Motif ID: Sox4

Z-value: 0.697


Transcription factors associated with Sox4:

Gene SymbolEntrez IDGene Name
Sox4 ENSMUSG00000076431.4 Sox4

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Sox4mm10_v2_chr13_-_28953690_289537130.322.7e-01Click!


Activity profile for motif Sox4.

activity profile for motif Sox4


Sorted Z-values histogram for motif Sox4

Sorted Z-values for motif Sox4



Network of associatons between targets according to the STRING database.



First level regulatory network of Sox4

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr7_+_100493795 1.942 ENSMUST00000129324.1
 Ucp2
uncoupling protein 2 (mitochondrial, proton carrier)
chr1_+_153665274 1.861 ENSMUST00000152114.1
ENSMUST00000111812.1
 Rgs8

regulator of G-protein signaling 8

chr7_+_100494044 1.701 ENSMUST00000153287.1
 Ucp2
uncoupling protein 2 (mitochondrial, proton carrier)
chr7_+_45216671 1.430 ENSMUST00000134420.1
 Tead2
TEA domain family member 2
chr15_+_3270767 0.915 ENSMUST00000082424.4
ENSMUST00000159158.1
ENSMUST00000159216.1
ENSMUST00000160311.1
 Sepp1



selenoprotein P, plasma, 1



chr5_+_3928267 0.915 ENSMUST00000044492.8
 Akap9
A kinase (PRKA) anchor protein (yotiao) 9
chr17_-_70851189 0.795 ENSMUST00000059775.8
 Tgif1
TGFB-induced factor homeobox 1
chr1_+_135729147 0.772 ENSMUST00000027677.7
 Csrp1
cysteine and glycine-rich protein 1
chr9_-_32541589 0.731 ENSMUST00000016231.7
 Fli1
Friend leukemia integration 1
chr7_-_103853199 0.721 ENSMUST00000033229.3
 Hbb-y
hemoglobin Y, beta-like embryonic chain
chr12_-_54986363 0.707 ENSMUST00000173433.1
ENSMUST00000173803.1
 Baz1a
Gm20403
bromodomain adjacent to zinc finger domain 1A
predicted gene 20403
chr9_-_103480328 0.699 ENSMUST00000124310.2
 Bfsp2
beaded filament structural protein 2, phakinin
chrX_-_10117597 0.698 ENSMUST00000115543.2
ENSMUST00000044789.3
ENSMUST00000115544.2
 Srpx


sushi-repeat-containing protein


chr7_-_100514800 0.695 ENSMUST00000054923.7
 Dnajb13
DnaJ (Hsp40) related, subfamily B, member 13
chr11_-_115813621 0.695 ENSMUST00000041684.4
ENSMUST00000156812.1
 Caskin2

CASK-interacting protein 2

chr19_-_19001099 0.694 ENSMUST00000040153.8
ENSMUST00000112828.1
 Rorb

RAR-related orphan receptor beta

chr3_+_131110350 0.572 ENSMUST00000066849.6
ENSMUST00000106341.2
ENSMUST00000029611.7
 Lef1


lymphoid enhancer binding factor 1


chr18_-_43059418 0.563 ENSMUST00000025377.7
 Ppp2r2b
protein phosphatase 2 (formerly 2A), regulatory subunit B (PR 52), beta isoform
chr12_+_49385174 0.563 ENSMUST00000110746.1
 3110039M20Rik
RIKEN cDNA 3110039M20 gene
chr19_+_34922351 0.558 ENSMUST00000087341.5
 Kif20b
kinesin family member 20B
chr17_-_35704000 0.555 ENSMUST00000097333.3
ENSMUST00000003628.6
 Ddr1

