Motif ID: Sp1

Z-value: 0.813


Transcription factors associated with Sp1:

Gene SymbolEntrez IDGene Name
Sp1 ENSMUSG00000001280.6 Sp1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Sp1mm10_v2_chr15_+_102407144_102407269-0.621.9e-02Click!


Activity profile for motif Sp1.

activity profile for motif Sp1


Sorted Z-values histogram for motif Sp1

Sorted Z-values for motif Sp1



Network of associatons between targets according to the STRING database.



First level regulatory network of Sp1

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr11_+_119942763 1.174 ENSMUST00000026436.3
ENSMUST00000106231.1
ENSMUST00000075180.5
ENSMUST00000103021.3
ENSMUST00000106233.1
 Baiap2




brain-specific angiogenesis inhibitor 1-associated protein 2




chr4_+_125490688 1.101 ENSMUST00000030676.7
 Grik3
glutamate receptor, ionotropic, kainate 3
chr12_+_112146187 1.063 ENSMUST00000128402.2
 Kif26a
kinesin family member 26A
chr8_-_90908415 0.946 ENSMUST00000098517.1
 Gm6658
predicted gene 6658
chr13_-_56252163 0.935 ENSMUST00000058475.4
 Neurog1
neurogenin 1
chr8_-_84067283 0.834 ENSMUST00000071067.3
 C330011M18Rik
RIKEN cDNA C330011M18 gene
chr15_-_32244632 0.820 ENSMUST00000181536.1
 0610007N19Rik
RIKEN cDNA 0610007N19
chr4_+_47353283 0.798 ENSMUST00000044234.7
 Tgfbr1
transforming growth factor, beta receptor I
chr15_-_76521902 0.766 ENSMUST00000164703.1
ENSMUST00000096365.3
 Scrt1

scratch homolog 1, zinc finger protein (Drosophila)

chr13_+_104109752 0.733 ENSMUST00000160322.1
ENSMUST00000159574.1
 Sgtb

small glutamine-rich tetratricopeptide repeat (TPR)-containing, beta

chr10_-_127620922 0.723 ENSMUST00000118455.1
 Lrp1
low density lipoprotein receptor-related protein 1
chr7_+_123982799 0.723 ENSMUST00000106437.1
 Hs3st4
heparan sulfate (glucosamine) 3-O-sulfotransferase 4
chr4_-_151996113 0.721 ENSMUST00000055688.9
 Phf13
PHD finger protein 13
chr6_+_58831456 0.707 ENSMUST00000141600.1
ENSMUST00000122981.1
 Herc3

hect domain and RLD 3

chr3_+_121953213 0.707 ENSMUST00000037958.7
ENSMUST00000128366.1
 Arhgap29

Rho GTPase activating protein 29

chrX_-_52165252 0.707 ENSMUST00000033450.2
 Gpc4
glypican 4
chr4_-_133753611 0.702 ENSMUST00000145664.2
ENSMUST00000105897.3
 Arid1a

AT rich interactive domain 1A (SWI-like)

chr18_-_38211957 0.691 ENSMUST00000159405.1
ENSMUST00000160721.1
 Pcdh1

protocadherin 1

chr3_-_8667033 0.681 ENSMUST00000042412.3
 Hey1
hairy/enhancer-of-split related with YRPW motif 1
chr18_-_24709348 0.660 ENSMUST00000067987.1
 Gm9955
predicted gene 9955

