Motif ID: Sox17

Z-value: 0.592


Transcription factors associated with Sox17:

Gene SymbolEntrez IDGene Name
Sox17 ENSMUSG00000025902.7 Sox17

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Sox17mm10_v2_chr1_-_4496363_4496389-0.612.2e-02Click!


Activity profile for motif Sox17.

activity profile for motif Sox17


Sorted Z-values histogram for motif Sox17

Sorted Z-values for motif Sox17



Network of associatons between targets according to the STRING database.



First level regulatory network of Sox17

PNG image of the network

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Top targets:


Showing 1 to 20 of 76 entries
PromoterScoreRefseqGene SymbolGene Name
chr6_-_144209471 3.054 ENSMUST00000038815.7
 Sox5
SRY-box containing gene 5
chr6_-_144209448 3.039 ENSMUST00000077160.5
 Sox5
SRY-box containing gene 5
chr6_-_144209558 2.927 ENSMUST00000111749.1
ENSMUST00000170367.2
 Sox5

SRY-box containing gene 5

chr2_-_57113053 2.273 ENSMUST00000112627.1
 Nr4a2
nuclear receptor subfamily 4, group A, member 2
chr11_-_110095937 1.666 ENSMUST00000106664.3
ENSMUST00000046223.7
ENSMUST00000106662.1
 Abca8a


ATP-binding cassette, sub-family A (ABC1), member 8a


chr14_+_68083853 1.397 ENSMUST00000022639.7
 Nefl
neurofilament, light polypeptide
chr15_+_74721193 1.238 ENSMUST00000070923.1
 Them6
thioesterase superfamily member 6
chr11_-_110095974 1.223 ENSMUST00000100287.2
 Abca8a
ATP-binding cassette, sub-family A (ABC1), member 8a
chr1_-_40085823 1.220 ENSMUST00000181756.1
 Gm16894
predicted gene, 16894
chr2_+_52857844 0.958 ENSMUST00000090952.4
ENSMUST00000049483.6
ENSMUST00000050719.6
 Fmnl2


formin-like 2


chr2_+_80617045 0.870 ENSMUST00000028384.4
 Dusp19
dual specificity phosphatase 19
chr11_-_11970540 0.802 ENSMUST00000109653.1
 Grb10
growth factor receptor bound protein 10
chr9_-_75597643 0.798 ENSMUST00000164100.1
 Tmod2
tropomodulin 2
chr13_+_54071815 0.767 ENSMUST00000021930.8
 Sfxn1
sideroflexin 1
chr15_+_85205949 0.766 ENSMUST00000057410.7
ENSMUST00000109432.3
 Fbln1

fibulin 1

chr7_-_98112618 0.744 ENSMUST00000153657.1
 Myo7a
myosin VIIA
chr2_+_102659213 0.678 ENSMUST00000111213.1
 Slc1a2
solute carrier family 1 (glial high affinity glutamate transporter), member 2
chr5_+_26817357 0.603 ENSMUST00000071500.6
 Dpp6
dipeptidylpeptidase 6
chr11_+_104282371 0.589 ENSMUST00000106988.1
ENSMUST00000106989.1
 Mapt

microtubule-associated protein tau

chr2_-_15049254 0.545 ENSMUST00000028034.8
ENSMUST00000114713.1
 Nsun6

NOL1/NOP2/Sun domain family member 6


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 33 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.1 9.0 GO:0060164 regulation of timing of neuron differentiation(GO:0060164)
0.0 2.9 GO:0006869 lipid transport(GO:0006869)
0.6 2.3 GO:0051866 general adaptation syndrome(GO:0051866)
0.5 1.4 GO:0045110 intermediate filament bundle assembly(GO:0045110)
0.0 1.0 GO:0030866 cortical actin cytoskeleton organization(GO:0030866)
0.1 0.9 GO:0043508 negative regulation of JUN kinase activity(GO:0043508)
0.3 0.8 GO:0006931 substrate-dependent cell migration, cell attachment to substrate(GO:0006931)
0.1 0.8 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.1 0.8 GO:0045719 negative regulation of glycogen biosynthetic process(GO:0045719) negative regulation of glycogen metabolic process(GO:0070874)
0.0 0.8 GO:0006826 iron ion transport(GO:0006826)
0.1 0.7 GO:0089711 L-glutamate transmembrane transport(GO:0089711)
0.1 0.7 GO:0048563 post-embryonic organ morphogenesis(GO:0048563)
0.0 0.6 GO:1900454 positive regulation of long term synaptic depression(GO:1900454)
0.0 0.6 GO:0090004 positive regulation of establishment of protein localization to plasma membrane(GO:0090004)
0.1 0.5 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.0 0.5 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.0 0.5 GO:0035025 positive regulation of Rho protein signal transduction(GO:0035025)
0.1 0.4 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.0 0.4 GO:0009186 deoxyribonucleoside diphosphate metabolic process(GO:0009186)
0.0 0.4 GO:0045086 positive regulation of interleukin-2 biosynthetic process(GO:0045086)

Gene overrepresentation in cellular_component category:

Showing 1 to 14 of 14 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 8.6 GO:0044798 nuclear transcription factor complex(GO:0044798)
0.5 1.4 GO:0033596 TSC1-TSC2 complex(GO:0033596)
0.0 1.0 GO:0001669 acrosomal vesicle(GO:0001669)
0.3 0.8 GO:0071953 fibrinogen complex(GO:0005577) elastic fiber(GO:0071953)
0.0 0.8 GO:0005865 striated muscle thin filament(GO:0005865)
0.1 0.7 GO:0002139 stereocilia coupling link(GO:0002139)
0.0 0.7 GO:0030673 axolemma(GO:0030673)
0.1 0.6 GO:0045298 tubulin complex(GO:0045298)
0.1 0.4 GO:0005971 ribonucleoside-diphosphate reductase complex(GO:0005971)
0.1 0.4 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.0 0.4 GO:0031464 Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.0 0.3 GO:0016580 Sin3 complex(GO:0016580)
0.1 0.2 GO:0044614 nuclear pore cytoplasmic filaments(GO:0044614)
0.0 0.1 GO:0071006 U2-type catalytic step 1 spliceosome(GO:0071006)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 24 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 9.0 GO:0046982 protein heterodimerization activity(GO:0046982)
0.0 2.9 GO:0042626 ATPase activity, coupled to transmembrane movement of substances(GO:0042626)
0.1 2.3 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.1 1.4 GO:0043274 phospholipase binding(GO:0043274)
0.0 1.2 GO:0017048 Rho GTPase binding(GO:0017048)
0.1 0.9 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.2 0.8 GO:0070051 fibrinogen binding(GO:0070051)
0.1 0.8 GO:0005523 tropomyosin binding(GO:0005523)
0.0 0.8 GO:0001784 phosphotyrosine binding(GO:0001784)
0.2 0.7 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.0 0.7 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.0 0.6 GO:0034185 apolipoprotein binding(GO:0034185)
0.0 0.6 GO:0015459 potassium channel regulator activity(GO:0015459)
0.1 0.5 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.0 0.5 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.1 0.4 GO:0005171 hepatocyte growth factor receptor binding(GO:0005171)
0.1 0.4 GO:0061731 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.0 0.4 GO:0016676 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.1 0.3 GO:0016206 catechol O-methyltransferase activity(GO:0016206)
0.0 0.2 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)