discoidin domain receptor family, member 1

chr2_-_33942111 0.504 ENSMUST00000130988.1
ENSMUST00000127936.1
ENSMUST00000134271.1
 Gm13403


predicted gene 13403


chr1_+_165788681 0.502 ENSMUST00000161971.1
ENSMUST00000178336.1
ENSMUST00000005907.5
ENSMUST00000027849.4
 Cd247



CD247 antigen



chr2_-_180776900 0.487 ENSMUST00000108878.1
 Bhlhe23
basic helix-loop-helix family, member e23
chr6_-_47594967 0.485 ENSMUST00000081721.6
ENSMUST00000114618.1
ENSMUST00000114616.1
 Ezh2


enhancer of zeste homolog 2 (Drosophila)


chr7_+_99466004 0.484 ENSMUST00000037359.2
 Klhl35
kelch-like 35
chr17_-_35704574 0.456 ENSMUST00000117301.1
ENSMUST00000134995.1
 Ddr1

discoidin domain receptor family, member 1

chr13_-_97747399 0.454 ENSMUST00000144993.1
 5330416C01Rik
RIKEN cDNA 5330416C01 gene
chr4_+_41762309 0.453 ENSMUST00000108042.2
 Il11ra1
interleukin 11 receptor, alpha chain 1
chr3_+_135826075 0.443 ENSMUST00000029810.5
 Slc39a8
solute carrier family 39 (metal ion transporter), member 8
chr1_+_165788746 0.435 ENSMUST00000161559.2
 Cd247
CD247 antigen
chr5_+_75075464 0.422 ENSMUST00000160104.1
ENSMUST00000040477.3
 Gsx2

GS homeobox 2

chr17_+_75005523 0.392 ENSMUST00000001927.5
 Ltbp1
latent transforming growth factor beta binding protein 1
chr14_+_101840602 0.365 ENSMUST00000159314.1
 Lmo7
LIM domain only 7
chr2_-_180776749 0.359 ENSMUST00000061098.2
 Bhlhe23
basic helix-loop-helix family, member e23
chr18_-_62756275 0.351 ENSMUST00000067450.1
ENSMUST00000048109.5
 2700046A07Rik

RIKEN cDNA 2700046A07 gene

chr12_-_24252181 0.341 ENSMUST00000169148.1
 Gm9312
predicted gene 9312
chr8_-_11635745 0.328 ENSMUST00000033905.5
ENSMUST00000169782.1
 Ankrd10

ankyrin repeat domain 10

chr12_-_54986328 0.323 ENSMUST00000038926.6
 Baz1a
bromodomain adjacent to zinc finger domain 1A
chr11_+_101442440 0.323 ENSMUST00000107249.1
 Rpl27
ribosomal protein L27
chr11_+_69846374 0.317 ENSMUST00000108632.1
 Plscr3
phospholipid scramblase 3
chr8_+_108714644 0.315 ENSMUST00000043896.8
 Zfhx3
zinc finger homeobox 3
chr5_-_114380505 0.307 ENSMUST00000102581.4
 Kctd10
potassium channel tetramerisation domain containing 10
chr11_+_69846665 0.306 ENSMUST00000019605.2
 Plscr3
phospholipid scramblase 3
chr12_-_98577940 0.305 ENSMUST00000110113.1
 Kcnk10
potassium channel, subfamily K, member 10
chr5_+_3928033 0.301 ENSMUST00000143365.1
 Akap9
A kinase (PRKA) anchor protein (yotiao) 9
chr9_+_85842852 0.298 ENSMUST00000098500.3
 Tpbg
trophoblast glycoprotein
chr10_-_116473875 0.290 ENSMUST00000068233.4
 Kcnmb4
potassium large conductance calcium-activated channel, subfamily M, beta member 4
chr11_+_101442298 0.287 ENSMUST00000077856.6
 Rpl27
ribosomal protein L27
chr3_+_146500071 0.256 ENSMUST00000119130.1
 Gng5
guanine nucleotide binding protein (G protein), gamma 5
chr17_-_70853482 0.254 ENSMUST00000118283.1
 Tgif1
TGFB-induced factor homeobox 1
chr5_-_134456702 0.243 ENSMUST00000073161.5
ENSMUST00000171794.2
ENSMUST00000111245.2
ENSMUST00000100654.3
ENSMUST00000167084.2
ENSMUST00000100652.3
ENSMUST00000100650.3
ENSMUST00000074114.5
 Gtf2ird1







