Motif ID: Tbx19

Z-value: 1.266


Transcription factors associated with Tbx19:

Gene SymbolEntrez IDGene Name
Tbx19 ENSMUSG00000026572.5 Tbx19



Activity profile for motif Tbx19.

activity profile for motif Tbx19


Sorted Z-values histogram for motif Tbx19

Sorted Z-values for motif Tbx19



Network of associatons between targets according to the STRING database.



First level regulatory network of Tbx19

PNG image of the network

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Top targets:


Showing 1 to 20 of 108 entries
PromoterScoreRefseqGene SymbolGene Name
chr2_-_113758638 3.793 ENSMUST00000099575.3
 Grem1
gremlin 1
chrY_+_897782 3.498 ENSMUST00000055032.7
 Kdm5d
lysine (K)-specific demethylase 5D
chr11_-_120731944 3.001 ENSMUST00000154565.1
ENSMUST00000026148.2
 Cbr2

carbonyl reductase 2

chr6_-_119467210 2.955 ENSMUST00000118120.1
 Wnt5b
wingless-related MMTV integration site 5B
chr18_-_82406777 2.931 ENSMUST00000065224.6
 Galr1
galanin receptor 1
chr17_-_35027909 2.726 ENSMUST00000040151.2
 Sapcd1
suppressor APC domain containing 1
chr19_-_3414464 2.254 ENSMUST00000025842.6
 Gal
galanin
chr14_+_115042752 2.230 ENSMUST00000134140.2
 Mir17hg
Mir17 host gene 1 (non-protein coding)
chr11_+_101468164 2.167 ENSMUST00000001347.6
 Rnd2
Rho family GTPase 2
chr5_-_92278155 2.022 ENSMUST00000159345.1
ENSMUST00000113102.3
 Naaa

N-acylethanolamine acid amidase

chr6_+_90465287 2.006 ENSMUST00000113530.1
 Klf15
Kruppel-like factor 15
chr14_-_66124482 1.799 ENSMUST00000070515.1
 Ephx2
epoxide hydrolase 2, cytoplasmic
chr19_+_5474681 1.774 ENSMUST00000165485.1
ENSMUST00000166253.1
ENSMUST00000167371.1
ENSMUST00000167855.1
ENSMUST00000070118.7
 Efemp2




epidermal growth factor-containing fibulin-like extracellular matrix protein 2




chr11_-_101171302 1.754 ENSMUST00000164474.1
ENSMUST00000043397.7
 Plekhh3

pleckstrin homology domain containing, family H (with MyTH4 domain) member 3

chr7_+_130936172 1.685 ENSMUST00000006367.7
 Htra1
HtrA serine peptidase 1
chr11_-_60046477 1.670 ENSMUST00000000310.7
ENSMUST00000102693.2
ENSMUST00000148512.1
 Pemt


phosphatidylethanolamine N-methyltransferase


chr9_-_21760275 1.527 ENSMUST00000098942.4
 Spc24
SPC24, NDC80 kinetochore complex component, homolog (S. cerevisiae)
chrM_+_10167 1.456 ENSMUST00000082414.1
 mt-Nd4
mitochondrially encoded NADH dehydrogenase 4
chr6_+_17749170 1.445 ENSMUST00000053148.7
ENSMUST00000115417.3
 St7

suppression of tumorigenicity 7

chr5_+_96173940 1.408 ENSMUST00000048361.8
 Gm2840
predicted gene 2840

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 45 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.7 5.2 GO:0051464 positive regulation of cortisol secretion(GO:0051464)
1.3 3.8 GO:1901228 regulation of osteoclast proliferation(GO:0090289) negative regulation of bone mineralization involved in bone maturation(GO:1900158) positive regulation of transcription from RNA polymerase II promoter involved in heart development(GO:1901228)
0.7 3.5 GO:0002457 T cell antigen processing and presentation(GO:0002457)
1.0 3.0 GO:0006116 NADH oxidation(GO:0006116)
0.1 3.0 GO:0045600 positive regulation of fat cell differentiation(GO:0045600)
0.2 2.2 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
0.1 2.0 GO:0072010 renal filtration cell differentiation(GO:0061318) glomerular epithelium development(GO:0072010) glomerular visceral epithelial cell differentiation(GO:0072112) glomerular epithelial cell differentiation(GO:0072311)
0.6 1.8 GO:0002538 arachidonic acid metabolite production involved in inflammatory response(GO:0002538) olefin metabolic process(GO:1900673)
0.3 1.7 GO:0050747 positive regulation of lipoprotein metabolic process(GO:0050747)
0.3 1.7 GO:0060718 chorionic trophoblast cell differentiation(GO:0060718)
0.1 1.5 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.0 1.3 GO:0000266 mitochondrial fission(GO:0000266)
0.0 1.2 GO:0042773 ATP synthesis coupled electron transport(GO:0042773)
0.2 1.1 GO:0042270 protection from natural killer cell mediated cytotoxicity(GO:0042270)
0.1 0.9 GO:0045741 positive regulation of epidermal growth factor-activated receptor activity(GO:0045741)
0.1 0.7 GO:0002677 negative regulation of chronic inflammatory response(GO:0002677)
0.0 0.7 GO:0046597 negative regulation of viral entry into host cell(GO:0046597)
0.0 0.7 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.1 0.6 GO:0048304 positive regulation of isotype switching to IgG isotypes(GO:0048304)
0.1 0.6 GO:0016081 synaptic vesicle docking(GO:0016081)

