Motif ID: Stat2
Z-value: 2.394
Transcription factors associated with Stat2:
| Gene Symbol | Entrez ID | Gene Name |
|---|---|---|
| Stat2 | ENSMUSG00000040033.9 | Stat2 |
Activity-expression correlation:
| Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| Stat2 | mm10_v2_chr10_+_128270546_128270577 | -0.60 | 2.4e-02 | Click! |
Top targets:
Showing 1 to 20 of 200 entries
Gene overrepresentation in biological_process category:
Showing 1 to 20 of 96 entries
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.8 | 32.9 | GO:0045071 | negative regulation of viral genome replication(GO:0045071) |
| 0.4 | 11.6 | GO:0032728 | positive regulation of interferon-beta production(GO:0032728) |
| 0.4 | 10.9 | GO:0035456 | response to interferon-beta(GO:0035456) |
| 2.1 | 6.4 | GO:2000562 | negative regulation of interferon-gamma secretion(GO:1902714) negative regulation of CD4-positive, alpha-beta T cell proliferation(GO:2000562) |
| 0.1 | 6.0 | GO:0046825 | regulation of protein export from nucleus(GO:0046825) |
| 1.4 | 5.6 | GO:1901252 | regulation of intracellular transport of viral material(GO:1901252) |
| 1.6 | 4.9 | GO:0002578 | negative regulation of antigen processing and presentation(GO:0002578) |
| 0.6 | 4.9 | GO:0031666 | positive regulation of lipopolysaccharide-mediated signaling pathway(GO:0031666) |
| 0.0 | 4.5 | GO:0016579 | protein deubiquitination(GO:0016579) |
| 1.5 | 4.4 | GO:1902524 | negative regulation of interferon-alpha production(GO:0032687) interferon-alpha biosynthetic process(GO:0045349) regulation of interferon-alpha biosynthetic process(GO:0045354) negative regulation of interferon-beta biosynthetic process(GO:0045358) positive regulation of protein K48-linked ubiquitination(GO:1902524) |
| 1.0 | 4.0 | GO:1900122 | positive regulation of receptor binding(GO:1900122) |
| 0.6 | 3.9 | GO:0060330 | regulation of response to interferon-gamma(GO:0060330) |
| 0.9 | 3.7 | GO:0044565 | dendritic cell proliferation(GO:0044565) |
| 0.1 | 3.5 | GO:0016082 | synaptic vesicle priming(GO:0016082) |
| 0.5 | 3.4 | GO:0090336 | positive regulation of brown fat cell differentiation(GO:0090336) |
| 0.1 | 3.1 | GO:0042632 | cholesterol homeostasis(GO:0042632) sterol homeostasis(GO:0055092) |
| 1.0 | 2.9 | GO:0042560 | 10-formyltetrahydrofolate catabolic process(GO:0009258) folic acid-containing compound catabolic process(GO:0009397) pteridine-containing compound catabolic process(GO:0042560) |
| 0.4 | 2.9 | GO:0048625 | myoblast fate commitment(GO:0048625) |
| 0.9 | 2.8 | GO:1904139 | microglial cell migration(GO:1904124) regulation of microglial cell migration(GO:1904139) |
| 0.9 | 2.7 | GO:0002741 | positive regulation of cytokine secretion involved in immune response(GO:0002741) |
Gene overrepresentation in cellular_component category:
Showing 1 to 20 of 47 entries
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 23.2 | GO:0045177 | apical part of cell(GO:0045177) |
| 0.1 | 8.3 | GO:0016363 | nuclear matrix(GO:0016363) |
| 0.1 | 6.0 | GO:0005637 | nuclear inner membrane(GO:0005637) |
| 0.1 | 5.2 | GO:0005788 | endoplasmic reticulum lumen(GO:0005788) |
| 0.8 | 4.0 | GO:1990357 | terminal web(GO:1990357) |
| 0.4 | 4.0 | GO:1990712 | HFE-transferrin receptor complex(GO:1990712) |
| 0.1 | 3.5 | GO:0042734 | presynaptic membrane(GO:0042734) |
| 0.1 | 3.1 | GO:0000788 | nuclear nucleosome(GO:0000788) |
| 0.3 | 2.9 | GO:0070369 | beta-catenin-TCF7L2 complex(GO:0070369) |
| 0.0 | 2.4 | GO:0072562 | blood microparticle(GO:0072562) |
| 0.3 | 2.3 | GO:0033269 | internode region of axon(GO:0033269) |
| 0.2 | 2.3 | GO:0098643 | fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643) |
| 0.1 | 2.2 | GO:0016592 | mediator complex(GO:0016592) |
| 0.0 | 2.0 | GO:0031519 | PcG protein complex(GO:0031519) |
| 0.6 | 1.9 | GO:1990682 | CSF1-CSF1R complex(GO:1990682) |
| 0.5 | 1.9 | GO:0043020 | NADPH oxidase complex(GO:0043020) |
| 0.0 | 1.9 | GO:0005770 | late endosome(GO:0005770) |
| 0.2 | 1.8 | GO:0020003 | symbiont-containing vacuole(GO:0020003) |
| 0.2 | 1.6 | GO:0042629 | mast cell granule(GO:0042629) |
| 0.0 | 1.5 | GO:0032587 | ruffle membrane(GO:0032587) |
Gene overrepresentation in molecular_function category:
Showing 1 to 20 of 83 entries
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 16.8 | GO:0001078 | transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078) |
| 0.5 | 9.9 | GO:0003950 | NAD+ ADP-ribosyltransferase activity(GO:0003950) |
| 0.6 | 8.3 | GO:0016443 | bidentate ribonuclease III activity(GO:0016443) |
| 0.6 | 7.3 | GO:0008191 | metalloendopeptidase inhibitor activity(GO:0008191) |
| 1.1 | 6.4 | GO:0016936 | galactoside binding(GO:0016936) |
| 0.3 | 6.0 | GO:0005521 | lamin binding(GO:0005521) |
| 0.0 | 5.6 | GO:0005525 | GTP binding(GO:0005525) |
| 0.5 | 5.5 | GO:0016920 | pyroglutamyl-peptidase activity(GO:0016920) |
| 0.1 | 4.6 | GO:0016836 | hydro-lyase activity(GO:0016836) |
| 0.1 | 4.5 | GO:0033613 | activating transcription factor binding(GO:0033613) |
| 0.2 | 4.3 | GO:0005044 | scavenger receptor activity(GO:0005044) |
| 0.1 | 4.2 | GO:0005547 | phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547) |
| 0.5 | 4.0 | GO:0039706 | co-receptor binding(GO:0039706) |
| 0.2 | 3.2 | GO:0031386 | protein tag(GO:0031386) |
| 0.8 | 3.1 | GO:0047844 | deoxycytidine deaminase activity(GO:0047844) |
| 0.2 | 3.1 | GO:0017128 | phospholipid scramblase activity(GO:0017128) |
| 1.0 | 2.9 | GO:0016155 | formyltetrahydrofolate dehydrogenase activity(GO:0016155) |
| 0.1 | 2.9 | GO:0045295 | gamma-catenin binding(GO:0045295) |
| 0.2 | 2.4 | GO:0004886 | 9-cis retinoic acid receptor activity(GO:0004886) |
| 0.1 | 2.3 | GO:0005201 | extracellular matrix structural constituent(GO:0005201) |
