Motif ID: Sp2

Z-value: 0.851


Transcription factors associated with Sp2:

Gene SymbolEntrez IDGene Name
Sp2 ENSMUSG00000018678.6 Sp2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Sp2mm10_v2_chr11_-_96968655_96968673-0.293.1e-01Click!


Activity profile for motif Sp2.

activity profile for motif Sp2


Sorted Z-values histogram for motif Sp2

Sorted Z-values for motif Sp2



Network of associatons between targets according to the STRING database.



First level regulatory network of Sp2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr3_+_87948666 0.745 ENSMUST00000005019.5
 Crabp2
cellular retinoic acid binding protein II
chr14_+_54640952 0.693 ENSMUST00000169818.2
 Gm17606
predicted gene, 17606
chr4_+_3938888 0.687 ENSMUST00000121110.1
ENSMUST00000108386.1
ENSMUST00000149544.1
 Chchd7


coiled-coil-helix-coiled-coil-helix domain containing 7


chr4_+_3938904 0.678 ENSMUST00000120732.1
ENSMUST00000041122.4
ENSMUST00000121651.1
ENSMUST00000121210.1
ENSMUST00000119307.1
ENSMUST00000123769.1
 Chchd7





coiled-coil-helix-coiled-coil-helix domain containing 7





chr7_-_45061706 0.665 ENSMUST00000107832.1
 Prrg2
proline-rich Gla (G-carboxyglutamic acid) polypeptide 2
chr2_-_84775388 0.661 ENSMUST00000023994.3
 Serping1
serine (or cysteine) peptidase inhibitor, clade G, member 1
chr19_-_5424759 0.653 ENSMUST00000148219.2
 Drap1
Dr1 associated protein 1 (negative cofactor 2 alpha)
chr10_+_80167778 0.646 ENSMUST00000105365.2
ENSMUST00000054666.6
 Cirbp

cold inducible RNA binding protein

chr13_-_29984219 0.643 ENSMUST00000146092.1
 E2f3
E2F transcription factor 3
chr7_+_19508712 0.616 ENSMUST00000002112.8
ENSMUST00000108455.1
 Trappc6a

trafficking protein particle complex 6A

chr2_+_121449362 0.608 ENSMUST00000110615.1
ENSMUST00000099475.5
 Serf2

small EDRK-rich factor 2

chr11_+_101468164 0.607 ENSMUST00000001347.6
 Rnd2
Rho family GTPase 2
chr12_+_112644828 0.605 ENSMUST00000021728.4
ENSMUST00000109755.3
 Siva1

SIVA1, apoptosis-inducing factor

chr11_+_5861886 0.604 ENSMUST00000102923.3
 Aebp1
AE binding protein 1
chr4_-_25800083 0.602 ENSMUST00000084770.4
 Fut9
fucosyltransferase 9
chr7_-_110061319 0.581 ENSMUST00000098110.2
 AA474408
expressed sequence AA474408
chr2_-_84775420 0.574 ENSMUST00000111641.1
 Serping1
serine (or cysteine) peptidase inhibitor, clade G, member 1
chr7_-_142657466 0.566 ENSMUST00000097936.2
ENSMUST00000000033.5
 Igf2

insulin-like growth factor 2

chr19_+_6057925 0.565 ENSMUST00000179142.1
 Fau
Finkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV) ubiquitously expressed (fox derived)
chrX_-_37085402 0.551 ENSMUST00000115231.3
 Rpl39
ribosomal protein L39

