Motif ID: Tbx15

Z-value: 0.579


Transcription factors associated with Tbx15:

Gene SymbolEntrez IDGene Name
Tbx15 ENSMUSG00000027868.5 Tbx15



Activity profile for motif Tbx15.

activity profile for motif Tbx15


Sorted Z-values histogram for motif Tbx15

Sorted Z-values for motif Tbx15



Network of associatons between targets according to the STRING database.



First level regulatory network of Tbx15

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr4_+_125490688 3.071 ENSMUST00000030676.7
 Grik3
glutamate receptor, ionotropic, kainate 3
chr1_+_153665274 2.734 ENSMUST00000152114.1
ENSMUST00000111812.1
 Rgs8

regulator of G-protein signaling 8

chr1_+_153665666 2.197 ENSMUST00000111814.1
ENSMUST00000111810.1
 Rgs8

regulator of G-protein signaling 8

chr1_+_153665587 1.423 ENSMUST00000147700.1
 Rgs8
regulator of G-protein signaling 8
chr3_+_75557530 1.368 ENSMUST00000161776.1
ENSMUST00000029423.8
 Serpini1

serine (or cysteine) peptidase inhibitor, clade I, member 1

chr1_+_153665627 1.105 ENSMUST00000147482.1
 Rgs8
regulator of G-protein signaling 8
chr2_-_57114970 0.945 ENSMUST00000028166.2
 Nr4a2
nuclear receptor subfamily 4, group A, member 2
chrX_-_52165252 0.934 ENSMUST00000033450.2
 Gpc4
glypican 4
chr1_+_6730051 0.798 ENSMUST00000043578.6
ENSMUST00000131467.1
ENSMUST00000150761.1
ENSMUST00000151281.1
 St18



suppression of tumorigenicity 18



chr18_-_47333311 0.794 ENSMUST00000126684.1
ENSMUST00000156422.1
 Sema6a

sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A

chrX_+_41401304 0.696 ENSMUST00000076349.5
 Gria3
glutamate receptor, ionotropic, AMPA3 (alpha 3)
chr15_-_12592556 0.663 ENSMUST00000075317.5
 Pdzd2
PDZ domain containing 2
chr6_+_61180313 0.656 ENSMUST00000126214.1
 Ccser1
coiled-coil serine rich 1
chr4_-_82505749 0.650 ENSMUST00000107245.2
ENSMUST00000107246.1
 Nfib

nuclear factor I/B

chr8_+_23035116 0.627 ENSMUST00000117296.1
ENSMUST00000141784.2
 Ank1

ankyrin 1, erythroid

chr11_-_84068357 0.585 ENSMUST00000100705.4
 Dusp14
dual specificity phosphatase 14
chrX_+_41401128 0.571 ENSMUST00000115103.2
 Gria3
glutamate receptor, ionotropic, AMPA3 (alpha 3)
chr7_-_75309262 0.567 ENSMUST00000165175.1
 Sv2b
synaptic vesicle glycoprotein 2 b
chr11_-_84068766 0.552 ENSMUST00000018792.5
 Dusp14
dual specificity phosphatase 14
chr1_+_170214826 0.525 ENSMUST00000159201.1
ENSMUST00000055830.1
 4930500M09Rik

