Motif ID: Spdef

Z-value: 0.749


Transcription factors associated with Spdef:

Gene SymbolEntrez IDGene Name
Spdef ENSMUSG00000024215.7 Spdef

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Spdefmm10_v2_chr17_-_27728889_27728956-0.705.4e-03Click!


Activity profile for motif Spdef.

activity profile for motif Spdef


Sorted Z-values histogram for motif Spdef

Sorted Z-values for motif Spdef



Network of associatons between targets according to the STRING database.



First level regulatory network of Spdef

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr15_-_93519499 2.207 ENSMUST00000109255.2
 Prickle1
prickle homolog 1 (Drosophila)
chr9_+_27299205 1.692 ENSMUST00000115247.1
ENSMUST00000133213.1
 Igsf9b

immunoglobulin superfamily, member 9B

chr6_-_99096196 1.294 ENSMUST00000175886.1
 Foxp1
forkhead box P1
chr13_+_12395362 1.204 ENSMUST00000059270.8
 Heatr1
HEAT repeat containing 1
chr8_+_113635550 1.028 ENSMUST00000179926.1
 Mon1b
MON1 homolog b (yeast)
chr9_+_32224457 1.018 ENSMUST00000183121.1
 Arhgap32
Rho GTPase activating protein 32
chr9_+_65908967 1.017 ENSMUST00000034949.3
ENSMUST00000154589.1
 Csnk1g1

casein kinase 1, gamma 1

chr8_+_113635787 0.988 ENSMUST00000035777.8
 Mon1b
MON1 homolog b (yeast)
chr13_+_109632760 0.951 ENSMUST00000135275.1
 Pde4d
phosphodiesterase 4D, cAMP specific
chr8_+_22974844 0.926 ENSMUST00000110688.2
ENSMUST00000121802.2
 Ank1

ankyrin 1, erythroid

chr8_+_109778554 0.924 ENSMUST00000093157.6
 Ap1g1
adaptor protein complex AP-1, gamma 1 subunit
chr8_+_109778863 0.922 ENSMUST00000034171.8
 Ap1g1
adaptor protein complex AP-1, gamma 1 subunit
chr9_+_30427329 0.919 ENSMUST00000164099.1
 Snx19
sorting nexin 19
chr2_+_164805082 0.871 ENSMUST00000052107.4
 Zswim3
zinc finger SWIM-type containing 3
chr11_+_83299005 0.869 ENSMUST00000176944.1
 Ap2b1
adaptor-related protein complex 2, beta 1 subunit
chr10_-_6980376 0.850 ENSMUST00000105617.1
 Ipcef1
interaction protein for cytohesin exchange factors 1
chr5_+_110544326 0.837 ENSMUST00000040001.7
 Galnt9
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 9
chr10_-_63927434 0.834 ENSMUST00000079279.3
 Gm10118
predicted gene 10118
chr15_-_37458523 0.831 ENSMUST00000116445.2
 Ncald
neurocalcin delta
chr9_-_41157459 0.822 ENSMUST00000136530.1
 Ubash3b
ubiquitin associated and SH3 domain containing, B