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 144 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 1.6 GO:0002227 innate immune response in mucosa(GO:0002227)
0.4 1.2 GO:0001869 regulation of complement activation, lectin pathway(GO:0001868) negative regulation of complement activation, lectin pathway(GO:0001869)
0.1 1.2 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
0.1 0.8 GO:1904936 cerebral cortex GABAergic interneuron migration(GO:0021853) interneuron migration(GO:1904936)
0.1 0.8 GO:0033280 response to vitamin D(GO:0033280)
0.1 0.7 GO:2000009 negative regulation of protein localization to cell surface(GO:2000009)
0.0 0.7 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.2 0.6 GO:1903232 melanosome assembly(GO:1903232)
0.2 0.6 GO:0097402 neuroblast migration(GO:0097402)
0.1 0.6 GO:0070345 negative regulation of fat cell proliferation(GO:0070345)
0.1 0.6 GO:0010032 meiotic chromosome condensation(GO:0010032)
0.1 0.6 GO:2000467 positive regulation of glycogen (starch) synthase activity(GO:2000467)
0.1 0.6 GO:0000244 spliceosomal tri-snRNP complex assembly(GO:0000244)
0.0 0.6 GO:0045792 negative regulation of cell size(GO:0045792)
0.0 0.6 GO:0036065 fucosylation(GO:0036065)
0.0 0.6 GO:0043567 regulation of insulin-like growth factor receptor signaling pathway(GO:0043567)
0.0 0.6 GO:0006924 activation-induced cell death of T cells(GO:0006924)
0.0 0.6 GO:0034063 stress granule assembly(GO:0034063)
0.0 0.6 GO:0050873 brown fat cell differentiation(GO:0050873)
0.0 0.6 GO:0019884 antigen processing and presentation of exogenous antigen(GO:0019884)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 52 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 2.0 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 1.7 GO:0072562 blood microparticle(GO:0072562)
0.0 1.4 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.1 0.8 GO:1990726 Lsm1-7-Pat1 complex(GO:1990726)
0.1 0.7 GO:0031931 TORC1 complex(GO:0031931)
0.0 0.7 GO:0045120 pronucleus(GO:0045120)
0.1 0.6 GO:0000796 condensin complex(GO:0000796)
0.2 0.5 GO:0014802 terminal cisterna(GO:0014802)
0.0 0.5 GO:0031229 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229)
0.0 0.5 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.0 0.5 GO:0005779 integral component of peroxisomal membrane(GO:0005779)
0.1 0.4 GO:0036488 CHOP-C/EBP complex(GO:0036488)
0.1 0.4 GO:0008537 proteasome activator complex(GO:0008537)
0.1 0.4 GO:0005947 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
0.1 0.4 GO:0005784 Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
0.0 0.4 GO:0000124 SAGA complex(GO:0000124)
0.0 0.4 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.0 0.4 GO:0055038 recycling endosome membrane(GO:0055038)
0.0 0.4 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.1 0.3 GO:0097543 ciliary inversin compartment(GO:0097543)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 99 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 4.6 GO:0003735 structural constituent of ribosome(GO:0003735)
0.1 1.4 GO:0070181 small ribosomal subunit rRNA binding(GO:0070181)
0.1 1.2 GO:0001848 complement binding(GO:0001848)
0.1 0.7 GO:0019841 retinol binding(GO:0019841)
0.1 0.6 GO:0061133 endopeptidase activator activity(GO:0061133)
0.1 0.6 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.0 0.6 GO:0001222 transcription corepressor binding(GO:0001222)
0.0 0.6 GO:0000033 alpha-1,3-mannosyltransferase activity(GO:0000033)
0.2 0.5 GO:0031752 D5 dopamine receptor binding(GO:0031752)
0.1 0.5 GO:0004528 phosphodiesterase I activity(GO:0004528)
0.1 0.5 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.1 0.5 GO:0004351 glutamate decarboxylase activity(GO:0004351)
0.1 0.5 GO:0038036 sphingosine-1-phosphate receptor activity(GO:0038036)
0.1 0.5 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 0.5 GO:1990715 mRNA CDS binding(GO:1990715)
0.0 0.5 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.0 0.5 GO:0016594 glycine binding(GO:0016594)
0.0 0.5 GO:0017160 Ral GTPase binding(GO:0017160)
0.0 0.5 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.0 0.5 GO:0005246 calcium channel regulator activity(GO:0005246)