Motif ID: Sox14

Z-value: 1.083


Transcription factors associated with Sox14:

Gene SymbolEntrez IDGene Name
Sox14 ENSMUSG00000053747.8 Sox14

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Sox14mm10_v2_chr9_-_99876147_998761930.107.3e-01Click!


Activity profile for motif Sox14.

activity profile for motif Sox14


Sorted Z-values histogram for motif Sox14

Sorted Z-values for motif Sox14



Network of associatons between targets according to the STRING database.



First level regulatory network of Sox14

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr4_+_102254739 3.984 ENSMUST00000106907.2
 Pde4b
phosphodiesterase 4B, cAMP specific
chr3_+_65109343 2.983 ENSMUST00000159525.1
ENSMUST00000049230.8
 Kcnab1

potassium voltage-gated channel, shaker-related subfamily, beta member 1

chr11_+_67586675 2.520 ENSMUST00000108680.1
 Gas7
growth arrest specific 7
chr4_-_6990774 2.487 ENSMUST00000039987.3
 Tox
thymocyte selection-associated high mobility group box
chr4_+_62965560 2.138 ENSMUST00000030043.6
ENSMUST00000107415.1
ENSMUST00000064814.5
 Zfp618


zinc finger protein 618


chr14_+_61138445 2.010 ENSMUST00000089394.3
ENSMUST00000119509.1
 Sacs

sacsin

chr13_-_58113592 1.987 ENSMUST00000160860.1
 Klhl3
kelch-like 3
chr18_-_43059418 1.955 ENSMUST00000025377.7
 Ppp2r2b
protein phosphatase 2 (formerly 2A), regulatory subunit B (PR 52), beta isoform
chr13_+_93304940 1.879 ENSMUST00000109497.1
ENSMUST00000109498.1
ENSMUST00000060490.4
ENSMUST00000109492.1
ENSMUST00000109496.1
ENSMUST00000109495.1
 Homer1





homer homolog 1 (Drosophila)





chr11_+_67586520 1.784 ENSMUST00000108682.2
 Gas7
growth arrest specific 7
chr7_+_96210107 1.710 ENSMUST00000138760.1
 Tenm4
teneurin transmembrane protein 4
chr6_-_99028251 1.705 ENSMUST00000177437.1
ENSMUST00000177229.1
ENSMUST00000113321.1
ENSMUST00000124058.1
 Foxp1



forkhead box P1



chr16_+_52031549 1.656 ENSMUST00000114471.1
 Cblb
Casitas B-lineage lymphoma b
chr6_-_82774448 1.653 ENSMUST00000000642.4
 Hk2
hexokinase 2
chr13_-_14523178 1.586 ENSMUST00000110516.2
 Hecw1
HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1
chr2_+_102706356 1.567 ENSMUST00000123759.1
ENSMUST00000111212.1
ENSMUST00000005220.4
 Slc1a2


solute carrier family 1 (glial high affinity glutamate transporter), member 2


chr2_-_102186322 1.535 ENSMUST00000111222.1
ENSMUST00000058790.5
 Ldlrad3

low density lipoprotein receptor class A domain containing 3

chr10_-_6980376 1.507 ENSMUST00000105617.1
 Ipcef1
interaction protein for cytohesin exchange factors 1
chr18_-_43393346 1.434 ENSMUST00000025379.7
 Dpysl3
dihydropyrimidinase-like 3
chr12_-_32061221 1.322 ENSMUST00000003079.5
ENSMUST00000036497.9
 Prkar2b

