Motif ID: Tbx2
Z-value: 1.185
Transcription factors associated with Tbx2:
Gene Symbol | Entrez ID | Gene Name |
---|---|---|
Tbx2 | ENSMUSG00000000093.6 | Tbx2 |
Activity-expression correlation:
Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
---|---|---|---|---|
Tbx2 | mm10_v2_chr11_+_85832551_85832551 | -0.07 | 8.2e-01 | Click! |
Top targets:
Gene overrepresentation in biological_process category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
1.3 | 3.9 | GO:0014005 | microglia differentiation(GO:0014004) microglia development(GO:0014005) |
0.6 | 1.9 | GO:0045110 | intermediate filament bundle assembly(GO:0045110) |
0.6 | 1.9 | GO:1902277 | negative regulation of pancreatic amylase secretion(GO:1902277) |
0.5 | 5.9 | GO:0051967 | negative regulation of synaptic transmission, glutamatergic(GO:0051967) |
0.5 | 1.4 | GO:0033364 | endosome to lysosome transport via multivesicular body sorting pathway(GO:0032510) mast cell secretory granule organization(GO:0033364) |
0.5 | 1.4 | GO:0015772 | disaccharide transport(GO:0015766) sucrose transport(GO:0015770) oligosaccharide transport(GO:0015772) |
0.4 | 1.3 | GO:0070973 | protein localization to endoplasmic reticulum exit site(GO:0070973) |
0.4 | 2.2 | GO:0060467 | negative regulation of fertilization(GO:0060467) |
0.3 | 1.4 | GO:1901894 | regulation of calcium-transporting ATPase activity(GO:1901894) |
0.3 | 0.8 | GO:0036118 | hyaluranon cable assembly(GO:0036118) regulation of hyaluranon cable assembly(GO:1900104) positive regulation of hyaluranon cable assembly(GO:1900106) |
0.3 | 1.3 | GO:0030240 | skeletal muscle thin filament assembly(GO:0030240) |
0.2 | 0.7 | GO:0001928 | regulation of exocyst assembly(GO:0001928) |
0.2 | 0.6 | GO:0071336 | lung growth(GO:0060437) positive regulation of fat cell proliferation(GO:0070346) regulation of hair follicle cell proliferation(GO:0071336) positive regulation of hair follicle cell proliferation(GO:0071338) |
0.2 | 7.6 | GO:0043551 | regulation of phosphatidylinositol 3-kinase activity(GO:0043551) |
0.2 | 0.8 | GO:0015959 | diadenosine polyphosphate metabolic process(GO:0015959) |
0.2 | 0.5 | GO:1900365 | positive regulation of mRNA polyadenylation(GO:1900365) |
0.2 | 1.6 | GO:0060501 | positive regulation of epithelial cell proliferation involved in lung morphogenesis(GO:0060501) |
0.1 | 0.7 | GO:0061086 | negative regulation of histone H3-K27 methylation(GO:0061086) |
0.1 | 1.3 | GO:0098907 | protein localization to M-band(GO:0036309) protein localization to T-tubule(GO:0036371) regulation of SA node cell action potential(GO:0098907) |
0.1 | 2.4 | GO:0003334 | keratinocyte development(GO:0003334) |
0.1 | 0.8 | GO:2001012 | mesenchymal cell differentiation involved in kidney development(GO:0072161) mesenchymal cell differentiation involved in renal system development(GO:2001012) |
0.1 | 3.8 | GO:0035335 | peptidyl-tyrosine dephosphorylation(GO:0035335) |
0.1 | 0.4 | GO:0090327 | negative regulation of locomotion involved in locomotory behavior(GO:0090327) |
0.1 | 0.3 | GO:0001580 | detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580) |
0.1 | 0.5 | GO:1904565 | response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904565) cellular response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904566) |
0.1 | 3.9 | GO:0036075 | endochondral ossification(GO:0001958) replacement ossification(GO:0036075) |
0.1 | 0.3 | GO:0034729 | histone H3-K79 methylation(GO:0034729) |
0.1 | 1.0 | GO:2001256 | regulation of store-operated calcium entry(GO:2001256) |