general transcription factor II I repeat domain-containing 1







chr16_-_91044473 0.241 ENSMUST00000118522.1
 Paxbp1
PAX3 and PAX7 binding protein 1
chr11_+_69846610 0.239 ENSMUST00000152566.1
ENSMUST00000108633.2
 Plscr3

phospholipid scramblase 3

chr1_+_59482133 0.231 ENSMUST00000114246.2
ENSMUST00000037105.6
 Fzd7

frizzled homolog 7 (Drosophila)

chr7_-_105787544 0.224 ENSMUST00000078482.5
ENSMUST00000154659.1
 Dchs1

dachsous 1 (Drosophila)

chr9_-_111057235 0.222 ENSMUST00000111888.1
 Ccrl2
chemokine (C-C motif) receptor-like 2
chr15_-_76656905 0.219 ENSMUST00000176274.1
 Cyhr1
cysteine and histidine rich 1
chr1_-_55027473 0.219 ENSMUST00000027127.7
 Sf3b1
splicing factor 3b, subunit 1
chr5_-_24445166 0.214 ENSMUST00000115043.1
ENSMUST00000115041.1
 Fastk

Fas-activated serine/threonine kinase

chr5_-_24445254 0.214 ENSMUST00000030800.6
 Fastk
Fas-activated serine/threonine kinase
chr15_+_44428073 0.210 ENSMUST00000060652.3
 Eny2
enhancer of yellow 2 homolog (Drosophila)
chr12_-_72236692 0.206 ENSMUST00000021497.9
ENSMUST00000137990.1
 Rtn1

reticulon 1

chr6_-_39557830 0.191 ENSMUST00000036877.3
ENSMUST00000154149.1
 Dennd2a

DENN/MADD domain containing 2A

chr8_-_4259257 0.189 ENSMUST00000053252.7
 Ctxn1
cortexin 1
chr4_+_129513581 0.188 ENSMUST00000062356.6
 Marcksl1
MARCKS-like 1
chr1_-_36557517 0.186 ENSMUST00000114990.1
ENSMUST00000128104.1
ENSMUST00000027295.4
 Sema4c


sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C


chrX_-_145505136 0.178 ENSMUST00000112835.1
 Amot
angiomotin
chr7_-_105787567 0.172 ENSMUST00000144189.1
 Dchs1
dachsous 1 (Drosophila)
chr12_-_79296266 0.170 ENSMUST00000021547.6
 Zfyve26
zinc finger, FYVE domain containing 26
chr10_+_80150448 0.167 ENSMUST00000153477.1
 Midn
midnolin
chr11_+_88068242 0.161 ENSMUST00000018521.4
 Vezf1
vascular endothelial zinc finger 1
chr2_+_32570858 0.155 ENSMUST00000140592.1
ENSMUST00000028151.6
 Dpm2

dolichol-phosphate (beta-D) mannosyltransferase 2

chr14_+_54936456 0.154 ENSMUST00000037814.6
 Cmtm5
CKLF-like MARVEL transmembrane domain containing 5
chr11_-_98625661 0.151 ENSMUST00000104933.1
 Gm12355
predicted gene 12355
chr14_+_27039001 0.141 ENSMUST00000035336.3
 Il17rd
interleukin 17 receptor D
chr10_-_116473418 0.133 ENSMUST00000087965.4
ENSMUST00000164271.1
 Kcnmb4

potassium large conductance calcium-activated channel, subfamily M, beta member 4

chr15_+_102296256 0.124 ENSMUST00000064924.4
 Espl1
extra spindle poles-like 1 (S. cerevisiae)
chr12_-_112674193 0.123 ENSMUST00000001780.3
 Akt1
thymoma viral proto-oncogene 1
chr7_+_19212521 0.117 ENSMUST00000060225.4
 Gpr4
G protein-coupled receptor 4
chr19_+_40831248 0.115 ENSMUST00000025983.6
ENSMUST00000120057.1
 Ccnj

