Motif ID: Sox5_Sry

Z-value: 1.749

Transcription factors associated with Sox5_Sry:

Gene SymbolEntrez IDGene Name
Sox5 ENSMUSG00000041540.10 Sox5
Sry ENSMUSG00000069036.3 Sry

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Sox5mm10_v2_chr6_-_143947092_1439471110.832.7e-04Click!





Network of associatons between targets according to the STRING database.



First level regulatory network of Sox5_Sry

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr6_-_144209558 7.286 ENSMUST00000111749.1
ENSMUST00000170367.2
Sox5

SRY-box containing gene 5

chr1_+_34005872 5.120 ENSMUST00000182296.1
Dst
dystonin
chr2_-_57124003 4.875 ENSMUST00000112629.1
Nr4a2
nuclear receptor subfamily 4, group A, member 2
chr10_-_45470201 4.779 ENSMUST00000079390.6
Lin28b
lin-28 homolog B (C. elegans)
chr4_-_82505707 4.509 ENSMUST00000107248.1
ENSMUST00000107247.1
Nfib

nuclear factor I/B

chr2_-_6722187 4.376 ENSMUST00000182657.1
Celf2
CUGBP, Elav-like family member 2
chr9_+_26733845 4.358 ENSMUST00000115269.2
B3gat1
beta-1,3-glucuronyltransferase 1 (glucuronosyltransferase P)
chr1_+_143640664 4.313 ENSMUST00000038252.2
B3galt2
UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 2
chr19_-_41206774 4.290 ENSMUST00000025986.7
ENSMUST00000169941.1
Tll2

tolloid-like 2

chr13_-_56252163 4.264 ENSMUST00000058475.4
Neurog1
neurogenin 1
chr9_+_26733728 3.955 ENSMUST00000160899.1
ENSMUST00000161431.1
ENSMUST00000159799.1
B3gat1


beta-1,3-glucuronyltransferase 1 (glucuronosyltransferase P)


chr7_+_75848338 3.827 ENSMUST00000092073.5
ENSMUST00000171155.2
Klhl25

kelch-like 25

chr6_+_15185456 3.779 ENSMUST00000115472.1
ENSMUST00000115474.1
ENSMUST00000031545.7
ENSMUST00000137628.1
Foxp2



forkhead box P2



chr10_+_69706326 3.423 ENSMUST00000182992.1
Ank3
ankyrin 3, epithelial
chr4_-_97584612 3.420 ENSMUST00000107068.2
E130114P18Rik
RIKEN cDNA E130114P18 gene
chr11_+_94044111 3.237 ENSMUST00000132079.1
Spag9
sperm associated antigen 9
chr16_-_44558879 3.112 ENSMUST00000114634.1
Boc
biregional cell adhesion molecule-related/down-regulated by oncogenes (Cdon) binding protein
chr16_-_44558864 3.061 ENSMUST00000023370.4
Boc
biregional cell adhesion molecule-related/down-regulated by oncogenes (Cdon) binding protein
chr4_-_97584605 3.049 ENSMUST00000107067.1
E130114P18Rik
RIKEN cDNA E130114P18 gene
chr4_-_82505274 2.915 ENSMUST00000050872.8
ENSMUST00000064770.2
Nfib

nuclear factor I/B


Gene overrepresentation in biological_process category:

