Motif ID: Sox4

Z-value: 0.697


Transcription factors associated with Sox4:

Gene SymbolEntrez IDGene Name
Sox4 ENSMUSG00000076431.4 Sox4

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Sox4mm10_v2_chr13_-_28953690_289537130.322.7e-01Click!


Activity profile for motif Sox4.

activity profile for motif Sox4


Sorted Z-values histogram for motif Sox4

Sorted Z-values for motif Sox4



Network of associatons between targets according to the STRING database.



First level regulatory network of Sox4

PNG image of the network

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Top targets:


Showing 1 to 20 of 115 entries
PromoterScoreRefseqGene SymbolGene Name
chr7_+_100493795 1.942 ENSMUST00000129324.1
 Ucp2
uncoupling protein 2 (mitochondrial, proton carrier)
chr1_+_153665274 1.861 ENSMUST00000152114.1
ENSMUST00000111812.1
 Rgs8

regulator of G-protein signaling 8

chr7_+_100494044 1.701 ENSMUST00000153287.1
 Ucp2
uncoupling protein 2 (mitochondrial, proton carrier)
chr7_+_45216671 1.430 ENSMUST00000134420.1
 Tead2
TEA domain family member 2
chr15_+_3270767 0.915 ENSMUST00000082424.4
ENSMUST00000159158.1
ENSMUST00000159216.1
ENSMUST00000160311.1
 Sepp1



selenoprotein P, plasma, 1



chr5_+_3928267 0.915 ENSMUST00000044492.8
 Akap9
A kinase (PRKA) anchor protein (yotiao) 9
chr17_-_70851189 0.795 ENSMUST00000059775.8
 Tgif1
TGFB-induced factor homeobox 1
chr1_+_135729147 0.772 ENSMUST00000027677.7
 Csrp1
cysteine and glycine-rich protein 1
chr9_-_32541589 0.731 ENSMUST00000016231.7
 Fli1
Friend leukemia integration 1
chr7_-_103853199 0.721 ENSMUST00000033229.3
 Hbb-y
hemoglobin Y, beta-like embryonic chain
chr12_-_54986363 0.707 ENSMUST00000173433.1
ENSMUST00000173803.1
 Baz1a
Gm20403
bromodomain adjacent to zinc finger domain 1A
predicted gene 20403
chr9_-_103480328 0.699 ENSMUST00000124310.2
 Bfsp2
beaded filament structural protein 2, phakinin
chrX_-_10117597 0.698 ENSMUST00000115543.2
ENSMUST00000044789.3
ENSMUST00000115544.2
 Srpx


sushi-repeat-containing protein


chr7_-_100514800 0.695 ENSMUST00000054923.7
 Dnajb13
DnaJ (Hsp40) related, subfamily B, member 13
chr11_-_115813621 0.695 ENSMUST00000041684.4
ENSMUST00000156812.1
 Caskin2

CASK-interacting protein 2

chr19_-_19001099 0.694 ENSMUST00000040153.8
ENSMUST00000112828.1
 Rorb

RAR-related orphan receptor beta

chr3_+_131110350 0.572 ENSMUST00000066849.6
ENSMUST00000106341.2
ENSMUST00000029611.7
 Lef1


lymphoid enhancer binding factor 1


chr18_-_43059418 0.563 ENSMUST00000025377.7
 Ppp2r2b
protein phosphatase 2 (formerly 2A), regulatory subunit B (PR 52), beta isoform
chr12_+_49385174 0.563 ENSMUST00000110746.1
 3110039M20Rik
RIKEN cDNA 3110039M20 gene
chr19_+_34922351 0.558 ENSMUST00000087341.5
 Kif20b
kinesin family member 20B

