00000099894.2
 Olfr1055
olfactory receptor 1055
chr10_+_17796256 0.159 ENSMUST00000037964.6
 Txlnb
taxilin beta
chr14_-_121698417 0.150 ENSMUST00000040700.7
 Dock9
dedicator of cytokinesis 9
chr11_+_98937669 0.143 ENSMUST00000107475.2
ENSMUST00000068133.3
 Rara

retinoic acid receptor, alpha

chr5_+_145084100 0.143 ENSMUST00000124379.1
 Arpc1a
actin related protein 2/3 complex, subunit 1A
chr2_-_127247768 0.142 ENSMUST00000003759.4
 Ciao1
cytosolic iron-sulfur protein assembly 1
chr3_+_28805436 0.131 ENSMUST00000043867.5
 Rpl22l1
ribosomal protein L22 like 1
chr5_+_89028035 0.122 ENSMUST00000113216.2
ENSMUST00000134303.1
 Slc4a4

solute carrier family 4 (anion exchanger), member 4

chr7_+_83631959 0.118 ENSMUST00000075418.7
ENSMUST00000117410.1
 Stard5

StAR-related lipid transfer (START) domain containing 5

chr4_-_43030440 0.111 ENSMUST00000135660.1
 Stoml2
stomatin (Epb7.2)-like 2
chr7_-_73541738 0.086 ENSMUST00000169922.2
 Chd2
chromodomain helicase DNA binding protein 2
chr10_+_121365078 0.070 ENSMUST00000040344.6
 Gns
glucosamine (N-acetyl)-6-sulfatase
chr2_+_15055274 0.066 ENSMUST00000069870.3
 Arl5b
ADP-ribosylation factor-like 5B
chr5_-_87490869 0.060 ENSMUST00000147854.1
 Ugt2a1
UDP glucuronosyltransferase 2 family, polypeptide A1
chr10_+_115569986 0.058 ENSMUST00000173620.1
 A930009A15Rik
RIKEN cDNA A930009A15 gene
chr2_+_157279065 0.041 ENSMUST00000029171.5
 Rpn2
ribophorin II
chr2_+_157279026 0.032 ENSMUST00000116380.2
 Rpn2
ribophorin II
chr9_+_52047150 0.030 ENSMUST00000163153.1
 Rdx
radixin
chr8_-_83442648 0.018 ENSMUST00000167525.1
 Scoc
short coiled-coil protein
chrX_+_85574018 0.006 ENSMUST00000048250.3
ENSMUST00000137438.1
ENSMUST00000146063.1
 Tab3


TGF-beta activated kinase 1/MAP3K7 binding protein 3


chr5_+_145083830 0.003 ENSMUST00000031625.8
 Arpc1a
actin related protein 2/3 complex, subunit 1A
chr5_+_15516489 0.003 ENSMUST00000178227.1
 Gm21847
predicted gene, 21847
chr19_-_46969474 0.003 ENSMUST00000086961.7
 Nt5c2
5'-nucleotidase, cytosolic II