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 116 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.7 2.2 GO:0051892 negative regulation of cardioblast differentiation(GO:0051892)
0.0 2.1 GO:0035904 aorta development(GO:0035904)
0.7 2.0 GO:0019085 early viral transcription(GO:0019085)
0.6 1.8 GO:0043323 positive regulation of natural killer cell degranulation(GO:0043323)
0.2 1.7 GO:0097151 positive regulation of inhibitory postsynaptic potential(GO:0097151)
0.2 1.3 GO:0032625 interleukin-21 production(GO:0032625) interleukin-21 secretion(GO:0072619)
0.1 1.3 GO:0010763 positive regulation of fibroblast migration(GO:0010763)
0.1 1.2 GO:0045943 positive regulation of transcription from RNA polymerase I promoter(GO:0045943)
0.0 1.1 GO:0032011 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.0 1.1 GO:0030148 sphingolipid biosynthetic process(GO:0030148)
0.1 1.0 GO:1901898 negative regulation of relaxation of muscle(GO:1901078) regulation of cell communication by electrical coupling involved in cardiac conduction(GO:1901844) negative regulation of relaxation of cardiac muscle(GO:1901898)
0.0 1.0 GO:0045761 regulation of adenylate cyclase activity(GO:0045761)
0.0 0.9 GO:0033014 porphyrin-containing compound biosynthetic process(GO:0006779) tetrapyrrole biosynthetic process(GO:0033014)
0.1 0.8 GO:0045779 negative regulation of bone resorption(GO:0045779)
0.1 0.8 GO:0018342 protein prenylation(GO:0018342) prenylation(GO:0097354)
0.0 0.8 GO:0010800 positive regulation of peptidyl-threonine phosphorylation(GO:0010800)
0.1 0.7 GO:0060501 positive regulation of epithelial cell proliferation involved in lung morphogenesis(GO:0060501)
0.0 0.7 GO:0060218 hematopoietic stem cell differentiation(GO:0060218)
0.2 0.6 GO:0086046 membrane depolarization during SA node cell action potential(GO:0086046)
0.2 0.6 GO:0016344 meiotic chromosome movement towards spindle pole(GO:0016344)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 54 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 3.9 GO:0030131 clathrin adaptor complex(GO:0030131)
0.1 1.7 GO:0060077 inhibitory synapse(GO:0060077)
0.0 1.5 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 1.3 GO:0032420 stereocilium(GO:0032420)
0.4 1.2 GO:0034455 t-UTP complex(GO:0034455)
0.0 0.9 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.2 0.8 GO:0032280 symmetric synapse(GO:0032280)
0.1 0.8 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 0.8 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.1 0.7 GO:0008623 CHRAC(GO:0008623)
0.0 0.7 GO:0031901 early endosome membrane(GO:0031901)
0.2 0.6 GO:1990415 Pex17p-Pex14p docking complex(GO:1990415) peroxisomal importomer complex(GO:1990429)
0.1 0.6 GO:0030478 actin cap(GO:0030478)
0.0 0.6 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.0 0.5 GO:0098984 asymmetric synapse(GO:0032279) neuron to neuron synapse(GO:0098984)
0.1 0.4 GO:0097441 basilar dendrite(GO:0097441)
0.1 0.4 GO:0097427 microtubule bundle(GO:0097427)
0.0 0.4 GO:0030008 TRAPP complex(GO:0030008)
0.0 0.4 GO:0071598 neuronal ribonucleoprotein granule(GO:0071598)
0.0 0.4 GO:0008385 IkappaB kinase complex(GO:0008385)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 73 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 2.8 GO:0030276 clathrin binding(GO:0030276)
0.1 1.9 GO:0030742 GTP-dependent protein binding(GO:0030742)
0.1 1.5 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.0 1.5 GO:0008186 ATP-dependent RNA helicase activity(GO:0004004) RNA-dependent ATPase activity(GO:0008186)
0.0 1.5 GO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
0.0 1.3 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.0 1.2 GO:0030515 snoRNA binding(GO:0030515)
0.4 1.1 GO:0047256 beta-galactosyl-N-acetylglucosaminylgalactosylglucosyl-ceramide beta-1,3-acetylglucosaminyltransferase activity(GO:0008457) lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase activity(GO:0047256)
0.1 1.0 GO:0008179 adenylate cyclase binding(GO:0008179)
0.0 1.0 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.0 1.0 GO:0004120 calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117) cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118) cGMP-inhibited cyclic-nucleotide phosphodiesterase activity(GO:0004119) photoreceptor cyclic-nucleotide phosphodiesterase activity(GO:0004120) 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate phosphodiesterase activity(GO:0044688) inositol phosphosphingolipid phospholipase activity(GO:0052712) inositol phosphorylceramide phospholipase activity(GO:0052713) mannosyl-inositol phosphorylceramide phospholipase activity(GO:0052714) mannosyl-diinositol phosphorylceramide phospholipase activity(GO:0052715)
0.0 1.0 GO:0000009 alpha-1,6-mannosyltransferase activity(GO:0000009)
0.0 0.9 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.0 0.9 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.1 0.8 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.1 0.8 GO:0008318 protein prenyltransferase activity(GO:0008318)
0.0 0.8 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.0 0.8 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.2 0.7 GO:0022865 transmembrane electron transfer carrier(GO:0022865)
0.1 0.7 GO:0004445 inositol-polyphosphate 5-phosphatase activity(GO:0004445)