Motif ID: Tbp

Z-value: 2.922


Transcription factors associated with Tbp:

Gene SymbolEntrez IDGene Name
Tbp ENSMUSG00000014767.10 Tbp

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Tbpmm10_v2_chr17_+_15499888_154999600.087.8e-01Click!


Activity profile for motif Tbp.

activity profile for motif Tbp


Sorted Z-values histogram for motif Tbp

Sorted Z-values for motif Tbp



Network of associatons between targets according to the STRING database.



First level regulatory network of Tbp

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr18_+_65873478 14.233 ENSMUST00000025395.8
ENSMUST00000173530.1
 Grp

gastrin releasing peptide

chr16_+_91225550 13.731 ENSMUST00000035608.8
 Olig2
oligodendrocyte transcription factor 2
chr8_-_110168204 11.395 ENSMUST00000003754.6
 Calb2
calbindin 2
chr15_+_3270767 10.412 ENSMUST00000082424.4
ENSMUST00000159158.1
ENSMUST00000159216.1
ENSMUST00000160311.1
 Sepp1



selenoprotein P, plasma, 1



chr7_+_35119285 8.304 ENSMUST00000042985.9
 Cebpa
CCAAT/enhancer binding protein (C/EBP), alpha
chr1_-_171196229 8.084 ENSMUST00000111332.1
 Pcp4l1
Purkinje cell protein 4-like 1
chr11_-_102897123 7.578 ENSMUST00000067444.3
 Gfap
glial fibrillary acidic protein
chr8_+_94179089 6.965 ENSMUST00000034215.6
 Mt1
metallothionein 1
chr12_+_85473883 6.839 ENSMUST00000021674.6
 Fos
FBJ osteosarcoma oncogene
chr2_+_152736244 5.972 ENSMUST00000038368.8
ENSMUST00000109824.1
 Id1

inhibitor of DNA binding 1

chr6_-_136875794 5.453 ENSMUST00000032342.1
 Mgp
matrix Gla protein
chr4_+_136143497 5.348 ENSMUST00000008016.2
 Id3
inhibitor of DNA binding 3
chr13_-_23622502 5.195 ENSMUST00000062045.2
 Hist1h1e
histone cluster 1, H1e
chr6_+_90550789 5.144 ENSMUST00000130418.1
ENSMUST00000032175.8
 Aldh1l1

aldehyde dehydrogenase 1 family, member L1

chr11_+_82101836 5.083 ENSMUST00000000194.3
 Ccl12
chemokine (C-C motif) ligand 12
chr8_+_12395287 4.976 ENSMUST00000180353.1
 Sox1
SRY-box containing gene 1
chr13_+_23581563 4.968 ENSMUST00000102968.1
 Hist1h4d
histone cluster 1, H4d
chr17_-_34000257 4.911 ENSMUST00000087189.6
ENSMUST00000173075.1
ENSMUST00000172760.1
ENSMUST00000172912.1
ENSMUST00000025181.10
 H2-K1




histocompatibility 2, K1, K region




chr5_-_77115145 4.879 ENSMUST00000081964.5
 Hopx
HOP homeobox
chr3_-_145649970 4.868 ENSMUST00000029846.3
 Cyr61
cysteine rich protein 61