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:2000620 positive regulation of histone H4-K16 acetylation(GO:2000620)
0.2 0.5 GO:1904742 protein poly-ADP-ribosylation(GO:0070212) regulation of telomeric DNA binding(GO:1904742)
0.1 0.8 GO:0016080 synaptic vesicle targeting(GO:0016080)
0.1 2.4 GO:0035020 regulation of Rac protein signal transduction(GO:0035020)
0.1 3.1 GO:0010842 retina layer formation(GO:0010842)
0.1 0.5 GO:0070125 mitochondrial translational elongation(GO:0070125)
0.1 2.4 GO:0045663 positive regulation of myoblast differentiation(GO:0045663)
0.1 1.2 GO:0061162 establishment of monopolar cell polarity(GO:0061162)
0.1 0.3 GO:0032696 negative regulation of interleukin-13 production(GO:0032696) negative regulation of interleukin-10 secretion(GO:2001180)
0.1 0.5 GO:0060315 negative regulation of ryanodine-sensitive calcium-release channel activity(GO:0060315)
0.1 0.2 GO:2000409 positive regulation of T cell extravasation(GO:2000409)
0.1 1.0 GO:0050966 detection of mechanical stimulus involved in sensory perception of pain(GO:0050966)
0.1 0.2 GO:0003162 atrioventricular node development(GO:0003162)
0.1 0.2 GO:1903265 positive regulation of tumor necrosis factor-mediated signaling pathway(GO:1903265)
0.0 0.1 GO:0060010 Sertoli cell fate commitment(GO:0060010)
0.0 0.5 GO:2000270 negative regulation of fibroblast apoptotic process(GO:2000270)
0.0 0.2 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.0 0.2 GO:0010735 positive regulation of transcription via serum response element binding(GO:0010735)
0.0 0.1 GO:1990046 positive regulation of mitochondrial DNA replication(GO:0090297) regulation of cardiolipin metabolic process(GO:1900208) positive regulation of cardiolipin metabolic process(GO:1900210) stress-induced mitochondrial fusion(GO:1990046)
0.0 0.2 GO:0036438 maintenance of lens transparency(GO:0036438)
0.0 0.3 GO:0046015 regulation of transcription by glucose(GO:0046015)
0.0 0.6 GO:0006047 UDP-N-acetylglucosamine metabolic process(GO:0006047)
0.0 0.4 GO:0015693 magnesium ion transport(GO:0015693)
0.0 0.4 GO:0016226 iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.0 0.3 GO:0015701 bicarbonate transport(GO:0015701)
0.0 0.4 GO:0006879 cellular iron ion homeostasis(GO:0006879)
0.0 0.2 GO:0010603 regulation of cytoplasmic mRNA processing body assembly(GO:0010603)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0042584 chromaffin granule membrane(GO:0042584)
0.2 0.8 GO:0044316 cone cell pedicle(GO:0044316)
0.1 2.4 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.1 1.0 GO:0043083 synaptic cleft(GO:0043083)
0.1 0.4 GO:0097361 CIA complex(GO:0097361)
0.1 1.2 GO:0043196 varicosity(GO:0043196)
0.1 0.3 GO:0033553 rDNA heterochromatin(GO:0033553)
0.0 2.4 GO:0044295 axonal growth cone(GO:0044295)
0.0 0.2 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.0 0.2 GO:0072487 MSL complex(GO:0072487)
0.0 0.3 GO:0070688 MLL5-L complex(GO:0070688)
0.0 0.8 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0 0.1 GO:0036195 muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)
0.0 0.5 GO:0071339 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.2 GO:0005519 cytoskeletal regulatory protein binding(GO:0005519)
0.1 0.6 GO:0008761 UDP-N-acetylglucosamine 2-epimerase activity(GO:0008761)
0.1 1.0 GO:0031749 D2 dopamine receptor binding(GO:0031749)
0.1 0.3 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.1 0.8 GO:0005522 profilin binding(GO:0005522)
0.1 0.2 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.0 2.4 GO:0030971 receptor tyrosine kinase binding(GO:0030971)
0.0 0.1 GO:0032052 bile acid binding(GO:0032052)
0.0 0.1 GO:1901611 phosphatidylglycerol binding(GO:1901611) cardiolipin binding(GO:1901612)
0.0 0.7 GO:0030159 receptor signaling complex scaffold activity(GO:0030159)
0.0 0.2 GO:0004984 olfactory receptor activity(GO:0004984)
0.0 0.5 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 0.5 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 0.4 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 0.2 GO:0050692 DBD domain binding(GO:0050692)
0.0 0.5 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.0 0.5 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 0.1 GO:0035014 retinoic acid binding(GO:0001972) phosphatidylinositol 3-kinase regulator activity(GO:0035014)
0.0 0.4 GO:0042165 neurotransmitter binding(GO:0042165)
0.0 0.3 GO:0005035 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.0 0.2 GO:0043522 leucine zipper domain binding(GO:0043522)
0.0 0.1 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.0 0.2 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.0 0.2 GO:0017081 chloride channel regulator activity(GO:0017081)