protein kinase, cAMP dependent regulatory, type II beta


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 109 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.3 4.0 GO:1901898 negative regulation of relaxation of muscle(GO:1901078) negative regulation of relaxation of cardiac muscle(GO:1901898)
0.3 3.1 GO:2001256 regulation of store-operated calcium entry(GO:2001256)
0.2 3.0 GO:1902260 negative regulation of delayed rectifier potassium channel activity(GO:1902260) negative regulation of voltage-gated potassium channel activity(GO:1903817)
0.0 2.8 GO:0030032 lamellipodium assembly(GO:0030032)
0.0 2.1 GO:0032410 negative regulation of transporter activity(GO:0032410)
0.0 2.1 GO:0051017 actin filament bundle assembly(GO:0051017)
0.7 2.0 GO:0003096 renal sodium ion transport(GO:0003096)
0.3 2.0 GO:0034047 regulation of protein phosphatase type 2A activity(GO:0034047)
0.6 1.7 GO:0002669 positive regulation of T cell anergy(GO:0002669) positive regulation of lymphocyte anergy(GO:0002913)
0.4 1.7 GO:0032289 central nervous system myelin formation(GO:0032289) cardiac cell fate specification(GO:0060912)
0.4 1.7 GO:0035795 negative regulation of mitochondrial membrane permeability(GO:0035795)
0.2 1.7 GO:0032625 interleukin-21 production(GO:0032625) interleukin-21 secretion(GO:0072619)
0.4 1.6 GO:0021812 neuronal-glial interaction involved in cerebral cortex radial glia guided migration(GO:0021812)
0.3 1.6 GO:0089711 L-glutamate transmembrane transport(GO:0089711)
0.0 1.5 GO:0070613 regulation of protein processing(GO:0070613)
0.0 1.4 GO:0051491 positive regulation of filopodium assembly(GO:0051491)
0.0 1.3 GO:0043666 regulation of phosphoprotein phosphatase activity(GO:0043666)
0.3 1.2 GO:1990743 protein sialylation(GO:1990743)
0.2 1.2 GO:0061092 involuntary skeletal muscle contraction(GO:0003011) regulation of phospholipid translocation(GO:0061091) positive regulation of phospholipid translocation(GO:0061092)
0.4 1.1 GO:0015772 disaccharide transport(GO:0015766) sucrose transport(GO:0015770) oligosaccharide transport(GO:0015772)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 40 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 4.8 GO:0005884 actin filament(GO:0005884)
0.2 4.0 GO:0000930 gamma-tubulin complex(GO:0000930)
0.1 3.1 GO:0043034 costamere(GO:0043034)
0.5 3.0 GO:1990635 proximal dendrite(GO:1990635)
0.0 2.3 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.1 2.0 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 2.0 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.3 1.7 GO:0008623 CHRAC(GO:0008623)
0.4 1.6 GO:0043259 laminin-1 complex(GO:0005606) laminin-10 complex(GO:0043259)
0.0 1.6 GO:0030673 axolemma(GO:0030673)
0.0 1.4 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.1 1.3 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 1.3 GO:0005801 cis-Golgi network(GO:0005801)
0.1 1.2 GO:0000138 Golgi trans cisterna(GO:0000138)
0.0 1.1 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.1 1.0 GO:0042382 paraspeckles(GO:0042382)
0.2 0.9 GO:0090537 CERF complex(GO:0090537)
0.1 0.9 GO:0032593 insulin-responsive compartment(GO:0032593)
0.0 0.9 GO:0009925 basal plasma membrane(GO:0009925)
0.1 0.8 GO:0070688 MLL5-L complex(GO:0070688)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 73 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 5.3 GO:0030552 cAMP binding(GO:0030552)
0.0 3.4 GO:0051015 actin filament binding(GO:0051015)
0.4 3.1 GO:0031802 type 5 metabotropic glutamate receptor binding(GO:0031802)
0.2 3.0 GO:0070402 NADPH binding(GO:0070402)
0.1 2.8 GO:0001540 beta-amyloid binding(GO:0001540)
0.1 2.2 GO:0051721 protein phosphatase 2A binding(GO:0051721)
0.1 2.0 GO:0008601 protein phosphatase type 2A regulator activity(GO:0008601)
0.1 2.0 GO:0050750 low-density lipoprotein particle receptor binding(GO:0050750)
0.1 1.8 GO:0001784 phosphotyrosine binding(GO:0001784)
0.3 1.7 GO:0008865 fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.0 1.7 GO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
0.4 1.6 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.2 1.6 GO:0043208 glycosphingolipid binding(GO:0043208)
0.4 1.4 GO:0035374 chondroitin sulfate binding(GO:0035374)
0.0 1.3 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.2 1.2 GO:0003835 beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835)
0.1 1.2 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.4 1.1 GO:0008515 sucrose:proton symporter activity(GO:0008506) sucrose transmembrane transporter activity(GO:0008515) disaccharide transmembrane transporter activity(GO:0015154) oligosaccharide transmembrane transporter activity(GO:0015157)
0.1 1.1 GO:0005540 hyaluronic acid binding(GO:0005540)
0.1 1.0 GO:0032184 SUMO polymer binding(GO:0032184)