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 117 entries
Log-likelihood per target Total log-likelihoodTermDescription
4.6 13.7 GO:0021529 spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530)
2.0 12.1 GO:0010624 regulation of Schwann cell proliferation(GO:0010624)
0.3 11.8 GO:0007218 neuropeptide signaling pathway(GO:0007218)
1.4 9.8 GO:0001887 selenium compound metabolic process(GO:0001887)
0.3 9.4 GO:0034723 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
1.4 8.3 GO:0000050 urea cycle(GO:0000050) urea metabolic process(GO:0019627)
0.5 7.7 GO:0035994 response to muscle stretch(GO:0035994)
0.0 7.2 GO:0051480 regulation of cytosolic calcium ion concentration(GO:0051480)
1.0 7.0 GO:0010273 detoxification of copper ion(GO:0010273) cellular response to zinc ion(GO:0071294) stress response to copper ion(GO:1990169)
1.2 6.0 GO:1903026 negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903026)
0.8 5.8 GO:0016584 nucleosome positioning(GO:0016584)
0.2 5.8 GO:0045662 negative regulation of myoblast differentiation(GO:0045662)
1.1 5.6 GO:0044838 cell quiescence(GO:0044838)
1.7 5.1 GO:0042560 10-formyltetrahydrofolate catabolic process(GO:0009258) folic acid-containing compound catabolic process(GO:0009397) pteridine-containing compound catabolic process(GO:0042560)
1.7 5.1 GO:2000501 natural killer cell chemotaxis(GO:0035747) negative regulation of lymphocyte migration(GO:2000402) regulation of natural killer cell chemotaxis(GO:2000501)
0.3 5.0 GO:0021521 ventral spinal cord interneuron specification(GO:0021521) cell fate specification involved in pattern specification(GO:0060573)
1.6 4.9 GO:0003278 apoptotic process involved in heart morphogenesis(GO:0003278)
1.2 4.9 GO:0042360 vitamin E metabolic process(GO:0042360)
0.8 4.9 GO:0042535 positive regulation of tumor necrosis factor biosynthetic process(GO:0042535)
0.8 4.9 GO:0042590 antigen processing and presentation of exogenous peptide antigen via MHC class I(GO:0042590)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 58 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 40.4 GO:0005615 extracellular space(GO:0005615)
0.0 19.6 GO:0005667 transcription factor complex(GO:0005667)
0.2 16.6 GO:0000786 nucleosome(GO:0000786)
0.5 12.2 GO:0005921 gap junction(GO:0005921)
3.0 12.1 GO:0097450 astrocyte end-foot(GO:0097450)
2.8 8.3 GO:0036488 CHOP-C/EBP complex(GO:0036488)
0.1 6.4 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
1.4 5.7 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
1.6 4.9 GO:0097512 cardiac myofibril(GO:0097512)
0.4 4.9 GO:0042612 MHC class I protein complex(GO:0042612)
0.2 4.6 GO:0005782 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.0 4.6 GO:0005764 lytic vacuole(GO:0000323) lysosome(GO:0005764)
0.2 4.2 GO:0002080 acrosomal membrane(GO:0002080)
0.1 3.9 GO:0005680 anaphase-promoting complex(GO:0005680)
0.1 3.7 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.0 3.2 GO:0045211 postsynaptic membrane(GO:0045211)
0.0 3.0 GO:0005802 trans-Golgi network(GO:0005802)
0.4 2.6 GO:0032299 ribonuclease H2 complex(GO:0032299)
0.5 2.3 GO:1990357 terminal web(GO:1990357)
0.7 2.2 GO:0036128 CatSper complex(GO:0036128)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 86 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.7 22.0 GO:0071837 HMG box domain binding(GO:0071837)
0.0 14.5 GO:0005509 calcium ion binding(GO:0005509)
0.7 13.6 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.1 12.2 GO:0005178 integrin binding(GO:0005178)
0.1 10.5 GO:0042393 histone binding(GO:0042393)
0.6 8.6 GO:0008430 selenium binding(GO:0008430)
0.1 8.4 GO:0001046 core promoter sequence-specific DNA binding(GO:0001046)
0.2 7.0 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.2 6.8 GO:0070412 R-SMAD binding(GO:0070412)
0.3 6.0 GO:0070628 proteasome binding(GO:0070628)
1.4 5.7 GO:0031720 haptoglobin binding(GO:0031720)
0.0 5.7 GO:0005516 calmodulin binding(GO:0005516)
0.0 5.7 GO:0003735 structural constituent of ribosome(GO:0003735)
0.1 5.6 GO:0005507 copper ion binding(GO:0005507)
1.7 5.1 GO:0016155 formyltetrahydrofolate dehydrogenase activity(GO:0016155)
1.3 5.1 GO:0031727 CCR2 chemokine receptor binding(GO:0031727)
0.4 4.9 GO:0030881 beta-2-microglobulin binding(GO:0030881)
0.1 4.9 GO:0030291 protein serine/threonine kinase inhibitor activity(GO:0030291)
0.4 4.3 GO:0048018 receptor agonist activity(GO:0048018)
0.7 4.2 GO:0008379 thioredoxin peroxidase activity(GO:0008379)