Motif ID: Tbx1_Eomes
Z-value: 1.345
Transcription factors associated with Tbx1_Eomes:
| Gene Symbol | Entrez ID | Gene Name |
|---|---|---|
| Eomes | ENSMUSG00000032446.8 | Eomes |
| Tbx1 | ENSMUSG00000009097.9 | Tbx1 |
Activity-expression correlation:
| Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| Eomes | mm10_v2_chr9_+_118478851_118478866 | 0.89 | 2.0e-05 | Click! |
Top targets:
Showing 1 to 20 of 143 entries
Gene overrepresentation in biological_process category:
Showing 1 to 20 of 67 entries
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 2.0 | 22.3 | GO:0051967 | negative regulation of synaptic transmission, glutamatergic(GO:0051967) |
| 1.6 | 19.3 | GO:0060159 | regulation of dopamine receptor signaling pathway(GO:0060159) |
| 0.2 | 10.3 | GO:0001919 | regulation of receptor recycling(GO:0001919) |
| 2.4 | 9.6 | GO:0051866 | general adaptation syndrome(GO:0051866) |
| 0.2 | 6.8 | GO:0035335 | peptidyl-tyrosine dephosphorylation(GO:0035335) |
| 0.0 | 6.2 | GO:0050807 | regulation of synapse organization(GO:0050807) |
| 0.5 | 5.9 | GO:0060501 | positive regulation of epithelial cell proliferation involved in lung morphogenesis(GO:0060501) |
| 0.6 | 4.0 | GO:0034047 | regulation of protein phosphatase type 2A activity(GO:0034047) |
| 0.9 | 2.8 | GO:0007621 | negative regulation of female receptivity(GO:0007621) |
| 0.0 | 2.6 | GO:0008347 | glial cell migration(GO:0008347) |
| 0.8 | 2.4 | GO:0042663 | regulation of endodermal cell fate specification(GO:0042663) |
| 0.8 | 2.3 | GO:0070973 | protein localization to endoplasmic reticulum exit site(GO:0070973) |
| 0.0 | 2.0 | GO:0060612 | adipose tissue development(GO:0060612) |
| 0.1 | 1.9 | GO:0042149 | cellular response to glucose starvation(GO:0042149) |
| 0.3 | 1.7 | GO:0046549 | retinal cone cell development(GO:0046549) |
| 0.5 | 1.6 | GO:0003219 | cardiac right ventricle formation(GO:0003219) |
| 0.1 | 1.6 | GO:0003334 | keratinocyte development(GO:0003334) |
| 0.5 | 1.4 | GO:0007386 | compartment pattern specification(GO:0007386) |
| 0.4 | 1.3 | GO:0014005 | microglia differentiation(GO:0014004) microglia development(GO:0014005) |
| 0.3 | 1.3 | GO:0035616 | histone H2B conserved C-terminal lysine deubiquitination(GO:0035616) |
Gene overrepresentation in cellular_component category:
Showing 1 to 20 of 22 entries
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.6 | 21.3 | GO:0032839 | dendrite cytoplasm(GO:0032839) |
| 0.5 | 19.3 | GO:0032809 | neuronal cell body membrane(GO:0032809) |
| 0.9 | 10.3 | GO:0043083 | synaptic cleft(GO:0043083) |
| 0.1 | 6.1 | GO:0005581 | collagen trimer(GO:0005581) |
| 0.2 | 4.0 | GO:0000159 | protein phosphatase type 2A complex(GO:0000159) |
| 0.0 | 2.0 | GO:0005905 | clathrin-coated pit(GO:0005905) |
| 0.1 | 1.6 | GO:0071564 | npBAF complex(GO:0071564) |
| 0.0 | 1.3 | GO:0060077 | inhibitory synapse(GO:0060077) |
| 0.1 | 1.2 | GO:0044300 | cerebellar mossy fiber(GO:0044300) |
| 0.0 | 1.2 | GO:0034707 | chloride channel complex(GO:0034707) |
| 0.1 | 0.9 | GO:0008074 | guanylate cyclase complex, soluble(GO:0008074) |
| 0.0 | 0.8 | GO:0030673 | axolemma(GO:0030673) |
| 0.0 | 0.8 | GO:0031201 | SNARE complex(GO:0031201) |
| 0.1 | 0.6 | GO:0061700 | GATOR2 complex(GO:0061700) |
| 0.0 | 0.6 | GO:0043034 | costamere(GO:0043034) |
| 0.0 | 0.3 | GO:0071818 | BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379) |
| 0.1 | 0.2 | GO:0005785 | signal recognition particle receptor complex(GO:0005785) |
| 0.0 | 0.2 | GO:0030893 | meiotic cohesin complex(GO:0030893) |
| 0.0 | 0.2 | GO:0042629 | mast cell granule(GO:0042629) |
| 0.0 | 0.1 | GO:0000439 | core TFIIH complex(GO:0000439) |
Gene overrepresentation in molecular_function category:
Showing 1 to 20 of 45 entries
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 4.5 | 22.3 | GO:0001640 | adenylate cyclase inhibiting G-protein coupled glutamate receptor activity(GO:0001640) |
| 0.5 | 19.3 | GO:0001965 | G-protein alpha-subunit binding(GO:0001965) |
| 1.5 | 10.3 | GO:0004971 | AMPA glutamate receptor activity(GO:0004971) |
| 0.3 | 9.3 | GO:0017017 | MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017) |
| 0.3 | 8.7 | GO:0035259 | glucocorticoid receptor binding(GO:0035259) |
| 0.3 | 4.0 | GO:0008601 | protein phosphatase type 2A regulator activity(GO:0008601) |
| 0.2 | 3.0 | GO:0005540 | hyaluronic acid binding(GO:0005540) |
| 0.9 | 2.8 | GO:0031752 | D3 dopamine receptor binding(GO:0031750) D5 dopamine receptor binding(GO:0031752) |
| 0.2 | 1.9 | GO:0050291 | sphingosine N-acyltransferase activity(GO:0050291) |
| 0.4 | 1.8 | GO:0016941 | natriuretic peptide receptor activity(GO:0016941) |
| 0.6 | 1.7 | GO:0008502 | melatonin receptor activity(GO:0008502) |
| 0.1 | 1.6 | GO:0016922 | ligand-dependent nuclear receptor binding(GO:0016922) |
| 0.0 | 1.6 | GO:0008565 | protein transporter activity(GO:0008565) |
| 0.1 | 1.4 | GO:0005112 | Notch binding(GO:0005112) |
| 0.0 | 1.4 | GO:0008748 | N-ethylmaleimide reductase activity(GO:0008748) reduced coenzyme F420 dehydrogenase activity(GO:0043738) sulfur oxygenase reductase activity(GO:0043826) malolactic enzyme activity(GO:0043883) epoxyqueuosine reductase activity(GO:0052693) |
| 0.4 | 1.2 | GO:0008515 | sucrose:proton symporter activity(GO:0008506) sucrose transmembrane transporter activity(GO:0008515) disaccharide transmembrane transporter activity(GO:0015154) oligosaccharide transmembrane transporter activity(GO:0015157) |
| 0.1 | 1.2 | GO:0005247 | voltage-gated chloride channel activity(GO:0005247) |
| 0.0 | 1.2 | GO:0001106 | RNA polymerase II transcription corepressor activity(GO:0001106) |
| 0.0 | 1.1 | GO:0019905 | syntaxin binding(GO:0019905) |
| 0.3 | 1.0 | GO:0015220 | choline transmembrane transporter activity(GO:0015220) |
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