0.1 | 1.3 | GO:0050910 | detection of mechanical stimulus involved in sensory perception of sound(GO:0050910) |
0.1 | 0.3 | GO:0019355 | nicotinamide nucleotide biosynthetic process from aspartate(GO:0019355) 'de novo' NAD biosynthetic process(GO:0034627) 'de novo' NAD biosynthetic process from aspartate(GO:0034628) |
0.1 | 0.4 | GO:0015871 | choline transport(GO:0015871) |
0.1 | 0.7 | GO:0035095 | behavioral response to nicotine(GO:0035095) |
0.1 | 2.0 | GO:0010107 | potassium ion import(GO:0010107) |
0.1 | 0.6 | GO:0030206 | chondroitin sulfate biosynthetic process(GO:0030206) |
0.1 | 0.7 | GO:0032000 | positive regulation of fatty acid beta-oxidation(GO:0032000) |
0.1 | 2.0 | GO:0030866 | cortical actin cytoskeleton organization(GO:0030866) |
0.1 | 1.7 | GO:0042149 | cellular response to glucose starvation(GO:0042149) |
0.0 | 1.2 | GO:0014912 | negative regulation of smooth muscle cell migration(GO:0014912) |
0.0 | 2.1 | GO:0046513 | ceramide biosynthetic process(GO:0046513) |
0.0 | 0.2 | GO:0032929 | negative regulation of superoxide anion generation(GO:0032929) |
0.0 | 0.2 | GO:1903377 | negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903377) |
0.0 | 1.4 | GO:2001222 | regulation of neuron migration(GO:2001222) |
0.0 | 0.2 | GO:0007386 | compartment pattern specification(GO:0007386) |
0.0 | 0.2 | GO:0042730 | fibrinolysis(GO:0042730) |
0.0 | 0.1 | GO:0071947 | protein deubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0071947) |
0.0 | 0.1 | GO:0035262 | gonad morphogenesis(GO:0035262) |
0.0 | 0.8 | GO:0061003 | positive regulation of dendritic spine morphogenesis(GO:0061003) |
0.0 | 0.1 | GO:0021780 | oligodendrocyte cell fate specification(GO:0021778) oligodendrocyte cell fate commitment(GO:0021779) glial cell fate specification(GO:0021780) |
0.0 | 0.0 | GO:1902219 | regulation of intrinsic apoptotic signaling pathway in response to osmotic stress(GO:1902218) negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress(GO:1902219) |
0.0 | 0.6 | GO:0006378 | mRNA polyadenylation(GO:0006378) |
0.0 | 0.1 | GO:0019227 | neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870) |
0.0 | 1.7 | GO:0035023 | regulation of Rho protein signal transduction(GO:0035023) |
Gene overrepresentation in cellular_component category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.6 | 1.9 | GO:0033596 | TSC1-TSC2 complex(GO:0033596) |
0.3 | 6.9 | GO:0005942 | phosphatidylinositol 3-kinase complex(GO:0005942) |
0.3 | 1.0 | GO:0002141 | stereocilia ankle link(GO:0002141) |
0.2 | 5.9 | GO:0032839 | dendrite cytoplasm(GO:0032839) |
0.1 | 1.4 | GO:0033017 | sarcoplasmic reticulum membrane(GO:0033017) |
0.1 | 2.3 | GO:0043034 | costamere(GO:0043034) |
0.1 | 0.7 | GO:0005892 | acetylcholine-gated channel complex(GO:0005892) |
0.0 | 0.7 | GO:0032593 | insulin-responsive compartment(GO:0032593) |
0.0 | 0.3 | GO:0016593 | Cdc73/Paf1 complex(GO:0016593) |
0.0 | 1.0 | GO:0043194 | axon initial segment(GO:0043194) |
0.0 | 0.7 | GO:0035098 | ESC/E(Z) complex(GO:0035098) |
0.0 | 0.5 | GO:1990124 | messenger ribonucleoprotein complex(GO:1990124) |
0.0 | 0.7 | GO:0071565 | nBAF complex(GO:0071565) |
0.0 | 0.2 | GO:0042382 | paraspeckles(GO:0042382) |
0.0 | 2.2 | GO:0001669 | acrosomal vesicle(GO:0001669) |
0.0 | 0.2 | GO:0031362 | anchored component of external side of plasma membrane(GO:0031362) |
0.0 | 5.0 | GO:0043209 | myelin sheath(GO:0043209) |
0.0 | 0.9 | GO:0016328 | lateral plasma membrane(GO:0016328) |
0.0 | 1.3 | GO:0072562 | blood microparticle(GO:0072562) |