Gene overrepresentation in cellular_component category:

Showing 1 to 17 of 17 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 12.0 GO:0005615 extracellular space(GO:0005615)
0.0 2.7 GO:0070469 respiratory chain(GO:0070469)
0.0 2.3 GO:0005777 peroxisome(GO:0005777) microbody(GO:0042579)
0.0 2.1 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.3 1.5 GO:0031262 Ndc80 complex(GO:0031262)
0.0 1.3 GO:0031526 brush border membrane(GO:0031526)
0.2 0.8 GO:0005784 Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
0.0 0.8 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.1 0.6 GO:1990796 photoreceptor cell terminal bouton(GO:1990796)
0.0 0.6 GO:0000788 nuclear nucleosome(GO:0000788)
0.0 0.6 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.1 0.4 GO:0097361 CIA complex(GO:0097361)
0.0 0.4 GO:0001739 sex chromatin(GO:0001739)
0.0 0.3 GO:0097433 dense body(GO:0097433)
0.0 0.3 GO:0060091 kinocilium(GO:0060091)
0.1 0.2 GO:0070557 PCNA-p21 complex(GO:0070557)
0.0 0.2 GO:0033093 multivesicular body membrane(GO:0032585) Weibel-Palade body(GO:0033093)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 29 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.7 5.2 GO:0004966 galanin receptor activity(GO:0004966)
0.4 3.8 GO:0043184 vascular endothelial growth factor receptor 2 binding(GO:0043184)
0.5 3.5 GO:0032453 histone demethylase activity (H3-K4 specific)(GO:0032453)
0.8 3.0 GO:0004090 carbonyl reductase (NADPH) activity(GO:0004090)
0.1 3.0 GO:0005109 frizzled binding(GO:0005109)
0.1 2.7 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.1 2.5 GO:0043747 protein-N-terminal asparagine amidohydrolase activity(GO:0008418) UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity(GO:0008759) iprodione amidohydrolase activity(GO:0018748) (3,5-dichlorophenylurea)acetate amidohydrolase activity(GO:0018749) 4'-(2-hydroxyisopropyl)phenylurea amidohydrolase activity(GO:0034571) didemethylisoproturon amidohydrolase activity(GO:0034573) N-isopropylacetanilide amidohydrolase activity(GO:0034576) N-cyclohexylformamide amidohydrolase activity(GO:0034781) isonicotinic acid hydrazide hydrolase activity(GO:0034876) cis-aconitamide amidase activity(GO:0034882) gamma-N-formylaminovinylacetate hydrolase activity(GO:0034885) N2-acetyl-L-lysine deacetylase activity(GO:0043747) O-succinylbenzoate synthase activity(GO:0043748) indoleacetamide hydrolase activity(GO:0043864) N-acetylcitrulline deacetylase activity(GO:0043909) N-acetylgalactosamine-6-phosphate deacetylase activity(GO:0047419) diacetylchitobiose deacetylase activity(GO:0052773) chitooligosaccharide deacetylase activity(GO:0052790)
0.3 1.8 GO:0004301 epoxide hydrolase activity(GO:0004301)
0.2 1.7 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.1 1.7 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.1 1.4 GO:0008430 selenium binding(GO:0008430)
0.1 1.1 GO:0046703 natural killer cell lectin-like receptor binding(GO:0046703)
0.2 0.9 GO:1990932 5.8S rRNA binding(GO:1990932)
0.0 0.9 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.1 0.7 GO:0070330 aromatase activity(GO:0070330)
0.1 0.6 GO:0050544 arachidonic acid binding(GO:0050544)
0.0 0.5 GO:0003988 acetyl-CoA C-acyltransferase activity(GO:0003988)
0.0 0.5 GO:0097472 cyclin-dependent protein serine/threonine kinase activity(GO:0004693) cyclin-dependent protein kinase activity(GO:0097472)
0.1 0.4 GO:0004449 isocitrate dehydrogenase (NAD+) activity(GO:0004449)
0.1 0.4 GO:0015143 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)