Motif ID: Stat1

Z-value: 0.473


Transcription factors associated with Stat1:

Gene SymbolEntrez IDGene Name
Stat1 ENSMUSG00000026104.8 Stat1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Stat1mm10_v2_chr1_+_52119438_521194990.621.8e-02Click!


Activity profile for motif Stat1.

activity profile for motif Stat1


Sorted Z-values histogram for motif Stat1

Sorted Z-values for motif Stat1



Network of associatons between targets according to the STRING database.



First level regulatory network of Stat1

PNG image of the network

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Top targets:


Showing 1 to 20 of 138 entries
PromoterScoreRefseqGene SymbolGene Name
chr11_+_78499087 1.202 ENSMUST00000017488.4
Vtn
vitronectin
chr15_-_93519499 0.850 ENSMUST00000109255.2
Prickle1
prickle homolog 1 (Drosophila)
chr18_-_52529847 0.674 ENSMUST00000171470.1
Lox
lysyl oxidase
chr1_+_90203980 0.487 ENSMUST00000065587.4
ENSMUST00000159654.1
Ackr3

atypical chemokine receptor 3

chr18_-_52529692 0.480 ENSMUST00000025409.7
Lox
lysyl oxidase
chr2_-_84775388 0.447 ENSMUST00000023994.3
Serping1
serine (or cysteine) peptidase inhibitor, clade G, member 1
chr11_+_3488275 0.396 ENSMUST00000064265.6
Pla2g3
phospholipase A2, group III
chr9_+_86743616 0.395 ENSMUST00000036426.6
Prss35
protease, serine, 35
chr7_-_126625676 0.385 ENSMUST00000032961.3
Nupr1
nuclear protein transcription regulator 1
chr17_+_34187545 0.380 ENSMUST00000170086.1
Tap1
transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
chr17_+_34187789 0.376 ENSMUST00000041633.8
Tap1
transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
chr8_-_105326252 0.368 ENSMUST00000070508.7
Lrrc29
leucine rich repeat containing 29
chr3_-_108210438 0.351 ENSMUST00000117784.1
ENSMUST00000119650.1
ENSMUST00000117409.1
Atxn7l2


ataxin 7-like 2


chrX_-_73930751 0.346 ENSMUST00000155597.1
ENSMUST00000114379.1
Renbp

renin binding protein

chr15_+_34238026 0.344 ENSMUST00000022867.3
Laptm4b
lysosomal-associated protein transmembrane 4B
chr2_-_84775420 0.327 ENSMUST00000111641.1
Serping1
serine (or cysteine) peptidase inhibitor, clade G, member 1
chr10_+_18235030 0.321 ENSMUST00000181897.1
Gm10827
predicted gene 10827
chr3_+_97032416 0.314 ENSMUST00000132256.1
ENSMUST00000072600.6
Gja5

gap junction protein, alpha 5

chr9_+_86743641 0.310 ENSMUST00000179574.1
Prss35
protease, serine, 35
chr3_-_80802789 0.302 ENSMUST00000107745.1
ENSMUST00000075316.4
Gria2

glutamate receptor, ionotropic, AMPA2 (alpha 2)