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 937 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 2.4 GO:0009247 glycolipid biosynthetic process(GO:0009247)
0.0 2.4 GO:1903955 positive regulation of protein targeting to mitochondrion(GO:1903955)
0.1 1.8 GO:0002076 osteoblast development(GO:0002076)
0.1 1.7 GO:0007252 I-kappaB phosphorylation(GO:0007252)
0.1 1.6 GO:0007216 G-protein coupled glutamate receptor signaling pathway(GO:0007216)
0.1 1.6 GO:0010971 positive regulation of G2/M transition of mitotic cell cycle(GO:0010971)
0.0 1.6 GO:0042787 protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0042787)
0.3 1.5 GO:0060017 parathyroid gland development(GO:0060017)
0.3 1.5 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.1 1.5 GO:0007020 microtubule nucleation(GO:0007020)
0.3 1.4 GO:2000587 regulation of platelet-derived growth factor receptor-beta signaling pathway(GO:2000586) negative regulation of platelet-derived growth factor receptor-beta signaling pathway(GO:2000587)
0.1 1.4 GO:0051764 actin crosslink formation(GO:0051764)
0.1 1.4 GO:0016188 synaptic vesicle maturation(GO:0016188)
0.1 1.4 GO:0099517 anterograde synaptic vesicle transport(GO:0048490) synaptic vesicle cytoskeletal transport(GO:0099514) synaptic vesicle transport along microtubule(GO:0099517)
0.1 1.4 GO:0050650 chondroitin sulfate proteoglycan biosynthetic process(GO:0050650)
0.4 1.3 GO:0060489 establishment of body hair or bristle planar orientation(GO:0048104) establishment of body hair planar orientation(GO:0048105) orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060488) planar dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060489) lateral sprouting involved in lung morphogenesis(GO:0060490)
0.1 1.3 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.2 1.2 GO:0001842 neural fold formation(GO:0001842)
0.1 1.2 GO:0035025 positive regulation of Rho protein signal transduction(GO:0035025)
0.4 1.1 GO:0015772 disaccharide transport(GO:0015766) sucrose transport(GO:0015770) oligosaccharide transport(GO:0015772)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 321 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 7.4 GO:0014069 postsynaptic density(GO:0014069) postsynaptic specialization(GO:0099572)
0.1 2.5 GO:0071565 nBAF complex(GO:0071565)
0.1 2.3 GO:0030914 STAGA complex(GO:0030914)
0.0 1.9 GO:0055037 recycling endosome(GO:0055037)
0.1 1.8 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.0 1.8 GO:0005643 nuclear pore(GO:0005643)
0.0 1.6 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.1 1.5 GO:0008385 IkappaB kinase complex(GO:0008385)
0.0 1.5 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 1.5 GO:0005905 clathrin-coated pit(GO:0005905)
0.0 1.4 GO:0055038 recycling endosome membrane(GO:0055038)
0.0 1.4 GO:0097440 apical dendrite(GO:0097440)
0.0 1.4 GO:1990391 DNA repair complex(GO:1990391)
0.0 1.4 GO:0043204 perikaryon(GO:0043204)
0.1 1.3 GO:0000145 exocyst(GO:0000145)
0.1 1.3 GO:0070822 Sin3-type complex(GO:0070822)
0.0 1.3 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.0 1.2 GO:0008180 COP9 signalosome(GO:0008180)
0.4 1.1 GO:0048179 activin receptor complex(GO:0048179)
0.1 1.1 GO:1904115 axon cytoplasm(GO:1904115)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 542 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 5.7 GO:0004842 ubiquitin-protein transferase activity(GO:0004842)
0.0 2.4 GO:0030165 PDZ domain binding(GO:0030165)
0.0 2.3 GO:0070491 repressing transcription factor binding(GO:0070491)
0.1 2.2 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.1 2.0 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.1 1.8 GO:0034483 heparan sulfate sulfotransferase activity(GO:0034483)
0.1 1.7 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.1 1.6 GO:0034185 apolipoprotein binding(GO:0034185)
0.0 1.6 GO:0048487 beta-tubulin binding(GO:0048487)
0.3 1.5 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.1 1.5 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 1.5 GO:0019210 protein kinase inhibitor activity(GO:0004860) kinase inhibitor activity(GO:0019210)
0.1 1.4 GO:1990715 mRNA CDS binding(GO:1990715)
0.3 1.3 GO:0001640 adenylate cyclase inhibiting G-protein coupled glutamate receptor activity(GO:0001640)
0.2 1.3 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.2 1.3 GO:0031811 G-protein coupled nucleotide receptor binding(GO:0031811) P2Y1 nucleotide receptor binding(GO:0031812)
0.1 1.3 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.1 1.3 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.1 1.3 GO:0050321 tau-protein kinase activity(GO:0050321)
0.0 1.3 GO:0019894 kinesin binding(GO:0019894)