cyclin J

chr9_+_104002546 0.111 ENSMUST00000035167.8
ENSMUST00000117054.1
 Nphp3

nephronophthisis 3 (adolescent)

chr16_-_90284412 0.111 ENSMUST00000039280.7
 Scaf4
SR-related CTD-associated factor 4
chr11_-_106160101 0.110 ENSMUST00000045923.3
 Limd2
LIM domain containing 2
chr1_+_178319130 0.102 ENSMUST00000027781.6
 Cox20
COX20 Cox2 chaperone
chr11_+_70432627 0.101 ENSMUST00000084954.6
ENSMUST00000108568.3
ENSMUST00000079056.2
ENSMUST00000102564.4
ENSMUST00000124943.1
ENSMUST00000150076.1
ENSMUST00000102563.1
 Arrb2






arrestin, beta 2






chr4_-_91399984 0.098 ENSMUST00000102799.3
 Elavl2
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 2 (Hu antigen B)
chr12_-_72408934 0.098 ENSMUST00000078505.7
 Rtn1
reticulon 1
chr2_-_26910569 0.098 ENSMUST00000015920.5
ENSMUST00000139815.1
ENSMUST00000102899.3
 Med22


mediator complex subunit 22


chr17_-_35697971 0.095 ENSMUST00000146472.1
 Ddr1
discoidin domain receptor family, member 1
chr3_+_89164790 0.092 ENSMUST00000121212.2
ENSMUST00000152205.1
ENSMUST00000090927.5
ENSMUST00000148265.1
ENSMUST00000121931.1
 Clk2




CDC-like kinase 2




chrX_-_145505175 0.088 ENSMUST00000143610.1
 Amot
angiomotin
chr5_-_114380459 0.086 ENSMUST00000001125.5
 Kctd10
potassium channel tetramerisation domain containing 10
chr14_+_101840501 0.081 ENSMUST00000159026.1
 Lmo7
LIM domain only 7
chr12_-_22623087 0.079 ENSMUST00000171036.1
 Gm17391
predicted gene, 17391
chr3_-_75956888 0.071 ENSMUST00000038563.7
ENSMUST00000167078.1
ENSMUST00000117242.1
 Golim4


golgi integral membrane protein 4


chr16_-_84835484 0.064 ENSMUST00000114191.1
 Atp5j
ATP synthase, H+ transporting, mitochondrial F0 complex, subunit F
chr5_-_131538687 0.060 ENSMUST00000161374.1
 Auts2
autism susceptibility candidate 2
chr11_-_106159902 0.058 ENSMUST00000064545.4
 Limd2
LIM domain containing 2
chr12_+_24708984 0.055 ENSMUST00000154588.1
 Rrm2
ribonucleotide reductase M2
chr12_+_8674224 0.052 ENSMUST00000111122.2
 Pum2
pumilio 2 (Drosophila)
chr16_-_84835557 0.052 ENSMUST00000138279.1
ENSMUST00000023608.7
 Atp5j

ATP synthase, H+ transporting, mitochondrial F0 complex, subunit F

chr3_-_95133989 0.050 ENSMUST00000172572.2
ENSMUST00000173462.2
 Scnm1

sodium channel modifier 1

chr17_+_37193889 0.049 ENSMUST00000038844.6
 Ubd
ubiquitin D
chr4_+_115057683 0.044 ENSMUST00000161601.1
 Tal1
T cell acute lymphocytic leukemia 1
chr13_+_117220584 0.042 ENSMUST00000022242.7
 Emb
embigin
chrX_+_73639414 0.039 ENSMUST00000019701.8
 Dusp9
dual specificity phosphatase 9
chr11_+_54314896 0.039 ENSMUST00000072178.4
ENSMUST00000101211.2
ENSMUST00000101213.2
 Acsl6