0.0 | 0.8 | GO:0010494 | cytoplasmic stress granule(GO:0010494) |
Gene overrepresentation in molecular_function category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
1.2 | 5.9 | GO:0001640 | adenylate cyclase inhibiting G-protein coupled glutamate receptor activity(GO:0001640) |
1.0 | 6.9 | GO:0046935 | 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935) |
0.5 | 1.4 | GO:0008515 | sucrose:proton symporter activity(GO:0008506) sucrose transmembrane transporter activity(GO:0008515) disaccharide transmembrane transporter activity(GO:0015154) oligosaccharide transmembrane transporter activity(GO:0015157) |
0.4 | 4.0 | GO:0050291 | sphingosine N-acyltransferase activity(GO:0050291) |
0.4 | 2.0 | GO:0015467 | G-protein activated inward rectifier potassium channel activity(GO:0015467) |
0.3 | 0.8 | GO:0050501 | hyaluronan synthase activity(GO:0050501) |
0.3 | 0.8 | GO:0047710 | bis(5'-adenosyl)-triphosphatase activity(GO:0047710) |
0.2 | 0.7 | GO:0036313 | phosphatidylinositol 3-kinase catalytic subunit binding(GO:0036313) |
0.2 | 0.6 | GO:0005111 | type 2 fibroblast growth factor receptor binding(GO:0005111) |
0.1 | 1.0 | GO:0031802 | type 5 metabotropic glutamate receptor binding(GO:0031802) |
0.1 | 3.8 | GO:0017017 | MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017) |
0.1 | 2.2 | GO:0004385 | guanylate kinase activity(GO:0004385) |
0.1 | 0.4 | GO:0015220 | choline transmembrane transporter activity(GO:0015220) |
0.1 | 0.6 | GO:0004652 | polynucleotide adenylyltransferase activity(GO:0004652) |
0.1 | 0.6 | GO:0032184 | SUMO polymer binding(GO:0032184) |
0.1 | 0.3 | GO:0004515 | nicotinamide-nucleotide adenylyltransferase activity(GO:0000309) nicotinate-nucleotide adenylyltransferase activity(GO:0004515) |
0.1 | 1.9 | GO:0043274 | phospholipase binding(GO:0043274) |
0.1 | 0.5 | GO:0035727 | lysophosphatidic acid binding(GO:0035727) lysophosphatidic acid receptor activity(GO:0070915) |
0.1 | 0.6 | GO:0015165 | pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165) |
0.1 | 0.7 | GO:0004889 | acetylcholine-activated cation-selective channel activity(GO:0004889) |
0.1 | 0.2 | GO:0030292 | protein tyrosine kinase inhibitor activity(GO:0030292) |
0.0 | 2.2 | GO:0004867 | serine-type endopeptidase inhibitor activity(GO:0004867) |
0.0 | 1.9 | GO:0017112 | Rab guanyl-nucleotide exchange factor activity(GO:0017112) |
0.0 | 0.5 | GO:0035925 | mRNA 3'-UTR AU-rich region binding(GO:0035925) |
0.0 | 1.3 | GO:0008093 | cytoskeletal adaptor activity(GO:0008093) |
0.0 | 2.7 | GO:0004252 | serine-type endopeptidase activity(GO:0004252) |
0.0 | 0.7 | GO:0030275 | LRR domain binding(GO:0030275) |
0.0 | 1.2 | GO:0030215 | semaphorin receptor binding(GO:0030215) |
0.0 | 0.2 | GO:0003993 | acid phosphatase activity(GO:0003993) |
0.0 | 0.1 | GO:1990380 | Lys48-specific deubiquitinase activity(GO:1990380) |
0.0 | 1.7 | GO:0005089 | Rho guanyl-nucleotide exchange factor activity(GO:0005089) |
0.0 | 2.0 | GO:0017048 | Rho GTPase binding(GO:0017048) |
0.0 | 0.4 | GO:0031690 | adrenergic receptor binding(GO:0031690) |
0.0 | 0.0 | GO:0005128 | erythropoietin receptor binding(GO:0005128) |
0.0 | 0.3 | GO:0000993 | RNA polymerase II core binding(GO:0000993) |
0.0 | 0.7 | GO:0005546 | phosphatidylinositol-4,5-bisphosphate binding(GO:0005546) |
0.0 | 0.2 | GO:0070888 | E-box binding(GO:0070888) |
0.0 | 1.6 | GO:0001078 | transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078) |
0.0 | 0.7 | GO:0035064 | methylated histone binding(GO:0035064) |