Motif ID: Tbx3

Z-value: 0.482


Transcription factors associated with Tbx3:

Gene SymbolEntrez IDGene Name
Tbx3 ENSMUSG00000018604.12 Tbx3



Activity profile for motif Tbx3.

activity profile for motif Tbx3


Sorted Z-values histogram for motif Tbx3

Sorted Z-values for motif Tbx3



Network of associatons between targets according to the STRING database.



Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr10_+_127514939 1.346 ENSMUST00000035735.9
Ndufa4l2
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4-like 2
chr11_-_100970887 1.335 ENSMUST00000060792.5
Ptrf
polymerase I and transcript release factor
chr19_+_7056731 0.901 ENSMUST00000040261.5
Macrod1
MACRO domain containing 1
chr7_-_4522427 0.812 ENSMUST00000098859.3
Tnni3
troponin I, cardiac 3
chr7_+_112374839 0.751 ENSMUST00000106645.1
Micalcl
MICAL C-terminal like
chr10_+_56377300 0.682 ENSMUST00000068581.7
Gja1
gap junction protein, alpha 1
chr7_+_107567445 0.662 ENSMUST00000120990.1
Olfml1
olfactomedin-like 1
chr11_-_94507337 0.510 ENSMUST00000040692.8
Mycbpap
MYCBP associated protein
chr7_-_4522794 0.504 ENSMUST00000140424.1
Tnni3
troponin I, cardiac 3
chr14_+_67745229 0.433 ENSMUST00000111095.2
Gnrh1
gonadotropin releasing hormone 1
chr1_+_93215899 0.298 ENSMUST00000138595.1
E030010N08Rik
RIKEN cDNA E030010N08 gene
chr5_-_106926245 0.230 ENSMUST00000117588.1
Hfm1
HFM1, ATP-dependent DNA helicase homolog (S. cerevisiae)
chr17_-_59013264 0.174 ENSMUST00000174122.1
ENSMUST00000025065.5
Nudt12

nudix (nucleoside diphosphate linked moiety X)-type motif 12

chr12_+_84361636 0.119 ENSMUST00000110276.1
Coq6
coenzyme Q6 homolog (yeast)
chr12_+_84362029 0.109 ENSMUST00000110278.1
ENSMUST00000145522.1
Coq6

coenzyme Q6 homolog (yeast)

chr18_-_23981555 0.109 ENSMUST00000115829.1
Zscan30
zinc finger and SCAN domain containing 30
chr7_-_118443549 0.107 ENSMUST00000081574.4
Syt17
synaptotagmin XVII
chrX_-_20931520 0.086 ENSMUST00000001156.7
Cfp
complement factor properdin
chr6_-_97060407 0.064 ENSMUST00000089295.4
Fam19a4
family with sequence similarity 19, member A4
chr12_+_84361968 0.055 ENSMUST00000021661.6
Coq6
coenzyme Q6 homolog (yeast)
chr4_+_135759705 0.011 ENSMUST00000105854.1
Myom3
myomesin family, member 3