acyl-CoA synthetase long-chain family member 6


chr7_-_105752193 0.031 ENSMUST00000033184.4
 Tpp1
tripeptidyl peptidase I
chr11_+_22512088 0.029 ENSMUST00000059319.7
 Tmem17
transmembrane protein 17
chr2_-_168206875 0.018 ENSMUST00000057793.4
 Adnp
activity-dependent neuroprotective protein
chr16_-_90284300 0.015 ENSMUST00000163419.1
 Scaf4
SR-related CTD-associated factor 4
chr7_+_127233227 0.013 ENSMUST00000056232.6
 Zfp553
zinc finger protein 553
chr11_-_49187159 0.011 ENSMUST00000046522.6
 Btnl9
butyrophilin-like 9
chr14_+_64589802 0.001 ENSMUST00000180610.1
 A930011O12Rik
RIKEN cDNA A930011O12 gene

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 3.9 GO:0061179 negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179)
0.3 0.8 GO:0046671 negative regulation of retinal cell programmed cell death(GO:0046671)
0.2 0.7 GO:0060244 negative regulation of cell proliferation involved in contact inhibition(GO:0060244)
0.2 0.6 GO:0032696 negative regulation of interleukin-13 production(GO:0032696) trachea submucosa development(GO:0061152) trachea gland development(GO:0061153) odontoblast differentiation(GO:0071895) regulation of estrogen receptor binding(GO:0071898) negative regulation of estrogen receptor binding(GO:0071899)
0.1 0.7 GO:0015671 oxygen transport(GO:0015671)
0.1 1.9 GO:0060159 regulation of dopamine receptor signaling pathway(GO:0060159)
0.1 0.9 GO:0001887 selenium compound metabolic process(GO:0001887)
0.1 0.7 GO:0014834 skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration(GO:0014834)
0.1 0.7 GO:0046549 retinal cone cell development(GO:0046549)
0.1 0.3 GO:1904059 regulation of locomotor rhythm(GO:1904059)
0.1 0.4 GO:0072137 condensed mesenchymal cell proliferation(GO:0072137)
0.1 0.6 GO:1902410 mitotic cytokinetic process(GO:1902410)
0.1 1.1 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.1 1.2 GO:0007194 negative regulation of adenylate cyclase activity(GO:0007194)
0.1 0.6 GO:0034047 regulation of protein phosphatase type 2A activity(GO:0034047)
0.1 1.0 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.1 0.3 GO:0003365 establishment of cell polarity involved in ameboidal cell migration(GO:0003365)
0.1 1.4 GO:0048368 notochord development(GO:0030903) lateral mesoderm development(GO:0048368)
0.1 0.4 GO:0005513 detection of calcium ion(GO:0005513)
0.0 0.7 GO:0070307 lens fiber cell development(GO:0070307)
0.0 0.2 GO:0014886 transition between slow and fast fiber(GO:0014886)
0.0 0.4 GO:0070574 cadmium ion transport(GO:0015691) cadmium ion transmembrane transport(GO:0070574)
0.0 0.3 GO:0072513 positive regulation of secondary heart field cardioblast proliferation(GO:0072513)
0.0 0.1 GO:0072008 glomerular mesangial cell differentiation(GO:0072008) glomerular mesangial cell development(GO:0072144)
0.0 0.1 GO:0048496 maintenance of organ identity(GO:0048496)
0.0 0.5 GO:0046697 decidualization(GO:0046697)
0.0 0.8 GO:0035855 megakaryocyte development(GO:0035855)
0.0 0.3 GO:0030322 stabilization of membrane potential(GO:0030322)
0.0 0.4 GO:0048853 forebrain morphogenesis(GO:0048853)
0.0 0.2 GO:1903300 negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300)
0.0 0.2 GO:0014842 regulation of skeletal muscle satellite cell proliferation(GO:0014842)
0.0 0.1 GO:0034392 negative regulation of smooth muscle cell apoptotic process(GO:0034392)
0.0 0.1 GO:2000620 positive regulation of histone H4-K16 acetylation(GO:2000620)
0.0 0.2 GO:0019348 dolichol metabolic process(GO:0019348)