Showing 1 to 20 of 155 entries
Log-likelihood per target Total log-likelihoodTermDescription
3.1 12.5 GO:2000795 negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
1.0 10.9 GO:0010650 positive regulation of cell communication by electrical coupling(GO:0010650) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
1.1 9.0 GO:0090074 negative regulation of protein homodimerization activity(GO:0090074)
0.9 7.3 GO:0060164 regulation of timing of neuron differentiation(GO:0060164)
0.4 7.2 GO:0050650 chondroitin sulfate proteoglycan biosynthetic process(GO:0050650)
0.2 6.5 GO:0006376 mRNA splice site selection(GO:0006376)
0.2 5.7 GO:0045663 positive regulation of myoblast differentiation(GO:0045663)
0.2 5.1 GO:0008090 retrograde axonal transport(GO:0008090)
1.2 4.9 GO:0051866 general adaptation syndrome(GO:0051866)
0.5 4.5 GO:0010587 miRNA catabolic process(GO:0010587)
0.9 4.3 GO:0048631 regulation of skeletal muscle tissue growth(GO:0048631)
0.6 4.3 GO:0031536 positive regulation of exit from mitosis(GO:0031536)
0.3 4.3 GO:0009312 oligosaccharide biosynthetic process(GO:0009312)
0.4 3.4 GO:0035881 amacrine cell differentiation(GO:0035881)
0.2 3.3 GO:0097094 craniofacial suture morphogenesis(GO:0097094)
1.0 3.0 GO:0001928 regulation of exocyst assembly(GO:0001928)
0.1 2.8 GO:0010971 positive regulation of G2/M transition of mitotic cell cycle(GO:0010971)
0.4 2.7 GO:0034047 regulation of protein phosphatase type 2A activity(GO:0034047)
0.0 2.7 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.8 2.5 GO:0007290 spermatid nucleus elongation(GO:0007290)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 63 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.6 12.5 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.5 10.9 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.0 8.9 GO:0005815 microtubule organizing center(GO:0005815)
0.1 7.4 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.1 6.2 GO:0044295 axonal growth cone(GO:0044295)
1.3 5.1 GO:0031673 H zone(GO:0031673)
0.0 4.4 GO:0044798 nuclear transcription factor complex(GO:0044798)
0.0 3.8 GO:0043204 perikaryon(GO:0043204)
0.1 2.8 GO:0071565 nBAF complex(GO:0071565)
0.1 2.7 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 2.7 GO:0043198 dendritic shaft(GO:0043198)
0.2 2.4 GO:0070852 cell body fiber(GO:0070852)
0.1 2.0 GO:0031430 M band(GO:0031430)
0.1 2.0 GO:0032809 neuronal cell body membrane(GO:0032809)
0.0 2.0 GO:0016363 nuclear matrix(GO:0016363)
0.1 1.9 GO:0042788 polysomal ribosome(GO:0042788)
0.0 1.9 GO:0030426 growth cone(GO:0030426)
0.0 1.8 GO:1990391 DNA repair complex(GO:1990391)
0.0 1.5 GO:0016459 myosin complex(GO:0016459)
0.0 1.4 GO:0048471 perinuclear region of cytoplasm(GO:0048471)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 98 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.4 12.9 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
1.6 12.6 GO:0008499 UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity(GO:0008499)
0.3 12.2 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.7 7.9 GO:0048273 mitogen-activated protein kinase p38 binding(GO:0048273)
0.1 5.7 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 5.0 GO:0008017 microtubule binding(GO:0008017)
0.5 4.9 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.1 4.5 GO:0070888 E-box binding(GO:0070888)
0.1 3.9 GO:0043015 gamma-tubulin binding(GO:0043015)
0.2 3.8 GO:0030275 LRR domain binding(GO:0030275)
0.1 3.2 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.1 3.2 GO:0018602 sulfonate dioxygenase activity(GO:0000907) 2,4-dichlorophenoxyacetate alpha-ketoglutarate dioxygenase activity(GO:0018602) hypophosphite dioxygenase activity(GO:0034792) gibberellin 2-beta-dioxygenase activity(GO:0045543) C-19 gibberellin 2-beta-dioxygenase activity(GO:0052634) C-20 gibberellin 2-beta-dioxygenase activity(GO:0052635)
0.0 3.2 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.2 2.7 GO:0008601 protein phosphatase type 2A regulator activity(GO:0008601)
0.1 2.7 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.0 2.6 GO:0030165 PDZ domain binding(GO:0030165)
0.1 2.3 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.3 2.2 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.7 2.0 GO:0008502 melatonin receptor activity(GO:0008502)
0.1 1.9 GO:0032452 histone demethylase activity(GO:0032452)