Motif ID: Stat5a

Z-value: 1.108


Transcription factors associated with Stat5a:

Gene SymbolEntrez IDGene Name
Stat5a ENSMUSG00000004043.8 Stat5a



Activity profile for motif Stat5a.

activity profile for motif Stat5a


Sorted Z-values histogram for motif Stat5a

Sorted Z-values for motif Stat5a



Network of associatons between targets according to the STRING database.



First level regulatory network of Stat5a

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr17_+_22689771 3.888 ENSMUST00000055305.8
 Gm9805
predicted gene 9805
chr4_-_136898803 2.552 ENSMUST00000046285.5
 C1qa
complement component 1, q subcomponent, alpha polypeptide
chr10_-_117282262 1.675 ENSMUST00000092163.7
 Lyz2
lysozyme 2
chr4_-_64046925 1.642 ENSMUST00000107377.3
 Tnc
tenascin C
chr2_+_14229390 1.555 ENSMUST00000028045.2
 Mrc1
mannose receptor, C type 1
chr8_-_71537402 1.391 ENSMUST00000051672.7
 Bst2
bone marrow stromal cell antigen 2
chr18_+_20665250 1.386 ENSMUST00000075312.3
 Ttr
transthyretin
chr5_+_104435112 1.308 ENSMUST00000031243.8
ENSMUST00000086833.6
ENSMUST00000112748.1
ENSMUST00000112746.1
ENSMUST00000145084.1
ENSMUST00000132457.1
 Spp1





secreted phosphoprotein 1





chr10_-_76725978 1.262 ENSMUST00000001147.4
 Col6a1
collagen, type VI, alpha 1
chr11_-_100970887 1.227 ENSMUST00000060792.5
 Ptrf
polymerase I and transcript release factor
chr11_+_78499087 1.215 ENSMUST00000017488.4
 Vtn
vitronectin
chr11_+_94936224 1.124 ENSMUST00000001547.7
 Col1a1
collagen, type I, alpha 1
chr11_-_55419898 1.078 ENSMUST00000108858.1
ENSMUST00000141530.1
 Sparc

secreted acidic cysteine rich glycoprotein

chr9_-_77347787 1.032 ENSMUST00000184848.1
ENSMUST00000184415.1
 Mlip

muscular LMNA-interacting protein

chr5_-_77408034 0.993 ENSMUST00000163898.1
ENSMUST00000046746.6
 Igfbp7

insulin-like growth factor binding protein 7

chr7_+_88278085 0.943 ENSMUST00000032779.5
ENSMUST00000128791.1
 Ctsc

cathepsin C

chr7_+_107567445 0.926 ENSMUST00000120990.1
 Olfml1
olfactomedin-like 1
chr18_-_36726730 0.913 ENSMUST00000061829.6
 Cd14
CD14 antigen
chr11_+_82101836 0.895 ENSMUST00000000194.3
 Ccl12
chemokine (C-C motif) ligand 12
chr7_-_126625676 0.893 ENSMUST00000032961.3
 Nupr1
nuclear protein transcription regulator 1

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 290 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 2.4 GO:0050829 defense response to Gram-negative bacterium(GO:0050829)
0.1 2.3 GO:0006958 complement activation, classical pathway(GO:0006958)
0.1 2.3 GO:0001913 T cell mediated cytotoxicity(GO:0001913)
0.1 2.2 GO:0010614 negative regulation of cardiac muscle hypertrophy(GO:0010614)
0.4 1.8 GO:2000298 regulation of Rho-dependent protein serine/threonine kinase activity(GO:2000298)
0.4 1.6 GO:0014012 peripheral nervous system axon regeneration(GO:0014012)
0.1 1.6 GO:0071353 cellular response to interleukin-4(GO:0071353)
0.3 1.4 GO:1901252 regulation of intracellular transport of viral material(GO:1901252)
0.3 1.4 GO:0070327 thyroid hormone transport(GO:0070327)
0.2 1.3 GO:0034638 phosphatidylcholine catabolic process(GO:0034638)
0.1 1.3 GO:0097421 liver regeneration(GO:0097421)
0.1 1.3 GO:0070208 protein heterotrimerization(GO:0070208)
0.2 1.2 GO:0006363 termination of RNA polymerase I transcription(GO:0006363)
0.1 1.2 GO:0033280 response to vitamin D(GO:0033280)
0.2 1.1 GO:0036072 intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.2 1.0 GO:0071726 response to diacyl bacterial lipopeptide(GO:0071724) cellular response to diacyl bacterial lipopeptide(GO:0071726)
0.1 1.0 GO:0046688 response to copper ion(GO:0046688)
0.0 1.0 GO:0001937 negative regulation of endothelial cell proliferation(GO:0001937)
0.3 0.9 GO:2000402 negative regulation of lymphocyte migration(GO:2000402)
0.1 0.9 GO:0042730 fibrinolysis(GO:0042730)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 120 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 3.8 GO:0005581 collagen trimer(GO:0005581)
0.7 3.3 GO:0048237 rough endoplasmic reticulum lumen(GO:0048237)
0.0 2.3 GO:0031225 anchored component of membrane(GO:0031225)
0.1 2.2 GO:0005614 interstitial matrix(GO:0005614)
0.0 2.2 GO:0005901 caveola(GO:0005901)
0.4 1.8 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.0 1.6 GO:0016605 PML body(GO:0016605)
0.0 1.2 GO:0044298 cell body membrane(GO:0044298)
0.4 1.1 GO:0005584 collagen type I trimer(GO:0005584)
0.3 1.1 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.0 1.1 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 1.0 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.1 0.9 GO:0005688 U6 snRNP(GO:0005688)
0.1 0.9 GO:0042612 MHC class I protein complex(GO:0042612)
0.3 0.8 GO:0032311 angiogenin-PRI complex(GO:0032311)
0.3 0.8 GO:0034684 integrin alphav-beta5 complex(GO:0034684)
0.1 0.8 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.1 0.7 GO:1990357 terminal web(GO:1990357)
0.0 0.7 GO:0005605 basal lamina(GO:0005605)
0.1 0.6 GO:0032009 early phagosome(GO:0032009)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 190 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 4.0 GO:0050840 extracellular matrix binding(GO:0050840)
0.2 2.4 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.0 2.3 GO:0001191 transcriptional repressor activity, RNA polymerase II transcription factor binding(GO:0001191)
0.2 1.9 GO:0070324 thyroid hormone binding(GO:0070324)
0.3 1.8 GO:0045545 syndecan binding(GO:0045545)
0.2 1.8 GO:0035615 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.0 1.8 GO:0005507 copper ion binding(GO:0005507)
0.4 1.7 GO:0031727 CCR2 chemokine receptor binding(GO:0031727)
0.1 1.6 GO:0005537 mannose binding(GO:0005537)
0.1 1.5 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 1.4 GO:0005178 integrin binding(GO:0005178)
0.3 1.3 GO:0004528 phosphodiesterase I activity(GO:0004528)
0.0 1.3 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.2 1.2 GO:0042134 rRNA primary transcript binding(GO:0042134)
0.1 1.2 GO:0008242 omega peptidase activity(GO:0008242)
0.1 1.0 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.0 1.0 GO:0004601 peroxidase activity(GO:0004601)
0.2 0.9 GO:0070891 lipoteichoic acid binding(GO:0070891)
0.2 0.9 GO:0016724 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.1 0.9 GO:0016505 peptidase activator activity involved in apoptotic process(GO:0016505)