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0003104 positive regulation of glomerular filtration(GO:0003104) cell communication by chemical coupling(GO:0010643)
0.2 0.9 GO:0051725 protein de-ADP-ribosylation(GO:0051725)
0.2 1.3 GO:0001980 regulation of systemic arterial blood pressure by ischemic conditions(GO:0001980)
0.2 1.3 GO:0006361 transcription initiation from RNA polymerase I promoter(GO:0006361) termination of RNA polymerase I transcription(GO:0006363)
0.1 0.4 GO:0033087 negative regulation of immature T cell proliferation(GO:0033087)
0.0 0.2 GO:0006742 NADP catabolic process(GO:0006742) pyridine nucleotide catabolic process(GO:0019364)
0.0 0.2 GO:0000712 resolution of meiotic recombination intermediates(GO:0000712)
0.0 0.3 GO:0006744 ubiquinone biosynthetic process(GO:0006744)
0.0 0.1 GO:0006957 complement activation, alternative pathway(GO:0006957)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.3 GO:0005861 troponin complex(GO:0005861)
0.1 0.7 GO:0005916 fascia adherens(GO:0005916)
0.1 0.4 GO:0098554 cytoplasmic side of endoplasmic reticulum membrane(GO:0098554)
0.0 1.3 GO:0005901 caveola(GO:0005901)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.3 GO:0030172 troponin C binding(GO:0030172)
0.2 1.3 GO:0042134 rRNA primary transcript binding(GO:0042134)
0.1 0.7 GO:0071253 connexin binding(GO:0071253)
0.1 0.9 GO:0070636 single-strand selective uracil DNA N-glycosylase activity(GO:0017065) nicotinamide riboside hydrolase activity(GO:0070635) nicotinic acid riboside hydrolase activity(GO:0070636) deoxyribonucleoside 5'-monophosphate N-glycosidase activity(GO:0070694)
0.0 0.3 GO:0052872 3-(3-hydroxyphenyl)propionate hydroxylase activity(GO:0008688) 4-chlorobenzaldehyde oxidase activity(GO:0018471) 3,5-xylenol methylhydroxylase activity(GO:0018630) phenylacetate hydroxylase activity(GO:0018631) 4-nitrophenol 4-monooxygenase activity(GO:0018632) dimethyl sulfide monooxygenase activity(GO:0018633) alpha-pinene monooxygenase [NADH] activity(GO:0018634) phenanthrene 9,10-monooxygenase activity(GO:0018636) 1-hydroxy-2-naphthoate hydroxylase activity(GO:0018637) toluene 4-monooxygenase activity(GO:0018638) xylene monooxygenase activity(GO:0018639) dibenzothiophene monooxygenase activity(GO:0018640) 6-hydroxy-3-methyl-2-oxo-1,2-dihydroquinoline 6-monooxygenase activity(GO:0018641) chlorophenol 4-monooxygenase activity(GO:0018642) carbon disulfide oxygenase activity(GO:0018643) toluene 2-monooxygenase activity(GO:0018644) 1-hydroxy-2-oxolimonene 1,2-monooxygenase activity(GO:0018646) phenanthrene 1,2-monooxygenase activity(GO:0018647) tetrahydrofuran hydroxylase activity(GO:0018649) styrene monooxygenase activity(GO:0018650) toluene-4-sulfonate monooxygenase activity(GO:0018651) toluene-sulfonate methyl-monooxygenase activity(GO:0018652) 3-methyl-2-oxo-1,2-dihydroquinoline 6-monooxygenase activity(GO:0018653) 2-hydroxy-phenylacetate hydroxylase activity(GO:0018654) 2-oxo-delta3-4,5,5-trimethylcyclopentenylacetyl-CoA 1,2-monooxygenase activity(GO:0018655) phenanthrene 3,4-monooxygenase activity(GO:0018656) toluene 3-monooxygenase activity(GO:0018657) 4-hydroxyphenylacetate,NADH:oxygen oxidoreductase (3-hydroxylating) activity(GO:0018660) limonene monooxygenase activity(GO:0019113) 2-methylnaphthalene hydroxylase activity(GO:0034526) 1-methylnaphthalene hydroxylase activity(GO:0034534) bisphenol A hydroxylase A activity(GO:0034560) salicylate 5-hydroxylase activity(GO:0034785) isobutylamine N-hydroxylase activity(GO:0034791) branched-chain dodecylbenzene sulfonate monooxygenase activity(GO:0034802) 3-HSA hydroxylase activity(GO:0034819) 4-hydroxypyridine-3-hydroxylase activity(GO:0034894) 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase activity(GO:0043719) 6-hydroxynicotinate 3-monooxygenase activity(GO:0043731) tocotrienol omega-hydroxylase activity(GO:0052872) thalianol hydroxylase activity(GO:0080014)
0.0 0.8 GO:0051019 mitogen-activated protein kinase binding(GO:0051019)