Motif ID: Sox15

Z-value: 1.139


Transcription factors associated with Sox15:

Gene SymbolEntrez IDGene Name
Sox15 ENSMUSG00000041287.5 Sox15



Activity profile for motif Sox15.

activity profile for motif Sox15


Sorted Z-values histogram for motif Sox15

Sorted Z-values for motif Sox15



Network of associatons between targets according to the STRING database.



First level regulatory network of Sox15

PNG image of the network

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Top targets:


Showing 1 to 20 of 121 entries
PromoterScoreRefseqGene SymbolGene Name
chr12_-_119238794 4.660 ENSMUST00000026360.8
Itgb8
integrin beta 8
chr6_+_17491216 3.140 ENSMUST00000080469.5
Met
met proto-oncogene
chr6_+_17463927 2.912 ENSMUST00000115442.1
Met
met proto-oncogene
chr6_+_17463749 2.805 ENSMUST00000115443.1
Met
met proto-oncogene
chr6_+_17463826 2.380 ENSMUST00000140070.1
Met
met proto-oncogene
chr3_-_8964037 2.135 ENSMUST00000091354.5
ENSMUST00000094381.4
Tpd52

tumor protein D52

chr18_+_33464163 2.126 ENSMUST00000097634.3
Gm10549
predicted gene 10549
chr17_+_55445550 1.665 ENSMUST00000025000.3
St6gal2
beta galactoside alpha 2,6 sialyltransferase 2
chr3_+_31902666 1.642 ENSMUST00000119970.1
ENSMUST00000178668.1
Kcnmb2

potassium large conductance calcium-activated channel, subfamily M, beta member 2

chr14_-_79771305 1.572 ENSMUST00000039568.5
Pcdh8
protocadherin 8
chr6_+_125552948 1.391 ENSMUST00000112254.1
ENSMUST00000112253.1
ENSMUST00000001995.7
Vwf


Von Willebrand factor homolog


chr5_+_66968416 1.361 ENSMUST00000038188.7
Limch1
LIM and calponin homology domains 1
chr16_+_43508118 1.321 ENSMUST00000114690.1
Zbtb20
zinc finger and BTB domain containing 20
chr11_+_61653259 1.228 ENSMUST00000004959.2
Grap
GRB2-related adaptor protein
chr2_-_84425258 1.189 ENSMUST00000074262.2
Calcrl
calcitonin receptor-like
chr5_+_66968559 1.117 ENSMUST00000127184.1
Limch1
LIM and calponin homology domains 1
chr2_-_116067391 1.092 ENSMUST00000140185.1
2700033N17Rik
RIKEN cDNA 2700033N17 gene
chr11_+_88068242 1.076 ENSMUST00000018521.4
Vezf1
vascular endothelial zinc finger 1
chr11_+_97663366 1.060 ENSMUST00000044730.5
Mllt6
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 6
chr18_+_82554463 1.045 ENSMUST00000062446.7
ENSMUST00000102812.4
ENSMUST00000075372.5
ENSMUST00000080658.4
ENSMUST00000152071.1
ENSMUST00000114674.3
ENSMUST00000142850.1
ENSMUST00000133193.1
ENSMUST00000123251.1
ENSMUST00000153478.1
ENSMUST00000132369.1
Mbp










