Motif ID: Stat6

Z-value: 0.728


Transcription factors associated with Stat6:

Gene SymbolEntrez IDGene Name
Stat6 ENSMUSG00000002147.12 Stat6

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Stat6mm10_v2_chr10_+_127642975_1276430340.146.3e-01Click!


Activity profile for motif Stat6.

activity profile for motif Stat6


Sorted Z-values histogram for motif Stat6

Sorted Z-values for motif Stat6



Network of associatons between targets according to the STRING database.



First level regulatory network of Stat6

PNG image of the network

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Top targets:


Showing 1 to 20 of 152 entries
PromoterScoreRefseqGene SymbolGene Name
chr19_+_12846773 1.009 ENSMUST00000164001.1
 Gm5244
predicted pseudogene 5244
chr7_+_66839752 0.844 ENSMUST00000107478.1
 Adamts17
a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 17
chrX_-_61185558 0.839 ENSMUST00000166381.1
 Cdr1
cerebellar degeneration related antigen 1
chr7_+_66839726 0.810 ENSMUST00000098382.3
 Adamts17
a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 17
chr11_-_102579461 0.771 ENSMUST00000107081.1
 Gm11627
predicted gene 11627
chr19_-_50030735 0.735 ENSMUST00000071866.1
 Rpl13a-ps1
ribosomal protein 13A, pseudogene 1
chr15_+_25773985 0.689 ENSMUST00000125667.1
 Myo10
myosin X
chr1_-_125913101 0.679 ENSMUST00000161361.1
 Lypd1
Ly6/Plaur domain containing 1
chr2_-_14056029 0.654 ENSMUST00000074854.7
 Ptpla
protein tyrosine phosphatase-like (proline instead of catalytic arginine), member a
chr7_-_127286385 0.645 ENSMUST00000172206.2
 Gm17511
predicted gene, 17511
chr7_+_126766397 0.642 ENSMUST00000032944.7
 Gdpd3
glycerophosphodiester phosphodiesterase domain containing 3
chr18_+_50053282 0.637 ENSMUST00000148159.2
 Tnfaip8
tumor necrosis factor, alpha-induced protein 8
chr8_-_106573461 0.608 ENSMUST00000073722.5
 Gm10073
predicted pseudogene 10073
chr3_+_97032416 0.595 ENSMUST00000132256.1
ENSMUST00000072600.6
 Gja5

gap junction protein, alpha 5

chr14_-_21989475 0.564 ENSMUST00000043409.7
 Zfp503
zinc finger protein 503
chr11_+_75531690 0.534 ENSMUST00000149727.1
ENSMUST00000042561.7
ENSMUST00000108433.1
ENSMUST00000143035.1
 Slc43a2



solute carrier family 43, member 2



chr10_-_19015347 0.533 ENSMUST00000019997.4
 Tnfaip3
tumor necrosis factor, alpha-induced protein 3
chr6_-_4086914 0.522 ENSMUST00000049166.4
 Bet1
blocked early in transport 1 homolog (S. cerevisiae)
chr15_-_33405976 0.509 ENSMUST00000079057.6
 1700084J12Rik
RIKEN cDNA 1700084J12 gene
chr5_+_139543889 0.496 ENSMUST00000174792.1
ENSMUST00000031523.8
 Uncx