0.0 0.4 GO:0032967 positive regulation of collagen biosynthetic process(GO:0032967)
0.0 0.1 GO:0060709 glycogen cell differentiation involved in embryonic placenta development(GO:0060709)
0.0 0.9 GO:0042632 cholesterol homeostasis(GO:0042632) sterol homeostasis(GO:0055092)
0.0 0.1 GO:1901970 positive regulation of mitotic sister chromatid separation(GO:1901970)
0.0 0.9 GO:0050852 T cell receptor signaling pathway(GO:0050852)
0.0 0.1 GO:0045721 negative regulation of gluconeogenesis(GO:0045721)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.2 GO:0044307 dendritic branch(GO:0044307)
0.2 0.9 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.2 1.0 GO:0008623 CHRAC(GO:0008623)
0.1 0.4 GO:0038045 large latent transforming growth factor-beta complex(GO:0038045)
0.1 0.7 GO:0005833 hemoglobin complex(GO:0005833)
0.1 0.3 GO:0031680 G-protein beta/gamma-subunit complex(GO:0031680)
0.1 0.6 GO:1990907 beta-catenin-TCF complex(GO:1990907)
0.1 0.6 GO:1990023 mitotic spindle midzone(GO:1990023)
0.0 1.9 GO:0032809 neuronal cell body membrane(GO:0032809)
0.0 0.2 GO:0033185 dolichol-phosphate-mannose synthase complex(GO:0033185)
0.0 0.1 GO:0097543 ciliary inversin compartment(GO:0097543)
0.0 0.6 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.4 GO:0036038 MKS complex(GO:0036038)
0.0 0.5 GO:0045120 pronucleus(GO:0045120)
0.0 0.2 GO:0000124 SAGA complex(GO:0000124)
0.0 0.0 GO:0033193 Lsd1/2 complex(GO:0033193)
0.0 0.2 GO:0071004 U2-type prespliceosome(GO:0071004)
0.0 0.1 GO:0005971 ribonucleoside-diphosphate reductase complex(GO:0005971)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0008502 melatonin receptor activity(GO:0008502)
0.2 0.7 GO:0031721 hemoglobin alpha binding(GO:0031721)
0.1 1.1 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
0.1 0.5 GO:0070878 primary miRNA binding(GO:0070878)
0.1 0.5 GO:0004921 interleukin-11 receptor activity(GO:0004921) interleukin-11 binding(GO:0019970)
0.1 0.4 GO:0050436 microfibril binding(GO:0050436)
0.1 0.6 GO:0030284 estrogen receptor activity(GO:0030284)
0.1 0.3 GO:0043532 angiostatin binding(GO:0043532)
0.1 0.7 GO:0005212 structural constituent of eye lens(GO:0005212)
0.1 0.2 GO:0016493 C-C chemokine receptor activity(GO:0016493)
0.1 0.9 GO:0008430 selenium binding(GO:0008430)
0.1 1.2 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.1 0.9 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.0 1.0 GO:0070410 co-SMAD binding(GO:0070410)
0.0 0.1 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.0 1.9 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.0 0.6 GO:0008601 protein phosphatase type 2A regulator activity(GO:0008601)
0.0 0.6 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.0 0.1 GO:0031826 type 2A serotonin receptor binding(GO:0031826)
0.0 0.2 GO:0004582 dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582)
0.0 0.4 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.0 0.3 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.0 4.3 GO:0003735 structural constituent of ribosome(GO:0003735)
0.0 0.4 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.4 GO:0042805 actinin binding(GO:0042805)
0.0 1.4 GO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
0.0 0.6 GO:0000980 RNA polymerase II distal enhancer sequence-specific DNA binding(GO:0000980)
0.0 0.1 GO:0061731 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.0 0.2 GO:0042813 Wnt-activated receptor activity(GO:0042813)