myelin basic protein











Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 49 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.2 11.1 GO:0060665 regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665)
0.2 4.7 GO:0001573 ganglioside metabolic process(GO:0001573)
0.0 2.5 GO:0031032 actomyosin structure organization(GO:0031032)
0.4 1.8 GO:0046684 response to pyrethroid(GO:0046684)
0.1 1.7 GO:0018279 N-acetylneuraminate metabolic process(GO:0006054) protein N-linked glycosylation via asparagine(GO:0018279)
0.0 1.4 GO:0030168 platelet activation(GO:0030168)
0.2 1.3 GO:0005513 detection of calcium ion(GO:0005513)
0.0 1.3 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.3 1.2 GO:0034285 response to sucrose(GO:0009744) response to disaccharide(GO:0034285)
0.0 1.1 GO:0001885 endothelial cell development(GO:0001885)
0.2 1.0 GO:0045578 negative regulation of B cell differentiation(GO:0045578)
0.0 1.0 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.3 0.9 GO:0030827 negative regulation of cGMP metabolic process(GO:0030824) negative regulation of cGMP biosynthetic process(GO:0030827) negative regulation of guanylate cyclase activity(GO:0031283)
0.1 0.9 GO:0061304 retinal blood vessel morphogenesis(GO:0061304)
0.1 0.9 GO:0051461 protein import into peroxisome matrix, docking(GO:0016560) regulation of corticotropin secretion(GO:0051459) positive regulation of corticotropin secretion(GO:0051461)
0.1 0.9 GO:0045200 establishment or maintenance of neuroblast polarity(GO:0045196) establishment of neuroblast polarity(GO:0045200)
0.2 0.8 GO:0072697 protein localization to cell cortex(GO:0072697)
0.0 0.8 GO:0045956 positive regulation of calcium ion-dependent exocytosis(GO:0045956)
0.1 0.7 GO:1900122 positive regulation of receptor binding(GO:1900122)
0.1 0.7 GO:1903608 protein localization to cytoplasmic stress granule(GO:1903608)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 23 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 11.4 GO:0009925 basal plasma membrane(GO:0009925)
0.2 4.7 GO:0008305 integrin complex(GO:0008305) protein complex involved in cell adhesion(GO:0098636)
0.0 2.0 GO:0005923 bicellular tight junction(GO:0005923)
0.1 1.8 GO:0034706 voltage-gated sodium channel complex(GO:0001518) sodium channel complex(GO:0034706)
0.3 1.4 GO:0033093 Weibel-Palade body(GO:0033093)
0.0 1.3 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.1 1.0 GO:0033269 internode region of axon(GO:0033269)
0.2 0.9 GO:0017071 intracellular cyclic nucleotide activated cation channel complex(GO:0017071)
0.2 0.9 GO:0005587 collagen type IV trimer(GO:0005587) network-forming collagen trimer(GO:0098642) collagen network(GO:0098645) basement membrane collagen trimer(GO:0098651)
0.1 0.9 GO:0044327 dendritic spine head(GO:0044327)
0.0 0.9 GO:0014704 intercalated disc(GO:0014704)
0.0 0.9 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.1 0.8 GO:0031045 dense core granule(GO:0031045)
0.2 0.7 GO:0097165 nuclear stress granule(GO:0097165)
0.2 0.6 GO:0035867 alphav-beta3 integrin-IGF-1-IGF1R complex(GO:0035867)
0.1 0.6 GO:0030485 smooth muscle contractile fiber(GO:0030485)
0.1 0.6 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.1 0.6 GO:0031528 anchored component of external side of plasma membrane(GO:0031362) microvillus membrane(GO:0031528)
0.1 0.5 GO:0070369 beta-catenin-TCF7L2 complex(GO:0070369)
0.0 0.4 GO:0005865 striated muscle thin filament(GO:0005865)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 36 entries
Log-likelihood per target Total log-likelihoodTermDescription
2.8 11.2 GO:0005008 hepatocyte growth factor-activated receptor activity(GO:0005008)
0.1 1.8 GO:0031402 sodium ion binding(GO:0031402)
0.3 1.7 GO:0003835 beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835)
0.2 1.4 GO:0019865 immunoglobulin binding(GO:0019865)
0.1 1.3 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.0 1.3 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.3 1.2 GO:0097642 calcitonin family receptor activity(GO:0097642)
0.3 1.0 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.2 0.9 GO:0005052 peroxisome matrix targeting signal-1 binding(GO:0005052)
0.1 0.9 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.1 0.9 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.0 0.9 GO:0032794 GTPase activating protein binding(GO:0032794)
0.0 0.9 GO:0051721 protein phosphatase 2A binding(GO:0051721)
0.0 0.9 GO:0017080 sodium channel regulator activity(GO:0017080)
0.0 0.8 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.1 0.7 GO:0070679 inositol 1,4,5 trisphosphate binding(GO:0070679)
0.0 0.7 GO:0017091 AU-rich element binding(GO:0017091)
0.0 0.7 GO:0017022 myosin binding(GO:0017022)
0.0 0.7 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.1 0.6 GO:0070699 type II activin receptor binding(GO:0070699)