Motif ID: Sox11

Z-value: 0.610


Transcription factors associated with Sox11:

Gene SymbolEntrez IDGene Name
Sox11 ENSMUSG00000063632.5 Sox11

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Sox11mm10_v2_chr12_-_27342696_273427260.696.2e-03Click!


Activity profile for motif Sox11.

activity profile for motif Sox11


Sorted Z-values histogram for motif Sox11

Sorted Z-values for motif Sox11



Network of associatons between targets according to the STRING database.



First level regulatory network of Sox11

PNG image of the network

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Top targets:


Showing 1 to 20 of 73 entries
PromoterScoreRefseqGene SymbolGene Name
chr9_-_16378231 3.096 ENSMUST00000082170.5
 Fat3
FAT tumor suppressor homolog 3 (Drosophila)
chr9_+_89909775 2.356 ENSMUST00000034912.4
ENSMUST00000034909.4
 Rasgrf1

RAS protein-specific guanine nucleotide-releasing factor 1

chr16_-_44558864 1.335 ENSMUST00000023370.4
 Boc
biregional cell adhesion molecule-related/down-regulated by oncogenes (Cdon) binding protein
chr13_-_99516537 1.245 ENSMUST00000064762.4
 Map1b
microtubule-associated protein 1B
chr16_-_44558879 1.094 ENSMUST00000114634.1
 Boc
biregional cell adhesion molecule-related/down-regulated by oncogenes (Cdon) binding protein
chr11_+_69364010 1.061 ENSMUST00000166700.1
 Gm17305
predicted gene, 17305
chr6_-_136173492 1.029 ENSMUST00000111905.1
 Grin2b
glutamate receptor, ionotropic, NMDA2B (epsilon 2)
chr2_+_154548888 0.965 ENSMUST00000045116.4
ENSMUST00000109709.3
 1700003F12Rik

RIKEN cDNA 1700003F12 gene

chr7_+_70388305 0.889 ENSMUST00000080024.5
 B130024G19Rik
RIKEN cDNA B130024G19 gene
chr15_+_76797628 0.839 ENSMUST00000165535.2
 Gm17271
predicted gene, 17271
chr5_+_14514918 0.828 ENSMUST00000030691.10
ENSMUST00000182407.1
 Pclo

piccolo (presynaptic cytomatrix protein)

chr11_-_69369377 0.792 ENSMUST00000092971.6
ENSMUST00000108661.1
 Chd3

chromodomain helicase DNA binding protein 3

chr10_+_119992916 0.696 ENSMUST00000105261.2
 Grip1
glutamate receptor interacting protein 1
chr5_-_131616599 0.672 ENSMUST00000161804.1
 Auts2
autism susceptibility candidate 2
chr4_-_97584612 0.661 ENSMUST00000107068.2
 E130114P18Rik
RIKEN cDNA E130114P18 gene
chr4_-_97584605 0.640 ENSMUST00000107067.1
 E130114P18Rik
RIKEN cDNA E130114P18 gene
chr16_+_8830093 0.631 ENSMUST00000023150.5
 1810013L24Rik
RIKEN cDNA 1810013L24 gene
chr16_-_50330987 0.610 ENSMUST00000114488.1
 Bbx
bobby sox homolog (Drosophila)
chr4_-_44072578 0.601 ENSMUST00000173383.1
 Gne
glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase
chr5_+_8046077 0.546 ENSMUST00000088786.4
 Sri
sorcin

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 27 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 3.1 GO:0010842 retina layer formation(GO:0010842)
0.1 2.4 GO:0035020 regulation of Rac protein signal transduction(GO:0035020)
0.1 2.4 GO:0045663 positive regulation of myoblast differentiation(GO:0045663)
0.1 1.2 GO:0061162 establishment of monopolar cell polarity(GO:0061162)
0.1 1.0 GO:0050966 detection of mechanical stimulus involved in sensory perception of pain(GO:0050966)
0.1 0.8 GO:0016080 synaptic vesicle targeting(GO:0016080)
0.2 0.7 GO:2000620 positive regulation of histone H4-K16 acetylation(GO:2000620)
0.0 0.6 GO:0006047 UDP-N-acetylglucosamine metabolic process(GO:0006047)
0.2 0.5 GO:1904742 protein poly-ADP-ribosylation(GO:0070212) regulation of telomeric DNA binding(GO:1904742)
0.1 0.5 GO:0070125 mitochondrial translational elongation(GO:0070125)
0.1 0.5 GO:0060315 negative regulation of ryanodine-sensitive calcium-release channel activity(GO:0060315)
0.0 0.5 GO:2000270 negative regulation of fibroblast apoptotic process(GO:2000270)
0.0 0.4 GO:0015693 magnesium ion transport(GO:0015693)
0.0 0.4 GO:0016226 iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.0 0.4 GO:0006879 cellular iron ion homeostasis(GO:0006879)
0.1 0.3 GO:0032696 negative regulation of interleukin-13 production(GO:0032696) negative regulation of interleukin-10 secretion(GO:2001180)
0.0 0.3 GO:0046015 regulation of transcription by glucose(GO:0046015)
0.0 0.3 GO:0015701 bicarbonate transport(GO:0015701)
0.1 0.2 GO:2000409 positive regulation of T cell extravasation(GO:2000409)
0.1 0.2 GO:0003162 atrioventricular node development(GO:0003162)

Gene overrepresentation in cellular_component category:

Showing 1 to 14 of 14 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 2.4 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 2.4 GO:0044295 axonal growth cone(GO:0044295)
0.1 1.2 GO:0043196 varicosity(GO:0043196)
0.1 1.0 GO:0043083 synaptic cleft(GO:0043083)
0.2 0.8 GO:0044316 cone cell pedicle(GO:0044316)
0.0 0.8 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.2 0.5 GO:0042584 chromaffin granule membrane(GO:0042584)
0.0 0.5 GO:0071339 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.1 0.4 GO:0097361 CIA complex(GO:0097361)
0.1 0.3 GO:0033553 rDNA heterochromatin(GO:0033553)
0.0 0.3 GO:0070688 MLL5-L complex(GO:0070688)
0.0 0.2 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.0 0.2 GO:0072487 MSL complex(GO:0072487)
0.0 0.1 GO:0036195 muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 24 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 2.4 GO:0030971 receptor tyrosine kinase binding(GO:0030971)
0.2 1.2 GO:0005519 cytoskeletal regulatory protein binding(GO:0005519)
0.1 1.0 GO:0031749 D2 dopamine receptor binding(GO:0031749)
0.1 0.8 GO:0005522 profilin binding(GO:0005522)
0.0 0.7 GO:0030159 receptor signaling complex scaffold activity(GO:0030159)
0.1 0.6 GO:0008761 UDP-N-acetylglucosamine 2-epimerase activity(GO:0008761)
0.0 0.5 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 0.5 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 0.5 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.0 0.5 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 0.4 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 0.4 GO:0042165 neurotransmitter binding(GO:0042165)
0.1 0.3 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.0 0.3 GO:0005035 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.1 0.2 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.0 0.2 GO:0004984 olfactory receptor activity(GO:0004984)
0.0 0.2 GO:0050692 DBD domain binding(GO:0050692)
0.0 0.2 GO:0043522 leucine zipper domain binding(GO:0043522)
0.0 0.2 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.0 0.2 GO:0017081 chloride channel regulator activity(GO:0017081)