Motif ID: Srf

Z-value: 1.399


Transcription factors associated with Srf:

Gene SymbolEntrez IDGene Name
Srf ENSMUSG00000015605.5 Srf

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Srfmm10_v2_chr17_-_46556158_465561880.195.2e-01Click!


Activity profile for motif Srf.

activity profile for motif Srf


Sorted Z-values histogram for motif Srf

Sorted Z-values for motif Srf



Network of associatons between targets according to the STRING database.



First level regulatory network of Srf

PNG image of the network

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Top targets:


Showing 1 to 20 of 88 entries
PromoterScoreRefseqGene SymbolGene Name
chr18_+_34861200 14.789 ENSMUST00000165033.1
 Egr1
early growth response 1
chr7_-_142661305 5.915 ENSMUST00000105936.1
 Igf2
insulin-like growth factor 2
chr2_+_156775409 2.971 ENSMUST00000088552.6
 Myl9
myosin, light polypeptide 9, regulatory
chr7_-_19310035 2.569 ENSMUST00000003640.2
 Fosb
FBJ osteosarcoma oncogene B
chr12_+_85473883 2.493 ENSMUST00000021674.6
 Fos
FBJ osteosarcoma oncogene
chr10_+_79988584 2.478 ENSMUST00000004784.4
ENSMUST00000105374.1
 Cnn2

calponin 2

chr7_-_142661858 2.257 ENSMUST00000145896.2
 Igf2
insulin-like growth factor 2
chr7_-_44997221 1.736 ENSMUST00000152341.1
 Bcl2l12
BCL2-like 12 (proline rich)
chrX_+_101449078 1.488 ENSMUST00000033674.5
 Itgb1bp2
integrin beta 1 binding protein 2
chr10_-_120899067 1.205 ENSMUST00000092143.5
 Msrb3
methionine sulfoxide reductase B3
chr2_+_127336152 1.171 ENSMUST00000028846.6
 Dusp2
dual specificity phosphatase 2
chr10_+_67537861 1.139 ENSMUST00000048289.7
ENSMUST00000105438.2
ENSMUST00000130933.1
ENSMUST00000146986.1
 Egr2



early growth response 2



chr3_-_57575907 1.113 ENSMUST00000120977.1
 Wwtr1
WW domain containing transcription regulator 1
chr1_+_74391479 0.956 ENSMUST00000027367.7
 Ctdsp1
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1
chr7_+_101896817 0.920 ENSMUST00000143835.1
 Anapc15
anaphase prompoting complex C subunit 15
chr2_+_154548888 0.838 ENSMUST00000045116.4
ENSMUST00000109709.3
 1700003F12Rik

RIKEN cDNA 1700003F12 gene

chr1_-_43163891 0.833 ENSMUST00000008280.7
 Fhl2
four and a half LIM domains 2
chr7_-_44997535 0.799 ENSMUST00000124232.1
ENSMUST00000003290.4
 Bcl2l12

BCL2-like 12 (proline rich)

chr4_+_101986626 0.797 ENSMUST00000106914.1
 Gm12789
predicted gene 12789
chr6_-_132314757 0.784 ENSMUST00000048686.8
 Prpmp5
proline-rich protein MP5

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 30 entries
Log-likelihood per target Total log-likelihoodTermDescription
4.9 14.8 GO:0072223 metanephric glomerular mesangium development(GO:0072223) metanephric glomerular mesangial cell proliferation involved in metanephros development(GO:0072262)
1.0 8.2 GO:0038028 insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028)
0.0 2.9 GO:0070527 platelet aggregation(GO:0070527)
0.1 2.6 GO:0071277 cellular response to calcium ion(GO:0071277)
0.3 2.5 GO:1902166 negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:1902166)
0.1 2.5 GO:0050765 negative regulation of phagocytosis(GO:0050765)
0.1 2.5 GO:0035994 response to muscle stretch(GO:0035994)
0.1 1.6 GO:1903504 regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090266) regulation of mitotic spindle checkpoint(GO:1903504)
0.0 1.6 GO:0001706 endoderm formation(GO:0001706)
0.2 1.2 GO:0030091 protein repair(GO:0030091)
0.2 1.1 GO:0021593 rhombomere morphogenesis(GO:0021593)
0.2 1.1 GO:0072257 metanephric nephron tubule epithelial cell differentiation(GO:0072257) regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072307)
0.1 1.1 GO:0090136 epithelial cell-cell adhesion(GO:0090136)
0.0 1.1 GO:2000179 positive regulation of neural precursor cell proliferation(GO:2000179)
0.1 1.0 GO:0030579 ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.0 1.0 GO:2000134 negative regulation of G1/S transition of mitotic cell cycle(GO:2000134)
0.3 0.8 GO:0006116 NADH oxidation(GO:0006116)
0.1 0.8 GO:1904715 negative regulation of chaperone-mediated autophagy(GO:1904715)
0.1 0.8 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.1 0.8 GO:0006488 dolichol-linked oligosaccharide biosynthetic process(GO:0006488)

Gene overrepresentation in cellular_component category:

Showing 1 to 13 of 13 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 3.1 GO:0016460 myosin II complex(GO:0016460)
0.1 1.6 GO:0005680 anaphase-promoting complex(GO:0005680)
0.0 1.3 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0 1.2 GO:0030018 Z disc(GO:0030018)
0.0 0.9 GO:0090544 BAF-type complex(GO:0090544)
0.1 0.8 GO:0005916 fascia adherens(GO:0005916)
0.0 0.8 GO:0031430 M band(GO:0031430)
0.0 0.5 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0 0.4 GO:0030285 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.0 0.4 GO:0031229 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229)
0.0 0.2 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.0 0.1 GO:0005927 muscle tendon junction(GO:0005927)
0.0 0.1 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 23 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.8 14.8 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.4 8.2 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.3 3.0 GO:0032036 myosin heavy chain binding(GO:0032036)
0.1 2.5 GO:0070412 R-SMAD binding(GO:0070412)
0.0 2.5 GO:0002039 p53 binding(GO:0002039)
0.0 2.2 GO:0005516 calmodulin binding(GO:0005516)
0.0 1.6 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0 1.4 GO:0005178 integrin binding(GO:0005178)
0.2 1.2 GO:0070191 methionine-R-sulfoxide reductase activity(GO:0070191)
0.0 1.1 GO:0071837 HMG box domain binding(GO:0071837)
0.1 1.0 GO:0048495 Roundabout binding(GO:0048495)
0.1 1.0 GO:0008420 CTD phosphatase activity(GO:0008420)
0.2 0.8 GO:0004090 carbonyl reductase (NADPH) activity(GO:0004090)
0.1 0.8 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.1 0.8 GO:0045294 alpha-catenin binding(GO:0045294)
0.1 0.7 GO:0004886 9-cis retinoic acid receptor activity(GO:0004886)
0.2 0.6 GO:0043912 D-lysine oxidase activity(GO:0043912)
0.0 0.3 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.0 0.2 GO:0043495 protein anchor(GO:0043495)
0.0 0.1 GO:0070878 primary miRNA binding(GO:0070878)