RIKEN cDNA 4930500M09 gene


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 107 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.6 7.5 GO:0060159 regulation of dopamine receptor signaling pathway(GO:0060159)
0.3 3.1 GO:0051967 negative regulation of synaptic transmission, glutamatergic(GO:0051967)
0.0 1.3 GO:0001919 regulation of receptor recycling(GO:0001919)
0.0 1.1 GO:0035335 peptidyl-tyrosine dephosphorylation(GO:0035335)
0.2 0.9 GO:0051866 general adaptation syndrome(GO:0051866)
0.0 0.8 GO:2001224 positive regulation of neuron migration(GO:2001224)
0.2 0.7 GO:2000795 negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.1 0.6 GO:0015871 choline transport(GO:0015871)
0.2 0.5 GO:0070844 misfolded protein transport(GO:0070843) polyubiquitinated protein transport(GO:0070844) polyubiquitinated misfolded protein transport(GO:0070845) Hsp90 deacetylation(GO:0070846)
0.1 0.5 GO:0007171 activation of transmembrane receptor protein tyrosine kinase activity(GO:0007171)
0.1 0.5 GO:0061087 positive regulation of histone H3-K27 methylation(GO:0061087)
0.1 0.5 GO:0019227 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.0 0.5 GO:0045671 negative regulation of osteoclast differentiation(GO:0045671)
0.0 0.5 GO:0045653 negative regulation of megakaryocyte differentiation(GO:0045653)
0.0 0.5 GO:0033014 porphyrin-containing compound biosynthetic process(GO:0006779) tetrapyrrole biosynthetic process(GO:0033014)
0.1 0.4 GO:0007621 negative regulation of female receptivity(GO:0007621)
0.1 0.4 GO:0042271 susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.1 0.4 GO:0048686 regulation of sprouting of injured axon(GO:0048686) regulation of axon extension involved in regeneration(GO:0048690)
0.1 0.4 GO:0090325 regulation of locomotion involved in locomotory behavior(GO:0090325) negative regulation of locomotion involved in locomotory behavior(GO:0090327)
0.1 0.4 GO:0099624 regulation of atrial cardiac muscle cell membrane repolarization(GO:0060372) atrial cardiac muscle cell membrane repolarization(GO:0099624)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 28 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 6.9 GO:0032809 neuronal cell body membrane(GO:0032809)
0.1 3.0 GO:0032839 dendrite cytoplasm(GO:0032839)
0.1 1.8 GO:0030673 axolemma(GO:0030673)
0.1 1.3 GO:0043083 synaptic cleft(GO:0043083)
0.1 0.7 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.0 0.5 GO:0034707 chloride channel complex(GO:0034707)
0.0 0.5 GO:0035869 ciliary transition zone(GO:0035869)
0.0 0.5 GO:0016235 aggresome(GO:0016235)
0.0 0.4 GO:0070852 cell body fiber(GO:0070852)
0.0 0.4 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.3 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.0 0.3 GO:0070545 PeBoW complex(GO:0070545)
0.0 0.3 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 0.3 GO:0060077 inhibitory synapse(GO:0060077)
0.1 0.2 GO:0030868 smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425)
0.0 0.2 GO:1990357 terminal web(GO:1990357)
0.0 0.2 GO:0030893 meiotic cohesin complex(GO:0030893)
0.0 0.2 GO:0005677 chromatin silencing complex(GO:0005677)
0.0 0.2 GO:0061700 GATOR2 complex(GO:0061700)
0.0 0.2 GO:0031209 SCAR complex(GO:0031209)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 62 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 7.5 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.6 3.1 GO:0001640 adenylate cyclase inhibiting G-protein coupled glutamate receptor activity(GO:0001640)
0.0 1.5 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.2 1.0 GO:0004971 AMPA glutamate receptor activity(GO:0004971)
0.0 1.0 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 0.9 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.2 0.8 GO:0016941 natriuretic peptide receptor activity(GO:0016941)
0.1 0.8 GO:0005004 GPI-linked ephrin receptor activity(GO:0005004)
0.0 0.8 GO:0030215 semaphorin receptor binding(GO:0030215)
0.1 0.7 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.0 0.7 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.0 0.7 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.1 0.6 GO:0015220 choline transmembrane transporter activity(GO:0015220)
0.0 0.6 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.1 0.5 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.1 0.5 GO:0042903 tubulin deacetylase activity(GO:0042903)
0.0 0.5 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.1 0.4 GO:0031752 D3 dopamine receptor binding(GO:0031750) D5 dopamine receptor binding(GO:0031752)
0.1 0.4 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.1 0.4 GO:0036033 mediator complex binding(GO:0036033)