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 40 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.3 3.9 GO:0061179 negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179)
0.1 1.9 GO:0060159 regulation of dopamine receptor signaling pathway(GO:0060159)
0.1 1.4 GO:0048368 notochord development(GO:0030903) lateral mesoderm development(GO:0048368)
0.1 1.2 GO:0007194 negative regulation of adenylate cyclase activity(GO:0007194)
0.1 1.1 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.1 1.0 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.1 0.9 GO:0001887 selenium compound metabolic process(GO:0001887)
0.0 0.9 GO:0042632 cholesterol homeostasis(GO:0042632) sterol homeostasis(GO:0055092)
0.0 0.9 GO:0050852 T cell receptor signaling pathway(GO:0050852)
0.3 0.8 GO:0046671 negative regulation of retinal cell programmed cell death(GO:0046671)
0.0 0.8 GO:0035855 megakaryocyte development(GO:0035855)
0.2 0.7 GO:0060244 negative regulation of cell proliferation involved in contact inhibition(GO:0060244)
0.1 0.7 GO:0015671 oxygen transport(GO:0015671)
0.1 0.7 GO:0014834 skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration(GO:0014834)
0.1 0.7 GO:0046549 retinal cone cell development(GO:0046549)
0.0 0.7 GO:0070307 lens fiber cell development(GO:0070307)
0.2 0.6 GO:0032696 negative regulation of interleukin-13 production(GO:0032696) trachea submucosa development(GO:0061152) trachea gland development(GO:0061153) odontoblast differentiation(GO:0071895) regulation of estrogen receptor binding(GO:0071898) negative regulation of estrogen receptor binding(GO:0071899)
0.1 0.6 GO:1902410 mitotic cytokinetic process(GO:1902410)
0.1 0.6 GO:0034047 regulation of protein phosphatase type 2A activity(GO:0034047)
0.0 0.5 GO:0046697 decidualization(GO:0046697)

Gene overrepresentation in cellular_component category:

Showing 1 to 18 of 18 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 1.9 GO:0032809 neuronal cell body membrane(GO:0032809)
0.3 1.2 GO:0044307 dendritic branch(GO:0044307)
0.2 1.0 GO:0008623 CHRAC(GO:0008623)
0.2 0.9 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.1 0.7 GO:0005833 hemoglobin complex(GO:0005833)
0.1 0.6 GO:1990907 beta-catenin-TCF complex(GO:1990907)
0.1 0.6 GO:1990023 mitotic spindle midzone(GO:1990023)
0.0 0.6 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.5 GO:0045120 pronucleus(GO:0045120)
0.1 0.4 GO:0038045 large latent transforming growth factor-beta complex(GO:0038045)
0.0 0.4 GO:0036038 MKS complex(GO:0036038)
0.1 0.3 GO:0031680 G-protein beta/gamma-subunit complex(GO:0031680)
0.0 0.2 GO:0033185 dolichol-phosphate-mannose synthase complex(GO:0033185)
0.0 0.2 GO:0000124 SAGA complex(GO:0000124)
0.0 0.2 GO:0071004 U2-type prespliceosome(GO:0071004)
0.0 0.1 GO:0097543 ciliary inversin compartment(GO:0097543)
0.0 0.1 GO:0005971 ribonucleoside-diphosphate reductase complex(GO:0005971)
0.0 0.0 GO:0033193 Lsd1/2 complex(GO:0033193)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 29 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 4.3 GO:0003735 structural constituent of ribosome(GO:0003735)
0.0 1.9 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.0 1.4 GO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
0.1 1.2 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.1 1.1 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
0.0 1.0 GO:0070410 co-SMAD binding(GO:0070410)
0.1 0.9 GO:0008430 selenium binding(GO:0008430)
0.1 0.9 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.2 0.7 GO:0008502 melatonin receptor activity(GO:0008502)
0.2 0.7 GO:0031721 hemoglobin alpha binding(GO:0031721)
0.1 0.7 GO:0005212 structural constituent of eye lens(GO:0005212)
0.1 0.6 GO:0030284 estrogen receptor activity(GO:0030284)
0.0 0.6 GO:0008601 protein phosphatase type 2A regulator activity(GO:0008601)
0.0 0.6 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.0 0.6 GO:0000980 RNA polymerase II distal enhancer sequence-specific DNA binding(GO:0000980)
0.1 0.5 GO:0070878 primary miRNA binding(GO:0070878)
0.1 0.5 GO:0004921 interleukin-11 receptor activity(GO:0004921) interleukin-11 binding(GO:0019970)
0.1 0.4 GO:0050436 microfibril binding(GO:0050436)
0.0 0.4 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.0 0.4 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)