UNC homeobox


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 42 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 1.0 GO:0095500 acetylcholine receptor signaling pathway(GO:0095500) postsynaptic signal transduction(GO:0098926) signal transduction involved in cellular response to ammonium ion(GO:1903831) response to acetylcholine(GO:1905144) cellular response to acetylcholine(GO:1905145)
0.1 0.8 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.0 0.8 GO:0015807 L-amino acid transport(GO:0015807)
0.2 0.7 GO:0051708 intracellular transport of viral protein in host cell(GO:0019060) symbiont intracellular protein transport in host(GO:0030581) cytosol to ER transport(GO:0046967) intracellular protein transport in other organism involved in symbiotic interaction(GO:0051708)
0.2 0.6 GO:0086017 renin secretion into blood stream(GO:0002001) cell communication by chemical coupling(GO:0010643) Purkinje myocyte action potential(GO:0086017) regulation of renin secretion into blood stream(GO:1900133)
0.2 0.6 GO:0070315 G1 to G0 transition involved in cell differentiation(GO:0070315)
0.2 0.5 GO:0070428 granuloma formation(GO:0002432) negative regulation of toll-like receptor 3 signaling pathway(GO:0034140) toll-like receptor 5 signaling pathway(GO:0034146) regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070428)
0.2 0.5 GO:1902524 negative regulation of interferon-alpha production(GO:0032687) interferon-alpha biosynthetic process(GO:0045349) regulation of interferon-alpha biosynthetic process(GO:0045354) negative regulation of interferon-beta biosynthetic process(GO:0045358) positive regulation of protein K48-linked ubiquitination(GO:1902524)
0.1 0.5 GO:0035726 common myeloid progenitor cell proliferation(GO:0035726)
0.0 0.5 GO:0048280 vesicle fusion with Golgi apparatus(GO:0048280)
0.0 0.5 GO:0031507 heterochromatin assembly(GO:0031507)
0.0 0.5 GO:0043011 myeloid dendritic cell differentiation(GO:0043011)
0.1 0.4 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
0.0 0.4 GO:0031274 positive regulation of pseudopodium assembly(GO:0031274)
0.0 0.4 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.0 0.4 GO:0018345 protein palmitoylation(GO:0018345)
0.1 0.3 GO:0045659 regulation of neutrophil differentiation(GO:0045658) negative regulation of neutrophil differentiation(GO:0045659)
0.1 0.3 GO:1900740 regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900739) positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900740)
0.1 0.3 GO:0070966 nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966)
0.0 0.3 GO:0016081 synaptic vesicle docking(GO:0016081)

Gene overrepresentation in cellular_component category:

Showing 1 to 18 of 18 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 0.8 GO:0035686 sperm fibrous sheath(GO:0035686)
0.1 0.7 GO:0042825 TAP complex(GO:0042825)
0.0 0.7 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 0.6 GO:0005922 connexon complex(GO:0005922)
0.0 0.5 GO:0005677 chromatin silencing complex(GO:0005677)
0.0 0.5 GO:0005801 cis-Golgi network(GO:0005801)
0.0 0.4 GO:0031932 TORC2 complex(GO:0031932)
0.0 0.4 GO:0098644 complex of collagen trimers(GO:0098644)
0.1 0.3 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.0 0.3 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.0 0.3 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.0 0.2 GO:0045298 tubulin complex(GO:0045298)
0.0 0.2 GO:0008540 proteasome regulatory particle, base subcomplex(GO:0008540)
0.0 0.2 GO:0045239 tricarboxylic acid cycle enzyme complex(GO:0045239)
0.0 0.1 GO:0044613 nuclear pore central transport channel(GO:0044613) Flemming body(GO:0090543)
0.0 0.1 GO:0097427 microtubule bundle(GO:0097427)
0.0 0.1 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.0 0.1 GO:0034750 Scrib-APC-beta-catenin complex(GO:0034750)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 33 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 1.0 GO:0030550 acetylcholine receptor inhibitor activity(GO:0030550)
0.0 1.0 GO:0015175 neutral amino acid transmembrane transporter activity(GO:0015175)
0.1 0.8 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.2 0.7 GO:0023029 peptide antigen-transporting ATPase activity(GO:0015433) MHC class Ib protein binding(GO:0023029) tapasin binding(GO:0046980)
0.0 0.7 GO:0050840 extracellular matrix binding(GO:0050840)
0.0 0.7 GO:0030507 spectrin binding(GO:0030507)
0.1 0.6 GO:0071253 connexin binding(GO:0071253)
0.1 0.6 GO:0008889 glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.0 0.6 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0 0.5 GO:0055106 ubiquitin-protein transferase regulator activity(GO:0055106)
0.0 0.5 GO:0005035 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.0 0.5 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.0 0.5 GO:0050699 WW domain binding(GO:0050699)
0.0 0.4 GO:0070180 large ribosomal subunit rRNA binding(GO:0070180)
0.0 0.4 GO:0017049 GTP-Rho binding(GO:0017049)
0.0 0.4 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706)
0.0 0.4 GO:0008748 N-ethylmaleimide reductase activity(GO:0008748) reduced coenzyme F420 dehydrogenase activity(GO:0043738) sulfur oxygenase reductase activity(GO:0043826) malolactic enzyme activity(GO:0043883) epoxyqueuosine reductase activity(GO:0052693)
0.1 0.3 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
0.0 0.3 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.0 0.3 GO:0001085 RNA polymerase II transcription factor binding(GO:0001085)