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 31 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 1.2 GO:0048251 elastic fiber assembly(GO:0048251)
0.1 1.2 GO:0097421 liver regeneration(GO:0097421)
0.3 0.8 GO:0051892 negative regulation of cardioblast differentiation(GO:0051892)
0.3 0.8 GO:0001869 regulation of complement activation, lectin pathway(GO:0001868) negative regulation of complement activation, lectin pathway(GO:0001869)
0.2 0.8 GO:0051708 intracellular transport of viral protein in host cell(GO:0019060) symbiont intracellular protein transport in host(GO:0030581) cytosol to ER transport(GO:0046967) intracellular protein transport in other organism involved in symbiotic interaction(GO:0051708)
0.0 0.6 GO:0019262 N-acetylneuraminate catabolic process(GO:0019262)
0.2 0.5 GO:1901097 negative regulation of autophagosome maturation(GO:1901097)
0.1 0.5 GO:0001999 renal response to blood flow involved in circulatory renin-angiotensin regulation of systemic arterial blood pressure(GO:0001999)
0.0 0.5 GO:0071378 growth hormone receptor signaling pathway(GO:0060396) cellular response to growth hormone stimulus(GO:0071378)
0.0 0.5 GO:0009409 response to cold(GO:0009409)
0.0 0.5 GO:1902230 negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902230)
0.1 0.4 GO:0019372 lipoxygenase pathway(GO:0019372)
0.1 0.4 GO:0034638 phosphatidylcholine catabolic process(GO:0034638)
0.0 0.4 GO:2000194 regulation of female gonad development(GO:2000194)
0.1 0.3 GO:2000253 positive regulation of feeding behavior(GO:2000253)
0.1 0.3 GO:0030643 cellular phosphate ion homeostasis(GO:0030643) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.0 0.3 GO:0042730 fibrinolysis(GO:0042730)
0.0 0.3 GO:0035235 ionotropic glutamate receptor signaling pathway(GO:0035235)
0.0 0.2 GO:0030259 lipid glycosylation(GO:0030259)
0.0 0.2 GO:0060576 intestinal epithelial cell development(GO:0060576)

Gene overrepresentation in cellular_component category:

Showing 1 to 9 of 9 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 1.5 GO:0005796 Golgi lumen(GO:0005796)
0.0 1.0 GO:0005581 collagen trimer(GO:0005581)
0.1 0.8 GO:0042825 TAP complex(GO:0042825)
0.0 0.3 GO:0005922 connexon complex(GO:0005922)
0.0 0.3 GO:0032279 asymmetric synapse(GO:0032279)
0.1 0.2 GO:0035061 interchromatin granule(GO:0035061)
0.0 0.1 GO:0070557 PCNA-p21 complex(GO:0070557)
0.0 0.1 GO:0060187 cell pole(GO:0060187)
0.0 0.1 GO:1990111 spermatoproteasome complex(GO:1990111)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 20 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.4 1.2 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.1 1.2 GO:0001871 pattern binding(GO:0001871) scavenger receptor activity(GO:0005044) polysaccharide binding(GO:0030247)
0.2 0.8 GO:0023029 peptide antigen-transporting ATPase activity(GO:0015433) MHC class Ib protein binding(GO:0023029) tapasin binding(GO:0046980)
0.0 0.7 GO:0001848 complement binding(GO:0001848)
0.0 0.6 GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
0.2 0.5 GO:0016494 C-X-C chemokine receptor activity(GO:0016494) C-X-C chemokine binding(GO:0019958)
0.1 0.5 GO:0008269 JAK pathway signal transduction adaptor activity(GO:0008269)
0.0 0.5 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.1 0.4 GO:0004528 phosphodiesterase I activity(GO:0004528)
0.1 0.3 GO:0071253 connexin binding(GO:0071253)
0.1 0.3 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.0 0.3 GO:0001618 virus receptor activity(GO:0001618)
0.0 0.3 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 0.3 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.0 0.2 GO:0047276 N-acetyllactosaminide 3-alpha-galactosyltransferase activity(GO:0047276)
0.0 0.2 GO:0001162 RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding(GO:0001162)
0.0 0.2 GO:0048018 receptor agonist activity(GO:0048018)
0.0 0.1 GO:0000402 open form four-way junction DNA binding(GO:0000401) crossed form four-way junction DNA binding(GO:0000402)
0.0 0.1 GO:0019962 interferon receptor activity(GO:0004904) type I interferon receptor activity(GO:0004905) type I interferon binding(GO:0019962) interleukin-20 binding(GO:0042015)
0.0 0.1 GO:0048408 epidermal growth factor binding(GO:0048408)